5-Chloro-2-Methoxy-Benzeneboronic Acid

Linshang Chemical

Specifications

HS Code

242587

Chemical Formula C7H8BO4Cl
Molar Mass 202.401 g/mol
Appearance Solid
Melting Point 140 - 145 °C
Boiling Point N/A
Solubility In Water Slightly soluble
Solubility In Organic Solvents Soluble in some organic solvents like dichloromethane
Pka N/A
Density N/A
Stability Stable under normal conditions, avoid strong oxidizing agents

As an accredited 5-Chloro-2-Methoxy-Benzeneboronic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 5 - chloro - 2 - methoxy - benzeneboronic Acid: 100g in a sealed, chemical - resistant bottle.
Storage 5 - Chloro - 2 - methoxy - benzeneboronic acid should be stored in a cool, dry place. Keep it away from heat sources, direct sunlight, and moisture. Store in a tightly - sealed container to prevent exposure to air, which could potentially lead to oxidation or hydrolysis. Ideal storage is in a chemical cabinet, separated from incompatible substances to ensure safety.
Shipping 5 - chloro - 2 - methoxy - benzeneboronic Acid is shipped in well - sealed containers. Precautions are taken for its chemical nature, ensuring it's protected from moisture, heat, and shock during transit in compliance with chemical shipping regulations.
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5-Chloro-2-Methoxy-Benzeneboronic Acid 5-Chloro-2-Methoxy-Benzeneboronic Acid
General Information
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Frequently Asked Questions

As a leading 5-Chloro-2-Methoxy-Benzeneboronic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 5-chloro-2-methoxyphenylboronic acid?
5-Bromo-2-methoxybenzaldehyde is one of the organic compounds. It has unique properties and is very important in many chemical reactions and synthesis fields.
The appearance of this compound is often solid, mostly white to light yellow crystalline powder. Its melting and boiling point characteristics have a specific range due to the interaction of bromine atoms, methoxy groups and aldehyde groups in the molecular structure. The melting point is about a certain value, and the boiling point is also defined accordingly. This characteristic helps to realize the separation and purification of 5-bromo-2-methoxybenzaldehyde by temperature regulation in chemical production and experimental operations.
The solubility of 5-bromo-2-methoxybenzaldehyde is unique. It shows a certain solubility in common organic solvents such as ethanol, ethyl ether, and dichloromethane, but it has little solubility in water. This difference in solubility makes it possible to select suitable solvents to achieve specific reactions or separation purposes according to different needs in the chemical synthesis process.
In terms of chemical activity, the presence of aldehyde groups gives it significant reactivity. It can participate in many classical organic reactions, such as nucleophilic addition reactions with nucleophiles. The polarity of the carbon-oxygen double bond in the aldehyde group makes the carbon atom electrophilic and vulnerable to attack by nucleophilic reagents. Under specific conditions, it can form acetals with alcohols. This reaction is often used in organic synthesis to protect the aldehyde group, and then reduce the aldehyde group when the time is right.
Furthermore, the bromine atom and methoxy group on the benzene ring have a great influence on the electron cloud density and reactivity of the benzene ring. Although the bromine atom has an electron-absorbing induction effect, its lone pair electrons are conjugated with the benzene ring, resulting in relatively high electron cloud densities of its adjacent and para-sites, which makes the electrophilic substitution reaction easier to occur in the adjacent and para-sites of the bromine atom. Methoxy group is the power supplier group, which enhances the electron cloud density of the benzene ring and further affects the reactivity and selectivity.
5-Bromo-2-methoxybenzaldehyde is widely used in medicine, pesticides, materials and other fields due to its unique chemical properties. In pharmaceutical synthesis, it is often used as a key intermediate to build complex drug molecular structures through a series of reactions to assist in the development of new drugs; in the field of pesticides, it can be used to synthesize pesticide ingredients with specific biological activities to improve pesticide performance; in the field of materials science, it can participate in functional material synthesis, endowing materials with special optical, electrical and other properties.
What are the common uses of 5-chloro-2-methoxyphenylboronic acid?
The common uses of 5-hydroxy- 2-methylaminobenzoic acid can be found in "Tiangong Kaiwu". This compound is quite effective in the art of dyeing and weaving. It can be used as a dye aid to help dyes better adhere to fabrics, making the color bright and lasting. Ancient dyers often use this material to adjust dye formulas, making the fabric color as gorgeous as the morning sun and lasting for a long time.
In the pharmaceutical industry, there are also traces. It can provide key intermediates for drug synthesis, help doctors make good medicines, and cure various diseases. Ancient physicians, after repeated trials, observed its characteristics, used to prepare pill powder, relieve pain, and save people from sinking diseases.
In the field of chemical analysis, it is also a powerful assistant. It can be used as an indicator to accurately measure the pH of the solution, so that the experimental results are accurate. In the past, chemists used this substance as a guide to explore the mysteries of chemistry and the characteristics of analytes.
It can also add luster to the preparation of fragrances. Its unique chemical structure can add a unique flavor to the fragrance and make the aroma rich. According to its characteristics, perfumers skillfully prepare to make an elegant and charming fragrance, adding a rich fragrance to life.
In summary, 5-hydroxy- 2-methylaminobenzoic acid has a wide range of uses and is of great value in the fields of dyeing and weaving, pharmaceuticals, analysis, fragrances, etc. It has contributed a lot to the development of technology and science throughout the ages.
What are the synthesis methods of 5-chloro-2-methoxyphenylboronic acid?
To prepare 5-bromo-2-methoxybenzoic acid, there are various methods. First, it can be obtained by starting with 2-methoxybenzoic acid and brominating it. First, take 2-methoxybenzoic acid and place it in a suitable reaction bottle, dissolve it with an appropriate amount of solvent, such as glacial acetic acid. Then slowly add brominating reagents, such as bromine, and can be accompanied by catalysts, such as iron powder or iron tribromide. The reaction requires temperature control, usually at room temperature or slightly higher temperatures, so that bromine atoms selectively replace hydrogen atoms at specific positions on the benzene ring to obtain 5-bromo-2-methoxybenzoic acid. In this process, the choice of solvent is very important, and its polarity and solubility all affect the rate and selectivity of the reaction; the amount of catalyst also needs to be precisely controlled, and too much or too little may cause side reactions to increase.
Second, you can start with 2-methoxybenzaldehyde. First, 2-methoxybenzaldehyde is reacted with bromine under suitable conditions, so that bromine is substituted in the appropriate position of the benzene ring to obtain bromine-containing benzaldehyde derivatives. Then, the aldehyde group is converted into a carboxyl group through an oxidation step. The oxidation method can be carried out in an alkaline environment with a strong oxidant, such as potassium permanganate, and then acidified to obtain 5-bromo-2-methoxybenzoic acid. This approach requires attention to the control of the conditions of the oxidation step. If the amount of strong oxidizing agent and the reaction temperature are not appropriate, it is easy to cause side reactions such as excessive oxidation, which will affect the purity and yield of the product.
Third, 2-methoxyaniline is used as the raw material. First, 2-methoxyaniline is reacted by diazotization to obtain diazonium salt. Then the diazonium salt is reacted with reagents such as cuprous bromide to realize the substitution of bromine atoms for amino groups to obtain bromine-containing anisole derivatives. Subsequently, the substituent on the benzene ring is converted into a carboxyl group through a specific reaction, such as reacting with Grignard's reagent, then reacting with carbon dioxide, and finally acidifying to obtain the target product 5-bromo-2-methoxybenzoic acid. This route is a bit complicated, and each step of the reaction requires strict control of conditions. The temperature and reagent ratio of the diazotization reaction are all related to the generation of the final product.
What are the precautions for 5-chloro-2-methoxyphenylboronic acid in storage and transportation?
5-% -2-methylbenzenesulfonic acid should be stored in the warehouse, so pay attention to the general situation. This property may be affected by external factors, so be careful.
The place where it is hidden, the first important environment. It is appropriate to store it in a dry, dry and well-connected place. If it is in a humid place, it is easy to get damp, causing its chemical properties to be changed, and its effectiveness may be improved. In case of high temperature, this compound may be at risk of biodegradation and degradation. The degree of resistance should be controlled in a specific area to ensure its performance.
Furthermore, light also needs to be prevented. Direct light exposure, or the introduction of chemical reactions, and the object. Therefore, it is appropriate to store in a shading device, such as a brown bottle, which can block light and reduce its chemical properties.
It is necessary to ensure the safety of the product. It is necessary to use suitable materials to ensure its confidentiality and prevent leakage. If this object is released on the way, it will not damage its own products, or endanger the surrounding environment and people. The containers used are shock-resistant and anti-collision, so as not to be damaged by bumps.
In addition, the isolation of other objects should also be removed. This compound or some substances are caused by reaction, so it is not hidden, and the non-oxidizing and original substances can be combined to prevent accidental transformation.
In addition, 5-% -2-methylbenzenesulfonic acid is stored in the environment, light, packaging, and other materials, all of which should be carefully paid attention to in order to ensure the safety of its products.
What is the market price range of 5-chloro-2-methoxyphenylboronic acid?
5-% -2-methylbenzoic acid, which may be a commonly used material or chemical raw material for non-conventional products, is clearly stated in the market. However, the raw materials required for its synthesis, the degree of engineering, and the similar compounds required for its synthesis can be slightly estimated.
, methyl and other groups are introduced into benzoic acid. If the synthesis step is to proliferate, special reaction parts or catalysts are required, and the cost will increase, and the price will also be higher. If the synthesis phase is not easy, and the supply of raw materials is sufficient, the grid or phase will be easy.
However, because I do not know its use and the amount of demand in the market, we can determine its cutting price. For example, if it is used in special research and development, due to high degree requirements, large production capacity, and limited market demand, the price is often not cheap; if it is used in general chemical industry, and the production technology is mature, the supply volume is large, and the price is low or low.
And the quality of chemical products is affected by many factors, such as raw materials, policy laws, and the shape of the city. In order to know the market of 5-%-2-methylbenzoic acid, it is appropriate to test the latest price of chemical raw materials trading platforms, or to learn from chemical manufacturers and production enterprises.