Benzene, 1-Bromo-2-Chloro-4-Methoxy-

Linshang Chemical

Specifications

HS Code

681286

Name Benzene, 1 - Bromo - 2 - Chloro - 4 - Methoxy -
Molecular Formula C7H6BrClO
Molecular Weight 221.48
Appearance Typically a solid (physical state depends on conditions)
Solubility Likely sparingly soluble in water, more soluble in organic solvents like ethanol, ether
Vapor Pressure Low vapor pressure, being a relatively non - volatile compound
Hazard Class May be harmful if swallowed, inhaled or in contact with skin; potentially irritant

As an accredited Benzene, 1-Bromo-2-Chloro-4-Methoxy- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1 - bromo - 2 - chloro - 4 - methoxy - benzene in a sealed chemical - resistant bottle.
Storage Store "Benzene, 1 - bromo - 2 - chloro - 4 - methoxy -" in a cool, well - ventilated area away from heat, sparks, and open flames. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials like glass. Separate it from oxidizing agents and reactive substances. Ensure proper labeling for easy identification and safety compliance.
Shipping Benzene, 1 - bromo - 2 - chloro - 4 - methoxy - should be shipped in accordance with hazardous chemical regulations. Use proper, sealed containers to prevent leakage, and ensure compliance with transportation safety and environmental protection requirements.
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Benzene, 1-Bromo-2-Chloro-4-Methoxy- Benzene, 1-Bromo-2-Chloro-4-Methoxy-
General Information
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Frequently Asked Questions

As a leading Benzene, 1-Bromo-2-Chloro-4-Methoxy- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 1-bromo-2-chloro-4-methoxybenzene?
The chemical properties of 1 + -mercury-2-bromo-4-methoxyphenyl are as follows:
Mercury, a highly toxic metal element, is a liquid at room temperature and is volatile. Its chemical properties are relatively active, and it can form amalgams with many metals, and can also react with non-metals such as oxygen and sulfur. Under certain conditions, mercury can participate in redox reactions to change its own valence state. For example, when mercury is heated with oxygen, mercury oxide will be formed.
Bromine, a reddish-brown smoky liquid, has a strong pungent odor. Bromine is chemically active and is a strong oxidant. It can directly combine with many metals and non-metals. When reacting with metals, the metal will be oxidized to the corresponding bromide; when reacting with non-metals, such as with hydrogen under heating or light conditions, hydrogen bromide can be generated. At the same time, bromine will undergo a disproportionation reaction in water to generate hydrobromic acid and hypobromic acid.
4 -methoxyphenyl, as an organic group, has unique properties due to the presence of methoxy groups. Methoxy is the power supply group, which can increase the electron cloud density on the benzene ring, thereby enhancing the nucleophilicity of the benzene ring, making the compounds where the group is located more prone to electrophilic substitution reactions, such as halogenation, nitrification, sulfonation, etc. Under appropriate conditions, the methoxy group in 4-methoxyphenyl can be replaced by other groups, or various functional group conversion reactions occur on the benzene ring, resulting in the derivation of a variety of organic compounds.
These three have different chemical properties and play unique roles in the fields of chemical reactions and substance preparation, participating in many important chemical processes and substance transformation.
What are the applications of 1-bromo-2-chloro-4-methoxybenzene in organic synthesis?
1 + -Hydroxy-2-aldehyde-4-methoxybenzyl is a widely used raw material in organic synthesis. This compound can emerge and play a key role in many organic reactions.
First, in the nucleophilic substitution reaction, 1 + -hydroxyl-2-aldehyde-4-methoxybenzyl can be used as a nucleophilic reagent to react with substrates such as halogenated hydrocarbons due to its unique structure. In this process, functional groups such as hydroxyl, aldehyde and methoxy cooperate with each other, so that the reaction can be smoothly advanced to generate a series of organic products with specific structures and functions. For example, the presence of aldehyde groups can enhance the nucleophilic activity of compounds and guide the reaction in the desired direction.
Second, in the field of condensation reactions, the aldehyde group of 1 + -hydroxy- 2-aldehyde-4-methoxybenzyl can react with compounds containing active hydrogen, such as amines and alcohols. Through such reactions, more complex organic molecular structures can be constructed to form chemical bonds such as carbon-nitrogen or carbon-oxygen, thereby expanding the types and functions of organic compounds. For example, condensation with amines can generate Schiff bases with potential biological activities.
Furthermore, in the redox reaction, 1 + -hydroxyl-2-aldehyde-4-methoxybenzyl can also act as a reactant. The aldehyde group can be oxidized to a carboxyl group or reduced to an alcohol hydroxyl group under specific conditions. This redox property provides a diverse approach for organic synthesis, which can flexibly adjust the functional groups of compounds to meet the needs of different synthesis targets.
In addition, the methoxy group of 1 + -hydroxyl-2-aldehyde-4-methoxybenzyl can undergo demethylation under certain conditions, and then introduce new functional groups, creating opportunities for the modification and modification of organic molecules. In the synthesis of many complex natural products or drug molecules, such reaction steps are often used to achieve the gradual construction and optimization of molecular structures.
1 + -hydroxyl-2-aldehyde-4-methoxybenzyl is like a shining star in the field of organic synthesis. It has shown value that cannot be ignored in many reactions such as nucleophilic substitution, condensation, redox and functional group transformation, opening up a broad path for the creation and research and development of organic compounds.
What is the preparation method of 1-bromo-2-chloro-4-methoxybenzene?
To prepare 1-bromo-2-chloro-4-methoxybenzene, the method is as follows:
First take an appropriate amount of methoxybenzene and place it in a clean reactor. Under low temperature and stirring state, slowly add specific reagents containing bromine and chlorine. This process requires strict temperature control to make the reaction proceed smoothly. For the addition of bromine and chlorine, a suitable catalyst needs to be selected to promote the efficient occurrence of the reaction. The catalyst used should be carefully selected according to the specific situation of the reaction, or it should be a metal halide or the like.
The speed of dropwise addition should be adjusted flexibly according to the reaction process, and it should not be too fast to prevent the reaction from being too violent and causing runaway. After the dropwise addition is completed, maintain a certain temperature and continue to stir to make the reaction sufficient. During this period, the degree of reaction needs to be monitored regularly, and the ratio of reactants to products can be carefully observed by analytical means such as chromatography.
When the reaction is almost complete, pour the reaction mixture into an appropriate amount of solvent to extract and separate the product. The solvent used, when the product has good solubility, is easy to separate from other components in the reaction system. After extraction, the impurities are removed through purification steps such as distillation and recrystallization to obtain pure 1-bromo-2-chloro-4-methoxybenzene. During distillation, pay attention to the regulation of temperature and pressure to effectively separate the product. The recrystallization process also requires careful selection of solvents and operating conditions to obtain a high-purity crystalline product.
The entire preparation process is crucial to controlling the reaction conditions, from the temperature, the amount of catalyst, to the details of each step, all affect the yield and purity of the product. A little poor pooling may lead to impurity or low yield of the product.
What are the physical properties of 1-bromo-2-chloro-4-methoxybenzene?
The physical properties of 1 + -ether-2-alkane-4-methoxybenzyl are as follows:
Under normal conditions, this substance is either a clear and transparent liquid or a white and delicate solid form, which is closely related to its intermolecular interactions and structure. Its melting point is an important indicator for measuring the transformation of the substance from solid to liquid. Under specific conditions, when the temperature rises to a certain exact value, the thermal motion of the molecule intensifies, the lattice structure disintegrates, and the phase transition occurs.
Looking at its boiling point, under a specific pressure environment, the molecules of the substance obtain enough energy to overcome the intermolecular forces and transform from liquid to gas. At this time, the temperature is the boiling point. This property is of great significance for the separation and purification of the substance.
When it comes to density, it is the mass of the substance per unit volume, which reflects the degree of compactness of the arrangement of particles inside the substance. The density of this substance is similar to that of common organic solvents, and may be similar or different. In chemical practice, it can be used to achieve separation, delamination and other operations related to it.
In terms of solubility, this substance exhibits good solubility in organic solvents such as ethanol and ether by virtue of the principle of similar miscibility, and can be uniformly dispersed to form a uniform and stable solution. However, in water, due to the large difference in molecular polarity from water molecules, it is difficult to form effective intermolecular forces, so the solubility is very poor.
In addition, the refractive index of this substance is also one of the important physical properties. When light passes through this substance, the propagation direction changes, and the refractive index can accurately characterize this property. It has important application value in optical materials, analysis and testing, etc. Its appearance may vary slightly due to factors such as purity and preparation method. Pure products are usually relatively pure and uniform, and the presence of impurities may affect their apparent characteristics such as color and crystal form.
What are the market prospects for 1-bromo-2-chloro-4-methoxybenzene?
In today's world, the market prospects of "1 + -ether-2 + -alkane-4 + -methoxybenzyl" are worth exploring.
Looking at this industry, one is that with the advance of science and technology, the demand for it is gradually increasing in various fields of medicine. In the way of pharmaceutical synthesis, "1 + -ether-2 + -alkane-4 + -methoxybenzyl" is often a key raw material. Physicians seek new drug development, and this material is the cornerstone. If a specific drug molecule is synthesized, it may be the starting substance, so the pharmaceutical industry will thrive, and its demand will increase.
Second, the chemical industry also depends on it. Chemical products are diverse, the manufacture of coatings, plastics, etc., "1 + -ether-2 + -alkane-4 + -methoxybenzyl" or involved, can be modified additives, improve the properties of products, such as firmness, toughness, weather resistance, etc. With the rise of chemical industry, the industry has expanded and production capacity has increased, and the demand for it has also become wider.
However, its market situation also poses challenges. The source of raw materials is related to the stability of cost and supply. If the production of raw materials changes, prices or fluctuations, the operation of the industry will also be disturbed. And the competition in the same industry will be fierce, and everyone will compete for the market, and they must compete for quality and price. If you want to take the lead, you need to refine the process, reduce costs and improve quality, and you can only last for a long time.
And the regulation of the market is becoming stricter, and the regulations of environmental protection and safety must be followed by the industry. If you violate it, the penalty will come, and the industry will also be frustrated. It is based on the industry's supervision and regulations, and based on compliance, the industry will move forward.
Overall, "1 + -ether-2 + -alkane-4 + -methoxybenzyl" in today's city, opportunities and challenges coexist. Those who are good at observing the situation, fine craftsmanship, and compliance will surely be able to win a place in the market and expand a bright future.