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5-Chloro-2,4-Difluorobenzenesulfonyl Chloride
Linshang Chemical
|
HS Code |
647238 |
| Chemical Formula | C6H2Cl2F2O2S |
| Molar Mass | 247.046 g/mol |
| Appearance | Typically a solid (appearance may vary depending on purity and conditions) |
| Physical State At Room Temperature | Solid |
| Solubility In Water | Likely insoluble (sulfonyl chlorides are often hydrolyzed in water) |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform |
| Vapor Pressure | Low (due to being a solid at room temperature, vapor pressure is relatively low) |
As an accredited 5-Chloro-2,4-Difluorobenzenesulfonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 5 - chloro - 2,4 - difluorobenzenesulfonyl Chloride: 100g in sealed, corrosion - resistant chemical container. |
| Storage | 5 - Chloro - 2,4 - difluorobenzenesulfonyl chloride should be stored in a cool, dry, and well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly - sealed container, preferably made of corrosion - resistant materials, to prevent leakage and exposure to moisture which could lead to decomposition or dangerous reactions. |
| Shipping | 5 - chloro - 2,4 - difluorobenzenesulfonyl chloride is a chemical. It should be shipped in tightly sealed, corrosion - resistant containers, following hazardous chemical shipping regulations to prevent leakage and ensure safety during transit. |
Competitive 5-Chloro-2,4-Difluorobenzenesulfonyl Chloride prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
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Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 5-Chloro-2,4-Difluorobenzenesulfonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 5-chloro-2, 4-difluorobenzenesulfonyl Chloride?
5-Chloro-2,4-difluorobenzenesulfonyl chloride is a crucial raw material in the field of organic synthesis and plays a key role in the preparation of many fine chemicals.
First, in the field of pharmaceutical synthesis, its role is quite significant. In the creation of many new drugs, 5-chloro-2,4-difluorobenzenesulfonyl chloride is often used as the starting material. After a series of delicate chemical reactions, such as condensation reactions with specific nitrogen-containing heterocyclic compounds, molecular structures with unique pharmacological activities can be constructed. Such structures or the treatment of specific diseases have shown excellent efficacy, such as in the process of anti-cancer drug research and development, the active ingredients that the substance participates in the construction, or can precisely act on specific targets of cancer cells to inhibit the growth and spread of cancer cells.
Second, in the field of pesticides, 5-chloro-2,4-difluorobenzenesulfonyl chloride also has extraordinary performance. With its special chemical structure, through clever synthesis and transformation, highly efficient pesticides, fungicides and other pesticide products can be prepared. For example, the pesticides derived from it may affect the nervous system of common crop pests and interfere with the normal physiological activities of pests, so as to achieve a good insecticidal effect, and the impact on the environment is relatively small, which is in line with the current needs of green agriculture development.
Furthermore, in the field of materials science, this compound also has applications. In the synthesis of some high-performance polymer materials, 5-chloro-2,4-difluorobenzenesulfonyl chloride can be introduced into the polymer backbone as a functional monomer. In this way, the polymer is endowed with special properties such as excellent heat resistance and chemical stability, expanding the application range of polymer materials in high-end fields such as aerospace, electronics and electrical appliances.
In summary, 5-chloro-2,4-difluorobenzenesulfonyl chloride has extensive and critical uses in many important fields such as medicine, pesticides, and materials science due to its unique chemical properties. It is of great significance to promote technological progress and development in various fields.
First, in the field of pharmaceutical synthesis, its role is quite significant. In the creation of many new drugs, 5-chloro-2,4-difluorobenzenesulfonyl chloride is often used as the starting material. After a series of delicate chemical reactions, such as condensation reactions with specific nitrogen-containing heterocyclic compounds, molecular structures with unique pharmacological activities can be constructed. Such structures or the treatment of specific diseases have shown excellent efficacy, such as in the process of anti-cancer drug research and development, the active ingredients that the substance participates in the construction, or can precisely act on specific targets of cancer cells to inhibit the growth and spread of cancer cells.
Second, in the field of pesticides, 5-chloro-2,4-difluorobenzenesulfonyl chloride also has extraordinary performance. With its special chemical structure, through clever synthesis and transformation, highly efficient pesticides, fungicides and other pesticide products can be prepared. For example, the pesticides derived from it may affect the nervous system of common crop pests and interfere with the normal physiological activities of pests, so as to achieve a good insecticidal effect, and the impact on the environment is relatively small, which is in line with the current needs of green agriculture development.
Furthermore, in the field of materials science, this compound also has applications. In the synthesis of some high-performance polymer materials, 5-chloro-2,4-difluorobenzenesulfonyl chloride can be introduced into the polymer backbone as a functional monomer. In this way, the polymer is endowed with special properties such as excellent heat resistance and chemical stability, expanding the application range of polymer materials in high-end fields such as aerospace, electronics and electrical appliances.
In summary, 5-chloro-2,4-difluorobenzenesulfonyl chloride has extensive and critical uses in many important fields such as medicine, pesticides, and materials science due to its unique chemical properties. It is of great significance to promote technological progress and development in various fields.
What are the physical properties of 5-chloro-2, 4-difluorobenzenesulfonyl Chloride
5-Chloro-2,4-difluorobenzenesulfonyl chloride, an important compound in organic chemistry. Its physical properties are crucial, and it is related to many chemical processes and practical applications.
From its appearance, it usually appears as a colorless to pale yellow liquid. This color characteristic may assist chemists to infer its purity and reaction state during preliminary observations. Its texture is relatively dense, and its flow is slightly inferior to that of common light solvents. Its relatively slow flow can be observed in containers.
On odor, 5-chloro-2,4-difluorobenzenesulfonyl chloride emits a pungent and corrosive odor. This odor is unique and easy to be captured by a keen sense of smell. It also warns users to pay special attention when exposed, because it may irritate the respiratory tract and mucosa.
In terms of boiling point, the boiling point of this compound is in a specific range. The value of boiling point is of great significance for the control of its separation, purification and reaction conditions. When the temperature rises to the boiling point, 5-chloro-2,4-difluorobenzenesulfonyl chloride will change from liquid to gaseous state, and can be separated from other substances with different boiling points by means of distillation.
Melting point is also an important physical property. Its melting point is specific. When the temperature drops below the melting point, 5-chloro-2,4-difluorobenzenesulfonyl chloride will solidify into a solid state. This property needs to be taken into account during storage and transportation, and the appropriate temperature can ensure that it is in the desired physical state.
In terms of solubility, 5-chloro-2,4-difluorobenzenesulfonyl chloride has a certain solubility in some organic solvents, such as common ether, dichloromethane, etc. However, its solubility in water is poor, and it is easy to chemically react in water or cause decomposition. This difference in solubility provides a basis for the choice of reaction medium in organic synthesis.
Density is also a physical property that cannot be ignored. The density of 5-chloro-2,4-difluorobenzenesulfonyl chloride is higher than that of water, and this property affects the distribution and separation of substances in reaction systems involving operations such as stratification.
From its appearance, it usually appears as a colorless to pale yellow liquid. This color characteristic may assist chemists to infer its purity and reaction state during preliminary observations. Its texture is relatively dense, and its flow is slightly inferior to that of common light solvents. Its relatively slow flow can be observed in containers.
On odor, 5-chloro-2,4-difluorobenzenesulfonyl chloride emits a pungent and corrosive odor. This odor is unique and easy to be captured by a keen sense of smell. It also warns users to pay special attention when exposed, because it may irritate the respiratory tract and mucosa.
In terms of boiling point, the boiling point of this compound is in a specific range. The value of boiling point is of great significance for the control of its separation, purification and reaction conditions. When the temperature rises to the boiling point, 5-chloro-2,4-difluorobenzenesulfonyl chloride will change from liquid to gaseous state, and can be separated from other substances with different boiling points by means of distillation.
Melting point is also an important physical property. Its melting point is specific. When the temperature drops below the melting point, 5-chloro-2,4-difluorobenzenesulfonyl chloride will solidify into a solid state. This property needs to be taken into account during storage and transportation, and the appropriate temperature can ensure that it is in the desired physical state.
In terms of solubility, 5-chloro-2,4-difluorobenzenesulfonyl chloride has a certain solubility in some organic solvents, such as common ether, dichloromethane, etc. However, its solubility in water is poor, and it is easy to chemically react in water or cause decomposition. This difference in solubility provides a basis for the choice of reaction medium in organic synthesis.
Density is also a physical property that cannot be ignored. The density of 5-chloro-2,4-difluorobenzenesulfonyl chloride is higher than that of water, and this property affects the distribution and separation of substances in reaction systems involving operations such as stratification.
What is the synthesis method of 5-chloro-2, 4-difluorobenzenesulfonyl Chloride
The synthesis of 5-chloro-2,4-difluorobenzenesulfonyl chloride is an important topic in the field of organic synthesis. To obtain this compound, the following methods are often followed.
First, a suitable halogenating agent is used to halogenate the benzene ring at a specific position under appropriate reaction conditions. If chlorine atoms and fluorine atoms are introduced by chlorine sources and fluorine sources, respectively, the reaction temperature, reaction time and proportion of reactants should be paid attention to in this step. The choice of halogenating agent is very critical, and its activity and selectivity affect the position and efficiency of halogen atoms introduced.
Next, the sulfonyl group is introduced into the benzene ring through a sulfonation reaction. Usually, fuming sulfuric acid or chlorosulfonic acid are used as sulfonating reagents, and the benzene ring is sulfonated at a suitable In this process, the precise control of the reaction conditions is related to the sulfonation position and the purity of the product.
At the end, a chlorination reagent is used to convert the sulfonyl group into a sulfonyl chloride group. Commonly used chlorination reagents such as phosphorus pentachloride, thionyl chloride, etc. When phosphorus pentachloride is used, the reactivity is high, but the post-treatment is slightly more complex; thionyl chloride is relatively mild, and the by-products are gases, which are easy to separate.
The whole process of synthesis requires separation and purification after each step of the reaction, such as extraction, distillation, recrystallization, etc., to remove impurities and obtain pure 5-chloro-2,4-difluorobenzenesulfonyl chloride. The reaction conditions and reagent selection vary according to laboratory conditions, cost considerations, and product requirements, and must be carefully optimized to obtain this target compound efficiently.
First, a suitable halogenating agent is used to halogenate the benzene ring at a specific position under appropriate reaction conditions. If chlorine atoms and fluorine atoms are introduced by chlorine sources and fluorine sources, respectively, the reaction temperature, reaction time and proportion of reactants should be paid attention to in this step. The choice of halogenating agent is very critical, and its activity and selectivity affect the position and efficiency of halogen atoms introduced.
Next, the sulfonyl group is introduced into the benzene ring through a sulfonation reaction. Usually, fuming sulfuric acid or chlorosulfonic acid are used as sulfonating reagents, and the benzene ring is sulfonated at a suitable In this process, the precise control of the reaction conditions is related to the sulfonation position and the purity of the product.
At the end, a chlorination reagent is used to convert the sulfonyl group into a sulfonyl chloride group. Commonly used chlorination reagents such as phosphorus pentachloride, thionyl chloride, etc. When phosphorus pentachloride is used, the reactivity is high, but the post-treatment is slightly more complex; thionyl chloride is relatively mild, and the by-products are gases, which are easy to separate.
The whole process of synthesis requires separation and purification after each step of the reaction, such as extraction, distillation, recrystallization, etc., to remove impurities and obtain pure 5-chloro-2,4-difluorobenzenesulfonyl chloride. The reaction conditions and reagent selection vary according to laboratory conditions, cost considerations, and product requirements, and must be carefully optimized to obtain this target compound efficiently.
Precautions for storage and transportation of 5-chloro-2, 4-difluorobenzenesulfonyl Chloride
5-Chloro-2,4-difluorobenzenesulfonyl chloride is a chemical substance. When storing and transporting, the following things should be paid more attention to:
First, the storage environment must be cool and dry. This substance is easily affected by humid gas and causes it to deteriorate, so it should be stored in a dry place, away from water sources and humid places. A cool environment can reduce the rate of chemical reactions and maintain the stability of its chemical properties. If placed in a high temperature place, or cause adverse reactions such as decomposition, it will damage its quality.
Second, it needs to be tightly sealed. 5-Chloro-2,4-difluorobenzenesulfonyl chloride or react with components in the air, such as oxygen, water vapor, etc., and the seal can prevent it from contacting with external substances. Use a suitable sealed container, such as a glass bottle with a sealed bottle cap, or a special sealed plastic container, to ensure that no gas or liquid can enter or exit.
Third, when storing and transporting, do not mix or mix with alkalis, alcohols and other substances. 5-Chloro-2,4-difluorobenzenesulfonyl chloride has active chemical properties. It is easy to neutralize when it encounters alkalis. When it encounters alcohols, it may also react with substitution, which not only destroys its own structure, but also causes dangerous conditions, such as heat generation and explosion.
Fourth, during transportation, protective measures are indispensable. Make sure that the container is stable and will not collide or tip over. Use shock-proof and drop-proof packaging materials, such as foam, sponge, etc. to surround the container. And the transporter should be familiar with its characteristics and emergency treatment methods. In case of leakage, it can be disposed of quickly and properly.
Fifth, the storage place should be clearly marked. Mark the name "5-chloro-2,4-difluorobenzenesulfonyl chloride", as well as its dangerous characteristics, such as "corrosive" and "irritant". In this way, personnel will know the danger at first sight, and they can be extra cautious when handling and handling.
First, the storage environment must be cool and dry. This substance is easily affected by humid gas and causes it to deteriorate, so it should be stored in a dry place, away from water sources and humid places. A cool environment can reduce the rate of chemical reactions and maintain the stability of its chemical properties. If placed in a high temperature place, or cause adverse reactions such as decomposition, it will damage its quality.
Second, it needs to be tightly sealed. 5-Chloro-2,4-difluorobenzenesulfonyl chloride or react with components in the air, such as oxygen, water vapor, etc., and the seal can prevent it from contacting with external substances. Use a suitable sealed container, such as a glass bottle with a sealed bottle cap, or a special sealed plastic container, to ensure that no gas or liquid can enter or exit.
Third, when storing and transporting, do not mix or mix with alkalis, alcohols and other substances. 5-Chloro-2,4-difluorobenzenesulfonyl chloride has active chemical properties. It is easy to neutralize when it encounters alkalis. When it encounters alcohols, it may also react with substitution, which not only destroys its own structure, but also causes dangerous conditions, such as heat generation and explosion.
Fourth, during transportation, protective measures are indispensable. Make sure that the container is stable and will not collide or tip over. Use shock-proof and drop-proof packaging materials, such as foam, sponge, etc. to surround the container. And the transporter should be familiar with its characteristics and emergency treatment methods. In case of leakage, it can be disposed of quickly and properly.
Fifth, the storage place should be clearly marked. Mark the name "5-chloro-2,4-difluorobenzenesulfonyl chloride", as well as its dangerous characteristics, such as "corrosive" and "irritant". In this way, personnel will know the danger at first sight, and they can be extra cautious when handling and handling.
What is the market price range for 5-chloro-2, 4-difluorobenzenesulfonyl Chloride?
5-Chloro-2,4-difluorobenzenesulfonyl chloride, this product is in the market, and its price range is difficult to determine. Its price often changes for many reasons.
First, the price of raw materials has a great impact. If the price of chlorine, fluorine and other raw materials required for the synthesis of this compound rises and falls, the price of 5-chloro-2,4-difluorobenzenesulfonyl chloride also fluctuates. If the source of chlorine, or due to the difficulty of preparation and the abundance of the origin, the price fluctuates, which in turn causes the cost of this product to change, and the market price also varies.
Second, the method of preparation is related to cost and output, and also affects its price. Sophisticated methods can increase output and reduce consumption, and the price may be stable and appropriate; if the method is not good, the output is less and the consumption is more, the price will be higher.
Third, the supply and demand of the city is the main reason. If many companies need this compound to produce other things, and the demand exceeds the supply, the price will rise; conversely, if the supply exceeds the demand, the merchant will sell their goods, and the price may drop.
Fourth, the change of the current situation also has an impact. If the decree concerns the chemical industry, or the production is limited, the supply is small and the price rises; or if the state of trade, the increase or decrease of taxes, and the obstruction of transportation can all make the price different.
In summary, it is not easy to determine the range of the inter-market price of 5-chloro-2,4-difluorobenzenesulfonyl chloride. It is necessary to study all the factors in detail before we can get a rough idea. Or at different times and in different places, the price ranges from tens of yuan per kilogram to hundreds of yuan per kilogram, but this is only an approximate number and is not an exact value.
First, the price of raw materials has a great impact. If the price of chlorine, fluorine and other raw materials required for the synthesis of this compound rises and falls, the price of 5-chloro-2,4-difluorobenzenesulfonyl chloride also fluctuates. If the source of chlorine, or due to the difficulty of preparation and the abundance of the origin, the price fluctuates, which in turn causes the cost of this product to change, and the market price also varies.
Second, the method of preparation is related to cost and output, and also affects its price. Sophisticated methods can increase output and reduce consumption, and the price may be stable and appropriate; if the method is not good, the output is less and the consumption is more, the price will be higher.
Third, the supply and demand of the city is the main reason. If many companies need this compound to produce other things, and the demand exceeds the supply, the price will rise; conversely, if the supply exceeds the demand, the merchant will sell their goods, and the price may drop.
Fourth, the change of the current situation also has an impact. If the decree concerns the chemical industry, or the production is limited, the supply is small and the price rises; or if the state of trade, the increase or decrease of taxes, and the obstruction of transportation can all make the price different.
In summary, it is not easy to determine the range of the inter-market price of 5-chloro-2,4-difluorobenzenesulfonyl chloride. It is necessary to study all the factors in detail before we can get a rough idea. Or at different times and in different places, the price ranges from tens of yuan per kilogram to hundreds of yuan per kilogram, but this is only an approximate number and is not an exact value.
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