Benzene, 1-Chloro-4-(2-Chloroethyl)-
Linshang Chemical
HS Code |
985963 |
Chemical Formula | C8H8Cl2 |
Molar Mass | 175.055 g/mol |
Appearance | Colorless to light - yellow liquid |
Odor | Aromatic odor |
Density | 1.247 g/cm³ (at 20°C) |
Boiling Point | 236 - 238°C |
Melting Point | -43°C |
Solubility In Water | Insoluble |
Solubility In Organic Solvents | Soluble in most organic solvents like ethanol, ether |
Vapor Pressure | Low vapor pressure at room temperature |
Flash Point | 99°C |
Hazard Class | Toxic, possible carcinogen |
As an accredited Benzene, 1-Chloro-4-(2-Chloroethyl)- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 1 - chloro - 4 - (2 - chloroethyl) benzene: Packed in 500 - gram bottles for chemical use. |
Storage | Store “Benzene, 1 - chloro - 4 - (2 - chloroethyl)-” in a cool, well - ventilated area away from heat, sparks, and open flames. Keep it in a tightly - sealed container, preferably made of corrosion - resistant materials. Separate from oxidizing agents, acids, and bases. Store in accordance with local regulations to prevent environmental contamination and ensure safety. |
Shipping | Benzene, 1 - chloro - 4 - (2 - chloroethyl)- is a hazardous chemical. Shipping must follow strict regulations, using appropriate containers to prevent leakage, and with proper labeling for safety during transportation. |
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As a leading Benzene, 1-Chloro-4-(2-Chloroethyl)- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
First of all, its molecular structure contains benzene ring, chlorine atom and chloroethyl group. The benzene ring is a stable structure, but the substitution of chlorine atom and chloroethyl group makes the molecule have unique chemical activity. Its chlorine atom can undergo nucleophilic substitution reaction. In case of nucleophilic reagents, nucleophilic reagents can attack the carbon atom attached to chlorine, and the chlorine atom leaves in the form of chloride ion, thereby forming a new compound.
Furthermore, the chloroethyl part of the substance also has certain reactivity. The chlorine atom in chloroethyl is active and can participate in many reactions. For example, elimination reactions can occur under alkaline conditions, removing hydrogen chloride, forming carbon-carbon double bonds, and forming compounds with unsaturated bonds.
In addition, 1-chloro-4 - (2-chloroethyl) phenyl contains benzene rings, and typical reactions of benzene rings can occur, such as electrophilic substitution reactions. The electron cloud density on the benzene ring is high, and it is vulnerable to attack by electrophilic reagents. Reactions such as halogenation, nitrification, and sulfonation occur. And because the chlorine atom is an ortho-para localization group, the reaction mainly occurs in the ortho-position and para-position of the chlorine atom in the benzene ring.
At the same time, the compound may undergo reactions such as the removal of chlorine atoms at high temperature or in the presence of specific catalysts, thereby changing the molecular structure and properties.
In summary, the unique molecular structure of 1-chloro-4- (2-chloroethyl) benzene has a variety of chemical properties such as nucleophilic substitution, elimination, and electrophilic substitution, and has important applications in organic synthesis and other fields.
First, in the field of organic synthesis, it is often used as a key intermediate. With the activity of chlorine atoms in its structure, it can interact with many nucleophilic reagents, such as alcohols, amines, and thiols, by means of nucleophilic substitution reactions. For example, when reacted with alcohols under basic conditions, corresponding ether compounds can be formed; when reacted with amines, amine substitution products can be prepared. These products are of great significance in many fields such as pharmaceutical chemistry and materials science.
Second, in the field of drug research and development, the structure of this compound can be modified and optimized, or it can exhibit specific biological activities. Or it can be used as a lead compound to provide a basis for the creation of new drugs. The presence of its benzene ring and chlorine atomic substituents affects the interaction mode between drug molecules and target proteins, or can enhance the affinity of drugs and targets, thereby enhancing drug efficacy.
Third, in the field of materials science, 1-chloro-4- (2-chloroethyl) benzene can be used to prepare functional polymer materials. By polymerizing with other monomers, specific functional groups are introduced into the polymer chain, giving the material unique properties, such as improving the solubility, thermal stability or optical properties of the material. Fourth, it is also used in the preparation of fine chemical products. For example, it can be used to synthesize fine chemicals such as surfactants, fragrances, and pesticides with special structures. Due to the particularity of its structure, it may endow fine chemical products with unique performance and quality.
Benzene can be reacted with 1,2-dichloroethane under the action of an appropriate catalyst. First take an appropriate amount of benzene and place it in the reaction kettle. The benzene needs to be purified to remove impurities and maintain its purity. Then add 1,2-dichloroethane slowly into the kettle. The ratio of the two should be precisely prepared, depending on the stoichiometric relationship of the reaction and the actual situation.
In this process, a catalyst needs to be introduced. Commonly used catalysts, such as aluminum trichloride, have high activity and can effectively promote the reaction. When adding an appropriate amount of aluminum trichloride, it can be dispersed in the system in a specific way to ensure its uniform distribution and give full play to the catalytic effect.
During the reaction, the temperature is strictly controlled. This reaction is mostly exothermic, and if the temperature is too high, it is easy to cause side reactions to occur, which affects the purity and yield of the product. Generally speaking, the reaction temperature is controlled within a certain suitable range, such as between tens of degrees Celsius, and the temperature is stabilized by cooling or heating devices.
At the same time, attention should also be paid to the pressure of the reaction system. Keeping the pressure of the system stable can make the reaction proceed smoothly. If the pressure is too high or too low, it may have an adverse effect on the reaction rate and the formation of the product.
After the reaction reaches a certain time, the reaction tends to be completed. At this time, the reaction products are separated and purified. Distillation can be used first to take advantage of the difference in the boiling points of each substance to initially separate the fractions containing the target product. After that, extraction, recrystallization and other means are further purified to obtain purified 1-chloro-4- (2-chloroethyl) benzene. In this way, the desired 1-chloro-4- (2-chloroethyl) benzene can be prepared.
Looking at its chemical composition, it contains chlorine atoms, which is one of the key factors affecting the environment. The activity of chlorine atoms is quite high, and this compound may undergo a series of complex reactions in the natural environment. In soil, it may interact with soil particles, causing its own migration and bioavailability. Due to its hydrophobicity, or adsorption to soil organic matter, it is difficult to dissolve in water, causing it to remain in the soil for a long time and accumulate gradually, which in turn has adverse effects on many links of the soil ecosystem, such as soil microbial activity and soil enzyme activity. Soil microorganisms are crucial in soil material cycle and nutrient transformation. The accumulation of this compound may inhibit the growth and metabolism of microorganisms and disrupt the soil ecological balance.
As for the water environment, although the solubility of 1-chloro-4- (2-chloroethyl) benzene is limited, it will also cause harm once it enters the water body. It may pose a direct threat to aquatic organisms, because aquatic organisms are easily exposed to and absorbed this compound during ingestion and respiration. Studies have shown that many chlorine-containing organic compounds have toxic effects on aquatic organisms, or affect their growth, development and reproduction. If it can interfere with the endocrine system of aquatic organisms, cause reproductive abnormalities; it can also damage their nervous system, affect their behavior, and even cause death in severe cases. And in water, this compound may generate other more toxic intermediate products through photolysis, hydrolysis and other reactions, further exacerbating water pollution.
In the atmospheric environment, 1-chloro-4- (2-chloroethyl) benzene may enter the atmosphere through volatilization. In the atmosphere, it can participate in photochemical reactions and interact with active substances such as free radicals. Such reactions may generate secondary pollutants, such as ozone, organic aerosols, etc., which have a negative impact on air quality, aggravate air pollution phenomena such as smog, and threaten human health and the ecological environment.
In summary, the chemical properties of 1-chloro-4- (2-chloroethyl) benzene itself can cause a series of environmental problems in various environmental media such as soil, water, and atmosphere. It should be highly valued, studied in depth, and properly prevented and controlled.
It is toxic to a certain extent. When storing, choose a cool and ventilated warehouse, away from fire and heat sources. The storage temperature should not exceed 30 ° C. It should be stored separately from oxidants and food chemicals, and should not be mixed. The storage area should be equipped with emergency treatment equipment for leakage and suitable containment materials. If this substance is not properly managed, leaks into the environment, or causes pollution, it is also harmful to human and animal health.
When transporting, make sure that the container does not leak, collapse, fall, or damage. During transportation, it should be protected from exposure to the sun, rain and high temperature. The tank (tank) car used during transportation should have a grounding chain, and holes can be set in the tank to baffle to reduce shock and generate static electricity. It is strictly forbidden to mix and transport with oxidants, edible chemicals, etc. During transportation, it should be driven according to the specified route, and do not stop in residential areas and densely populated areas.
When loading and unloading, operators must wear suitable protective equipment, pack and unload lightly, and prevent damage to packaging and containers.
All of these are related to the safety of 1-chloro-4- (2-chloroethyl) benzene storage and transportation. If there is a slight risk of dredging or causing a disaster, it must be treated with caution.

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