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5-Nitro-1,2,4-Trichlorobenzene
Linshang Chemical
|
HS Code |
204463 |
| Chemical Formula | C6H2Cl3NO2 |
| Molar Mass | 226.44 g/mol |
| Appearance | Yellow - brown solid |
| Boiling Point | Approximately 305 - 307 °C |
| Melting Point | 82 - 84 °C |
| Density | 1.65 g/cm³ |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in many organic solvents like benzene, toluene |
| Vapor Pressure | Low vapor pressure |
As an accredited 5-Nitro-1,2,4-Trichlorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 5 - nitro - 1,2,4 - trichlorobenzene in 5 - kg sealed drums for chemical packaging. |
| Storage | 5 - nitro - 1,2,4 - trichlorobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames to prevent combustion or decomposition. It should be stored in a tightly sealed container, preferably made of corrosion - resistant materials, to avoid leakage. Keep it separate from incompatible substances like oxidizing agents and bases to prevent dangerous reactions. |
| Shipping | 5 - nitro - 1,2,4 - trichlorobenzene is a chemical. It should be shipped in accordance with strict hazardous materials regulations. Use proper packaging to prevent leakage and ensure safe transportation to the destination. |
Competitive 5-Nitro-1,2,4-Trichlorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
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As a leading 5-Nitro-1,2,4-Trichlorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 5-nitro-1,2,4-trichlorobenzene?
5-Cyano-1,2,4-triazole is an important organic compound. It has a wide range of main uses and has significant effects in many fields.
In the field of medicine, 5-cyano-1,2,4-triazole is often a key intermediate in the synthesis of many drugs. Due to its unique chemical structure, it can participate in the construction of drug molecules and endow drugs with specific biological activities, such as antibacterial, antiviral, and anti-tumor. By interacting with specific targets in organisms, it interferes with the physiological processes of pathogens or tumor cells, thus exerting therapeutic effects.
This compound also plays an important role in pesticides. It can be used as a raw material for the synthesis of high-efficiency pesticides, and the prepared pesticides have excellent inhibition and killing ability against pests, pathogens and other pests. It can precisely act on the specific physiological links of pests, reduce the impact on the environment and non-target organisms, and help to achieve sustainable agricultural development.
In the field of materials science, 5-cyano-1,2,4-triazole can be used to prepare functional materials with excellent performance. For example, participate in the synthesis of polymer materials to improve the thermal stability and mechanical properties of materials. Due to its special structure, it can interact with polymer chains to form a stable network structure and improve the comprehensive properties of materials. It is widely used in high-end fields such as aerospace and electronics.
In addition, in organic synthetic chemistry, 5-cyano-1,2,4-triazole, as an important synthesizer, participates in many organic reactions, providing an effective way for the construction of complex organic molecules and promoting the development of organic synthetic chemistry.
In the field of medicine, 5-cyano-1,2,4-triazole is often a key intermediate in the synthesis of many drugs. Due to its unique chemical structure, it can participate in the construction of drug molecules and endow drugs with specific biological activities, such as antibacterial, antiviral, and anti-tumor. By interacting with specific targets in organisms, it interferes with the physiological processes of pathogens or tumor cells, thus exerting therapeutic effects.
This compound also plays an important role in pesticides. It can be used as a raw material for the synthesis of high-efficiency pesticides, and the prepared pesticides have excellent inhibition and killing ability against pests, pathogens and other pests. It can precisely act on the specific physiological links of pests, reduce the impact on the environment and non-target organisms, and help to achieve sustainable agricultural development.
In the field of materials science, 5-cyano-1,2,4-triazole can be used to prepare functional materials with excellent performance. For example, participate in the synthesis of polymer materials to improve the thermal stability and mechanical properties of materials. Due to its special structure, it can interact with polymer chains to form a stable network structure and improve the comprehensive properties of materials. It is widely used in high-end fields such as aerospace and electronics.
In addition, in organic synthetic chemistry, 5-cyano-1,2,4-triazole, as an important synthesizer, participates in many organic reactions, providing an effective way for the construction of complex organic molecules and promoting the development of organic synthetic chemistry.
What are the environmental effects of 5-nitro-1,2,4-trichlorobenzene?
5-Cyano-1,2,4-trifluorobenzene has a complex impact on the environment. Its properties are chemically active, if it escapes from nature, or involves multiple environmental processes.
First words aquatic ecology, if this compound enters the water body, it may be a toxin source for aquatic organisms. Its chemical structure is special, or it interferes with the physiological functions of aquatic organisms, causing growth and reproduction to be hindered. Such as fish or abnormal development, the survival rate of larvae decreases; plankton or metabolic disorders affect the foundation of the water food chain and eventually lead to water ecological imbalance.
Second and soil environment, if it seeps into the soil, or changes the soil chemical properties, it affects the soil microbial community. Microorganisms are crucial for soil nutrient cycling and organic matter decomposition. Their communities are disturbed or cause soil fertility changes, which affects plant growth. Plants may have abnormal nutrient uptake and stunted growth, which indirectly affects the energy flow and material cycle of terrestrial ecosystems.
Furthermore, in the atmospheric environment, if 5-cyano-1,2,4-trifluorobenzene volatilizes, it may participate in atmospheric chemical reactions and affect the atmospheric chemical composition. Although the amount may be small, it accumulates over a long period of time, or has a gradual impact on air quality, and may be transported through atmospheric circulation, resulting in an expansion of the impact range.
Because of its certain stability, it is difficult to degrade in the environment, or remains for a long time, and continues to be a burden on the environment. It may also be enriched in organisms, passed through the food chain, and concentrated in high-trophic organisms, posing a potential threat to biodiversity and ecological balance.
Therefore, 5-cyano-1,2,4-trifluorobenzene has a wide and far-reaching impact on the environment, and it should be handled with caution to prevent it from causing irreversible damage to ecosystems.
First words aquatic ecology, if this compound enters the water body, it may be a toxin source for aquatic organisms. Its chemical structure is special, or it interferes with the physiological functions of aquatic organisms, causing growth and reproduction to be hindered. Such as fish or abnormal development, the survival rate of larvae decreases; plankton or metabolic disorders affect the foundation of the water food chain and eventually lead to water ecological imbalance.
Second and soil environment, if it seeps into the soil, or changes the soil chemical properties, it affects the soil microbial community. Microorganisms are crucial for soil nutrient cycling and organic matter decomposition. Their communities are disturbed or cause soil fertility changes, which affects plant growth. Plants may have abnormal nutrient uptake and stunted growth, which indirectly affects the energy flow and material cycle of terrestrial ecosystems.
Furthermore, in the atmospheric environment, if 5-cyano-1,2,4-trifluorobenzene volatilizes, it may participate in atmospheric chemical reactions and affect the atmospheric chemical composition. Although the amount may be small, it accumulates over a long period of time, or has a gradual impact on air quality, and may be transported through atmospheric circulation, resulting in an expansion of the impact range.
Because of its certain stability, it is difficult to degrade in the environment, or remains for a long time, and continues to be a burden on the environment. It may also be enriched in organisms, passed through the food chain, and concentrated in high-trophic organisms, posing a potential threat to biodiversity and ecological balance.
Therefore, 5-cyano-1,2,4-trifluorobenzene has a wide and far-reaching impact on the environment, and it should be handled with caution to prevent it from causing irreversible damage to ecosystems.
What are the physical properties of 5-nitro-1,2,4-trichlorobenzene?
5-Cyano-1,2,4-trifluorobenzene is one of the organic compounds. Its physical properties are quite characteristic, let me tell you one by one.
Looking at its appearance, it is often colorless to light yellow liquid. This color state is easy to identify. In many chemical reactions and industrial applications, its appearance can be used to preliminarily judge its state and purity.
When it comes to the boiling point, it is about a certain range. This boiling point characteristic is of great significance in the process of separation and purification. By controlling the temperature, it can be effectively separated from the mixture to obtain a pure product, just as it is used to screen the advantages and disadvantages, remove the barren and store the cyanine.
Its melting point also has a fixed number. This value is the inherent property of the substance, just like the human nature, under specific conditions, it presents a unique state. The existence of the melting point provides an important basis for the identification of the substance, and also provides a reference for temperature control in order to maintain the stability of its physical state during storage and transportation.
The density of 5-cyano-1,2,4-trifluorobenzene is also a key physical property. The density is related to its floating and mixing characteristics in different media. In the operation of liquid mixing, the difference in density can cause the material to stratify or affect the degree of uniform mixing. This is subtle and needs to be carefully controlled.
Furthermore, in terms of solubility, it is soluble in some organic solvents, but limited in water. This solubility characteristic is crucial in the solvent selection and product separation steps of chemical reactions. Only by choosing the right solvent can the reaction proceed smoothly, and the product can be easily separated to improve the yield and purity.
These physical properties are interrelated and affect each other. They are indispensable factors in chemical synthesis, materials science and many other fields. Research and grasp of them can help us make good use of them and maximize their function.
Looking at its appearance, it is often colorless to light yellow liquid. This color state is easy to identify. In many chemical reactions and industrial applications, its appearance can be used to preliminarily judge its state and purity.
When it comes to the boiling point, it is about a certain range. This boiling point characteristic is of great significance in the process of separation and purification. By controlling the temperature, it can be effectively separated from the mixture to obtain a pure product, just as it is used to screen the advantages and disadvantages, remove the barren and store the cyanine.
Its melting point also has a fixed number. This value is the inherent property of the substance, just like the human nature, under specific conditions, it presents a unique state. The existence of the melting point provides an important basis for the identification of the substance, and also provides a reference for temperature control in order to maintain the stability of its physical state during storage and transportation.
The density of 5-cyano-1,2,4-trifluorobenzene is also a key physical property. The density is related to its floating and mixing characteristics in different media. In the operation of liquid mixing, the difference in density can cause the material to stratify or affect the degree of uniform mixing. This is subtle and needs to be carefully controlled.
Furthermore, in terms of solubility, it is soluble in some organic solvents, but limited in water. This solubility characteristic is crucial in the solvent selection and product separation steps of chemical reactions. Only by choosing the right solvent can the reaction proceed smoothly, and the product can be easily separated to improve the yield and purity.
These physical properties are interrelated and affect each other. They are indispensable factors in chemical synthesis, materials science and many other fields. Research and grasp of them can help us make good use of them and maximize their function.
What are the chemical properties of 5-nitro-1,2,4-trichlorobenzene?
5-Amino-1,2,4-triazole is an organic compound with unique chemical properties and important uses in many fields. The following is your detailed description:
First of all, 5-amino-1,2,4-triazole is weakly basic. Due to the presence of nitrogen atoms in its molecular structure, the lone pair electrons on the nitrogen atoms can bind protons, thus exhibiting alkaline characteristics. This property allows it to play a role in some acid-base reactions and react with acids to form corresponding salts.
Secondly, the compound has a certain coordination ability. The nitrogen atom of 5-amino-1,2,4-triazole can be used as a ligand to form coordination bonds with metal ions by virtue of its lone pair electrons. These complexes are of great significance in the fields of materials science and catalysis. For example, in catalytic reactions, their complexes may exhibit unique catalytic activity and selectivity, which can help the efficient development of specific chemical reactions.
Furthermore, 5-amino-1,2,4-triazole has good stability. Under normal conditions, it is not prone to decomposition reactions and can exist relatively stably. However, under some specific conditions, such as high temperature and strong oxidants, its stability will be affected, and corresponding chemical reactions will occur.
In addition, it is an extremely important intermediate in the field of organic synthesis. With the help of the amino group and triazole ring in its molecular structure, other functional groups can be introduced through a series of organic reactions to synthesize organic compounds with more complex structures and functions. These compounds are widely used in pharmaceutical chemistry, pesticide chemistry and other fields, such as the development of drugs or pesticides with specific biological activities.
The chemical properties of 5-amino-1,2,4-triazole make it occupy an important position in many fields. With the continuous deepening of research, its potential application value is expected to be more fully explored and utilized.
First of all, 5-amino-1,2,4-triazole is weakly basic. Due to the presence of nitrogen atoms in its molecular structure, the lone pair electrons on the nitrogen atoms can bind protons, thus exhibiting alkaline characteristics. This property allows it to play a role in some acid-base reactions and react with acids to form corresponding salts.
Secondly, the compound has a certain coordination ability. The nitrogen atom of 5-amino-1,2,4-triazole can be used as a ligand to form coordination bonds with metal ions by virtue of its lone pair electrons. These complexes are of great significance in the fields of materials science and catalysis. For example, in catalytic reactions, their complexes may exhibit unique catalytic activity and selectivity, which can help the efficient development of specific chemical reactions.
Furthermore, 5-amino-1,2,4-triazole has good stability. Under normal conditions, it is not prone to decomposition reactions and can exist relatively stably. However, under some specific conditions, such as high temperature and strong oxidants, its stability will be affected, and corresponding chemical reactions will occur.
In addition, it is an extremely important intermediate in the field of organic synthesis. With the help of the amino group and triazole ring in its molecular structure, other functional groups can be introduced through a series of organic reactions to synthesize organic compounds with more complex structures and functions. These compounds are widely used in pharmaceutical chemistry, pesticide chemistry and other fields, such as the development of drugs or pesticides with specific biological activities.
The chemical properties of 5-amino-1,2,4-triazole make it occupy an important position in many fields. With the continuous deepening of research, its potential application value is expected to be more fully explored and utilized.
What is the preparation method of 5-nitro-1,2,4-trichlorobenzene?
To prepare 5-cyano-1,2,4-trifluorobenzene, you can follow the following method:
First take 1,2,4-trifluorobenzene as the starting material. Place 1,2,4-trifluorobenzene in an appropriate reaction vessel and first cool it at low temperature, about to reduce the temperature to -10 ° C to 0 ° C. In this low temperature environment, slowly add an appropriate amount of fuming sulfuric acid, add caution and keep stirring to make the mixture uniform. The ratio of fuming sulfuric acid to 1,2,4-trifluorobenzene is determined according to the stoichiometry and the actual needs of the reaction. It is probably a little too much fuming sulfuric acid, which can ensure the full reaction of 1,2,4-trifluorobenzene.
After adding fuming sulfuric acid, keep stirring and gradually heat up to 30 ° C - 40 ° C. The reaction at this temperature lasts for a period of time, about 2-3 hours, so that 1,2,4-trifluorobenzene and fuming sulfuric acid can fully react to obtain 1,2,4-trifluorobenzene sulfuric acid.
After the reaction is completed, pour the reaction mixture into a large amount of ice water, stir well, so that 1,2,4-trifluorobenzene sulfuric acid can be fully dissolved and separated. Extract several times with an appropriate organic solvent, such as ether, and combine the organic phases. After that, dry the organic phase with anhydrous sodium sulfate, filter out the desiccant, and remove the organic solvent by distillation under reduced pressure to obtain a relatively pure 1,2,4-trifluorobenzene sulfuric acid.
Place 1,2,4-trifluorobenzenesulfonic acid and cuprous cyanide in another reaction vessel at a time, add an appropriate amount of N, N-dimethylformamide (DMF) as solvent, and stir well. The ratio of cuprous cyanide to 1,2,4-trifluorobenzenesulfonic acid is precisely prepared according to stoichiometry to ensure sufficient reaction. Then, heat up to 120 ° C - 130 ° C, and continue the reaction at this temperature for about 4-5 hours. During the reaction, pay close attention to the reaction process, and see the change of color and state of the system.
When the reaction is over, cool the reaction mixture to room temperature, pour an appropriate amount of dilute hydrochloric acid solution, and stir. At this time, a precipitation can be seen. Filter and collect the precipitation, and wash the precipitation with water several times to remove impurities. After that, the precipitation is purified by recrystallization with an appropriate organic solvent, such as ethanol, filtered and dried to obtain 5-cyano-1,2,4-trifluorobenzene.
During the entire preparation process, it is necessary to strictly abide by the chemical operation specifications and pay attention to safety. For example, fuming sulfuric acid is highly corrosive, and cuprous cyanide is highly toxic. Be careful when operating, work in a well-ventilated place, and take protective measures.
First take 1,2,4-trifluorobenzene as the starting material. Place 1,2,4-trifluorobenzene in an appropriate reaction vessel and first cool it at low temperature, about to reduce the temperature to -10 ° C to 0 ° C. In this low temperature environment, slowly add an appropriate amount of fuming sulfuric acid, add caution and keep stirring to make the mixture uniform. The ratio of fuming sulfuric acid to 1,2,4-trifluorobenzene is determined according to the stoichiometry and the actual needs of the reaction. It is probably a little too much fuming sulfuric acid, which can ensure the full reaction of 1,2,4-trifluorobenzene.
After adding fuming sulfuric acid, keep stirring and gradually heat up to 30 ° C - 40 ° C. The reaction at this temperature lasts for a period of time, about 2-3 hours, so that 1,2,4-trifluorobenzene and fuming sulfuric acid can fully react to obtain 1,2,4-trifluorobenzene sulfuric acid.
After the reaction is completed, pour the reaction mixture into a large amount of ice water, stir well, so that 1,2,4-trifluorobenzene sulfuric acid can be fully dissolved and separated. Extract several times with an appropriate organic solvent, such as ether, and combine the organic phases. After that, dry the organic phase with anhydrous sodium sulfate, filter out the desiccant, and remove the organic solvent by distillation under reduced pressure to obtain a relatively pure 1,2,4-trifluorobenzene sulfuric acid.
Place 1,2,4-trifluorobenzenesulfonic acid and cuprous cyanide in another reaction vessel at a time, add an appropriate amount of N, N-dimethylformamide (DMF) as solvent, and stir well. The ratio of cuprous cyanide to 1,2,4-trifluorobenzenesulfonic acid is precisely prepared according to stoichiometry to ensure sufficient reaction. Then, heat up to 120 ° C - 130 ° C, and continue the reaction at this temperature for about 4-5 hours. During the reaction, pay close attention to the reaction process, and see the change of color and state of the system.
When the reaction is over, cool the reaction mixture to room temperature, pour an appropriate amount of dilute hydrochloric acid solution, and stir. At this time, a precipitation can be seen. Filter and collect the precipitation, and wash the precipitation with water several times to remove impurities. After that, the precipitation is purified by recrystallization with an appropriate organic solvent, such as ethanol, filtered and dried to obtain 5-cyano-1,2,4-trifluorobenzene.
During the entire preparation process, it is necessary to strictly abide by the chemical operation specifications and pay attention to safety. For example, fuming sulfuric acid is highly corrosive, and cuprous cyanide is highly toxic. Be careful when operating, work in a well-ventilated place, and take protective measures.
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