Linshang Chemical
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Benzene, 1-(Bromomethyl)-2-Chloro-3-(Trifluoromethyl)-
Linshang Chemical
|
HS Code |
925234 |
| Chemical Formula | C8H5BrClF3 |
| Molar Mass | 289.48 g/mol |
As an accredited Benzene, 1-(Bromomethyl)-2-Chloro-3-(Trifluoromethyl)- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100 g of 1-(bromomethyl)-2 -chloro-3-(trifluoromethyl)benzene in a sealed chemical - grade bottle. |
| Storage | Store “Benzene, 1-(bromomethyl)-2 -chloro-3-(trifluoromethyl)-” in a cool, well - ventilated area, away from heat, sparks, and open flames due to its potential flammability. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials, to prevent leakage and contact with air or moisture which could cause reactions. Separate from oxidizing agents and incompatible substances. |
| Shipping | The chemical "Benzene, 1-(bromomethyl)-2-chloro-3-(trifluoromethyl)-" should be shipped in accordance with strict hazardous material regulations. Use proper containers, label clearly, and ensure compliance during transit to prevent any risks. |
Competitive Benzene, 1-(Bromomethyl)-2-Chloro-3-(Trifluoromethyl)- prices that fit your budget—flexible terms and customized quotes for every order.
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What are the chemical properties of this product 1- (bromomethyl) -2-chloro-3- (trifluoromethyl) benzene?
This substance is called 1- (hydroxymethyl) -2 -chloro-3- (trifluoromethyl) pyridine, and its chemical properties will be described in the style of ancient proverbs.
1- (hydroxymethyl) -2 -chloro-3- (trifluoromethyl) pyridine is active. In its molecular structure, hydroxymethyl (-CH ² OH) has some characteristics of alcohols. Hydroxyl groups can participate in many reactions, such as esterification with acids. Under specific conditions, concentrated sulfuric acid can be dehydrated to form alkenes or ethers. Due to the strong electronegativity of the oxygen atom, the hydroxyl hydrogen has a certain acidity. Although the acidity is weak, it can react in a strong alkali environment. The oxygen atom in the hydroxyl group also has lone pair electrons, which can be used as a nucleophilic reagent to participate in nucleophilic reactions.
Chlorine atom (-Cl) in this molecule has the properties of halogenated hydrocarbons due to its electronegativity and atomic radius. Nucleophilic substitution reactions can occur, such as with nucleophilic reagents such as sodium alcohol and ammonia, and the chlorine atom is replaced by the corresponding group. Under alkaline conditions, a hydrolysis reaction can occur, and the chlorine atom is replaced by a hydroxyl group to form an alcohol; when reacted with sodium cyanide, the chlorine atom is replaced by
Trifluoromethyl (-CF 🥰) has a strong electron-absorbing induction effect due to the strong electronegativity of fluorine atoms. It reduces the electron cloud density of the pyridine ring, weakens the electrophilic substitution activity on the pyridine ring, and enhances the chemical stability of the substance. Because of its fluorine content, the molecule has a certain lipid solubility and hydrophobicity, and has good solubility in some organic solvents. At the same time, trifluoromethyl affects the acidity of the molecule, enhancing the acidity of the ortho or para-hydrogen atom.
1- (hydroxymethyl) -2 -chloro-3- (trifluoromethyl) pyridine, due to the interaction of different functional groups, exhibits rich and diverse chemical properties. In the field of organic synthesis, it is often used as an important intermediate for the construction of complex organic compounds and participates in many organic reaction processes.
1- (hydroxymethyl) -2 -chloro-3- (trifluoromethyl) pyridine is active. In its molecular structure, hydroxymethyl (-CH ² OH) has some characteristics of alcohols. Hydroxyl groups can participate in many reactions, such as esterification with acids. Under specific conditions, concentrated sulfuric acid can be dehydrated to form alkenes or ethers. Due to the strong electronegativity of the oxygen atom, the hydroxyl hydrogen has a certain acidity. Although the acidity is weak, it can react in a strong alkali environment. The oxygen atom in the hydroxyl group also has lone pair electrons, which can be used as a nucleophilic reagent to participate in nucleophilic reactions.
Chlorine atom (-Cl) in this molecule has the properties of halogenated hydrocarbons due to its electronegativity and atomic radius. Nucleophilic substitution reactions can occur, such as with nucleophilic reagents such as sodium alcohol and ammonia, and the chlorine atom is replaced by the corresponding group. Under alkaline conditions, a hydrolysis reaction can occur, and the chlorine atom is replaced by a hydroxyl group to form an alcohol; when reacted with sodium cyanide, the chlorine atom is replaced by
Trifluoromethyl (-CF 🥰) has a strong electron-absorbing induction effect due to the strong electronegativity of fluorine atoms. It reduces the electron cloud density of the pyridine ring, weakens the electrophilic substitution activity on the pyridine ring, and enhances the chemical stability of the substance. Because of its fluorine content, the molecule has a certain lipid solubility and hydrophobicity, and has good solubility in some organic solvents. At the same time, trifluoromethyl affects the acidity of the molecule, enhancing the acidity of the ortho or para-hydrogen atom.
1- (hydroxymethyl) -2 -chloro-3- (trifluoromethyl) pyridine, due to the interaction of different functional groups, exhibits rich and diverse chemical properties. In the field of organic synthesis, it is often used as an important intermediate for the construction of complex organic compounds and participates in many organic reaction processes.
What are the main uses of 1- (bromomethyl) -2-chloro-3- (trifluoromethyl) benzene?
(Ether-based) -2-chloro-3- (trifluoromethyl) pyridine, this substance has a wide range of uses. In the field of medicine, it is often the key raw material for the creation of new specific drugs. Due to its special chemical structure, it can precisely combine with specific targets in organisms, exhibit excellent pharmacological activity, and has great potential for the treatment of many difficult diseases. For example, in the development of some anti-cancer drugs, this ingredient can effectively inhibit the proliferation of cancer cells, providing a new opportunity to overcome cancer problems.
In the field of pesticides, it is also indispensable. It can prepare high-efficiency and low-toxicity insecticides, which interfere with the nervous conduction system of pests and cause their physiological dysfunction to die. With its high selectivity, it has little harm to beneficial insects and the environment, and meets the needs of modern green agriculture development. It can ensure the harvest of crops while maintaining ecological balance.
In the field of materials science, it can be used as an intermediate for the synthesis of functional materials. After chemical modification and polymerization, the material is endowed with special properties, such as improving the stability, corrosion resistance and optical properties of polymer materials, and has broad application prospects in high-end fields such as electronic devices and aerospace materials.
To sum up, (ether-based) -2-chloro-3- (trifluoromethyl) pyridine plays a key role in many fields such as medicine, pesticides and materials science, and promotes technological innovation and development in various fields.
In the field of pesticides, it is also indispensable. It can prepare high-efficiency and low-toxicity insecticides, which interfere with the nervous conduction system of pests and cause their physiological dysfunction to die. With its high selectivity, it has little harm to beneficial insects and the environment, and meets the needs of modern green agriculture development. It can ensure the harvest of crops while maintaining ecological balance.
In the field of materials science, it can be used as an intermediate for the synthesis of functional materials. After chemical modification and polymerization, the material is endowed with special properties, such as improving the stability, corrosion resistance and optical properties of polymer materials, and has broad application prospects in high-end fields such as electronic devices and aerospace materials.
To sum up, (ether-based) -2-chloro-3- (trifluoromethyl) pyridine plays a key role in many fields such as medicine, pesticides and materials science, and promotes technological innovation and development in various fields.
What is the preparation method of 1- (bromomethyl) -2-chloro-3- (trifluoromethyl) benzene?
To make 1 - (hydroxymethyl) - 2 - chloro - 3 - (trifluoromethyl) pyridine, you can follow the following ancient method.
Take the appropriate raw materials first, among which the pyridine parent should be selected with good texture and few impurities. In a clean kettle, add pyridine, preferably in a low temperature environment, and slowly drop in the chlorine-containing reagent. This process requires careful temperature control to make the reaction proceed mildly. Because the temperature is too high, it is easy to cause side reactions and affect the purity of the product. The dripping acceleration of the chlorine reagent also needs to be accurately grasped. If it is too fast, the reaction will be violent and difficult to control, and if it is too slow, it will take a long time.
After the chlorine substitution reaction is generally completed, after careful testing confirms that the 2-position of pyridine has been successfully introduced into the chlorine atom, the hydroxymethyl group is introduced instead. Select a suitable hydroxymethylation reagent and add it to the system under the action of a specific catalyst. The amount of catalyst needs to be precisely prepared, and more catalysis is excessive, and less reaction is slow. During the reaction, it is necessary to stir in a timely manner to make the reactants fully contact and improve the reaction efficiency.
As for the introduction of trifluoromethyl, this step is quite critical. Select a high-efficiency trifluoromethylation reagent and add it under suitable reaction conditions. It may be necessary to adjust the pH, temperature and other factors of the reaction to promote the smooth connection of trifluoromethyl to the 3-position of py In this process, it is necessary to use a variety of detection methods, such as chromatographic analysis, to monitor the reaction process in real time to ensure that each step of the reaction is carried out as expected.
After each step of the reaction is completed, it needs to go through the process of separation and purification. Or use distillation to separate the target product and impurities according to the difference in the boiling point of each substance; or use extraction to take advantage of the different solubility of the product and impurities in different solvents to achieve the purpose of purification. After multiple operations and careful control, high-purity 1- (hydroxymethyl) -2-chloro-3- (trifluoromethyl) pyridine can be prepared.
Take the appropriate raw materials first, among which the pyridine parent should be selected with good texture and few impurities. In a clean kettle, add pyridine, preferably in a low temperature environment, and slowly drop in the chlorine-containing reagent. This process requires careful temperature control to make the reaction proceed mildly. Because the temperature is too high, it is easy to cause side reactions and affect the purity of the product. The dripping acceleration of the chlorine reagent also needs to be accurately grasped. If it is too fast, the reaction will be violent and difficult to control, and if it is too slow, it will take a long time.
After the chlorine substitution reaction is generally completed, after careful testing confirms that the 2-position of pyridine has been successfully introduced into the chlorine atom, the hydroxymethyl group is introduced instead. Select a suitable hydroxymethylation reagent and add it to the system under the action of a specific catalyst. The amount of catalyst needs to be precisely prepared, and more catalysis is excessive, and less reaction is slow. During the reaction, it is necessary to stir in a timely manner to make the reactants fully contact and improve the reaction efficiency.
As for the introduction of trifluoromethyl, this step is quite critical. Select a high-efficiency trifluoromethylation reagent and add it under suitable reaction conditions. It may be necessary to adjust the pH, temperature and other factors of the reaction to promote the smooth connection of trifluoromethyl to the 3-position of py In this process, it is necessary to use a variety of detection methods, such as chromatographic analysis, to monitor the reaction process in real time to ensure that each step of the reaction is carried out as expected.
After each step of the reaction is completed, it needs to go through the process of separation and purification. Or use distillation to separate the target product and impurities according to the difference in the boiling point of each substance; or use extraction to take advantage of the different solubility of the product and impurities in different solvents to achieve the purpose of purification. After multiple operations and careful control, high-purity 1- (hydroxymethyl) -2-chloro-3- (trifluoromethyl) pyridine can be prepared.
What are the precautions for storing and transporting 1- (bromomethyl) -2-chloro-3- (trifluoromethyl) benzene?
Mercury, (benzyl), (trichlorovinyl) ether, when storing and transporting, need to pay attention to many matters.
Mercury is liquid at room temperature, volatile, and its vapor is highly toxic. When storing, be sure to choose a cool, well-ventilated place and seal it tightly to prevent mercury volatilization from escaping. The container should also be solid and airtight to avoid leakage. During handling, care should be taken to prevent damage to the container due to vibration and collision. Once mercury is spilled, it should be quickly covered with sulfur powder to form mercury sulfide, reduce toxicity, and properly collected and cleaned.
(benzyl) materials are more flammable. Storage should be kept away from fire and heat sources and placed in a cool and dry place. The warehouse must be equipped with complete fire protection facilities, such as fire extinguishers, fire sand, etc. During transportation, the vehicles used should be equipped with fire protection and anti-static devices, and drive according to the specified route, avoiding crowded places and high temperature areas.
(trichlorovinyl) ethers, some of which are toxic and irritating. The storage environment should be kept dry to prevent moisture and deterioration. Packaging must be tight to prevent leakage from causing harm to the surrounding environment and human body. During transportation, pay close attention to temperature and pressure changes. If it is transported in cans, regularly check the tank for signs of leakage. When handling such items, operators should wear protective clothing, protective gloves and masks, and take personal protective measures to ensure safety.
Mercury is liquid at room temperature, volatile, and its vapor is highly toxic. When storing, be sure to choose a cool, well-ventilated place and seal it tightly to prevent mercury volatilization from escaping. The container should also be solid and airtight to avoid leakage. During handling, care should be taken to prevent damage to the container due to vibration and collision. Once mercury is spilled, it should be quickly covered with sulfur powder to form mercury sulfide, reduce toxicity, and properly collected and cleaned.
(benzyl) materials are more flammable. Storage should be kept away from fire and heat sources and placed in a cool and dry place. The warehouse must be equipped with complete fire protection facilities, such as fire extinguishers, fire sand, etc. During transportation, the vehicles used should be equipped with fire protection and anti-static devices, and drive according to the specified route, avoiding crowded places and high temperature areas.
(trichlorovinyl) ethers, some of which are toxic and irritating. The storage environment should be kept dry to prevent moisture and deterioration. Packaging must be tight to prevent leakage from causing harm to the surrounding environment and human body. During transportation, pay close attention to temperature and pressure changes. If it is transported in cans, regularly check the tank for signs of leakage. When handling such items, operators should wear protective clothing, protective gloves and masks, and take personal protective measures to ensure safety.
What are the market prospects for 1- (bromomethyl) -2-chloro-3- (trifluoromethyl) benzene?
In today's world, the prospects of (cyanomethyl), tritium, and (trifluoromethyl) ethers in the market are related to the rise and fall of many industries, and cannot be ignored.
(cyanomethyl) is active in nature and is often a key intermediate in the field of organic synthesis. In the pharmaceutical and chemical industry, the preparation of many special drugs depends on its participation in the reaction to form a complex molecular structure and seek well-being for human health. Looking at the current booming pharmaceutical market, new diseases are waiting to be treated, and new drug R & D requests are on the rise. (cyanomethyl) can help the synthesis of various drugs, so its prospects are quite promising. And in materials science, the creation of some high-performance polymers also requires (cyanomethyl) assistance to give materials special properties, such as better heat resistance and corrosion resistance. With the advancement of science and technology, the demand for materials is moving towards high-end, and the demand for (cyanomethyl) in this direction will also increase.
Although tritium is radioactive, it has its unique uses in scientific research and energy fields. In scientific research, it is often used as a tracer to help scientists understand the mechanism of chemical reactions and the metabolic pathways of substances in living organisms, providing key clues for in-depth research in many disciplines. In terms of energy, tritium is an important fuel for nuclear fusion. Nuclear fusion energy is clean and efficient. If the technology is mature, it will find a solution to the global energy dilemma. Nowadays, the development of clean energy is all over the world, and nuclear fusion research continues to advance. The importance of tritium is becoming more and more prominent, and its market prospect is also becoming broader with the change of energy pattern.
(trifluoromethyl) ether has excellent thermal stability, chemical stability and low surface energy due to the characteristics of fluorine atoms. In the field of pesticides, pesticides containing (trifluoromethyl) ether structure have the characteristics of high efficiency, low toxicity and wide range, which can effectively control pests and diseases, ensure agricultural harvest, and meet the needs of the current green agriculture development. In electronic materials, such as photoresists, etc., (trifluoromethyl) ether can optimize the performance of materials to meet the trend of miniaturization and high performance of electronic equipment. With the continuous upgrading of the agricultural and electronic industries, the demand for (trifluoromethyl) ether in the market is expected to rise steadily.
In summary, (cyanomethyl), tritium, and (trifluoromethyl) ether, in various self-related fields, are driven by the development of the industry, and have considerable prospects, and may occupy an increasingly important position in the market in the future.
(cyanomethyl) is active in nature and is often a key intermediate in the field of organic synthesis. In the pharmaceutical and chemical industry, the preparation of many special drugs depends on its participation in the reaction to form a complex molecular structure and seek well-being for human health. Looking at the current booming pharmaceutical market, new diseases are waiting to be treated, and new drug R & D requests are on the rise. (cyanomethyl) can help the synthesis of various drugs, so its prospects are quite promising. And in materials science, the creation of some high-performance polymers also requires (cyanomethyl) assistance to give materials special properties, such as better heat resistance and corrosion resistance. With the advancement of science and technology, the demand for materials is moving towards high-end, and the demand for (cyanomethyl) in this direction will also increase.
Although tritium is radioactive, it has its unique uses in scientific research and energy fields. In scientific research, it is often used as a tracer to help scientists understand the mechanism of chemical reactions and the metabolic pathways of substances in living organisms, providing key clues for in-depth research in many disciplines. In terms of energy, tritium is an important fuel for nuclear fusion. Nuclear fusion energy is clean and efficient. If the technology is mature, it will find a solution to the global energy dilemma. Nowadays, the development of clean energy is all over the world, and nuclear fusion research continues to advance. The importance of tritium is becoming more and more prominent, and its market prospect is also becoming broader with the change of energy pattern.
(trifluoromethyl) ether has excellent thermal stability, chemical stability and low surface energy due to the characteristics of fluorine atoms. In the field of pesticides, pesticides containing (trifluoromethyl) ether structure have the characteristics of high efficiency, low toxicity and wide range, which can effectively control pests and diseases, ensure agricultural harvest, and meet the needs of the current green agriculture development. In electronic materials, such as photoresists, etc., (trifluoromethyl) ether can optimize the performance of materials to meet the trend of miniaturization and high performance of electronic equipment. With the continuous upgrading of the agricultural and electronic industries, the demand for (trifluoromethyl) ether in the market is expected to rise steadily.
In summary, (cyanomethyl), tritium, and (trifluoromethyl) ether, in various self-related fields, are driven by the development of the industry, and have considerable prospects, and may occupy an increasingly important position in the market in the future.
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