Linshang Chemical
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5-(Chloromethyl)-1,2,3-Trimethoxybenzene
Linshang Chemical
|
HS Code |
419435 |
| Chemical Formula | C10H13ClO3 |
| Molar Mass | 216.66 g/mol |
| Appearance | Typically a colorless to light - colored liquid or solid |
| Solubility | Soluble in organic solvents like dichloromethane, chloroform, and toluene; insoluble in water |
| Density | Estimated to be around 1.1 - 1.3 g/cm³ based on similar aromatic - chloromethyl - methoxy compounds |
| Odor | May have a characteristic aromatic odor |
| Stability | Stable under normal conditions, but can react with strong oxidizing agents, nucleophiles due to the reactive chloromethyl group |
As an accredited 5-(Chloromethyl)-1,2,3-Trimethoxybenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of (chloromethyl)-1,2,3 - trimethoxybenzene packaged in a sealed plastic bottle. |
| Storage | Store 5-(chloromethyl)-1,2,3 -trimethoxybenzene in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly closed container, preferably made of corrosion - resistant material. Due to its potential reactivity, isolate it from oxidizing agents, reducing agents, and nucleophiles to prevent unwanted chemical reactions. |
| Shipping | 5-(Chloromethyl)-1,2,3 -trimethoxybenzene is shipped in sealed, corrosion - resistant containers. Compliance with chemical transportation regulations ensures safe transit, protecting from physical damage and environmental exposure. |
Competitive 5-(Chloromethyl)-1,2,3-Trimethoxybenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 5-(Chloromethyl)-1,2,3-Trimethoxybenzene in China?
As a trusted 5-(Chloromethyl)-1,2,3-Trimethoxybenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 5-(Chloromethyl)-1,2,3-Trimethoxybenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the main use of 5- (chloromethyl) -1,2,3-trimethoxybenzene?
5- (chloromethyl) -1,2,3-trimethoxy benzene has a wide range of uses. In the field of organic synthesis, this compound is often used as a key intermediate. Due to its structure containing chloromethyl and trimethoxy groups, the two give it unique reactivity.
In the field of pharmaceutical chemistry, with its specific chemical structure, it can build complex molecular structures with biological activity through a series of chemical reactions, and then develop new drugs. For example, in the synthesis of some anti-tumor drugs, 5- (chloromethyl) -1,2,3-trimethoxy benzene can be used as one of the starting materials, and other functional groups can be gradually introduced through multi-step reactions, eventually forming compounds with targeted anti-tumor effects.
is also useful in materials science. Through its reaction with other organic or inorganic materials, new materials with special properties may be prepared. For example, by reacting with specific polymer monomers, the properties of the polymer can be changed, such as solubility and thermal stability, etc., thereby meeting the requirements of material properties in different application scenarios.
In the fragrance industry, due to its unique chemical composition, it can be used as an important intermediate for the synthesis of special fragrances. After a series of reaction modifications, the resulting product may have a unique aroma, which can be applied to the preparation of perfumes, flavors and other products, adding a different flavor to the fragrance industry.
In conclusion, the unique structure of 5- (chloromethyl) -1,2,3-trimethoxybenzene has important uses in many fields such as organic synthesis, drug research and development, materials science and fragrance industry, providing a key chemical raw material basis for the development of various fields.
In the field of pharmaceutical chemistry, with its specific chemical structure, it can build complex molecular structures with biological activity through a series of chemical reactions, and then develop new drugs. For example, in the synthesis of some anti-tumor drugs, 5- (chloromethyl) -1,2,3-trimethoxy benzene can be used as one of the starting materials, and other functional groups can be gradually introduced through multi-step reactions, eventually forming compounds with targeted anti-tumor effects.
is also useful in materials science. Through its reaction with other organic or inorganic materials, new materials with special properties may be prepared. For example, by reacting with specific polymer monomers, the properties of the polymer can be changed, such as solubility and thermal stability, etc., thereby meeting the requirements of material properties in different application scenarios.
In the fragrance industry, due to its unique chemical composition, it can be used as an important intermediate for the synthesis of special fragrances. After a series of reaction modifications, the resulting product may have a unique aroma, which can be applied to the preparation of perfumes, flavors and other products, adding a different flavor to the fragrance industry.
In conclusion, the unique structure of 5- (chloromethyl) -1,2,3-trimethoxybenzene has important uses in many fields such as organic synthesis, drug research and development, materials science and fragrance industry, providing a key chemical raw material basis for the development of various fields.
What are the physical properties of 5- (chloromethyl) -1,2,3-trimethoxybenzene
5- (chloromethyl) -1,2,3-trimethoxybenzene is a kind of organic compound. Its physical properties are very critical, and its applications in many fields such as chemical industry are related to it.
Looking at its properties, it is mostly colorless to light yellow liquid under normal conditions. This color and physical state can be an important characterization in actual operation and identification. It has a certain volatility and can slowly dissipate in the air in an open environment.
The boiling point is about a specific temperature range. This temperature data is crucial for its separation, purification and reaction control under different temperature conditions. Due to the established boiling point, it can be precisely separated from the mixture by means of distillation and other means.
Melting point is also one of the important physical properties. Although it is not the state of normal temperature, it is also indispensable when low temperature experiments or storage conditions are set. Knowing the melting point can prevent it from solidifying at improper low temperatures and affect subsequent use.
In terms of density, there is a specific value. This value is related to the stratification when it is mixed with other substances. In liquid-liquid reactions or extraction operations, a reasonable process can be designed accordingly.
Solubility is also worthy of attention. It is soluble in some organic solvents, such as common ethanol, ether, etc., but has poor solubility in water. This property is a factor that must be considered when selecting reaction solvents and product purification.
The physical properties of 5- (chloromethyl) -1,2,3-trimethoxylbenzene have their own uses. They are all basic and key elements in chemical production, scientific research experiments and many other aspects. Make good use of them to make them play their due effectiveness in various fields.
Looking at its properties, it is mostly colorless to light yellow liquid under normal conditions. This color and physical state can be an important characterization in actual operation and identification. It has a certain volatility and can slowly dissipate in the air in an open environment.
The boiling point is about a specific temperature range. This temperature data is crucial for its separation, purification and reaction control under different temperature conditions. Due to the established boiling point, it can be precisely separated from the mixture by means of distillation and other means.
Melting point is also one of the important physical properties. Although it is not the state of normal temperature, it is also indispensable when low temperature experiments or storage conditions are set. Knowing the melting point can prevent it from solidifying at improper low temperatures and affect subsequent use.
In terms of density, there is a specific value. This value is related to the stratification when it is mixed with other substances. In liquid-liquid reactions or extraction operations, a reasonable process can be designed accordingly.
Solubility is also worthy of attention. It is soluble in some organic solvents, such as common ethanol, ether, etc., but has poor solubility in water. This property is a factor that must be considered when selecting reaction solvents and product purification.
The physical properties of 5- (chloromethyl) -1,2,3-trimethoxylbenzene have their own uses. They are all basic and key elements in chemical production, scientific research experiments and many other aspects. Make good use of them to make them play their due effectiveness in various fields.
What are the synthesis methods of 5- (chloromethyl) -1,2,3-trimethoxybenzene
There are various ways to synthesize 5- (chloromethyl) -1,2,3-trimethoxybenzene. First, it can be obtained by chloromethylation starting from 1,2,3-trimethoxybenzene. In this reaction, the commonly used reagents are polyformaldehyde and hydrogen chloride. First, place 1,2,3-trimethoxybenzene in a suitable reaction vessel, dissolve it with an inert solvent such as dichloromethane, then slowly add polyformaldehyde, and at the same time introduce dry hydrogen chloride gas. During the reaction, attention should be paid to the control of temperature, generally between low temperature and room temperature. After the reaction, the target product can be obtained through post-treatment steps such as extraction, washing, drying and column chromatography.
Second, 1,2,3-trimethoxybenzoic acid can also be used as a raw material. First reduce it to 1,2,3-trimethoxybenzyl alcohol, commonly used reducing agents such as sodium borohydride-boron trifluoride ethyl ether complex. After obtaining 1,2,3-trimethoxybenzyl alcohol, it is then treated with a chlorinating reagent such as thionyl chloride, so that it can be chlorinated and converted into 5- (chloromethyl) -1,2,3-trimethoxybenzene. In this process, the reduction step needs to pay attention to the mild reaction conditions to avoid excessive reduction; the chlorination step needs to control the amount of chlorination reagent and reaction time to prevent side reactions from occurring. After the reaction, it also needs to be separated and purified to obtain a pure product.
Or from other related aromatic compounds, methoxy and chloromethyl are gradually introduced through multi-step reactions, but such methods are often complicated and costly, and are rarely used unless there are special needs. Overall, the former two methods are relatively simple and efficient, and are more commonly used in laboratory synthesis and preparation of a certain scale.
Second, 1,2,3-trimethoxybenzoic acid can also be used as a raw material. First reduce it to 1,2,3-trimethoxybenzyl alcohol, commonly used reducing agents such as sodium borohydride-boron trifluoride ethyl ether complex. After obtaining 1,2,3-trimethoxybenzyl alcohol, it is then treated with a chlorinating reagent such as thionyl chloride, so that it can be chlorinated and converted into 5- (chloromethyl) -1,2,3-trimethoxybenzene. In this process, the reduction step needs to pay attention to the mild reaction conditions to avoid excessive reduction; the chlorination step needs to control the amount of chlorination reagent and reaction time to prevent side reactions from occurring. After the reaction, it also needs to be separated and purified to obtain a pure product.
Or from other related aromatic compounds, methoxy and chloromethyl are gradually introduced through multi-step reactions, but such methods are often complicated and costly, and are rarely used unless there are special needs. Overall, the former two methods are relatively simple and efficient, and are more commonly used in laboratory synthesis and preparation of a certain scale.
What are the precautions for 5- (chloromethyl) -1,2,3-trimethoxybenzene during storage and transportation?
5 - (chloromethyl) - 1,2,3 - trimethoxybenzene, many matters should be paid attention to during storage and transportation. This substance has certain chemical activity and the first environmental conditions. When storing, it is advisable to choose a cool, dry and well-ventilated place. Cover it with fear of moisture and heat. If it is in a high temperature and humid environment, it may cause chemical reactions and damage its quality.
During transportation, caution is also required. It is necessary to ensure that the packaging is intact to prevent leakage. Because it contains chloromethyl, it may be corrosive and irritating to a certain extent. If it leaks, it will not only stain the surroundings, but also endanger the safety of transportation personnel. Furthermore, the means of transportation should also be clean and dry to avoid mixing with other chemicals to prevent dangerous reactions.
Furthermore, this substance may be harmful to the human body. People who store and transport should prepare protective equipment, such as gloves, goggles and gas masks, to guard against possible hazards. And during operation, be sure to strictly abide by safety procedures, handle it with care, and do not slack in the slightest.
In short, 5- (chloromethyl) -1,2,3-trimethoxybenzene must be carefully paid attention to during storage and transportation, from the environment, packaging to personnel protection, in order to ensure its safety and quality.
During transportation, caution is also required. It is necessary to ensure that the packaging is intact to prevent leakage. Because it contains chloromethyl, it may be corrosive and irritating to a certain extent. If it leaks, it will not only stain the surroundings, but also endanger the safety of transportation personnel. Furthermore, the means of transportation should also be clean and dry to avoid mixing with other chemicals to prevent dangerous reactions.
Furthermore, this substance may be harmful to the human body. People who store and transport should prepare protective equipment, such as gloves, goggles and gas masks, to guard against possible hazards. And during operation, be sure to strictly abide by safety procedures, handle it with care, and do not slack in the slightest.
In short, 5- (chloromethyl) -1,2,3-trimethoxybenzene must be carefully paid attention to during storage and transportation, from the environment, packaging to personnel protection, in order to ensure its safety and quality.
What are the effects of 5- (chloromethyl) -1,2,3-trimethoxybenzene on the environment and human health?
5- (chloromethyl) -1,2,3-trimethoxybenzene has potential effects on both the environment and human health. If this substance escapes into the environment, it may endanger the ecological balance. It may be toxic to aquatic organisms and can disrupt the normal operation of aquatic ecosystems, hindering the survival and reproduction of many aquatic organisms. And because of its chemical properties, or it persists in the environment, it is difficult to degrade, thus accumulating, causing pollution to expand and deepen.
As for human health, this substance may pose a risk. If the human body is exposed to it through breathing, skin contact or ingestion, it may cause different health problems. It may irritate the skin and eyes, causing redness, swelling and pain. If inhaled into the body, it may damage the respiratory system, cause coughing, asthma, and even affect lung function. Under long-term exposure, it may also be potentially carcinogenic, causing damage to the genetic material of human cells and increasing the risk of cancer. Therefore, when producing and using products containing this substance, it is necessary to take proper protective measures to protect the environment and personal safety.
As for human health, this substance may pose a risk. If the human body is exposed to it through breathing, skin contact or ingestion, it may cause different health problems. It may irritate the skin and eyes, causing redness, swelling and pain. If inhaled into the body, it may damage the respiratory system, cause coughing, asthma, and even affect lung function. Under long-term exposure, it may also be potentially carcinogenic, causing damage to the genetic material of human cells and increasing the risk of cancer. Therefore, when producing and using products containing this substance, it is necessary to take proper protective measures to protect the environment and personal safety.
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