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Benzene, 1-(Bromomethyl)-2-Chloro-3-Fluoro-
Linshang Chemical
|
HS Code |
604030 |
| Chemical Formula | C7H5BrClF |
| Molecular Weight | 225.47 |
| Appearance | Typically a colorless to light - colored liquid or solid (dependent on conditions) |
| Boiling Point | Estimated based on similar compounds, likely in the range of 200 - 250°C (approximate) |
| Density | Estimated density around 1.6 - 1.8 g/cm³ (approximate, based on halogen - benzene derivatives) |
| Solubility In Water | Low solubility in water, due to non - polar benzene ring and hydrophobic nature of halogen and bromomethyl groups |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform, ethyl acetate |
| Vapor Pressure | Low vapor pressure at room temperature, as it is a relatively high - molecular - weight and non - volatile compound |
| Flash Point | Estimated flash point above 100°C (approximate, as it contains halogen atoms which increase flash point) |
As an accredited Benzene, 1-(Bromomethyl)-2-Chloro-3-Fluoro- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100 - gram bottle of 1-(bromomethyl)-2 - chloro - 3 - fluorobenzene, securely sealed. |
| Storage | Store "Benzene, 1-(bromomethyl)-2-chloro-3-fluoro-" in a cool, well - ventilated area away from heat, ignition sources, and incompatible substances. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials like glass or specific plastics. Avoid storing near oxidizing agents, strong acids, or bases due to potential reactivity. |
| Shipping | Ship "1-(Bromomethyl)-2-chloro-3-fluoro - benzene" in well - sealed, corrosion - resistant containers. Follow all hazardous chemical shipping regulations, ensuring proper labeling and documentation for safe transport. |
Competitive Benzene, 1-(Bromomethyl)-2-Chloro-3-Fluoro- prices that fit your budget—flexible terms and customized quotes for every order.
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What are the physical properties of this compound 1- (bromomethyl) -2-chloro-3-fluorobenzene
1- (benzyl) -2-chloro-3-bromobenzene is a common compound in chemical synthesis. This compound has unique physical properties, which are related to its application and treatment methods.
It is mostly solid at room temperature and has high stability. Due to the interaction of benzyl, chlorine and bromine atoms in its molecular structure, a relatively stable chemical structure is formed. Melting point and boiling point are key physical parameters. The melting point is about [X] ° C, and the boiling point is about [X] ° C. This property allows it to maintain a solid state within a specific temperature range, making it easy to store and transport.
In terms of solubility, the compound is difficult to dissolve in water. Due to the fact that water molecules are polar molecules, while 1- (benzyl) -2-chloro-3-bromobenzene molecules have weaker polarity, according to the principle of "similarity and miscibility", the two are difficult to miscible. However, it is soluble in a variety of organic solvents, such as ether, dichloromethane, etc. In organic synthesis reactions, such organic solvents are often selected as reaction media, and the co-compounds are uniformly dispersed to promote the smooth progress of the reaction.
Density is also an important physical property. Its density is greater than that of water, about [X] g/cm ³. This property is of great significance in experimental or industrial processes involving operations such as stratification. If the product is separated after the reaction, if mixed with water, the compound will settle in the bottom of the water, which is conducive to separation by means of liquid
In addition, the compound is volatile to a certain extent. Although the volatility is not strong, it may affect human health if exposed to it for a long time in a poorly ventilated environment. Therefore, when operating and storing, it is necessary to ensure that the environment is well ventilated to ensure safety.
It is mostly solid at room temperature and has high stability. Due to the interaction of benzyl, chlorine and bromine atoms in its molecular structure, a relatively stable chemical structure is formed. Melting point and boiling point are key physical parameters. The melting point is about [X] ° C, and the boiling point is about [X] ° C. This property allows it to maintain a solid state within a specific temperature range, making it easy to store and transport.
In terms of solubility, the compound is difficult to dissolve in water. Due to the fact that water molecules are polar molecules, while 1- (benzyl) -2-chloro-3-bromobenzene molecules have weaker polarity, according to the principle of "similarity and miscibility", the two are difficult to miscible. However, it is soluble in a variety of organic solvents, such as ether, dichloromethane, etc. In organic synthesis reactions, such organic solvents are often selected as reaction media, and the co-compounds are uniformly dispersed to promote the smooth progress of the reaction.
Density is also an important physical property. Its density is greater than that of water, about [X] g/cm ³. This property is of great significance in experimental or industrial processes involving operations such as stratification. If the product is separated after the reaction, if mixed with water, the compound will settle in the bottom of the water, which is conducive to separation by means of liquid
In addition, the compound is volatile to a certain extent. Although the volatility is not strong, it may affect human health if exposed to it for a long time in a poorly ventilated environment. Therefore, when operating and storing, it is necessary to ensure that the environment is well ventilated to ensure safety.
What are the chemical properties of 1- (bromomethyl) -2-chloro-3-fluorobenzene?
(Alkyl methyl), a group in organic chemistry. This group is stable in nature and often exists in various organic compounds.
As for bromine, it is one of the halogen elements. Its elemental substance is a dark reddish-brown liquid at room temperature, volatile and has a strong pungent odor. Bromine is chemically active and can react with many substances. For example, it can react with metal elementals to form metal bromides; it can also react with some organic compounds such as substitution and addition.
Alkynes and the like have the characteristics of both alkenes and alkynes. Olefins contain carbon-carbon double bonds, and alkynes contain carbon-carbon triple bonds, which give alkynes unique chemical properties. Alyne can undergo addition reactions, such as with hydrogen, halogens, hydrogen halides, etc., and generate different products according to the reaction conditions and the proportion of reactants. Alyne can also undergo oxidation reactions. For example, under the action of appropriate oxidants, carbon-carbon double bonds or triple bonds can be oxidized and broken to form different oxidation products such as alcaldes, ketones, and carboxylic acids. In addition, alkynne can still participate in polymerization reactions to form polymer compounds. Because of its unsaturated bonds, alkynne is relatively active in chemical properties and has a wide range of uses in the field of organic synthesis. It can be used as a raw material to synthesize many complex organic compounds.
As for bromine, it is one of the halogen elements. Its elemental substance is a dark reddish-brown liquid at room temperature, volatile and has a strong pungent odor. Bromine is chemically active and can react with many substances. For example, it can react with metal elementals to form metal bromides; it can also react with some organic compounds such as substitution and addition.
Alkynes and the like have the characteristics of both alkenes and alkynes. Olefins contain carbon-carbon double bonds, and alkynes contain carbon-carbon triple bonds, which give alkynes unique chemical properties. Alyne can undergo addition reactions, such as with hydrogen, halogens, hydrogen halides, etc., and generate different products according to the reaction conditions and the proportion of reactants. Alyne can also undergo oxidation reactions. For example, under the action of appropriate oxidants, carbon-carbon double bonds or triple bonds can be oxidized and broken to form different oxidation products such as alcaldes, ketones, and carboxylic acids. In addition, alkynne can still participate in polymerization reactions to form polymer compounds. Because of its unsaturated bonds, alkynne is relatively active in chemical properties and has a wide range of uses in the field of organic synthesis. It can be used as a raw material to synthesize many complex organic compounds.
In which chemical reactions does 1- (bromomethyl) -2-chloro-3-fluorobenzene act as a reactant?
Among many chemical echoes, cyanomethyl, cyanide, and nitrile substances often act as echoes, intervening in various chemical changes, and showing key uses in organic synthesis.
Let's talk about cyanomethyl first, which contains highly active functional groups in its layout. In the nucleophilic substitution echo, cyanomethyl can attack other molecules containing electrophilic centers by virtue of the nucleophilicity of carbon atoms. For example, when nucleophilic substitution occurs with halogenated hydrocarbons, halogen atoms are replaced by cyanomethyl groups to form new compounds containing cyanyl groups. This is a key way to grow the carbon chain and introduce cyanyl groups. Cyanyl groups can also be converted into carboxyl groups and other functional groups through reactions such as hydrolysis.
Cyanide ($CN_2 $) is active and is common in some redox reactions or complexation reactions with metal ions. Cyanide can be used as a ligand to complex with metal ions to form stable complexes and change the chemical and physical properties of metal ions. In some specific organic synthesis reactions, cyanide can also be used as a special reaction reagent to participate in the construction of complex organic molecular structures.
Nitrile substances have $C ≡ N $triple bonds, which give nitriles unique reactivity. In the hydrolysis reaction, nitriles are gradually converted into amides under the catalysis of acids or bases, and then carboxylic acids are formed; nitriles can also be reduced to amine compounds in the reduction reaction, which is a key step in the process of organic synthesis to produce nitrogen-containing organic compounds. For example, acetonitrile can be hydrolyzed to produce acetic acid under specific conditions, and ethylamine can be obtained by reduction.
In summary, cyanomethyl, cyanide, and nitrile substances play a key role in many chemical reactions, especially in organic synthesis, due to their unique structures and properties, and help to build a rich variety of organic compounds, promoting the continuous development of the field of organic chemistry.
Let's talk about cyanomethyl first, which contains highly active functional groups in its layout. In the nucleophilic substitution echo, cyanomethyl can attack other molecules containing electrophilic centers by virtue of the nucleophilicity of carbon atoms. For example, when nucleophilic substitution occurs with halogenated hydrocarbons, halogen atoms are replaced by cyanomethyl groups to form new compounds containing cyanyl groups. This is a key way to grow the carbon chain and introduce cyanyl groups. Cyanyl groups can also be converted into carboxyl groups and other functional groups through reactions such as hydrolysis.
Cyanide ($CN_2 $) is active and is common in some redox reactions or complexation reactions with metal ions. Cyanide can be used as a ligand to complex with metal ions to form stable complexes and change the chemical and physical properties of metal ions. In some specific organic synthesis reactions, cyanide can also be used as a special reaction reagent to participate in the construction of complex organic molecular structures.
Nitrile substances have $C ≡ N $triple bonds, which give nitriles unique reactivity. In the hydrolysis reaction, nitriles are gradually converted into amides under the catalysis of acids or bases, and then carboxylic acids are formed; nitriles can also be reduced to amine compounds in the reduction reaction, which is a key step in the process of organic synthesis to produce nitrogen-containing organic compounds. For example, acetonitrile can be hydrolyzed to produce acetic acid under specific conditions, and ethylamine can be obtained by reduction.
In summary, cyanomethyl, cyanide, and nitrile substances play a key role in many chemical reactions, especially in organic synthesis, due to their unique structures and properties, and help to build a rich variety of organic compounds, promoting the continuous development of the field of organic chemistry.
What are the synthesis methods of 1- (bromomethyl) -2-chloro-3-fluorobenzene?
If you want to make hydroxymethyl, cyanogen and allyl, there are many methods, which are described in detail today.
The common method for making hydroxymethyl is to react with formaldehyde and the corresponding substrate. If the substrate is an active hydrogen compound, such as alcohol, phenol, etc., in the presence of an appropriate catalyst, the nucleophilic addition reaction can occur between the two. Take methanol as an example. When the alkaline catalyst acts, the carbonyl carbon of formaldehyde is electrophilic, and the lone pair electron on the oxygen atom of methanol attacks the carbonyl carbon, thereby forming hydroxymethyl ether compounds. This reaction condition is mild and easy to control, but it is necessary to precisely control the catalyst dosage and reaction temperature to prevent overreaction.
As for the synthesis of cyanide, it is often obtained by reacting a nitrogen-containing compound with a carbon-containing compound. The classical method is to react ammonia and methane at high temperature and under specific catalyst conditions. The nitrogen atom in ammonia combines with the carbon atom of methane and goes through a complex reaction process to form hydrogen cyanide. This process requires high temperature environment, strict equipment requirements, and fine operation is required for product separation and purification to obtain high-purity cyanide.
The preparation of allyl can be achieved by the elimination reaction of halogenated hydrocarbons. Such as allyl halide, under the action of strong base, the halogen atom is removed from the hydrogen atom on the adjacent carbon atom to form a carbon-carbon double bond to form an allyl compound. Second, the dehydration reaction of alcohol can be used. Under the action of an appropriate dehydrating agent, allyl alcohol removes a molecule of water from the molecule to form an allyl structure. These two methods have their own advantages and disadvantages. To eliminate the reaction, a suitable strong base and reaction conditions need to be selected to prevent side reactions; the dehydration reaction requires quite high activity and selectivity of the dehydrating agent.
All these synthesis methods need to be carefully selected according to actual needs, weighing factors such as reaction conditions, cost, yield and product purity, etc., to achieve the ideal synthesis effect.
The common method for making hydroxymethyl is to react with formaldehyde and the corresponding substrate. If the substrate is an active hydrogen compound, such as alcohol, phenol, etc., in the presence of an appropriate catalyst, the nucleophilic addition reaction can occur between the two. Take methanol as an example. When the alkaline catalyst acts, the carbonyl carbon of formaldehyde is electrophilic, and the lone pair electron on the oxygen atom of methanol attacks the carbonyl carbon, thereby forming hydroxymethyl ether compounds. This reaction condition is mild and easy to control, but it is necessary to precisely control the catalyst dosage and reaction temperature to prevent overreaction.
As for the synthesis of cyanide, it is often obtained by reacting a nitrogen-containing compound with a carbon-containing compound. The classical method is to react ammonia and methane at high temperature and under specific catalyst conditions. The nitrogen atom in ammonia combines with the carbon atom of methane and goes through a complex reaction process to form hydrogen cyanide. This process requires high temperature environment, strict equipment requirements, and fine operation is required for product separation and purification to obtain high-purity cyanide.
The preparation of allyl can be achieved by the elimination reaction of halogenated hydrocarbons. Such as allyl halide, under the action of strong base, the halogen atom is removed from the hydrogen atom on the adjacent carbon atom to form a carbon-carbon double bond to form an allyl compound. Second, the dehydration reaction of alcohol can be used. Under the action of an appropriate dehydrating agent, allyl alcohol removes a molecule of water from the molecule to form an allyl structure. These two methods have their own advantages and disadvantages. To eliminate the reaction, a suitable strong base and reaction conditions need to be selected to prevent side reactions; the dehydration reaction requires quite high activity and selectivity of the dehydrating agent.
All these synthesis methods need to be carefully selected according to actual needs, weighing factors such as reaction conditions, cost, yield and product purity, etc., to achieve the ideal synthesis effect.
What are the main uses of 1- (bromomethyl) -2-chloro-3-fluorobenzene?
Ether group, a class of functional groups in organic compounds. It often has stable chemical properties and is very important in the field of organic synthesis.
Cyanyl group, a group connected by a triple bond between carbon and nitrogen. It has a wide range of uses and is indispensable in pharmaceuticals, dye synthesis, etc. Among nitriles, the presence of cyanyl groups gives it unique chemical activity, which can participate in a variety of chemical reactions, such as hydrolysis, reduction, etc., and then prepare various important organic compounds.
Ether has many main uses. First, it is used as an organic solvent. Because of its good solubility to many organic compounds, and its moderate boiling point and volatility, such as ether, it is often used in laboratories and industrial production to extract organic substances and dissolve reactants. Second, in the field of organic synthesis, it is a key intermediate. Through Williamson synthesis, etc., ether compounds with different structures can be prepared, and then complex organic molecules can be synthesized. Third, in medicinal chemistry, some drugs containing ether structures have specific pharmacological activities. For example, in some narcotic drugs, ether structures help drugs pass through biofilms and exert their medicinal effects. Fourth, in the field of polymer materials, some polyether polymers can be prepared with excellent properties due to their good flexibility and stability. Elastomers, engineering plastics, etc. are widely used in automotive, electronics and other industries.
Cyanyl group, a group connected by a triple bond between carbon and nitrogen. It has a wide range of uses and is indispensable in pharmaceuticals, dye synthesis, etc. Among nitriles, the presence of cyanyl groups gives it unique chemical activity, which can participate in a variety of chemical reactions, such as hydrolysis, reduction, etc., and then prepare various important organic compounds.
Ether has many main uses. First, it is used as an organic solvent. Because of its good solubility to many organic compounds, and its moderate boiling point and volatility, such as ether, it is often used in laboratories and industrial production to extract organic substances and dissolve reactants. Second, in the field of organic synthesis, it is a key intermediate. Through Williamson synthesis, etc., ether compounds with different structures can be prepared, and then complex organic molecules can be synthesized. Third, in medicinal chemistry, some drugs containing ether structures have specific pharmacological activities. For example, in some narcotic drugs, ether structures help drugs pass through biofilms and exert their medicinal effects. Fourth, in the field of polymer materials, some polyether polymers can be prepared with excellent properties due to their good flexibility and stability. Elastomers, engineering plastics, etc. are widely used in automotive, electronics and other industries.
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