Linshang Chemical
PRODUCTS
Benzene, 1-(2-Bromoethoxy)-4-Chloro-
Linshang Chemical
|
HS Code |
279730 |
| Chemical Formula | C8H8BrClO |
| Molecular Weight | 235.506 g/mol |
| Appearance | Solid (predicted) |
| Boiling Point | Approx. 282 - 283 °C (predicted) |
| Melting Point | Approx. 43 - 45 °C (predicted) |
| Density | Approx. 1.598 g/cm³ (predicted) |
| Logp | Approx. 3.55 (predicted) |
| Solubility In Water | Low (predicted) |
| Flash Point | Approx. 124.4 °C (predicted) |
| Vapor Pressure | Very low (predicted) |
As an accredited Benzene, 1-(2-Bromoethoxy)-4-Chloro- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100 - gram vial packaging for 1-(2 - bromoethoxy)-4 - chloro - benzene chemical. |
| Storage | Store "Benzene, 1-(2 - bromoethoxy)-4 - chloro -" in a cool, dry, well - ventilated area away from heat, sparks, and open flames. Keep it in a tightly - sealed container, preferably made of corrosion - resistant materials. Isolate it from oxidizing agents, strong acids, and bases to prevent chemical reactions. Label the storage clearly for easy identification and safety. |
| Shipping | "1-(2 - bromoethoxy)-4 - chlorobenzene should be shipped in tightly - sealed containers, compliant with hazardous chemical regulations. Ensure proper labeling for its chemical nature and handle with care to prevent spills during transit." |
Competitive Benzene, 1-(2-Bromoethoxy)-4-Chloro- prices that fit your budget—flexible terms and customized quotes for every order.
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As a leading Benzene, 1-(2-Bromoethoxy)-4-Chloro- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the chemical properties of this product 1- (2-bromoethoxy) -4-chlorobenzene?
This substance is called 1- (2-hydroxyethoxy) -4-fluorobenzene, which is an organic compound. It is widely used in many fields and plays a key role in chemical and pharmaceutical research and development. Its chemical properties are unique, and the following will be described in the classical Chinese style of "Tiangong Kaiwu".
1- (2-hydroxyethoxy) -4-fluorobenzene, its properties have certain stability. When exposed to strong oxidants, it is like dry firewood when exposed to fire, and it is easy to react violently. This is because in its molecular structure, fluorine atoms are connected to the benzene ring, and the electronegativity of fluorine is high, which causes the electron cloud density of the benzene ring to change and the activity to increase. Strong oxidants have the power to capture electrons, and the two meet, and the electrons transfer
In the acid-base environment, 1- (2-hydroxyethoxy) -4-fluorobenzene also changes. In case of strong acid, just like a tame beast, its hydroxyethoxy group may be protonated. Because strong acid easily provides protons and binds to the oxygen atom of hydroxethoxy, the molecular structure is fine-tuned, and the properties are changed. In case of strong base, the fluorine atom may leave now. The electron cloud distribution on the benzene ring is affected by strong bases, and the fluorine atom is separated from the benzene ring under specific conditions, and a substitution or elimination reaction occurs.
Furthermore, the solubility of 1- (2-hydroxyethoxy) -4-fluorobenzene is also an important property. In organic solvents, such as ethanol and ether, it is like a fish entering water and has good solubility. This is due to the existence of intermolecular forces between organic solvents and the compound, such as van der Waals forces, hydrogen bonds, etc., which promote compatibility between the two. In water, the solubility is relatively poor. Due to the difference between molecular polarity and water polarity, it is difficult to form an effective interaction, so it is difficult to dissolve.
Under heating conditions, the reaction of this compound is more complicated. High temperature is like an invisible hand, stirring the internal structure of the molecule. The stability of the benzene ring may be challenged, and the chemical bond between the hydroxyethoxy group and the benzene ring may be broken, resulting in rearrangement and decomposition, resulting in a variety of products.
The chemical properties of 1- (2-hydroxyethoxy) -4-fluorobenzene are dominated by its structure and exhibit various reactions under different conditions. In the fields of chemical engineering and pharmaceutical synthesis, mastering its properties is the key to good use.
1- (2-hydroxyethoxy) -4-fluorobenzene, its properties have certain stability. When exposed to strong oxidants, it is like dry firewood when exposed to fire, and it is easy to react violently. This is because in its molecular structure, fluorine atoms are connected to the benzene ring, and the electronegativity of fluorine is high, which causes the electron cloud density of the benzene ring to change and the activity to increase. Strong oxidants have the power to capture electrons, and the two meet, and the electrons transfer
In the acid-base environment, 1- (2-hydroxyethoxy) -4-fluorobenzene also changes. In case of strong acid, just like a tame beast, its hydroxyethoxy group may be protonated. Because strong acid easily provides protons and binds to the oxygen atom of hydroxethoxy, the molecular structure is fine-tuned, and the properties are changed. In case of strong base, the fluorine atom may leave now. The electron cloud distribution on the benzene ring is affected by strong bases, and the fluorine atom is separated from the benzene ring under specific conditions, and a substitution or elimination reaction occurs.
Furthermore, the solubility of 1- (2-hydroxyethoxy) -4-fluorobenzene is also an important property. In organic solvents, such as ethanol and ether, it is like a fish entering water and has good solubility. This is due to the existence of intermolecular forces between organic solvents and the compound, such as van der Waals forces, hydrogen bonds, etc., which promote compatibility between the two. In water, the solubility is relatively poor. Due to the difference between molecular polarity and water polarity, it is difficult to form an effective interaction, so it is difficult to dissolve.
Under heating conditions, the reaction of this compound is more complicated. High temperature is like an invisible hand, stirring the internal structure of the molecule. The stability of the benzene ring may be challenged, and the chemical bond between the hydroxyethoxy group and the benzene ring may be broken, resulting in rearrangement and decomposition, resulting in a variety of products.
The chemical properties of 1- (2-hydroxyethoxy) -4-fluorobenzene are dominated by its structure and exhibit various reactions under different conditions. In the fields of chemical engineering and pharmaceutical synthesis, mastering its properties is the key to good use.
What are the applications of 1- (2-bromoethoxy) -4-chlorobenzene in industrial production?
1 - (2 - hydroxyethyl) - 4 - nitrobenzene has many applications in industrial production.
In the dye industry, it can be used as an important intermediate. The nitro and hydroxyethyl groups in the structure of this substance give it unique chemical activity. According to the theory of "Tiangong Kaiwu", the preparation of dyes requires delicate material selection and synthesis methods. 1 - (2 - hydroxyethyl) - 4 - nitrobenzene can be converted into dyes with bright color and excellent fastness through specific chemical reactions. It is used in fabric dyeing to make fabrics rich and lasting.
In the pharmaceutical industry, it also has key uses. Because of its structure, it can participate in a variety of drug synthesis reactions. For example, ancient pharmaceuticals, pay attention to the role of monarch and minister, and the compatibility is appropriate. With this material as the starting material, through reasonable reaction steps, compounds with specific pharmacological activities can be prepared, or as the key components of antibacterial and anti-inflammatory drugs, contributing unique value to the field of medicine.
In the field of organic synthesis, 1- (2-hydroxyethyl) -4-nitrobenzene is like the cornerstone of delicacy. "Tiangong Kaiwu" talks about the principle of creation, and organic synthesis also needs to follow the rules. It can participate in various nucleophilic substitution, reduction and other reactions to construct more complex organic molecular structures, expand the types and functions of organic compounds, and provide basic raw materials for materials science and other related fields.
In the dye industry, it can be used as an important intermediate. The nitro and hydroxyethyl groups in the structure of this substance give it unique chemical activity. According to the theory of "Tiangong Kaiwu", the preparation of dyes requires delicate material selection and synthesis methods. 1 - (2 - hydroxyethyl) - 4 - nitrobenzene can be converted into dyes with bright color and excellent fastness through specific chemical reactions. It is used in fabric dyeing to make fabrics rich and lasting.
In the pharmaceutical industry, it also has key uses. Because of its structure, it can participate in a variety of drug synthesis reactions. For example, ancient pharmaceuticals, pay attention to the role of monarch and minister, and the compatibility is appropriate. With this material as the starting material, through reasonable reaction steps, compounds with specific pharmacological activities can be prepared, or as the key components of antibacterial and anti-inflammatory drugs, contributing unique value to the field of medicine.
In the field of organic synthesis, 1- (2-hydroxyethyl) -4-nitrobenzene is like the cornerstone of delicacy. "Tiangong Kaiwu" talks about the principle of creation, and organic synthesis also needs to follow the rules. It can participate in various nucleophilic substitution, reduction and other reactions to construct more complex organic molecular structures, expand the types and functions of organic compounds, and provide basic raw materials for materials science and other related fields.
What are the synthesis methods of 1- (2-bromoethoxy) -4-chlorobenzene?
To prepare 1 - (2 - hydroxyethyl) - 4 - bromobenzene, the synthesis method is as follows:
First, benzene and ethylene under the action of a suitable catalyst (such as aluminum trichloride and other Lewis acids), the Fu-gram alkylation reaction occurs to generate ethylbenzene. In this reaction, the benzene ring is nucleophilic, and ethylene forms a positive carbon ion under the action of the catalyst, which then undergoes electrophilic substitution with the benzene ring to obtain ethylbenzene.
Then, ethylbenzene is reacted with bromine in the presence of light or initiator. Using the stability of benzyl radical, bromine atoms are introduced at the benzyl position of ethylbenzene to generate 1-bromo-1-phenylethane. This reaction is a radical substitution mechanism. Illumination or initiator prompts bromine molecules to split into bromine radicals and replace with ethylbenzyl hydrogen.
Next, 1-bromo-1-phenylethane undergoes hydrolysis under basic conditions (such as sodium hydroxide aqueous solution), and bromine atoms are replaced by hydroxyl groups to obtain 1-phenylethanol. This is a nucleophilic substitution reaction. Hydroxide ions attack the carbon atoms connected to bromine as nucleophiles, and bromine ions leave.
After that, 1-phenylethanol is oxidized to phenylacetaldehyde under the action of appropriate oxidizing agents (such as isothermal and oxidizing agents of Sarit reagent). This reaction selectively oxidizes the alcohol hydroxyl group to the aldehyde group without affecting other structures such as the phenyl ring.
Then the phenylacetaldehyde and formaldehyde undergo a hydroxyaldehyde condensation reaction under the action of a basic catalyst (such as dilute sodium hydroxide solution) to generate 2-hydroxy-3-phenylpropanal. In this reaction, the α-hydrogen of phenylacetaldehyde leaves under the action of alkali to form carbon anions, which attack the carbonyl carbon of formaldehyde, and obtain the product through a series of processes.
Subsequently, 2-hydroxy-3-phenylpropionaldehyde reacts with hydrobromic acid, and the hydroxyl group is replaced by a bromine atom to form 2-bromo-3-phenylpropionaldehyde. This reaction is nucleophilic substitution, where bromine ions attack the carbon atom attached to the hydroxyl group, and the hydroxyl group leaves in the form of water.
Finally, 2-bromo-3-phenylpropionaldehyde is reduced under certain conditions (such as suitable reducing agent and reaction environment), and the aldehyde group is reduced to hydroxyethyl group, and the bromine atom on the benzene ring remains unchanged, and finally 1- (2-hydroxyethyl) -4-bromobenzene is obtained.
The synthesis process needs to be based on the characteristics of each step of the reaction, and the reaction conditions, such as temperature, pH, reactant ratio, etc., are precisely controlled to improve the reaction yield and selectivity and achieve the expected synthesis goal.
First, benzene and ethylene under the action of a suitable catalyst (such as aluminum trichloride and other Lewis acids), the Fu-gram alkylation reaction occurs to generate ethylbenzene. In this reaction, the benzene ring is nucleophilic, and ethylene forms a positive carbon ion under the action of the catalyst, which then undergoes electrophilic substitution with the benzene ring to obtain ethylbenzene.
Then, ethylbenzene is reacted with bromine in the presence of light or initiator. Using the stability of benzyl radical, bromine atoms are introduced at the benzyl position of ethylbenzene to generate 1-bromo-1-phenylethane. This reaction is a radical substitution mechanism. Illumination or initiator prompts bromine molecules to split into bromine radicals and replace with ethylbenzyl hydrogen.
Next, 1-bromo-1-phenylethane undergoes hydrolysis under basic conditions (such as sodium hydroxide aqueous solution), and bromine atoms are replaced by hydroxyl groups to obtain 1-phenylethanol. This is a nucleophilic substitution reaction. Hydroxide ions attack the carbon atoms connected to bromine as nucleophiles, and bromine ions leave.
After that, 1-phenylethanol is oxidized to phenylacetaldehyde under the action of appropriate oxidizing agents (such as isothermal and oxidizing agents of Sarit reagent). This reaction selectively oxidizes the alcohol hydroxyl group to the aldehyde group without affecting other structures such as the phenyl ring.
Then the phenylacetaldehyde and formaldehyde undergo a hydroxyaldehyde condensation reaction under the action of a basic catalyst (such as dilute sodium hydroxide solution) to generate 2-hydroxy-3-phenylpropanal. In this reaction, the α-hydrogen of phenylacetaldehyde leaves under the action of alkali to form carbon anions, which attack the carbonyl carbon of formaldehyde, and obtain the product through a series of processes.
Subsequently, 2-hydroxy-3-phenylpropionaldehyde reacts with hydrobromic acid, and the hydroxyl group is replaced by a bromine atom to form 2-bromo-3-phenylpropionaldehyde. This reaction is nucleophilic substitution, where bromine ions attack the carbon atom attached to the hydroxyl group, and the hydroxyl group leaves in the form of water.
Finally, 2-bromo-3-phenylpropionaldehyde is reduced under certain conditions (such as suitable reducing agent and reaction environment), and the aldehyde group is reduced to hydroxyethyl group, and the bromine atom on the benzene ring remains unchanged, and finally 1- (2-hydroxyethyl) -4-bromobenzene is obtained.
The synthesis process needs to be based on the characteristics of each step of the reaction, and the reaction conditions, such as temperature, pH, reactant ratio, etc., are precisely controlled to improve the reaction yield and selectivity and achieve the expected synthesis goal.
What are the market prospects for 1- (2-bromoethoxy) -4-chlorobenzene?
In today's world, the market prospect of 1- (2-hydroxyethyl) -4-nitrobenzene is quite popular. Looking at this substance, it has its uses in many fields.
In the field of medicine, it can be a key raw material for the synthesis of many drugs. Due to the rapid development of modern medicine, the demand for various specific drugs is increasing. Drugs made from this raw material may be effective for specific diseases. Therefore, the vigorous development of the pharmaceutical industry will bring a broad market to 1- (2-hydroxyethyl) -4-nitrobenzene. Pharmaceutical developers are constantly exploring new therapies and new prescriptions, and the demand for such raw materials is also increasing.
Furthermore, in the field of materials science, this substance also has potential. Today, the research and development of new materials is endless, and 1- (2-hydroxyethyl) -4-nitrobenzene may be involved in it, giving the material unique properties. For example, the synthesis of some high-performance polymer materials, if this substance is introduced, it may improve the stability and heat resistance of the material. With the advancement of science and technology, the demand for innovative ingredients in the field of materials continues, and this substance is expected to occupy a place in it.
However, although the market prospect is broad, there are also challenges. First, the production process may need to be refined. To expand the production scale and improve product quality, it is essential to optimize the production process. Second, the market competition is becoming increasingly fierce. As its application potential is recognized, many manufacturers may have to step in one after another. How to stand out in the competition needs to be thought deeply by producers.
To sum up, the 1- (2-hydroxyethyl) -4-nitrobenzene market has a bright future, but it also needs to deal with many challenges. Only by seizing the opportunity and responding actively can we win the favor of the market and seek long-term development.
In the field of medicine, it can be a key raw material for the synthesis of many drugs. Due to the rapid development of modern medicine, the demand for various specific drugs is increasing. Drugs made from this raw material may be effective for specific diseases. Therefore, the vigorous development of the pharmaceutical industry will bring a broad market to 1- (2-hydroxyethyl) -4-nitrobenzene. Pharmaceutical developers are constantly exploring new therapies and new prescriptions, and the demand for such raw materials is also increasing.
Furthermore, in the field of materials science, this substance also has potential. Today, the research and development of new materials is endless, and 1- (2-hydroxyethyl) -4-nitrobenzene may be involved in it, giving the material unique properties. For example, the synthesis of some high-performance polymer materials, if this substance is introduced, it may improve the stability and heat resistance of the material. With the advancement of science and technology, the demand for innovative ingredients in the field of materials continues, and this substance is expected to occupy a place in it.
However, although the market prospect is broad, there are also challenges. First, the production process may need to be refined. To expand the production scale and improve product quality, it is essential to optimize the production process. Second, the market competition is becoming increasingly fierce. As its application potential is recognized, many manufacturers may have to step in one after another. How to stand out in the competition needs to be thought deeply by producers.
To sum up, the 1- (2-hydroxyethyl) -4-nitrobenzene market has a bright future, but it also needs to deal with many challenges. Only by seizing the opportunity and responding actively can we win the favor of the market and seek long-term development.
What are the precautions for using 1- (2-bromoethoxy) -4-chlorobenzene?
1 - (2 -hydroxyethylamino) - 4 -chlorobenzene should pay attention to the following general matters during use:
First, it is related to safety protection. This compound may be toxic and irritating. When handling, be sure to wear suitable protective equipment, such as protective gloves, goggles and gas masks, to prevent skin contact, eye contamination and inhalation of dust or volatile gases. In case of inadvertent contact, rinse with plenty of water immediately and seek medical treatment according to specific conditions.
Second, about storage conditions. Store in a cool, dry and well-ventilated place, away from fire and heat sources. It should be stored separately from oxidants, acids, alkalis, etc., and should not be mixed to prevent dangerous chemical reactions. At the same time, the storage area should be equipped with suitable containment materials to deal with possible leaks.
Third, according to the operating specifications. The operation process should be carried out in a fume hood to ensure air circulation and reduce the risk of harmful gas accumulation. When taking reagents, precisely control the dosage to avoid waste and environmental pollution. Utensils after use should be cleaned in time to prevent residual substances from interfering with subsequent experiments or production.
Fourth, involving transportation links. Relevant regulations and standards should be followed during transportation to ensure that the packaging is complete and well sealed to prevent leakage during transportation. Transportation vehicles need to be equipped with corresponding firefighting equipment and emergency treatment equipment, and transportation personnel should also be familiar with the characteristics of the transported items and emergency treatment methods.
All these precautions need to be treated with caution to ensure the safety and efficiency of 1- (2-hydroxyethylamino) -4-chlorobenzene during use.
First, it is related to safety protection. This compound may be toxic and irritating. When handling, be sure to wear suitable protective equipment, such as protective gloves, goggles and gas masks, to prevent skin contact, eye contamination and inhalation of dust or volatile gases. In case of inadvertent contact, rinse with plenty of water immediately and seek medical treatment according to specific conditions.
Second, about storage conditions. Store in a cool, dry and well-ventilated place, away from fire and heat sources. It should be stored separately from oxidants, acids, alkalis, etc., and should not be mixed to prevent dangerous chemical reactions. At the same time, the storage area should be equipped with suitable containment materials to deal with possible leaks.
Third, according to the operating specifications. The operation process should be carried out in a fume hood to ensure air circulation and reduce the risk of harmful gas accumulation. When taking reagents, precisely control the dosage to avoid waste and environmental pollution. Utensils after use should be cleaned in time to prevent residual substances from interfering with subsequent experiments or production.
Fourth, involving transportation links. Relevant regulations and standards should be followed during transportation to ensure that the packaging is complete and well sealed to prevent leakage during transportation. Transportation vehicles need to be equipped with corresponding firefighting equipment and emergency treatment equipment, and transportation personnel should also be familiar with the characteristics of the transported items and emergency treatment methods.
All these precautions need to be treated with caution to ensure the safety and efficiency of 1- (2-hydroxyethylamino) -4-chlorobenzene during use.
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