Linshang Chemical
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5-Chloro-2,3-Difluoronitrobenzene
Linshang Chemical
|
HS Code |
741051 |
| Chemical Formula | C6H2ClF2NO2 |
| Appearance | Typically a colorless to light yellow liquid or solid |
| Boiling Point | Data may vary, but generally in a certain range related to its molecular structure |
| Melting Point | Specific value depending on purity and structure |
| Density | A density value related to its molecular packing |
| Solubility | Solubility characteristics in different solvents like organic solvents |
| Vapor Pressure | A value indicating its tendency to vaporize |
| Flash Point | A temperature at which it can ignite in air |
| Stability | Stability under normal and certain storage conditions |
As an accredited 5-Chloro-2,3-Difluoronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 5 - chloro - 2,3 - difluoronitrobenzene: Packed in 500g bottles for safe storage. |
| Storage | 5 - Chloro - 2,3 - difluoronitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly closed container, preferably made of corrosion - resistant materials. Avoid exposure to moisture as it may cause decomposition. Label the storage container clearly for easy identification and to ensure proper handling. |
| Shipping | 5 - Chloro - 2,3 - difluoronitrobenzene, a chemical, should be shipped in well - sealed, corrosion - resistant containers. It must comply with hazardous chemical shipping regulations, ensuring proper labeling and safe handling during transit. |
Competitive 5-Chloro-2,3-Difluoronitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 5-Chloro-2,3-Difluoronitrobenzene in China?
As a trusted 5-Chloro-2,3-Difluoronitrobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 5-Chloro-2,3-Difluoronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 5-chloro-2,3-difluoronitrobenzene?
5-Bromo-2,3-diethoxybenzoylbenzene, which has important uses in various fields.
In the field of medicinal chemistry, it is often a key intermediate in the synthesis of many drugs. Due to its special chemical structure, it can interact with specific targets in organisms. For example, by introducing it into the molecular framework of a drug through clever chemical reactions, it can give the drug a unique pharmacological activity. It may enhance the affinity of the drug to specific disease-related receptors, thereby enhancing the efficacy of drug treatment such as cardiovascular diseases and neurological diseases.
In the field of materials science, 5-bromo-2,3-diethoxybenzoylbenzene is also of significant value. Due to its structural properties, it can participate in the polymerization of polymer materials. With this compound as a monomer or crosslinking agent, polymer materials with special properties can be prepared. Such as the preparation of polymer films with excellent optical properties, or the manufacture of engineering plastics with excellent mechanical properties and good chemical stability, it is widely used in electronic devices, optical instruments and other fields.
Furthermore, in the field of organic synthesis chemistry, it is an important cornerstone for the construction of complex organic molecules. Chemists can utilize the activity of their functional groups to achieve precise modification and expansion of molecular structures through various classical organic reactions, such as nucleophilic substitution, electrophilic addition, etc., and synthesize a series of organic compounds with novel structures and unique functions, injecting new vitality into the development of organic synthetic chemistry.
In the field of medicinal chemistry, it is often a key intermediate in the synthesis of many drugs. Due to its special chemical structure, it can interact with specific targets in organisms. For example, by introducing it into the molecular framework of a drug through clever chemical reactions, it can give the drug a unique pharmacological activity. It may enhance the affinity of the drug to specific disease-related receptors, thereby enhancing the efficacy of drug treatment such as cardiovascular diseases and neurological diseases.
In the field of materials science, 5-bromo-2,3-diethoxybenzoylbenzene is also of significant value. Due to its structural properties, it can participate in the polymerization of polymer materials. With this compound as a monomer or crosslinking agent, polymer materials with special properties can be prepared. Such as the preparation of polymer films with excellent optical properties, or the manufacture of engineering plastics with excellent mechanical properties and good chemical stability, it is widely used in electronic devices, optical instruments and other fields.
Furthermore, in the field of organic synthesis chemistry, it is an important cornerstone for the construction of complex organic molecules. Chemists can utilize the activity of their functional groups to achieve precise modification and expansion of molecular structures through various classical organic reactions, such as nucleophilic substitution, electrophilic addition, etc., and synthesize a series of organic compounds with novel structures and unique functions, injecting new vitality into the development of organic synthetic chemistry.
What are the synthesis methods of 5-chloro-2,3-difluoronitrobenzene?
The synthesis method of 5-bromo-2,3-diethoxybenzoylbenzene is not directly described in "Tiangong Kaiwu", but it can be deduced from the ancient chemical process ideas and principles.
Ancient chemical processes mostly originated from the extraction and transformation of natural substances. To synthesize this substance, you can start from natural substances with similar structures. First look for natural compounds containing benzene rings and groups such as bromine and ethoxy, such as certain plant extracts or minerals.
First, substitution reactions can be used. Using a compound containing a benzene ring as a substrate, a brominating agent, such as liquid bromine and a suitable catalyst, such as iron filings or iron tribromide, is selected to carry out a bromination reaction, so that the bromine atom replaces the hydrogen atom at a specific position of the benzene ring to obtain a bromobenzene derivative. This step requires controlling the reaction temperature, time and the ratio of the reactants. Due to the high activity of bromination reaction, it is easy to cause polybromination by-products.
Second, the ethoxy group is introduced. The Williamson ether synthesis method can be used to react a halogenated benzene derivative with sodium ethanol. Mix halogenated benzene and sodium ethanol in a suitable solvent, such as DMF or DMSO, and heat and stir to replace the halogen atom with an ethoxy group to obtain a benzene This reaction requires an anhydrous environment, because water will hydrolyze sodium ethanol, reducing the reaction efficiency.
Third, to construct a benzoyl structure. It can be achieved by the acylation reaction of the corresponding benzoic acid derivative. The benzoyl chloride is reacted with the above-mentioned bromine and ethoxy benzene derivatives under the action of Lewis acid catalyst, such as anhydrous aluminum trichloride, in a suitable organic solvent, such as dichloromethane, to form the target product 5-bromo-2,3-diethoxybenzoyl benzene. After the reaction, it needs to be separated and purified, such as extraction, column chromatography and other means, to obtain a pure product.
Although this synthesis method is not completely based on ancient methods, the combination of ancient chemical wisdom and modern chemical knowledge can provide a feasible way for the synthesis of 5-bromo-2,3-diethoxybenzoylbenzene.
Ancient chemical processes mostly originated from the extraction and transformation of natural substances. To synthesize this substance, you can start from natural substances with similar structures. First look for natural compounds containing benzene rings and groups such as bromine and ethoxy, such as certain plant extracts or minerals.
First, substitution reactions can be used. Using a compound containing a benzene ring as a substrate, a brominating agent, such as liquid bromine and a suitable catalyst, such as iron filings or iron tribromide, is selected to carry out a bromination reaction, so that the bromine atom replaces the hydrogen atom at a specific position of the benzene ring to obtain a bromobenzene derivative. This step requires controlling the reaction temperature, time and the ratio of the reactants. Due to the high activity of bromination reaction, it is easy to cause polybromination by-products.
Second, the ethoxy group is introduced. The Williamson ether synthesis method can be used to react a halogenated benzene derivative with sodium ethanol. Mix halogenated benzene and sodium ethanol in a suitable solvent, such as DMF or DMSO, and heat and stir to replace the halogen atom with an ethoxy group to obtain a benzene This reaction requires an anhydrous environment, because water will hydrolyze sodium ethanol, reducing the reaction efficiency.
Third, to construct a benzoyl structure. It can be achieved by the acylation reaction of the corresponding benzoic acid derivative. The benzoyl chloride is reacted with the above-mentioned bromine and ethoxy benzene derivatives under the action of Lewis acid catalyst, such as anhydrous aluminum trichloride, in a suitable organic solvent, such as dichloromethane, to form the target product 5-bromo-2,3-diethoxybenzoyl benzene. After the reaction, it needs to be separated and purified, such as extraction, column chromatography and other means, to obtain a pure product.
Although this synthesis method is not completely based on ancient methods, the combination of ancient chemical wisdom and modern chemical knowledge can provide a feasible way for the synthesis of 5-bromo-2,3-diethoxybenzoylbenzene.
What are the physical properties of 5-chloro-2,3-difluoronitrobenzene?
5-Bromo-2,3-diethoxybenzaldehyde, which is slightly yellow to light brown crystalline powder. Its melting point is a specific value, about [X] ° C. The melting point determines that it changes from solid to liquid at the corresponding temperature. This property is crucial in separation, purification and identification. Its purity can be verified by measuring the melting point. If it contains more impurities, the melting point will be reduced and the melting range will be widened.
It is slightly soluble in water, but easily soluble in organic solvents such as ethanol and ether. This difference in solubility is due to its molecular structure, where polar groups in the molecule interact with non-polar parts. Water is a polar solvent, and the benzene ring and other non-polar structures in the molecule of this substance account for a large proportion, resulting in weak force between it and water molecules, making it difficult to dissolve in water; the polarity of organic solvents such as ethanol and ether is adapted to the molecular structure, which can form a suitable force with the molecule of this substance, making it easy to dissolve.
In terms of chemical stability, because it contains an aldehyde group, it is an active functional group and is easily oxidized. In case of strong oxidizing agents such as potassium permanganate, the aldehyde group will be oxidized to a carboxyl group to generate 5-bromo-2,3-diethoxybenzoic acid. In addition, the aldehyde group can also undergo a reduction reaction, and can be converted into corresponding alcohols under the action of suitable reducing agents such as sodium borohydride. The bromine atom on the benzene ring also has certain reactivity. Under certain conditions, it can undergo substitution reactions, such as with nucleophiles, and the bromine atom can be replaced by other groups, thus deriving a variety of compounds. This property provides a variety of paths for organic synthesis.
It is slightly soluble in water, but easily soluble in organic solvents such as ethanol and ether. This difference in solubility is due to its molecular structure, where polar groups in the molecule interact with non-polar parts. Water is a polar solvent, and the benzene ring and other non-polar structures in the molecule of this substance account for a large proportion, resulting in weak force between it and water molecules, making it difficult to dissolve in water; the polarity of organic solvents such as ethanol and ether is adapted to the molecular structure, which can form a suitable force with the molecule of this substance, making it easy to dissolve.
In terms of chemical stability, because it contains an aldehyde group, it is an active functional group and is easily oxidized. In case of strong oxidizing agents such as potassium permanganate, the aldehyde group will be oxidized to a carboxyl group to generate 5-bromo-2,3-diethoxybenzoic acid. In addition, the aldehyde group can also undergo a reduction reaction, and can be converted into corresponding alcohols under the action of suitable reducing agents such as sodium borohydride. The bromine atom on the benzene ring also has certain reactivity. Under certain conditions, it can undergo substitution reactions, such as with nucleophiles, and the bromine atom can be replaced by other groups, thus deriving a variety of compounds. This property provides a variety of paths for organic synthesis.
What is the market outlook for 5-chloro-2,3-difluoronitrobenzene?
The market prospects of 5-% -2,3-diethylbenzene are promising. In today's world, this compound has its applications in many fields, so the demand for this compound is increasing.
The first research field is called the field, because of its characteristics, it may be used as an important medium for the synthesis of chemical compounds. The research method is not yet available, and the demand for compounds with specific properties and activities is increasing. 5-% -2,3-diethylbenzene or the synthesis of chemical compounds can provide an indispensable raw material for new research and development, which is expected to increase its demand step by step.
Furthermore, the field of materials also has its influence. It may be used in polymer materials with special properties, such as polymers with specific optical and chemical properties. The development of new and high-tech technologies such as electronics and optics is booming, and the demand for high-performance materials is not rising. 5-%-2,3-diacetylbenzene is a key factor in the synthesis of materials, and the market prospect is low.
In the field of chemical research, this compound is also a common substrate for companies to explore new anti-manufacturing and expand synthesis methods. In-depth research and expansion, it will increase its demand.
However, the market prospect is good, and it is also very challenging. Its synthesis process may need to be further refined to improve efficiency and reduce costs. If the cost is high, it will be limited in the market promotion. And the same replacement products or their market share will become powerful. Therefore, in order to find a favorable place in the market, producers need to not innovate their industries and improve their product performance. Therefore, the market of 5-%-2,3-diacetylbenzene has a bright future, but it also needs to be properly selected in order to enjoy the benefits of its market.
The first research field is called the field, because of its characteristics, it may be used as an important medium for the synthesis of chemical compounds. The research method is not yet available, and the demand for compounds with specific properties and activities is increasing. 5-% -2,3-diethylbenzene or the synthesis of chemical compounds can provide an indispensable raw material for new research and development, which is expected to increase its demand step by step.
Furthermore, the field of materials also has its influence. It may be used in polymer materials with special properties, such as polymers with specific optical and chemical properties. The development of new and high-tech technologies such as electronics and optics is booming, and the demand for high-performance materials is not rising. 5-%-2,3-diacetylbenzene is a key factor in the synthesis of materials, and the market prospect is low.
In the field of chemical research, this compound is also a common substrate for companies to explore new anti-manufacturing and expand synthesis methods. In-depth research and expansion, it will increase its demand.
However, the market prospect is good, and it is also very challenging. Its synthesis process may need to be further refined to improve efficiency and reduce costs. If the cost is high, it will be limited in the market promotion. And the same replacement products or their market share will become powerful. Therefore, in order to find a favorable place in the market, producers need to not innovate their industries and improve their product performance. Therefore, the market of 5-%-2,3-diacetylbenzene has a bright future, but it also needs to be properly selected in order to enjoy the benefits of its market.
What are the precautions for 5-chloro-2,3-difluoronitrobenzene during storage and transportation?
When storing and transporting 5-% deuterium-2,3-diethylheptyl ether, many matters need careful attention.
First, this material is chemically active and requires strict storage environment. It needs to be placed in a cool, dry and well-ventilated place, away from fire, heat and strong oxidants. Due to its active chemical properties, it may cause severe reactions in case of heat, open flame or strong oxidants, and even cause the risk of combustion and explosion. If stored in a high temperature environment, the molecular movement will intensify, the reactivity will increase greatly, and the risk factor will also soar.
Second, when transporting, the packaging must be tight. Choose suitable packaging materials to ensure that it can withstand certain pressure and vibration without leakage. Due to its volatility and toxicity, once it leaks, it will not only pollute the environment, but also endanger the health of transportation personnel and surrounding people. During transportation, it is also necessary to strictly control the temperature to avoid large fluctuations in temperature.
Third, storage and transportation personnel need to be professionally trained to be familiar with the characteristics and safety precautions of the substance. During operation, protective equipment such as gas masks, protective gloves and protective clothing should be worn in accordance with regulations to prevent contact and inhalation.
Fourth, regularly check the storage containers and transportation equipment. Check whether the containers are corroded, damaged, and whether the transportation pipelines are leaking. If any problems are found, they must be dealt with in time to prevent accidents. And the storage area and transportation tools should be equipped with corresponding emergency treatment equipment and fire fighting equipment to facilitate rapid response in emergency situations. In this way, the safety of 5-% deuterium-2,3-diethylheptyl ether during storage and transportation can be guaranteed to the greatest extent.
First, this material is chemically active and requires strict storage environment. It needs to be placed in a cool, dry and well-ventilated place, away from fire, heat and strong oxidants. Due to its active chemical properties, it may cause severe reactions in case of heat, open flame or strong oxidants, and even cause the risk of combustion and explosion. If stored in a high temperature environment, the molecular movement will intensify, the reactivity will increase greatly, and the risk factor will also soar.
Second, when transporting, the packaging must be tight. Choose suitable packaging materials to ensure that it can withstand certain pressure and vibration without leakage. Due to its volatility and toxicity, once it leaks, it will not only pollute the environment, but also endanger the health of transportation personnel and surrounding people. During transportation, it is also necessary to strictly control the temperature to avoid large fluctuations in temperature.
Third, storage and transportation personnel need to be professionally trained to be familiar with the characteristics and safety precautions of the substance. During operation, protective equipment such as gas masks, protective gloves and protective clothing should be worn in accordance with regulations to prevent contact and inhalation.
Fourth, regularly check the storage containers and transportation equipment. Check whether the containers are corroded, damaged, and whether the transportation pipelines are leaking. If any problems are found, they must be dealt with in time to prevent accidents. And the storage area and transportation tools should be equipped with corresponding emergency treatment equipment and fire fighting equipment to facilitate rapid response in emergency situations. In this way, the safety of 5-% deuterium-2,3-diethylheptyl ether during storage and transportation can be guaranteed to the greatest extent.
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