Linshang Chemical
PRODUCTS
Benzene, 1-Chloro-4-Fluoro-2-Methoxy-
Linshang Chemical
|
HS Code |
587708 |
| Chemical Formula | C7H6ClFO |
| Molecular Weight | 160.57 |
As an accredited Benzene, 1-Chloro-4-Fluoro-2-Methoxy- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 1 - chloro - 4 - fluoro - 2 - methoxy - benzene in sealed chemical - grade bottles. |
| Storage | Store "Benzene, 1 - chloro - 4 - fluoro - 2 - methoxy -" in a cool, well - ventilated area away from heat, sparks, and open flames. Keep it in a tightly closed container, preferably made of corrosion - resistant materials. Isolate it from oxidizing agents, reducing agents, and reactive chemicals to prevent hazardous reactions. |
| Shipping | The chemical "Benzene, 1 - chloro - 4 - fluoro - 2 - methoxy -" should be shipped in well - sealed, corrosion - resistant containers. Label containers clearly. Follow strict regulations for hazardous chemicals during shipping to ensure safety. |
Competitive Benzene, 1-Chloro-4-Fluoro-2-Methoxy- prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy Benzene, 1-Chloro-4-Fluoro-2-Methoxy- in China?
As a trusted Benzene, 1-Chloro-4-Fluoro-2-Methoxy- manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading Benzene, 1-Chloro-4-Fluoro-2-Methoxy- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the chemical properties of 1-chloro-4-fluoro-2-methoxybenzene?
"Tiangong Kaiwu" said: "1 + - + alkane-4-ene-2-methoxybenzene, this is an organic compound. Its chemical properties are quite rich, let me tell you in detail.
In this compound, the presence of alkenyl and methoxy groups gives it unique reactivity. Alkenyl groups are unsaturated and prone to addition reactions. For example, they can be added to halogen elementals such as bromine (Br ²) to form halogens. In this process, the carbon-carbon double bond breaks, and bromine atoms are added to the carbon atoms at both ends of the double bond. This is a typical electrophilic addition reaction, which is caused by the high electron cloud density of alkenyl groups. The electron cloud density of the benzene ring can be increased by methoxy group (-OCH), which can affect the electrophilic substitution activity of the benzene ring. When encountering electrophilic reagents, such as nitro positive ions (NO ²), the adjacent and para-sites of the methoxy group are more prone to substitution reactions. Because the methoxy group increases the electron cloud density of the adjacent and para-sites through the conjugation effect, the electrophilic reagents are more likely to attack these two positions.
In addition, due to the difference in electronegativity of different atoms in the molecule of the compound, the molecule has a certain polarity, which also affects its physical properties, such as solubility and boiling point. In organic solvents, its solubility is relatively good. Due to the principle of similar miscibility, organic solvents are similar to the polarity of the compound. The boiling point is affected by the intermolecular force, and the existence of polarity enhances the intermolecular force, and the boiling point also increases accordingly.
Furthermore, under appropriate conditions, the carbon atoms connected to the methoxy group in this compound may undergo a nucleophilic substitution reaction, and the methoxy group can be replaced by other nucleophilic reagents. This reaction requires suitable reaction conditions and nucleophilic reagents to proceed smoothly. "
In this compound, the presence of alkenyl and methoxy groups gives it unique reactivity. Alkenyl groups are unsaturated and prone to addition reactions. For example, they can be added to halogen elementals such as bromine (Br ²) to form halogens. In this process, the carbon-carbon double bond breaks, and bromine atoms are added to the carbon atoms at both ends of the double bond. This is a typical electrophilic addition reaction, which is caused by the high electron cloud density of alkenyl groups. The electron cloud density of the benzene ring can be increased by methoxy group (-OCH), which can affect the electrophilic substitution activity of the benzene ring. When encountering electrophilic reagents, such as nitro positive ions (NO ²), the adjacent and para-sites of the methoxy group are more prone to substitution reactions. Because the methoxy group increases the electron cloud density of the adjacent and para-sites through the conjugation effect, the electrophilic reagents are more likely to attack these two positions.
In addition, due to the difference in electronegativity of different atoms in the molecule of the compound, the molecule has a certain polarity, which also affects its physical properties, such as solubility and boiling point. In organic solvents, its solubility is relatively good. Due to the principle of similar miscibility, organic solvents are similar to the polarity of the compound. The boiling point is affected by the intermolecular force, and the existence of polarity enhances the intermolecular force, and the boiling point also increases accordingly.
Furthermore, under appropriate conditions, the carbon atoms connected to the methoxy group in this compound may undergo a nucleophilic substitution reaction, and the methoxy group can be replaced by other nucleophilic reagents. This reaction requires suitable reaction conditions and nucleophilic reagents to proceed smoothly. "
What are the physical properties of 1-chloro-4-fluoro-2-methoxybenzene
The physical rationality of 1 + -alkane-4-ene-2-methoxybenzene is as follows:
This compound is often liquid under normal conditions, due to its molecular force. It has a certain degree of stability. Due to the limitation of the amount of molecular phase and the attractive force of the molecule, the degree of stability is limited to the small molecule.
Its density is water. If water is co-located, it often floats on the water surface. This is due to the determination of the atom, mesh and arrangement of the molecules, resulting in a small amount of water.
In terms of solubility, it has the best solubility in non-soluble compounds such as benzene and carbon tetrachloride. According to the principle of "similar phase dissolution", the compounds have certain non-soluble properties, and the non-soluble compounds are easy to interact. In water and other soluble compounds with low solubility, the solubility is very small, and the molecules can interact effectively due to the large difference in solubility.
The melting boiling is affected by molecular forces, including van der force, etc. The phase is small molecule alkane, because its molecule is slightly larger and contains methoxy groups, the molecular force is increased, and the melting boiling is also higher. But it is lower than some compounds with special effects such as methoxy.
The refractive index also depends on its important physical properties, reflecting the transformation of light in its propagation rate, molecular properties, and sub-cloud distribution. The specific refractive index can be used as one of the factors for determining this compound. In addition, the multi-physical properties are mutually dependent and determined by their molecules.
This compound is often liquid under normal conditions, due to its molecular force. It has a certain degree of stability. Due to the limitation of the amount of molecular phase and the attractive force of the molecule, the degree of stability is limited to the small molecule.
Its density is water. If water is co-located, it often floats on the water surface. This is due to the determination of the atom, mesh and arrangement of the molecules, resulting in a small amount of water.
In terms of solubility, it has the best solubility in non-soluble compounds such as benzene and carbon tetrachloride. According to the principle of "similar phase dissolution", the compounds have certain non-soluble properties, and the non-soluble compounds are easy to interact. In water and other soluble compounds with low solubility, the solubility is very small, and the molecules can interact effectively due to the large difference in solubility.
The melting boiling is affected by molecular forces, including van der force, etc. The phase is small molecule alkane, because its molecule is slightly larger and contains methoxy groups, the molecular force is increased, and the melting boiling is also higher. But it is lower than some compounds with special effects such as methoxy.
The refractive index also depends on its important physical properties, reflecting the transformation of light in its propagation rate, molecular properties, and sub-cloud distribution. The specific refractive index can be used as one of the factors for determining this compound. In addition, the multi-physical properties are mutually dependent and determined by their molecules.
What are the common uses of 1-chloro-4-fluoro-2-methoxybenzene?
The common use of 3-hydroxy- 4-ethyl-2-methoxybenzene is also in the field of medicine and chemical industry.
In the way of medicine, it is an intermediate of the drug. It covers the synthesis of many drugs and relies on this as the basis. For example, when some drugs for treating diseases of the nervous system are synthesized, 3-hydroxy- 4-ethyl-2-methoxybenzene can be reacted and transformed into a therapeutic drug. Because of its unique structure, it can play a specific role with molecules in the body of organisms and help drugs achieve the effect of treating diseases.
In the way of chemical industry, it is also very useful. It can be used as a raw material for the synthesis of fragrances. Because of its own unique chemical structure, it can be prepared by chemical technology to impart a different flavor to fragrances. When making high-end perfumes or daily fragrances, adding this substance can make the aroma rich in layers, unique and charming, and enhance the charm and value of the fragrance.
can also be used in the manufacture of dyes. Its structure can make the dye have excellent dyeing properties. When it is applied to fabrics, the color is bright and long-lasting, and it is washable and sun-resistant. In the textile printing and dyeing industry, the dyes obtained from this can dye all kinds of brilliant colors to meet the needs of the world for the beauty of fab
Furthermore, in the emerging field of materials science, 3-hydroxy- 4-ethyl-2-methoxybenzene has also emerged. Or involved in the research and development of new functional materials, with its special chemical properties, it adds specific properties to materials, such as conductivity, optics and other properties, and opens up new fields of material application.
In summary, 3-hydroxy- 4-ethyl-2-methoxybenzene occupies an important position in many industries such as medicine and chemical industry, and is also an important substance to promote the development of various industries.
In the way of medicine, it is an intermediate of the drug. It covers the synthesis of many drugs and relies on this as the basis. For example, when some drugs for treating diseases of the nervous system are synthesized, 3-hydroxy- 4-ethyl-2-methoxybenzene can be reacted and transformed into a therapeutic drug. Because of its unique structure, it can play a specific role with molecules in the body of organisms and help drugs achieve the effect of treating diseases.
In the way of chemical industry, it is also very useful. It can be used as a raw material for the synthesis of fragrances. Because of its own unique chemical structure, it can be prepared by chemical technology to impart a different flavor to fragrances. When making high-end perfumes or daily fragrances, adding this substance can make the aroma rich in layers, unique and charming, and enhance the charm and value of the fragrance.
can also be used in the manufacture of dyes. Its structure can make the dye have excellent dyeing properties. When it is applied to fabrics, the color is bright and long-lasting, and it is washable and sun-resistant. In the textile printing and dyeing industry, the dyes obtained from this can dye all kinds of brilliant colors to meet the needs of the world for the beauty of fab
Furthermore, in the emerging field of materials science, 3-hydroxy- 4-ethyl-2-methoxybenzene has also emerged. Or involved in the research and development of new functional materials, with its special chemical properties, it adds specific properties to materials, such as conductivity, optics and other properties, and opens up new fields of material application.
In summary, 3-hydroxy- 4-ethyl-2-methoxybenzene occupies an important position in many industries such as medicine and chemical industry, and is also an important substance to promote the development of various industries.
What are the synthesis methods of 1-chloro-4-fluoro-2-methoxybenzene?
To prepare 1-bromo-4-pentene-2-methoxyphenyl, there are three methods.
First, start with 4-pentene-2-alcohol, first heat with methanol and sulfuric acid to obtain 4-pentene-2-methyl ether. After that, liquid bromine is slowly added dropwise to a low temperature, inert solvent such as dichloromethane to obtain the target. This process requires temperature control, because olefins are prone to excessive addition with bromine, and if the temperature is too high, there will be many side reactions.
Second, take 2-methoxy benzene first, use N-bromosuccinimide (NBS) and an initiator such as benzoyl peroxide, and undergo free radical substitution in an inert solvent, heating or lighting conditions to obtain 2-methoxy-1-bromobenzene. Then it is prepared by nucleophilic substitution reaction with 4-pentene-2-ol under alkaline conditions and catalyst action. It should be noted that excessive alkalinity or improper catalyst dosage will cause side reactions and affect the yield.
Third, use 2-methoxybenzene as raw material to make Grignard reagent first and react with 4-pentene-2-bromine. The preparation of Grignard reagent requires an anhydrous environment, otherwise it is easy to react with water and fail. After the reaction is completed, the product can be obtained by hydrolysis after acid treatment. During operation, the acid concentration and treatment time need to be accurately controlled, otherwise it will affect the purity and yield of the product.
These three methods have their own advantages and disadvantages. In actual synthesis, the best method should be selected according to the comprehensive consideration of raw material availability, cost, equipment conditions and product purity requirements.
First, start with 4-pentene-2-alcohol, first heat with methanol and sulfuric acid to obtain 4-pentene-2-methyl ether. After that, liquid bromine is slowly added dropwise to a low temperature, inert solvent such as dichloromethane to obtain the target. This process requires temperature control, because olefins are prone to excessive addition with bromine, and if the temperature is too high, there will be many side reactions.
Second, take 2-methoxy benzene first, use N-bromosuccinimide (NBS) and an initiator such as benzoyl peroxide, and undergo free radical substitution in an inert solvent, heating or lighting conditions to obtain 2-methoxy-1-bromobenzene. Then it is prepared by nucleophilic substitution reaction with 4-pentene-2-ol under alkaline conditions and catalyst action. It should be noted that excessive alkalinity or improper catalyst dosage will cause side reactions and affect the yield.
Third, use 2-methoxybenzene as raw material to make Grignard reagent first and react with 4-pentene-2-bromine. The preparation of Grignard reagent requires an anhydrous environment, otherwise it is easy to react with water and fail. After the reaction is completed, the product can be obtained by hydrolysis after acid treatment. During operation, the acid concentration and treatment time need to be accurately controlled, otherwise it will affect the purity and yield of the product.
These three methods have their own advantages and disadvantages. In actual synthesis, the best method should be selected according to the comprehensive consideration of raw material availability, cost, equipment conditions and product purity requirements.
What are the environmental effects of 1-chloro-4-fluoro-2-methoxybenzene?
1-Chloro-4-bromo-2-methoxyphenyl benzene is one of the compounds, and its molecules contain chlorine, bromine and methoxy groups. This substance is occasionally useful in the fields of synthesis, chemical research, etc., but the impact of its environment cannot be ignored.
1. The shadow of the water environment
If 1-chloro-4-bromo-2-methoxybenzene enters the water, because of its hydrophobicity, it dissolves in water, or it is adsorbed on the floating matter and settles to the bottom. During this process, it may cause direct poisoning to aquatic organisms. For example, the chlorine atoms (chlorine and bromine) it contains may be able to affect the physiological generation of aquatic organisms. The physiological system of photosynthesis and respiration of aquatic plants, or due to exposure to this substance, causes their growth to be blocked, which affects the energy flow of aquatic systems. In terms of aquatic organisms, it may break the integrity of their cellular membranes, dry up and make them difficult to survive.
Second, the impact of soil environment
If this substance enters the soil, its chemical properties are determined, and it is not easy to be rapidly decomposed by soil microorganisms, or it may accumulate in the soil. As a result, it may affect the soil's chemical properties, such as soil acidity, porosity, etc. The function of soil microbial communities is also affected by it. Some soil fertility is improved to the level of important microorganisms, such as nitrogen-fixing bacteria, phosphorus-solubilizing bacteria, etc., and their activity may be inhibited, resulting in a decrease in soil fertility, which affects the growth of plants. And the plant root system absorbs water, or absorbs it into this material, which can affect higher-quality organisms from food.
Third, in the shadow of the environment,
1-chloro-4-bromo-2-methoxybenzene is not easy to transfer, but under specific conditions, such as high temperature, low light, etc., a small amount may enter the atmosphere. This substance enters the atmosphere, and may cause disruption and generate new harmful substances. For example, other free radicals in the atmosphere can generate reactions, generate secondary pollutants, affect the energy level, and increase the formation of photochemical emissions, which can cause irritation to the respiratory system, eyes, etc., and endanger human health.
Therefore, 1-chloro-4-bromo-2-methoxybenzene may cause many adverse effects in water, soil, and other environments. Therefore, it is necessary to be careful with its use and discharge to ensure the safety of the environment.
1. The shadow of the water environment
If 1-chloro-4-bromo-2-methoxybenzene enters the water, because of its hydrophobicity, it dissolves in water, or it is adsorbed on the floating matter and settles to the bottom. During this process, it may cause direct poisoning to aquatic organisms. For example, the chlorine atoms (chlorine and bromine) it contains may be able to affect the physiological generation of aquatic organisms. The physiological system of photosynthesis and respiration of aquatic plants, or due to exposure to this substance, causes their growth to be blocked, which affects the energy flow of aquatic systems. In terms of aquatic organisms, it may break the integrity of their cellular membranes, dry up and make them difficult to survive.
Second, the impact of soil environment
If this substance enters the soil, its chemical properties are determined, and it is not easy to be rapidly decomposed by soil microorganisms, or it may accumulate in the soil. As a result, it may affect the soil's chemical properties, such as soil acidity, porosity, etc. The function of soil microbial communities is also affected by it. Some soil fertility is improved to the level of important microorganisms, such as nitrogen-fixing bacteria, phosphorus-solubilizing bacteria, etc., and their activity may be inhibited, resulting in a decrease in soil fertility, which affects the growth of plants. And the plant root system absorbs water, or absorbs it into this material, which can affect higher-quality organisms from food.
Third, in the shadow of the environment,
1-chloro-4-bromo-2-methoxybenzene is not easy to transfer, but under specific conditions, such as high temperature, low light, etc., a small amount may enter the atmosphere. This substance enters the atmosphere, and may cause disruption and generate new harmful substances. For example, other free radicals in the atmosphere can generate reactions, generate secondary pollutants, affect the energy level, and increase the formation of photochemical emissions, which can cause irritation to the respiratory system, eyes, etc., and endanger human health.
Therefore, 1-chloro-4-bromo-2-methoxybenzene may cause many adverse effects in water, soil, and other environments. Therefore, it is necessary to be careful with its use and discharge to ensure the safety of the environment.
Scan to WhatsApp
