5-Chloro-2-Methylbenzenethiol
Linshang Chemical
HS Code |
966229 |
Chemical Formula | C7H7ClS |
Molar Mass | 158.65 g/mol |
Appearance | Typically a liquid (physical state may vary based on conditions) |
Boiling Point | Data may vary, but generally in a certain range related to its molecular structure |
Melting Point | Specific value related to its intermolecular forces |
Density | A value indicating mass per unit volume |
Solubility In Water | Low solubility due to non - polar benzene ring |
Solubility In Organic Solvents | Good solubility in many organic solvents like ethanol, acetone |
Odor | Characteristic sulfur - containing, pungent odor |
Flash Point | A value related to its flammability |
As an accredited 5-Chloro-2-Methylbenzenethiol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 100g of 5 - chloro - 2 - methylbenzenethiol packaged in a sealed, chemical - resistant bottle. |
Storage | 5 - chloro - 2 - methylbenzenethiol should be stored in a cool, well - ventilated area, away from heat and ignition sources due to its potential flammability. Keep it in a tightly closed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents and incompatible substances to prevent chemical reactions. Ensure the storage area has proper spill - containment measures. |
Shipping | 5 - chloro - 2 - methylbenzenethiol is a chemical. For shipping, it must be in proper, leak - proof containers. Label it clearly as a chemical, follow regulations for hazardous substances transport to ensure safe and compliant delivery. |
Competitive 5-Chloro-2-Methylbenzenethiol prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading 5-Chloro-2-Methylbenzenethiol supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
In the field of medicinal chemistry, some compounds synthesized with the help of 5-chloro-2-methylthiophenol may have specific biological activities. For example, by adjusting its molecular structure, new drug lead compounds with antibacterial, anti-inflammatory or anti-tumor activities can be searched. Researchers can use it to build different chemical skeletons, and then conduct biological activity screening for the synthesized derivatives, hoping to find substances with potential medicinal value.
In materials science, 5-chloro-2-methylthiophenol can also play an important role. For example, when preparing certain functional materials, it can be introduced into the molecular structure of the material as one of the raw materials. Due to the unique chemical properties of thiophenol groups, it may endow the material with special electrical, optical or mechanical properties. For example, when synthesizing conductive polymers or photochromic materials, the clever use of 5-chloro-2-methylthiophenol may improve the properties of materials and meet the needs of special properties of materials in different scenarios.
Furthermore, in the preparation of fine chemical products, 5-chloro-2-methylthiophenol also has applications. It can be used to produce some special additives, catalysts or additives. These fine chemical products can be used to improve the properties of other products, such as adding additives to certain coatings, plastics or rubber products, which can improve the stability, wear resistance or processing performance of the product.
Looking at its appearance, under room temperature and pressure, 5-chloro-2-methylthiophenol is mostly colorless to light yellow liquid, and its color is like the first light of the morning, giving people a soft feeling.
Smell its smell, it exudes a rather pungent and special thiol smell. This smell is like the smell of sulfur mixed with some irritating substances. It is rich and highly recognizable, and it is diffuse in the air, which is difficult to ignore.
When it comes to melting point, this compound has a low melting point and is in the relatively low temperature range, just like thin ice in winter, which is easy to melt when heated.
In terms of boiling point, its boiling point is in a certain temperature range, and it needs to be properly heated to make it boil, just like heating a pot of water to a specific temperature, the water will boil and tumble.
Solubility is also one of its important physical properties. 5-Chloro-2-methylthiophenol exhibits good solubility in organic solvents, such as common ethanol and ether, etc., and can be uniformly mixed with fish. However, in water, its solubility is poor, and the two are like oil and water, which are difficult to melt.
Above the density, it is moderate in density compared with common organic solvents, neither frivolous nor heavy, and has a specific position in the liquid system.
In addition, the vapor pressure of 5-chloro-2-methylthiophenol varies at different temperatures. When the temperature increases, the vapor pressure increases, just like heating water in a pot. The higher the temperature, the easier the water vapor will rise.
Its refractive index is also a specific value. When light passes through, it will be refracted according to this specific refractive index, presenting a unique optical phenomenon.
In summary, the physical properties of 5-chloro-2-methylthiophenol are rich and diverse, and each property is interrelated, which constitutes its unique physical properties and provides an important basis for research and application in related fields.
Looking at its chemical activity, mercaptan is the key activity checking point of this compound. Because the sulfur atom has lone pairs of electrons, 5-chloro-2-methylbenzene mercaptan is very easy to participate in nucleophilic reactions. For example, it can undergo nucleophilic substitution reactions with halogenated hydrocarbons. The sulfur atom of the mercaptan group nucleophilically attacks the carbon atom of the halogenated hydrocarbons, and the halogen ions leave to form new sulfur-containing organic compounds. This reaction is of great significance in the formation of carbon-sulfur bonds and is often used in the synthesis of many drugs and fine chemicals.
Furthermore, the acidity of 5-chloro-2-methylbenzene mercaptan is also worthy of attention. Compared with alcohols, mercaptan is slightly more acidic. Because the radius of the sulfur atom is larger than that of the oxygen atom, the bond energy of the S-H bond is smaller than that of the O-H bond, and the hydrogen ion is more likely to leave. In an alkaline environment, 5-chloro-2-methylbenzene mercaptan can react with bases to form corresponding mercaptan salts. This mercaptan can be used as a nucleophile in organic synthesis and participate in more complex reactions.
In addition, the chlorine atoms in 5-chloro-2-methylbenzene mercaptan also have certain reactivity. Although the nucleophilic substitution activity of chlorine atoms on benzene rings is lower than that of aliphatic hydrocarbon halides, under certain conditions, such as high temperature, strong bases or the presence of catalysts, chlorine atoms can be replaced by other nucleophilic reagents, thus modifying benzene rings, introducing different functional groups, expanding the structural diversity of compounds, and providing more possibilities for organic synthesis. Due to the presence of thiol groups and chlorine atoms, 5-chloro-2-methylbenzene mercaptan exhibits various chemical properties and plays an important role in the stage of organic synthetic chemistry, providing a rich reaction path and foundation for the creation of various organic compounds.
In ancient chemical preparation, it often started with natural materials. If this product is made, natural materials containing benzene ring, chlorine and methyl can be found as raw materials. Although there is no modern fine separation technology in ancient times, it can be enriched by simple physical methods such as distillation and extraction.
Or it can be started from sulfur-containing ores. In ancient times, it was known about the characteristics of sulfur ores and was often treated by roasting. The sulfur-containing ore is co-roasted with specific benzene ring and chlorine and methyl-containing raw materials. At high temperature, the sulfur and the raw materials chemically interact, or sulfur-containing aromatic compounds can be formed. At this time, the roasting temperature and time need to be controlled. If the temperature is high, the raw materials may decompose; if it is low, the reaction is difficult to be sufficient.
Furthermore, fermentation methods can be used. The ancient fermentation process is mature, and specific microorganisms act on organic matter containing suitable groups. After microbial metabolism, the target product may be formed. This process needs to be adapted to microorganisms and control the fermentation environment, such as temperature, pH, oxygen amount, etc. If the temperature is not suitable, the microbial activity is suppressed; acid-base imbalance, fermentation direction or bias.
Or prepared by displacement reaction. The principle of substitution has been known in ancient chemistry. 5-chloro-2-methylthiophenol is obtained by reacting sulfur-containing compounds with halogenates containing benzene ring, chlorine, and methyl. However, it is necessary to find active and suitable reactants and suitable catalysts to promote the reaction.
Although the ancient process lacks modern precision and efficiency, its ideas and methods lay the foundation for today's chemical preparation. After improvement and refinement, it can provide ideas for the preparation of 5-chloro-2-methylthiophenol.
First safety protection. This compound may be irritating and toxic, touch the human body or cause discomfort, or even endanger health. When storing, ensure that the storage area is well ventilated, and personnel should be equipped with appropriate protective equipment, such as protective gloves, goggles, gas masks, etc., to prevent skin contact, inhalation or accidental ingestion.
Times and storage conditions. It should be placed in a cool, dry and well ventilated place, away from fire and heat sources, to prevent fire or chemical reactions. Because it is sensitive to light or heat, it should be stored away from light, and it should be stored separately from oxidants, acids, etc., and must not be mixed to avoid dangerous reactions.
In terms of transportation, it is also necessary to strictly abide by the norms. It must be implemented in accordance with relevant regulations on the transportation of hazardous chemicals, and use packaging materials that meet the requirements to ensure that the packaging is tight and prevent leakage. During transportation, drivers and escorts must be familiar with its characteristics and emergency treatment methods, and pay close attention to the status of transportation tools to ensure smooth transportation and avoid severe vibration and impact.
In addition, whether it is storage or transportation, it is necessary to have a perfect emergency treatment plan. In the event of a leak, the surrounding personnel should be evacuated quickly to isolate the leakage area. Emergency responders need to wear professional protective equipment and take corresponding measures according to the leakage situation, such as absorbing with inert materials such as sand and vermiculite, or neutralizing with suitable chemical reagents. In short, the storage and transportation of 5-chloro-2-methylthiophenol is essential, and all details cannot be ignored, so as to ensure the safety of personnel and the environment are not endangered.

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