5-Chloro-3-Fluoro-2-Methoxynitrobenzene
Linshang Chemical
HS Code |
762209 |
Chemical Formula | C7H5ClFNO3 |
Molecular Weight | 207.57 |
Appearance | Typically a solid (description may vary based on purity and conditions) |
Melting Point | Data may vary, needs specific experimental determination |
Boiling Point | Data may vary, needs specific experimental determination |
Solubility In Water | Low solubility in water (organic nitro - halide compounds generally have poor water solubility) |
Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform, etc. |
Density | Data may vary, needs specific experimental determination |
Flash Point | Data may vary, needs specific experimental determination |
Vapor Pressure | Low vapor pressure at room temperature (as a solid, vapor pressure is relatively low compared to volatile liquids) |
As an accredited 5-Chloro-3-Fluoro-2-Methoxynitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 1 kg of 5 - chloro - 3 - fluoro - 2 - methoxynitrobenzene packaged in airtight containers. |
Storage | 5 - Chloro - 3 - fluoro - 2 - methoxynitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and strong oxidizing agents. Store in a tightly sealed container to prevent moisture and air exposure, which could potentially lead to degradation. Label the storage container clearly to avoid mix - ups. |
Shipping | 5 - Chloro - 3 - fluoro - 2 - methoxynitrobenzene is shipped in tightly sealed, corrosion - resistant containers. It's transported with proper labeling indicating its hazardous nature, following strict regulations for chemical shipments to ensure safety. |
Competitive 5-Chloro-3-Fluoro-2-Methoxynitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.
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As a leading 5-Chloro-3-Fluoro-2-Methoxynitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
In the field of medicinal chemistry, it can be used as a key intermediate for the synthesis of various biologically active compounds. For example, it can be linked with other molecules containing active functional groups by means of specific chemical reactions to build a complex molecular skeleton of drugs. Due to its unique chemical structure, the bromine atom, alkenyl, methoxycarbonyl, and benzyl ether structures can all participate in diverse chemical reactions, thereby introducing specific chemical properties and spatial configurations to drug molecules, or enhancing the ability of drugs to bind to targets, or improving the pharmacokinetic properties of drugs, such as improving the solubility, stability, and bioavailability of drugs, helping to develop more efficient and safe new drugs.
In the field of materials science, 5-bromo-3-ene-2-methoxycarbonyl benzyl ethers also have significant uses. Its alkenyl reactivity can be used to introduce them into the structure of polymer materials through polymerization. In this way, the synthesized polymer material can exhibit unique physical and chemical properties due to the introduction of this special structural unit, such as improving the optical, electrical or mechanical properties of the material. For example, if it is applied to the preparation of optical materials, it may endow the material with specific refractive index, fluorescence properties, etc., to meet the special needs of different fields such as optical lenses and optoelectronic devices for the optical properties of the material.
In addition, in the study of organic synthesis methodology, this compound is often used as a model substrate to explore novel chemical reaction pathways and synthesis strategies. Chemists can use the selective reactions of different functional groups in their structures to develop more efficient, green, and atom-economical synthesis methods, promoting the further development of organic synthetic chemistry and providing new ideas and methods for the synthesis of more complex organic compounds.
The ancient chemical process depends on the accumulation of practice, and uses natural materials as the basis to promote its change by various means. To make this compound, you can first take natural products containing alkenyl and benzyl structures, such as some alkenyl plant essential oils and benzyl-related alkaloids. However, the structure of natural products is complex and needs to be purified and transformed.
First, bromine atoms can be introduced by halogenation. In ancient times, natural minerals of halogen elements, such as halite, were co-located with alkenyl compounds, supplemented by appropriate temperatures and catalysts. Ancient catalysts may be some metal salts, such as copper salts and iron salts, by virtue of their variable valence properties, promote the addition of bromine and alkenyl bonds, so that the bromine atom just falls in the 5-position.
Second, introduce methoxy carbonyl. Ancient or find natural esters containing methoxy and carbonyl, such as methyl formate. First, the benzyl ether structure is activated with a strong base, such as potassium carbonate in plant ash, and then it is co-heated with methyl formate to carry out nucleophilic substitution, so that the methoxy carbonyl is attached to the 2-position.
Third, construct a 3-ene structure. For raw materials containing alkenyl groups, the position of the double bond can be adjusted by oxidation and dehydrogenation. Ancient oxidation, or use air, some metal oxides, such as manganese dioxide. Under suitable conditions, rearrange and dehydrogenate the alkenyl structure to form a 3-ene structure.
When operating, check the proportion of materials, reaction temperature, and time. The temperature may be controlled by charcoal fire, water bath, etc., and the time is measured by burning incense and dripping. Although the ancient method is different from the scientific accuracy of today, it is possible to use natural things, simple means, and multi-step changes, and it is expected to become this 5-bromo-3-ene-2-methoxycarbonyl benzyl ether.
First of all, its appearance is often crystalline, white or yellowish in color, with a certain luster, delicate and regular, and it looks like fine salt. This form is easy to observe and use, and it is easy to handle in many experiments and production links.
As for the melting point, it is about a specific temperature range. Due to the intermolecular force, when the temperature rises to a certain value, the energy of the lattice is sufficient to overcome the intermolecular binding, causing it to change from solid to liquid. Accurate melting point data is a key indicator for identifying the authenticity and purity of this product. If it contains impurities, the melting point is often shifted, or lowered, or the melting range becomes wider.
The boiling point is also an important physical property. Under a specific pressure, when this product reaches a certain temperature, it boils and turns from liquid to gaseous. The level of boiling point is closely related to the molecular structure. The structure of complex functional groups increases the intermolecular force and the boiling point increases accordingly. This property can be separated from other products by distillation in the process of separation and purification.
In terms of solubility, it has a certain solubility in organic solvents such as ethanol and ether. Because its molecular structure contains polar and non-polar parts, the polar carbonyl group and methoxy group interact with the polar part of the organic solvent, and the non-polar naphthalene ring and alkene structure are also compatible with the non-polar part of the organic solvent. However, in water, the solubility is very small, because water is a strong polar solvent, it does not match the molecular force of the substance.
The density is higher than that of water, and if it is placed in water, it will sink to the bottom of the water. This property is an important guide in operations such as liquid-liquid separation. If mixed with water, the two can be separated by the method of liquid separation by the difference in density.
The refractive index also has characteristics. When light passes through this material, the propagation direction changes, and the refractive index reflects its ability to refract light. Different purity products have slightly different refractive indices, which is another way to detect purity.
In summary, the physical properties of 5-alkane-3-ene-2-methoxycarbonyl oxybenzoyl naphthalene, such as appearance, melting point, boiling point, solubility, density, refractive index, etc., are of crucial significance for their identification, separation, purification and application.
There is a methoxycarbonyl group in its molecule, and the alkyl group gives the compound a certain amount of water resistance. Because of its carbonyl properties, it can form water molecules. In addition, carbonyl carbons have certain positive properties and are vulnerable to nuclear attack and nuclear substitution. For example, the nucleus of an alcohol can be reacted to this carbonyl group to form a new ester compound. In this process, the alkoxy group replaces the original methoxy group, and the molecular properties are changed.
Furthermore, the benzyl part makes the compound have a certain degree of characterization. The benzene in the benzyl group has a co-system, which can disperse the molecules and reduce the energy of the whole molecule. In some reversals, the benzyl group can be retained as a given element, or the reversals of the benzyl position can be generated under specific conditions. For example, the benzyl atom at the benzyl position can be oxidized under the action of oxidation to form derivatives such as benzyl alcohol, benzaldehyde, and even benzoic acid.
Therefore, 5-%-3-ene-2-methoxycarbonyl benzyl exhibits a variety of chemical properties due to the different groups contained in it, and has a certain anti-chemical activity in the field of chemical synthesis. It can be used to synthesize various chemical compounds through reasonable anti-chemical components.
First, this substance has a certain chemical activity. When encountering strong oxidants, strong acids and bases, or causing violent reactions, causing material deterioration, and even leading to safety accidents. Therefore, when storing, it must be placed separately from oxidants, acids and bases, and choose a cool, dry, well-ventilated place, away from fire and heat sources. If the storage environment temperature is too high, it may cause the compound to decompose and evaporate, affecting its quality and stability.
Second, when transporting, be sure to follow the relevant regulations on the transportation of dangerous chemicals. Packaging should be solid and tight, anti-leakage and anti-damage. The requirements for transportation vehicles are also strict, and there must be perfect fire prevention, explosion-proof and anti-leakage measures. Drivers and escorts should also have professional knowledge and emergency handling capabilities.
Third, 5-alkane-3-ene-2-methoxycarbonyl naphthalene may be toxic and irritating. During storage and transportation, the operator must take appropriate protective measures, such as protective clothing, protective gloves and goggles, to avoid skin contact and inhalation. In case of accidental contact, rinse with plenty of water immediately and seek medical treatment.
Fourth, due to the particularity of its chemical properties, there are also requirements for the material of the storage container. Generally, materials with good chemical stability, such as specific glass materials or corrosion-resistant plastics, are selected to prevent chemical reactions between the container and the compound and affect the quality of the substance. And the storage place should be clearly marked to remind personnel to pay attention to safety.

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