Linshang Chemical
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5-Chloro-1,2-Dibromo-3-Fluorobenzene
Linshang Chemical
|
HS Code |
177257 |
| Chemical Formula | C6H2Br2ClF |
| Appearance | Typically a colorless to pale - yellow liquid (assumed, as no common appearance data found, but common for such halobenzene derivatives) |
| Boiling Point | Estimated around 240 - 260°C (educated estimate based on similar halogenated benzenes) |
| Melting Point | No common data, but expected to be in a relatively low range considering the structure, perhaps around - 20 to 0°C |
| Density | Estimated around 2.0 - 2.2 g/cm³ (comparable to other poly - halogenated benzenes) |
| Solubility In Water | Very low, likely less than 0.1 g/L due to its non - polar nature |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform, toluene |
| Vapor Pressure | Low vapor pressure at room temperature, estimated in the range of 10⁻³ - 10⁻⁵ mmHg |
| Flash Point | No common data, but expected to be relatively high, perhaps above 100°C due to its halogen - rich nature |
As an accredited 5-Chloro-1,2-Dibromo-3-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 5 - chloro - 1,2 - dibromo - 3 - fluorobenzene in 100 - gram bottles for chemical packaging. |
| Storage | 5 - chloro - 1,2 - dibromo - 3 - fluorobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly closed container, preferably made of corrosion - resistant materials, to prevent leakage and exposure to air or moisture, which could potentially cause decomposition or reactions. |
| Shipping | 5 - chloro - 1,2 - dibromo - 3 - fluorobenzene, a chemical, should be shipped in sealed, corrosion - resistant containers. It must comply with hazardous material shipping regulations, ensuring proper labeling and secure handling during transit. |
Competitive 5-Chloro-1,2-Dibromo-3-Fluorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
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As a leading 5-Chloro-1,2-Dibromo-3-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the chemical properties of 5-chloro-1,2-dibromo-3-fluorobenzene?
5-Alkane-1,2-diol-3-enol is an organic compound with rich and diverse chemical properties.
From the perspective of hydroxyl groups, 5-alkane-1,2-diol-3-enol contains two hydroxyl groups, which have typical properties of alcohols. First, a substitution reaction can occur. If it interacts with hydrohalic acid, the hydroxyl group will be replaced by a halogen atom. Take hydrobromic acid as an example. During the reaction, the oxygen atom in the hydroxyl group will combine with the hydrogen atom in the hydrobromic acid, and then the bromine atom will replace the hydroxyl group to form the corresponding halogenated hydrocarbon and water. Second, it can carry out esterification reaction. Under the condition of concentrated sulfuric acid catalysis and heating, the hydroxyl groups of 5-alkane-1,2-diol-3-enol can react with carboxylic acids to form esters and water. In this process, the acid dehydrogenates the alcohol. Third, it can also participate in the oxidation reaction. During moderate oxidation, the primary alcohol hydroxyl group will be converted to an aldehyde group, and the secondary alcohol hydroxyl group will become a carbonyl group. If the oxidation is excessive, the aldehyde group will be further oxidized to a carboxyl group.
Look at the carbon-carbon double bond, which is another key functional group of the compound. The carbon-carbon double bond determines its ability to undergo an addition reaction. If it reacts with a halogen elemental substance, such as carbon tetrachloride solution of bromine, the bromine molecule will be split into two bromine atoms, which are added to the two carbon atoms of the carbon-carbon double bond, so that the double bond becomes a single bond, forming a dibromo substitute. Addition reaction with hydrogen under the action of a catalyst can convert the carbon-carbon double bond into a single bond to achieve hydroreduction. At the same time, the carbon-carbon double bond is easily oxidized by strong oxidants, such as acidic potassium permanganate solution, the double bond will break, and different oxidation products will be generated according to the different groups connected by the double bond.
In addition, the two hydroxyl groups of 5-alkane-1,2-diol-3-enol interact with the carbon-carbon double bond, making its properties more unique. For example, the hydroxyl group can change the electron cloud density of the carbon atoms connected to it, which indirectly affects the activity of the carbon-carbon double bond; the existence of the carbon-carbon double bond also slightly changes the acidity of the hydroxyl group. The complexity and uniqueness of the properties of this compound make it have important applications and research value in organic synthesis, medicinal chemistry and other fields.
From the perspective of hydroxyl groups, 5-alkane-1,2-diol-3-enol contains two hydroxyl groups, which have typical properties of alcohols. First, a substitution reaction can occur. If it interacts with hydrohalic acid, the hydroxyl group will be replaced by a halogen atom. Take hydrobromic acid as an example. During the reaction, the oxygen atom in the hydroxyl group will combine with the hydrogen atom in the hydrobromic acid, and then the bromine atom will replace the hydroxyl group to form the corresponding halogenated hydrocarbon and water. Second, it can carry out esterification reaction. Under the condition of concentrated sulfuric acid catalysis and heating, the hydroxyl groups of 5-alkane-1,2-diol-3-enol can react with carboxylic acids to form esters and water. In this process, the acid dehydrogenates the alcohol. Third, it can also participate in the oxidation reaction. During moderate oxidation, the primary alcohol hydroxyl group will be converted to an aldehyde group, and the secondary alcohol hydroxyl group will become a carbonyl group. If the oxidation is excessive, the aldehyde group will be further oxidized to a carboxyl group.
Look at the carbon-carbon double bond, which is another key functional group of the compound. The carbon-carbon double bond determines its ability to undergo an addition reaction. If it reacts with a halogen elemental substance, such as carbon tetrachloride solution of bromine, the bromine molecule will be split into two bromine atoms, which are added to the two carbon atoms of the carbon-carbon double bond, so that the double bond becomes a single bond, forming a dibromo substitute. Addition reaction with hydrogen under the action of a catalyst can convert the carbon-carbon double bond into a single bond to achieve hydroreduction. At the same time, the carbon-carbon double bond is easily oxidized by strong oxidants, such as acidic potassium permanganate solution, the double bond will break, and different oxidation products will be generated according to the different groups connected by the double bond.
In addition, the two hydroxyl groups of 5-alkane-1,2-diol-3-enol interact with the carbon-carbon double bond, making its properties more unique. For example, the hydroxyl group can change the electron cloud density of the carbon atoms connected to it, which indirectly affects the activity of the carbon-carbon double bond; the existence of the carbon-carbon double bond also slightly changes the acidity of the hydroxyl group. The complexity and uniqueness of the properties of this compound make it have important applications and research value in organic synthesis, medicinal chemistry and other fields.
What are the physical properties of 5-chloro-1,2-dibromo-3-fluorobenzene?
5-Alkane-1,2-dichloro-3-fluorotoluene is an organic compound with the following physical properties:
Looking at its properties, under normal temperature and pressure, this substance is mostly colorless to light yellow liquid, with clear texture and good flow performance. With the sense of smell, it can be observed that it has a special aromatic smell, but the smell may vary from the senses due to different concentrations. When the concentration is high, it may be more pungent.
When it comes to boiling point, the boiling point of this compound will vary according to its precise chemical structure and the environmental pressure conditions. Generally speaking, in a standard atmospheric pressure environment, its boiling point is within a certain temperature range. This characteristic makes it unique in operations such as heating or distillation separation. At a suitable temperature range, gas-liquid conversion can be realized, thereby achieving separation from other substances.
Melting point also depends on its own chemical structure, usually a specific temperature value. When below the melting point temperature, the substance will change from liquid to solid, showing a crystalline or solid bulk. This melting point characteristic is of great significance for its storage and transportation conditions. It is necessary to consider the ambient temperature to avoid changing its state due to improper temperature, which affects the quality and service efficiency.
Density is also one of the important physical properties. Compared with water, the density of 5-alkane-1,2-dichloro-3-fluorotoluene may be different. This difference determines its distribution when mixed with water. If the density is greater than that of water, it will sink to the bottom of the water; otherwise, it will float on the water surface. This property is crucial in the chemical reaction or separation process involving the aqueous phase, and a reasonable separation scheme can be designed accordingly.
In terms of solubility, the substance has good solubility in organic solvents, and organic solvents such as common ethanol, ether, and acetone can be miscible with it. However, the solubility in water is very small, and this difference in solubility provides an important basis for its application in chemical synthesis, purification and purification. The difference in solubility of different solvents can be used to realize the separation, purification and reaction of the substance.
Looking at its properties, under normal temperature and pressure, this substance is mostly colorless to light yellow liquid, with clear texture and good flow performance. With the sense of smell, it can be observed that it has a special aromatic smell, but the smell may vary from the senses due to different concentrations. When the concentration is high, it may be more pungent.
When it comes to boiling point, the boiling point of this compound will vary according to its precise chemical structure and the environmental pressure conditions. Generally speaking, in a standard atmospheric pressure environment, its boiling point is within a certain temperature range. This characteristic makes it unique in operations such as heating or distillation separation. At a suitable temperature range, gas-liquid conversion can be realized, thereby achieving separation from other substances.
Melting point also depends on its own chemical structure, usually a specific temperature value. When below the melting point temperature, the substance will change from liquid to solid, showing a crystalline or solid bulk. This melting point characteristic is of great significance for its storage and transportation conditions. It is necessary to consider the ambient temperature to avoid changing its state due to improper temperature, which affects the quality and service efficiency.
Density is also one of the important physical properties. Compared with water, the density of 5-alkane-1,2-dichloro-3-fluorotoluene may be different. This difference determines its distribution when mixed with water. If the density is greater than that of water, it will sink to the bottom of the water; otherwise, it will float on the water surface. This property is crucial in the chemical reaction or separation process involving the aqueous phase, and a reasonable separation scheme can be designed accordingly.
In terms of solubility, the substance has good solubility in organic solvents, and organic solvents such as common ethanol, ether, and acetone can be miscible with it. However, the solubility in water is very small, and this difference in solubility provides an important basis for its application in chemical synthesis, purification and purification. The difference in solubility of different solvents can be used to realize the separation, purification and reaction of the substance.
What are the main uses of 5-chloro-1,2-dibromo-3-fluorobenzene?
The main uses of 5-% -1,2-dichloro-3-fluorotoluene are as follows:
This compound has a high value in the field of synthesis. It can be used in the synthesis of polymers. Due to the presence of fluorine and chlorine atoms in the molecule, it can give the specific biological activity of the compound. For example, in the synthesis of some antibacterial compounds, 5-% -1,2-dichloro-3-fluorotoluene can be serially reacted to introduce a specific function, so as to create a molecule with high antibacterial activity. The properties of its fluorine atoms can affect the binding ability of the target protein of the compound and enhance the antibacterial effect.
It also plays an important role in the research of antibacterial substances. It can be used as a raw material for the synthesis of new types of crops. Due to its characteristics, the synthesized chemicals may have high-quality, bacterial or weeding properties. For example, by using this starting material, through chemical repair, specific crops can be obtained. Products with specific effects on diseases and diseases can be obtained, and because of their quality, they can maintain a high-quality retention period in the environment, which not only effectively prevents and treats diseases, but also reduces the environmental impact.
In addition, in the field of materials science, 5-% 1,2-dichloro-3-fluorotoluene also has certain uses. It can be used in the synthesis of polymer materials with special properties. In polymerization reactions, the introduction of plastics or modifications into polymers can improve the resistance and chemical resistance of materials. For example, in the synthesis of some high-performance engineering plastics, the addition of this compound-derived material can enhance the performance of plastics in high-performance, chemical and corrosion environments, and expand their application in high-end fields such as aerospace and electronics.
This compound has a high value in the field of synthesis. It can be used in the synthesis of polymers. Due to the presence of fluorine and chlorine atoms in the molecule, it can give the specific biological activity of the compound. For example, in the synthesis of some antibacterial compounds, 5-% -1,2-dichloro-3-fluorotoluene can be serially reacted to introduce a specific function, so as to create a molecule with high antibacterial activity. The properties of its fluorine atoms can affect the binding ability of the target protein of the compound and enhance the antibacterial effect.
It also plays an important role in the research of antibacterial substances. It can be used as a raw material for the synthesis of new types of crops. Due to its characteristics, the synthesized chemicals may have high-quality, bacterial or weeding properties. For example, by using this starting material, through chemical repair, specific crops can be obtained. Products with specific effects on diseases and diseases can be obtained, and because of their quality, they can maintain a high-quality retention period in the environment, which not only effectively prevents and treats diseases, but also reduces the environmental impact.
In addition, in the field of materials science, 5-% 1,2-dichloro-3-fluorotoluene also has certain uses. It can be used in the synthesis of polymer materials with special properties. In polymerization reactions, the introduction of plastics or modifications into polymers can improve the resistance and chemical resistance of materials. For example, in the synthesis of some high-performance engineering plastics, the addition of this compound-derived material can enhance the performance of plastics in high-performance, chemical and corrosion environments, and expand their application in high-end fields such as aerospace and electronics.
What are the synthesis methods of 5-chloro-1,2-dibromo-3-fluorobenzene?
The synthesis method of 5-bromo-1,2-dichloro-3-fluorobenzene, although the ancient book "Tiangong Kaiwu" does not contain the synthesis method of this specific compound, it can be deduced from the wisdom of the ancient chemical process.
Ancient chemical processes involve alchemy, metallurgy, ceramics, etc. To obtain this halogenated aromatic hydrocarbon, you can first find suitable benzene derivatives as starting materials. Or find natural benzene-containing substances, such as some plant extracts, coal tar fractions, and separate and purify the parent body of benzene.
It is assumed that benzene is used as the starting material, and bromine, chlorine and fluorine atoms are to be introduced. Although the ancients did not have modern advanced halogenation reagents, they could borrow what was available at that time. In the halogenation reaction, if you want to introduce bromine atoms, you can try to co-heat potassium bromide with concentrated sulfuric acid to generate bromine gas, so that benzene and bromine gas can react under suitable conditions. Although there was no precise catalyst concept at that time, it was found that iron powder could accelerate the reaction and generate bromobenzene after many tests.
Introduce chlorine atoms, or you can follow the method of preparing chlorine gas, and co-heat concentrated hydrochloric acid with manganese dioxide to obtain chlorine gas, so that bromobenzene reacts with chlorine gas to obtain benzene derivatives containing bromine and chlorine. As for the introduction of fluorine atoms, it is really difficult. Due to the extremely high activity of fluorine, it was difficult for the ancients to find suitable reagents. It is conceivable to first prepare intermediates containing active functional groups, such as halogenated alkanes, and then react with fluorine-containing salts, such as potassium fluoride, in appropriate solvents to try to introduce fluorine atoms into the molecule. Although the process is difficult, with the tenacity of the ancients to explore the spirit, or to gradually optimize the reaction conditions, the path to synthesize 5-bromo-1,2-dichloro-3-fluorobenzene can be explored.
Ancient chemical processes involve alchemy, metallurgy, ceramics, etc. To obtain this halogenated aromatic hydrocarbon, you can first find suitable benzene derivatives as starting materials. Or find natural benzene-containing substances, such as some plant extracts, coal tar fractions, and separate and purify the parent body of benzene.
It is assumed that benzene is used as the starting material, and bromine, chlorine and fluorine atoms are to be introduced. Although the ancients did not have modern advanced halogenation reagents, they could borrow what was available at that time. In the halogenation reaction, if you want to introduce bromine atoms, you can try to co-heat potassium bromide with concentrated sulfuric acid to generate bromine gas, so that benzene and bromine gas can react under suitable conditions. Although there was no precise catalyst concept at that time, it was found that iron powder could accelerate the reaction and generate bromobenzene after many tests.
Introduce chlorine atoms, or you can follow the method of preparing chlorine gas, and co-heat concentrated hydrochloric acid with manganese dioxide to obtain chlorine gas, so that bromobenzene reacts with chlorine gas to obtain benzene derivatives containing bromine and chlorine. As for the introduction of fluorine atoms, it is really difficult. Due to the extremely high activity of fluorine, it was difficult for the ancients to find suitable reagents. It is conceivable to first prepare intermediates containing active functional groups, such as halogenated alkanes, and then react with fluorine-containing salts, such as potassium fluoride, in appropriate solvents to try to introduce fluorine atoms into the molecule. Although the process is difficult, with the tenacity of the ancients to explore the spirit, or to gradually optimize the reaction conditions, the path to synthesize 5-bromo-1,2-dichloro-3-fluorobenzene can be explored.
What should be paid attention to when storing and transporting 5-chloro-1,2-dibromo-3-fluorobenzene?
For 5-alkane-1,2-dibromo-3-chloropropene, there are all kinds of things that should be paid attention to when it is stored or transported.
The first thing to pay attention to is its physical properties. This substance has special chemical properties and is easy to react with other substances. Therefore, in the storage device, the appropriate material must be selected. It is necessary to prevent it from reacting chemically with the wall of the device, causing damage to the substance or the device. If it is stored in glass, it is necessary to check whether there is any potential reaction with the glass components. If so, it is easy to use other devices, such as specially selected plastic or metal containers, but its compatibility must also be carefully examined.
The second is the temperature and humidity of the environment. If the temperature is too high, it may cause its volatilization to increase, and even cause dangerous chemical reactions; if the humidity is too high, it may cause it to deteriorate due to moisture. Therefore, in the storage place, the temperature should be controlled in a suitable range, usually in a cool place, and the humidity should also be stable within a reasonable range. Temperature and humidity monitoring devices can be set up to check from time to time. If there is any deviation, adjust quickly.
Furthermore, prevent its leakage. During transportation, the packaging must be sturdy and tight to prevent leakage. Loading and unloading vehicles should be handled with caution to avoid damage to the packaging due to shock and pressure. If it is unfortunate to leak, deal with it quickly according to the established emergency measures, evacuate the surrounding crowd, set up warning signs, prohibit people from approaching, and clean it up quickly to prevent its spread from causing greater harm.
It is also necessary to pay attention to its isolation from other substances. This substance should not be stored and transported with oxidizing and reducing substances to avoid violent reactions. In case of fire sources, or the risk of combustion or explosion, fireworks are strictly prohibited in the place of storage and transportation, and fire extinguishers and emergency equipment are prepared for fear. All of these are important for the storage and transportation of 5-alkane-1,2-dibromo-3-chloropropene. Be careful, so that the security is safe.
The first thing to pay attention to is its physical properties. This substance has special chemical properties and is easy to react with other substances. Therefore, in the storage device, the appropriate material must be selected. It is necessary to prevent it from reacting chemically with the wall of the device, causing damage to the substance or the device. If it is stored in glass, it is necessary to check whether there is any potential reaction with the glass components. If so, it is easy to use other devices, such as specially selected plastic or metal containers, but its compatibility must also be carefully examined.
The second is the temperature and humidity of the environment. If the temperature is too high, it may cause its volatilization to increase, and even cause dangerous chemical reactions; if the humidity is too high, it may cause it to deteriorate due to moisture. Therefore, in the storage place, the temperature should be controlled in a suitable range, usually in a cool place, and the humidity should also be stable within a reasonable range. Temperature and humidity monitoring devices can be set up to check from time to time. If there is any deviation, adjust quickly.
Furthermore, prevent its leakage. During transportation, the packaging must be sturdy and tight to prevent leakage. Loading and unloading vehicles should be handled with caution to avoid damage to the packaging due to shock and pressure. If it is unfortunate to leak, deal with it quickly according to the established emergency measures, evacuate the surrounding crowd, set up warning signs, prohibit people from approaching, and clean it up quickly to prevent its spread from causing greater harm.
It is also necessary to pay attention to its isolation from other substances. This substance should not be stored and transported with oxidizing and reducing substances to avoid violent reactions. In case of fire sources, or the risk of combustion or explosion, fireworks are strictly prohibited in the place of storage and transportation, and fire extinguishers and emergency equipment are prepared for fear. All of these are important for the storage and transportation of 5-alkane-1,2-dibromo-3-chloropropene. Be careful, so that the security is safe.
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