Linshang Chemical
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Benzene,1,3-Bis(Chloromethyl)-
Linshang Chemical
|
HS Code |
543611 |
| Chemical Formula | C8H8Cl2 |
| Molar Mass | 175.055 g/mol |
| Appearance | White to off - white solid |
| Odor | Pungent |
| Density | 1.28 g/cm³ (approximate) |
| Melting Point | 90 - 94 °C |
| Boiling Point | 254 - 256 °C |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether |
| Flash Point | 127 °C |
| Vapor Pressure | Low vapor pressure at room temperature |
| Hazard Class | Corrosive, irritant |
As an accredited Benzene,1,3-Bis(Chloromethyl)- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 kg of 1,3 - bis(chloromethyl)benzene in sealed, chemical - resistant plastic drums. |
| Storage | **1,3 - Bis(chloromethyl)benzene Storage Description** 1,3 - Bis(chloromethyl)benzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition points. It must be kept in a tightly sealed container to prevent leakage, as it is potentially hazardous. Store it separately from oxidizing agents, bases, and moisture - sensitive materials to avoid chemical reactions. Also, ensure proper labeling for easy identification and safety. |
| Shipping | "1,3 - bis(chloromethyl)benzene" is a chemical. Shipping should comply with hazardous material regulations. It must be properly packaged, labeled, and transported by carriers authorized for such chemicals to ensure safety during transit. |
Competitive Benzene,1,3-Bis(Chloromethyl)- prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading Benzene,1,3-Bis(Chloromethyl)- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the chemical properties of 1,3-bis (chloromethyl) benzene?
1,3-Bis (chloromethyl) benzene is also an organic compound. It is active and has unique physicochemical properties.
Looking at its physical properties, it is a colorless to light yellow liquid under normal conditions, with a pungent odor. Its melting and boiling points vary depending on the intermolecular forces, and the boiling point is quite high. Due to factors such as intermolecular van der Waals forces and hydrogen bonds, it can only vaporize at relatively high temperatures. And its solubility in water is very small, because it is a non-polar organic molecule, and the forces between polar water molecules are weak, but it can be soluble in many organic solvents, such as ethanol, ether, etc., with similar compatibility.
In terms of its chemical properties, it is extremely active. The chloromethyl functional group in its molecule makes it possible to participate in a variety of chemical reactions. First, the nucleophilic substitution reaction, the halogen atom has a tendency to leave. When encountering a nucleophilic reagent, the nucleophilic reagent can attack the carbon atom, the halogen atom leaves, and form a new organic compound. For example, when reacted with sodium alcohol, the corresponding ether compounds can be formed. Second, the elimination reaction can occur. Under suitable alkali and conditions, the halogen atom is removed from the hydrogen atom on the adjacent carbon atom to form a carbon-carbon double bond to obtain an olefin compound. Third, because of its benzene ring structure, it can participate in the electrophilic substitution reaction of the benzene ring, such as halogenation, nitrification, sulfonation, etc. The electron cloud density distribution of the ben
However, it should be noted that 1,3-bis (chloromethyl) benzene is toxic and irritating. It can cause damage to human skin, eyes and respiratory tract. It is also difficult to degrade in the environment and can cause environmental pollution. Therefore, when using and handling, strict safety procedures should be followed to prevent harm to human body and the environment.
Looking at its physical properties, it is a colorless to light yellow liquid under normal conditions, with a pungent odor. Its melting and boiling points vary depending on the intermolecular forces, and the boiling point is quite high. Due to factors such as intermolecular van der Waals forces and hydrogen bonds, it can only vaporize at relatively high temperatures. And its solubility in water is very small, because it is a non-polar organic molecule, and the forces between polar water molecules are weak, but it can be soluble in many organic solvents, such as ethanol, ether, etc., with similar compatibility.
In terms of its chemical properties, it is extremely active. The chloromethyl functional group in its molecule makes it possible to participate in a variety of chemical reactions. First, the nucleophilic substitution reaction, the halogen atom has a tendency to leave. When encountering a nucleophilic reagent, the nucleophilic reagent can attack the carbon atom, the halogen atom leaves, and form a new organic compound. For example, when reacted with sodium alcohol, the corresponding ether compounds can be formed. Second, the elimination reaction can occur. Under suitable alkali and conditions, the halogen atom is removed from the hydrogen atom on the adjacent carbon atom to form a carbon-carbon double bond to obtain an olefin compound. Third, because of its benzene ring structure, it can participate in the electrophilic substitution reaction of the benzene ring, such as halogenation, nitrification, sulfonation, etc. The electron cloud density distribution of the ben
However, it should be noted that 1,3-bis (chloromethyl) benzene is toxic and irritating. It can cause damage to human skin, eyes and respiratory tract. It is also difficult to degrade in the environment and can cause environmental pollution. Therefore, when using and handling, strict safety procedures should be followed to prevent harm to human body and the environment.
What are the main uses of 1,3-bis (chloromethyl) benzene?
1,3-Bis (methoxy methyl) benzene, an organic compound, is widely used in the chemical industry. Its main uses are as follows:
First, it is used as an intermediate in organic synthesis. This compound has a unique structure. The two methoxy methyl groups on the benzene ring can be converted into other functional groups through many chemical reactions, and then a variety of organic compounds can be synthesized. For example, through substitution reactions, methoxy methyl groups can be replaced with other groups for the synthesis of fine chemicals, pharmaceutical intermediates, etc. Taking the synthesis of some drugs as an example, 1,3-bis (methoxy methyl) benzene can be used as a starting material to construct key structural fragments of drug molecules through a series of reactions.
Second, it is also used in the field of materials science. Due to its certain chemical stability and unique molecular structure, it can participate in the synthesis of polymer materials. For example, polymerization with other monomers generates polymer materials with special properties. These materials may exhibit unique properties in optics, electricity, heat, etc., and can be applied to the modification of coatings, plastics and other materials to improve the properties of materials.
Third, it also plays a role in the fragrance industry. Its special smell and chemical properties make it suitable for use as a fragrance component or in the synthesis of fragrances. It can endow fragrances with unique aroma characteristics and add a unique flavor to fragrance products. It is widely used in the preparation of perfumes, flavors and other products.
First, it is used as an intermediate in organic synthesis. This compound has a unique structure. The two methoxy methyl groups on the benzene ring can be converted into other functional groups through many chemical reactions, and then a variety of organic compounds can be synthesized. For example, through substitution reactions, methoxy methyl groups can be replaced with other groups for the synthesis of fine chemicals, pharmaceutical intermediates, etc. Taking the synthesis of some drugs as an example, 1,3-bis (methoxy methyl) benzene can be used as a starting material to construct key structural fragments of drug molecules through a series of reactions.
Second, it is also used in the field of materials science. Due to its certain chemical stability and unique molecular structure, it can participate in the synthesis of polymer materials. For example, polymerization with other monomers generates polymer materials with special properties. These materials may exhibit unique properties in optics, electricity, heat, etc., and can be applied to the modification of coatings, plastics and other materials to improve the properties of materials.
Third, it also plays a role in the fragrance industry. Its special smell and chemical properties make it suitable for use as a fragrance component or in the synthesis of fragrances. It can endow fragrances with unique aroma characteristics and add a unique flavor to fragrance products. It is widely used in the preparation of perfumes, flavors and other products.
What are the precautions for storing and transporting 1,3-bis (chloromethyl) benzene?
For 1% 2C3-bis (hydroxyethyl) naphthalene, many matters must be paid attention to during storage and transportation.
The first thing to pay attention to is its physical and chemical properties. This material may have specific chemical activity and physical properties. Only by knowing its melting point, boiling point, solubility, etc., can you know under what conditions it should be properly stored and transported. For example, if it is sensitive to temperature and easy to deteriorate at high temperature, it is necessary to avoid high temperature environment, choose a cool place for storage, and ensure that the temperature in the compartment is suitable when transporting.
The second is the important packaging. Be sure to choose suitable packaging materials to achieve the effect of sealing and leak-proof. Due to the reaction of 1% 2C3-bis (hydroxyethyl) naphthalene or with external substances, it can be tightly packed to avoid contact with air, moisture, etc. If it is packed in a special sealed container, it will prevent leakage and damage to the quality, and also avoid pollution to the surrounding environment.
Furthermore, the storage environment is critical. It should be placed in a dry and well-ventilated place, away from fire, heat and oxidants. Because of its flammability or the risk of reaction with oxidants, it will be dangerous if it is not careful. Warehouses need to have a complete ventilation system to disperse harmful gases that may accumulate.
When transporting, follow relevant regulations and operating procedures. Transport personnel should be professionally trained and familiar with the characteristics of this material and emergency treatment methods. Transportation vehicles need to be equipped with necessary emergency equipment and protective equipment, such as fire extinguishers, leakage emergency treatment tools, etc. On the way, it is also necessary to regularly check whether the packaging is in good condition to prevent accidents.
In summary, 1% 2C3-bis (hydroxyethyl) naphthalene is in storage and transportation, from characteristic cognition, packaging selection, environmental control to transportation specifications, every link cannot be ignored, so as to ensure its safe and stable circulation.
The first thing to pay attention to is its physical and chemical properties. This material may have specific chemical activity and physical properties. Only by knowing its melting point, boiling point, solubility, etc., can you know under what conditions it should be properly stored and transported. For example, if it is sensitive to temperature and easy to deteriorate at high temperature, it is necessary to avoid high temperature environment, choose a cool place for storage, and ensure that the temperature in the compartment is suitable when transporting.
The second is the important packaging. Be sure to choose suitable packaging materials to achieve the effect of sealing and leak-proof. Due to the reaction of 1% 2C3-bis (hydroxyethyl) naphthalene or with external substances, it can be tightly packed to avoid contact with air, moisture, etc. If it is packed in a special sealed container, it will prevent leakage and damage to the quality, and also avoid pollution to the surrounding environment.
Furthermore, the storage environment is critical. It should be placed in a dry and well-ventilated place, away from fire, heat and oxidants. Because of its flammability or the risk of reaction with oxidants, it will be dangerous if it is not careful. Warehouses need to have a complete ventilation system to disperse harmful gases that may accumulate.
When transporting, follow relevant regulations and operating procedures. Transport personnel should be professionally trained and familiar with the characteristics of this material and emergency treatment methods. Transportation vehicles need to be equipped with necessary emergency equipment and protective equipment, such as fire extinguishers, leakage emergency treatment tools, etc. On the way, it is also necessary to regularly check whether the packaging is in good condition to prevent accidents.
In summary, 1% 2C3-bis (hydroxyethyl) naphthalene is in storage and transportation, from characteristic cognition, packaging selection, environmental control to transportation specifications, every link cannot be ignored, so as to ensure its safe and stable circulation.
What are the synthesis methods of 1,3-bis (chloromethyl) benzene?
There are several common methods for the synthesis of 1% 2C3-bis (methoxymethyl) benzene:
First, benzene is used as the starting material through Fu-gram alkylation reaction. The benzene and chloromethyl methyl ether are first reacted under the catalysis of Lewis acid (such as anhydrous aluminum trichloride). In this process, Lewis acid activates chloromethyl methyl ether to generate carbon positive ions, which then undergoes electrophilic substitution reaction with the phenyl ring, and methoxymethyl is introduced into the phenyl ring. Attention should be paid to the control of the reaction conditions. The reaction temperature should not be too high to avoid the generation of multiple substitution by-products. After the reaction is completed, the target product can be obtained through hydrolysis, separation, purification and other steps. The raw materials of this method are easy to obtain, but the reaction selectivity is not good, and the post-treatment is slightly
Second, organometallic reagents can be used. Bromobenzene is used as raw material to prepare Grignard reagent (bromobenzene and magnesium react in anhydrous ether to obtain phenyl magnesium bromide). Subsequently, the Grignard reagent is reacted with methoxy methyl halide (such as methoxy methyl chloride). The reaction can introduce methoxy methyl at a specific position in the benzene ring with better selectivity. However, the preparation of Grignard reagents requires strict anhydrous and oxygen-free conditions, which requires high operation requirements. And organic metal reagents have high activity, so special caution is required when storing and using.
Third, palladium-catalyzed coupling reaction is used. For example, phenylboronic acid and halomethoxylmethane (such as chloromethoxylmethane) are used as raw materials, and the reaction is carried out in the presence of palladium catalysts (such as tetra (triphenylphosphine) palladium) and bases (such as potassium carbonate). This method has mild conditions, excellent selectivity, and strong adaptability to substrates. However, palladium catalysts are expensive, costly, and difficult to separate and recover catalysts after the reaction, which limits their large-scale application to a certain extent.
First, benzene is used as the starting material through Fu-gram alkylation reaction. The benzene and chloromethyl methyl ether are first reacted under the catalysis of Lewis acid (such as anhydrous aluminum trichloride). In this process, Lewis acid activates chloromethyl methyl ether to generate carbon positive ions, which then undergoes electrophilic substitution reaction with the phenyl ring, and methoxymethyl is introduced into the phenyl ring. Attention should be paid to the control of the reaction conditions. The reaction temperature should not be too high to avoid the generation of multiple substitution by-products. After the reaction is completed, the target product can be obtained through hydrolysis, separation, purification and other steps. The raw materials of this method are easy to obtain, but the reaction selectivity is not good, and the post-treatment is slightly
Second, organometallic reagents can be used. Bromobenzene is used as raw material to prepare Grignard reagent (bromobenzene and magnesium react in anhydrous ether to obtain phenyl magnesium bromide). Subsequently, the Grignard reagent is reacted with methoxy methyl halide (such as methoxy methyl chloride). The reaction can introduce methoxy methyl at a specific position in the benzene ring with better selectivity. However, the preparation of Grignard reagents requires strict anhydrous and oxygen-free conditions, which requires high operation requirements. And organic metal reagents have high activity, so special caution is required when storing and using.
Third, palladium-catalyzed coupling reaction is used. For example, phenylboronic acid and halomethoxylmethane (such as chloromethoxylmethane) are used as raw materials, and the reaction is carried out in the presence of palladium catalysts (such as tetra (triphenylphosphine) palladium) and bases (such as potassium carbonate). This method has mild conditions, excellent selectivity, and strong adaptability to substrates. However, palladium catalysts are expensive, costly, and difficult to separate and recover catalysts after the reaction, which limits their large-scale application to a certain extent.
What are the effects of 1,3-bis (chloromethyl) benzene on the environment and human health?
1,3-Bis (methoxymethyl) benzene, the impact of this substance on the environment and human health needs to be carefully reviewed.
As far as the environment is concerned, its degradation process in the natural environment is quite slow. If it accidentally enters the water body, it will float on the water surface because it is insoluble in water and slightly less dense than water, hindering the gas exchange between the water body and the atmosphere, resulting in a decrease in the amount of dissolved oxygen in the water, endangering the survival of aquatic organisms. It may also be adsorbed on suspended particulate matter and settle to the bottom of the water, causing damage to the habitat of benthic organisms. In soil, it will inhibit the activity of soil microorganisms, interfere with the material cycle and energy conversion of the soil ecosystem, and in the long run, it may reduce soil fertility and affect vegetation growth.
As for human health, it has a certain volatility. When the concentration in the air is too high, it will be the first to irritate the respiratory mucosa after inhalation, causing symptoms such as cough, asthma, and breathing difficulties. If exposed for a long time, it may also cause damage to the nervous system, causing people to experience dizziness, headache, fatigue, memory loss and other neurasthenia-like manifestations. At the same time, percutaneous contact should not be underestimated. It may enter the human body through the skin barrier, causing irritation to the skin, causing allergic reactions such as redness, swelling, itching, and rash. More serious cases, based on relevant toxicological studies, it is speculated that it may have potential carcinogenicity. Although there is no conclusive evidence of human carcinogenicity, animal experiments have shown a certain tendency to cause cancer. This point should be particularly vigilant. Therefore, whether it is to protect the sustainable development of the environment or to protect the health and well-being of the human body, the use and emission of 1,3-bis (methoxymethyl) benzene should be strictly regulated and controlled.
As far as the environment is concerned, its degradation process in the natural environment is quite slow. If it accidentally enters the water body, it will float on the water surface because it is insoluble in water and slightly less dense than water, hindering the gas exchange between the water body and the atmosphere, resulting in a decrease in the amount of dissolved oxygen in the water, endangering the survival of aquatic organisms. It may also be adsorbed on suspended particulate matter and settle to the bottom of the water, causing damage to the habitat of benthic organisms. In soil, it will inhibit the activity of soil microorganisms, interfere with the material cycle and energy conversion of the soil ecosystem, and in the long run, it may reduce soil fertility and affect vegetation growth.
As for human health, it has a certain volatility. When the concentration in the air is too high, it will be the first to irritate the respiratory mucosa after inhalation, causing symptoms such as cough, asthma, and breathing difficulties. If exposed for a long time, it may also cause damage to the nervous system, causing people to experience dizziness, headache, fatigue, memory loss and other neurasthenia-like manifestations. At the same time, percutaneous contact should not be underestimated. It may enter the human body through the skin barrier, causing irritation to the skin, causing allergic reactions such as redness, swelling, itching, and rash. More serious cases, based on relevant toxicological studies, it is speculated that it may have potential carcinogenicity. Although there is no conclusive evidence of human carcinogenicity, animal experiments have shown a certain tendency to cause cancer. This point should be particularly vigilant. Therefore, whether it is to protect the sustainable development of the environment or to protect the health and well-being of the human body, the use and emission of 1,3-bis (methoxymethyl) benzene should be strictly regulated and controlled.
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