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5-Carboxy-2-Chlorobenzeneboronic Acid
Linshang Chemical
|
HS Code |
537332 |
| Name | 5 - Carboxy - 2 - Chlorobenzeneboronic Acid |
| Chemical Formula | C7H6BClO4 |
| Molar Mass | 200.38 g/mol |
| Appearance | Solid (usually white or off - white) |
| Solubility In Water | Slightly soluble |
| Solubility In Organic Solvents | Soluble in some polar organic solvents like DMSO |
| Pka Value | For carboxylic acid group around 4 - 5 |
| Melting Point | Typically in the range of 200 - 220 °C |
| Boiling Point | Decomposes before boiling |
| Reactivity | Reacts with alcohols to form boronate esters, reacts with amines in some cases, and participates in Suzuki - Miyaura coupling reactions |
As an accredited 5-Carboxy-2-Chlorobenzeneboronic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 5 - carboxy - 2 - chlorobenzeneboronic Acid in a sealed, labeled container. |
| Storage | 5 - carboxy - 2 - chlorobenzeneboronic acid should be stored in a cool, dry place. Keep it away from heat sources, direct sunlight, and moisture. Store in a tightly - sealed container to prevent exposure to air, which could potentially lead to oxidation or hydrolysis. Ideal storage conditions are in a temperature - controlled environment, preferably around 2 - 8°C if long - term storage is required. This helps maintain its chemical integrity. |
| Shipping | 5 - carboxy - 2 - chlorobenzeneboronic Acid is shipped in well - sealed containers, protected from moisture and heat. Shipment follows strict chemical transport regulations to ensure safe delivery of this potentially reactive chemical. |
Competitive 5-Carboxy-2-Chlorobenzeneboronic Acid prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 5-Carboxy-2-Chlorobenzeneboronic Acid in China?
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 5-Carboxy-2-Chlorobenzeneboronic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 5-carboxyl-2-chlorophenylboronic acid?
5-Carboxyl-2-bromobenzoic acid is an important chemical raw material in the field of organic synthesis. It is widely used in the field of medicinal chemistry and can be used as a key intermediate to synthesize many drugs with specific pharmacological activities. For example, through a series of chemical reactions, it can be cleverly combined with other compounds to construct drug molecules with complex structures and unique therapeutic effects, or as antibacterial, anti-inflammatory drugs, or anti-tumor drugs, helping humans fight various diseases.
In the field of materials science, this compound also has important functions. It can participate in the preparation of certain functional materials, such as polymer materials with specific properties. With its special chemical structure, polymer materials can be endowed with good thermal stability, mechanical properties or optical properties, etc., and then meet the needs of different fields for special properties of materials, such as electronic devices, optical instruments and other fields.
In the fine chemical industry, 5-carboxyl-2-bromobenzoic acid is often used to synthesize various fine chemicals. These fine chemicals are widely used in the production of coatings, dyes, fragrances and other products. For example, in the preparation of coatings, it can be used as a modifier to optimize the adhesion, corrosion resistance and other properties of coatings; in the synthesis of dyes, it can affect the color, fastness and other characteristics of dyes, contributing to the diversification and high performance of fine chemical products.
In the field of materials science, this compound also has important functions. It can participate in the preparation of certain functional materials, such as polymer materials with specific properties. With its special chemical structure, polymer materials can be endowed with good thermal stability, mechanical properties or optical properties, etc., and then meet the needs of different fields for special properties of materials, such as electronic devices, optical instruments and other fields.
In the fine chemical industry, 5-carboxyl-2-bromobenzoic acid is often used to synthesize various fine chemicals. These fine chemicals are widely used in the production of coatings, dyes, fragrances and other products. For example, in the preparation of coatings, it can be used as a modifier to optimize the adhesion, corrosion resistance and other properties of coatings; in the synthesis of dyes, it can affect the color, fastness and other characteristics of dyes, contributing to the diversification and high performance of fine chemical products.
What are the physical properties of 5-carboxyl-2-chlorophenylboronic acid?
5-Carboxyl-2-bromobenzoic acid is an organic compound with unique physical properties and is widely used in chemical, pharmaceutical and other fields. The following is a detailed description in the style of ancient proverbs:
5-carboxyl-2-bromobenzoic acid, a solid state at room temperature, white in color, like a fine powder, and delicate to the touch. Its melting point is quite high, about [specific value] ℃, and strong heat is required to convert it from solid to liquid. The boiling point of this substance is also considerable, and it boils into a gaseous state under specific conditions.
Looking at its solubility, in water, its solubility is limited, slightly soluble in water, but in organic solvents such as ethanol, ether, acetone, etc., it shows good solubility. The warmth of ethanol, the ethereal of ether, and the activity of acetone can all blend with 5-carboxyl-2-bromobenzoic acid to make it evenly dispersed.
Its density is higher than that of common water, and the texture is slightly heavy. In appearance, its crystal structure is regular and orderly, like a delicate miniature building, highlighting the beauty of nature and chemistry.
The smell of 5-carboxyl-2-bromobenzoic acid is not strong and pungent, but it also has a unique smell, which seems to be slightly sour and mixed with a little indescribable chemical charm. Its stability in the air is still good. Under normal circumstances, it is not easy to undergo obvious chemical changes in a short period of time. However, if it encounters strong light, hot topics or specific chemical substances, it will also cause corresponding reactions.
The physical properties of this substance enable it to play unique functions in many fields, contributing to human production and life, and blooming on the stage of chemistry.
5-carboxyl-2-bromobenzoic acid, a solid state at room temperature, white in color, like a fine powder, and delicate to the touch. Its melting point is quite high, about [specific value] ℃, and strong heat is required to convert it from solid to liquid. The boiling point of this substance is also considerable, and it boils into a gaseous state under specific conditions.
Looking at its solubility, in water, its solubility is limited, slightly soluble in water, but in organic solvents such as ethanol, ether, acetone, etc., it shows good solubility. The warmth of ethanol, the ethereal of ether, and the activity of acetone can all blend with 5-carboxyl-2-bromobenzoic acid to make it evenly dispersed.
Its density is higher than that of common water, and the texture is slightly heavy. In appearance, its crystal structure is regular and orderly, like a delicate miniature building, highlighting the beauty of nature and chemistry.
The smell of 5-carboxyl-2-bromobenzoic acid is not strong and pungent, but it also has a unique smell, which seems to be slightly sour and mixed with a little indescribable chemical charm. Its stability in the air is still good. Under normal circumstances, it is not easy to undergo obvious chemical changes in a short period of time. However, if it encounters strong light, hot topics or specific chemical substances, it will also cause corresponding reactions.
The physical properties of this substance enable it to play unique functions in many fields, contributing to human production and life, and blooming on the stage of chemistry.
What are the synthesis methods of 5-carboxyl-2-chlorophenylboronic acid?
The synthesis methods of 5-hydroxy- 2-mercaptobenzoic acid have been used in ancient times, and there are many kinds. I should use the ancient method to describe it roughly.
First, the method of substitution is based on benzoic acid. Take an appropriate amount of benzoic acid first, put it in a clean kettle, add a specific reagent at a suitable temperature, and introduce hydroxyl groups on the benzene ring. This process requires careful temperature control to observe the progress of the reaction. If the temperature is high, the side reaction will occur and the yield will drop; if the temperature is low, the reaction will be slow and take a long time. After the hydroxyl group is introduced, the mercapto group will be introduced in a subtle way. Or use a sulfur-containing reagent to connect sulfur to the benzene ring under specific conditions to obtain 5-hydroxy- 2-mercaptobenzoic acid. The key to this approach lies in the precise control of the reaction conditions at each step. The dosage of reagents, the temperature and time of the reaction are all related to success or failure.
Second, start with other aromatic compounds. If you choose a specific phenolic compound, there is already a genus of hydroxyl groups on the benzene ring, but the position may be different. First, chemically adjust the position of the hydroxyl group to the desired place. Next, follow ingenious steps to introduce sulfhydryl and carboxyl groups. In this way, various reactions such as condensation and substitution can be used to make each functional group arrive in sequence and finally form the target product. This way requires a good grasp of various reaction mechanisms, and close connection between each step to be able to synthesize smoothly.
Third, with the help of the transformation of natural products. There are natural things in the world, and their structure is slightly related to 5-hydroxyl-2-mercaptobenzoic acid. Take this natural product and modify it gradually by chemical means. Or hydrolysis, oxidation, or reduction, change its existing functional groups, add or delete atoms and groups, and gradually reach the target structure. Although the raw materials are natural, the process requirements are extremely high. It is necessary to be familiar with the characteristics of natural products and take advantage of the situation to obtain this synthetic product from natural sources.
All this synthesis method requires chemical ingenuity and experimental care. All the details cannot be ignored. From the selection of raw materials, to the control of the reaction, and then to the separation of the product, the synthesis of 5-hydroxy- 2-mercaptobenzoic acid can be achieved.
First, the method of substitution is based on benzoic acid. Take an appropriate amount of benzoic acid first, put it in a clean kettle, add a specific reagent at a suitable temperature, and introduce hydroxyl groups on the benzene ring. This process requires careful temperature control to observe the progress of the reaction. If the temperature is high, the side reaction will occur and the yield will drop; if the temperature is low, the reaction will be slow and take a long time. After the hydroxyl group is introduced, the mercapto group will be introduced in a subtle way. Or use a sulfur-containing reagent to connect sulfur to the benzene ring under specific conditions to obtain 5-hydroxy- 2-mercaptobenzoic acid. The key to this approach lies in the precise control of the reaction conditions at each step. The dosage of reagents, the temperature and time of the reaction are all related to success or failure.
Second, start with other aromatic compounds. If you choose a specific phenolic compound, there is already a genus of hydroxyl groups on the benzene ring, but the position may be different. First, chemically adjust the position of the hydroxyl group to the desired place. Next, follow ingenious steps to introduce sulfhydryl and carboxyl groups. In this way, various reactions such as condensation and substitution can be used to make each functional group arrive in sequence and finally form the target product. This way requires a good grasp of various reaction mechanisms, and close connection between each step to be able to synthesize smoothly.
Third, with the help of the transformation of natural products. There are natural things in the world, and their structure is slightly related to 5-hydroxyl-2-mercaptobenzoic acid. Take this natural product and modify it gradually by chemical means. Or hydrolysis, oxidation, or reduction, change its existing functional groups, add or delete atoms and groups, and gradually reach the target structure. Although the raw materials are natural, the process requirements are extremely high. It is necessary to be familiar with the characteristics of natural products and take advantage of the situation to obtain this synthetic product from natural sources.
All this synthesis method requires chemical ingenuity and experimental care. All the details cannot be ignored. From the selection of raw materials, to the control of the reaction, and then to the separation of the product, the synthesis of 5-hydroxy- 2-mercaptobenzoic acid can be achieved.
What are the precautions for 5-carboxyl-2-chlorophenylboronic acid in storage and transportation?
5-Hydroxy-2-mercaptobenzoic acid is an important chemical substance, and many points must be paid attention to during storage and transportation.
Its properties may be unstable, and it may deteriorate in case of light, heat, moisture and other factors. When storing, it is advisable to choose a cool, dry and ventilated place, away from direct sunlight and high temperature environment. If the temperature is too high, it may cause it to decompose, the humidity is too high, or it may deliquescent, which will affect the quality and performance.
This substance may be corrosive and toxic, and protective measures must be taken during transportation and storage. Staff must wear appropriate protective equipment, such as protective clothing, gloves, goggles, etc., to prevent contact with the human body and cause injury. In case of inadvertent contact, rinse with plenty of water immediately and seek medical attention according to the specific situation.
Packaging is also crucial. Corrosive and sealed packaging materials should be used to ensure that there is no risk of leakage during transportation. Leakage will not only cause material loss, but also endanger the environment and personnel safety. During transportation, it is also necessary to prevent package damage, collision and vibration to avoid affecting the stability of the material.
Furthermore, 5-hydroxy- 2-mercaptobenzoic acid may chemically react with other substances, so when storing and transporting, it should not be mixed with oxidizing, alkaline and other substances to avoid dangerous reactions.
The storage and transportation of 5-hydroxy- 2-mercaptobenzoic acid requires careful attention to environmental conditions, protective measures, packaging, and mixed transportation to ensure its safety and quality.
Its properties may be unstable, and it may deteriorate in case of light, heat, moisture and other factors. When storing, it is advisable to choose a cool, dry and ventilated place, away from direct sunlight and high temperature environment. If the temperature is too high, it may cause it to decompose, the humidity is too high, or it may deliquescent, which will affect the quality and performance.
This substance may be corrosive and toxic, and protective measures must be taken during transportation and storage. Staff must wear appropriate protective equipment, such as protective clothing, gloves, goggles, etc., to prevent contact with the human body and cause injury. In case of inadvertent contact, rinse with plenty of water immediately and seek medical attention according to the specific situation.
Packaging is also crucial. Corrosive and sealed packaging materials should be used to ensure that there is no risk of leakage during transportation. Leakage will not only cause material loss, but also endanger the environment and personnel safety. During transportation, it is also necessary to prevent package damage, collision and vibration to avoid affecting the stability of the material.
Furthermore, 5-hydroxy- 2-mercaptobenzoic acid may chemically react with other substances, so when storing and transporting, it should not be mixed with oxidizing, alkaline and other substances to avoid dangerous reactions.
The storage and transportation of 5-hydroxy- 2-mercaptobenzoic acid requires careful attention to environmental conditions, protective measures, packaging, and mixed transportation to ensure its safety and quality.
What is the market price of 5-carboxyl-2-chlorophenylboronic acid?
The market price of 5-carboxyl-2-bromobenzoic acid, depending on the current market, is roughly between a few and a few tens of yuan per gram. This price often varies due to quality, purity, yield, supply and demand.
If its quality is excellent and its purity is extremely high, it will be used in fine chemical or pharmaceutical research and development, and its price will be high, or tens of yuan per gram. Due to such fields, the purity and quality requirements are strict, the preparation method is also complex, and the cost is high.
If used in general industrial production, the purity requirements are slightly lower, and the market price is several yuan per gram. At this time, considering large-scale production, the output is large, and the cost is shared, the price will be lower.
In addition, market supply and demand are also the key. If there are many people seeking for a while, the supply will be difficult to meet the demand, and the price will rise; if there is excess capacity, the demand will be weak, and the price will also drop.
And the prices set by different suppliers are also different. Well-known large factories, due to brand and quality control, the price may be high; emerging small factories, for market competition, or low-price promotion. To know the exact market price, you need to study the market carefully and compare the quotations of different suppliers to get the actual price.
If its quality is excellent and its purity is extremely high, it will be used in fine chemical or pharmaceutical research and development, and its price will be high, or tens of yuan per gram. Due to such fields, the purity and quality requirements are strict, the preparation method is also complex, and the cost is high.
If used in general industrial production, the purity requirements are slightly lower, and the market price is several yuan per gram. At this time, considering large-scale production, the output is large, and the cost is shared, the price will be lower.
In addition, market supply and demand are also the key. If there are many people seeking for a while, the supply will be difficult to meet the demand, and the price will rise; if there is excess capacity, the demand will be weak, and the price will also drop.
And the prices set by different suppliers are also different. Well-known large factories, due to brand and quality control, the price may be high; emerging small factories, for market competition, or low-price promotion. To know the exact market price, you need to study the market carefully and compare the quotations of different suppliers to get the actual price.
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