Linshang Chemical
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Benzene,1-Chloro-4-(Methoxymethoxy)-2-Methyl-
Linshang Chemical
|
HS Code |
175912 |
| Chemical Formula | C9H11ClO2 |
| Molar Mass | 186.64 g/mol |
As an accredited Benzene,1-Chloro-4-(Methoxymethoxy)-2-Methyl- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 - chloro - 4 - (methoxymethoxy)-2 - methyl - benzene in 500 - gram sealed chemical - grade containers. |
| Storage | Store “Benzene, 1 - chloro - 4 - (methoxymethoxy)-2 - methyl -” in a cool, well - ventilated area, away from heat, sparks, and open flames as it is likely flammable. Keep it in a tightly sealed container to prevent leakage. Separate it from oxidizing agents and incompatible substances. Store in accordance with local regulations for chemical storage. |
| Shipping | Shipping of "Benzene, 1 - chloro - 4 - (methoxymethoxy) - 2 - methyl -" requires strict compliance with hazardous chemical regulations. It should be properly packaged in suitable containers, labeled clearly, and transported by carriers authorized for such chemicals. |
Competitive Benzene,1-Chloro-4-(Methoxymethoxy)-2-Methyl- prices that fit your budget—flexible terms and customized quotes for every order.
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What is the specific meaning of the chemical name of this product, Benzene, 1-chloro-4- (methoxymethoxy) -2-methyl-
The compound is called 1-chloro-4- (methoxymethoxy) -2-methylbenzene. "1-chlorine" indicates that there is a chlorine atom attached to the benzene ring at position 1, and the chlorine atom exists as a substituent on the benzene ring. "4- (methoxymethoxy) " means that there is a methoxymethoxy group attached to the benzene ring at position 4. Methoxymethoxy is a more complex substituent formed by the connection of one methoxy group (-OCH) to the oxygen atom of another methoxy group, which has a specific impact on the physical and chemical properties of the compound. "2-methyl" indicates the presence of a methyl group (-CH) at position 2 of the benzene ring. The methyl group, as a power supply group, affects the electron cloud density of the benzene ring, which in turn affects the reactivity and other properties of the compound. These substituents at different positions jointly determine the unique chemical properties and reactivity of this compound, making it show specific uses and reaction characteristics in many fields such as organic synthesis and medicinal chemistry.
What are the main physical properties of this product, Benzene, 1-chloro-4- (methoxymethoxy) -2-methyl-
This compound, named 1-chloro-4- (methoxymethoxy) -2-methylbenzene, has many important physical properties. Its appearance is usually colorless to light yellow liquid, with a pure and uniform texture, good light transmission, and no obvious impurities or turbidity.
Smell, often emits a special aromatic smell, which is different from common phenyl series, with a unique smell endowed by ether structure, and can be initially identified by smell in specific environments.
When it comes to boiling point, it is generally between 180 and 200 ° C affected by benzene rings and their associated substituents. Due to the introduction of chlorine atoms, methoxy methoxy groups and methyl groups, the intermolecular forces change, and the boiling point of benzene is greatly increased. The higher boiling point makes it stable in liquid state at room temperature and pressure. When it involves operations such as heating or distillation, the temperature needs to be strictly controlled.
Melting point is roughly in the range of -10 ° C to 0 ° C. Molecular structural symmetry and the spatial distribution of substituents determine the melting point. The distribution of substituents on the benzene ring of the compound results in a decrease in molecular symmetry, and the melting point is significantly lower than that of benzene. This melting point characteristic makes it possible to solidify in a low temperature environment. Pay attention to temperature control when using and storing.
The density is about 1.1 - 1.2 g/cm ³, which is heavier than water. When mixed with water, it will sink to the bottom of the water. This property is of great significance in chemical operations such as separation and extraction and environmental pollution treatment.
In terms of solubility, it is slightly soluble in water. Due to the non-polar benzene ring and the weak polarity of methoxy methoxy group, it is very different from water polarity, which hinders its dissolution in water. However, it is soluble in common organic solvents, such as ethanol, ether, acetone, etc., and is used as a reactant or solvent in organic synthesis. Choosing a suitable organic solvent has a significant impact on the reaction process and product separation and purification.
Smell, often emits a special aromatic smell, which is different from common phenyl series, with a unique smell endowed by ether structure, and can be initially identified by smell in specific environments.
When it comes to boiling point, it is generally between 180 and 200 ° C affected by benzene rings and their associated substituents. Due to the introduction of chlorine atoms, methoxy methoxy groups and methyl groups, the intermolecular forces change, and the boiling point of benzene is greatly increased. The higher boiling point makes it stable in liquid state at room temperature and pressure. When it involves operations such as heating or distillation, the temperature needs to be strictly controlled.
Melting point is roughly in the range of -10 ° C to 0 ° C. Molecular structural symmetry and the spatial distribution of substituents determine the melting point. The distribution of substituents on the benzene ring of the compound results in a decrease in molecular symmetry, and the melting point is significantly lower than that of benzene. This melting point characteristic makes it possible to solidify in a low temperature environment. Pay attention to temperature control when using and storing.
The density is about 1.1 - 1.2 g/cm ³, which is heavier than water. When mixed with water, it will sink to the bottom of the water. This property is of great significance in chemical operations such as separation and extraction and environmental pollution treatment.
In terms of solubility, it is slightly soluble in water. Due to the non-polar benzene ring and the weak polarity of methoxy methoxy group, it is very different from water polarity, which hinders its dissolution in water. However, it is soluble in common organic solvents, such as ethanol, ether, acetone, etc., and is used as a reactant or solvent in organic synthesis. Choosing a suitable organic solvent has a significant impact on the reaction process and product separation and purification.
In which fields is this product used? Benzene, 1-chloro-4- (methoxymethoxy) -2-methyl-
This substance is called 1-chloro-4- (methoxymethoxy) -2-methylbenzene and is used in many fields.
In the field of organic synthesis, it is often used as a key intermediate. The chlorine atom, methoxymethoxy group and methyl group in the guain molecule all have unique reactivity. Chlorine atoms can participate in nucleophilic substitution reactions and can react with various nucleophilic reagents, such as alkoxides and amines, thereby introducing different functional groups and expanding the molecular structure. Methoxymethoxy, as a protective group, can protect hydroxyl and other functional groups in specific reactions, and then remove them after the reaction is completed to ensure that the reaction occurs accurately at the expected position. Methyl groups affect the electron cloud density and steric resistance of the benzene ring, which in turn affects the reactivity and selectivity of the entire molecule. With these properties, it plays a pivotal role in the synthesis of complex organic compounds, such as drugs and natural products.
In the field of materials science, polymer materials with special properties can be prepared through a series of reactions with this substance as the starting material. For example, by polymerizing with monomers containing unsaturated bonds, polymers with specific photoelectric properties can be obtained, or this structure can be introduced into the side chain to endow the material with unique solubility and thermal stability, providing more possibilities for the development of new functional materials.
In the field of pharmaceutical chemistry, the combination of functional groups in its structure may interact with specific targets in organisms. After rational structural modification and optimization, it is expected to develop drug molecules with specific pharmacological activities, such as antibacterial, anti-inflammatory, anti-tumor and other drugs, providing an important basis for the development of new drugs.
In summary, 1-chloro-4- (methoxymethoxy) -2-methylbenzene has shown extensive application prospects in organic synthesis, materials science, medicinal chemistry and other fields, and is of great significance to promote the development of related fields.
In the field of organic synthesis, it is often used as a key intermediate. The chlorine atom, methoxymethoxy group and methyl group in the guain molecule all have unique reactivity. Chlorine atoms can participate in nucleophilic substitution reactions and can react with various nucleophilic reagents, such as alkoxides and amines, thereby introducing different functional groups and expanding the molecular structure. Methoxymethoxy, as a protective group, can protect hydroxyl and other functional groups in specific reactions, and then remove them after the reaction is completed to ensure that the reaction occurs accurately at the expected position. Methyl groups affect the electron cloud density and steric resistance of the benzene ring, which in turn affects the reactivity and selectivity of the entire molecule. With these properties, it plays a pivotal role in the synthesis of complex organic compounds, such as drugs and natural products.
In the field of materials science, polymer materials with special properties can be prepared through a series of reactions with this substance as the starting material. For example, by polymerizing with monomers containing unsaturated bonds, polymers with specific photoelectric properties can be obtained, or this structure can be introduced into the side chain to endow the material with unique solubility and thermal stability, providing more possibilities for the development of new functional materials.
In the field of pharmaceutical chemistry, the combination of functional groups in its structure may interact with specific targets in organisms. After rational structural modification and optimization, it is expected to develop drug molecules with specific pharmacological activities, such as antibacterial, anti-inflammatory, anti-tumor and other drugs, providing an important basis for the development of new drugs.
In summary, 1-chloro-4- (methoxymethoxy) -2-methylbenzene has shown extensive application prospects in organic synthesis, materials science, medicinal chemistry and other fields, and is of great significance to promote the development of related fields.
What are the preparation methods of this product, Benzene, 1-chloro-4- (methoxymethoxy) -2-methyl-
To prepare this substance, namely 1-chloro-4- (methoxymethoxy) -2-methylbenzene, the following method can be followed.
First, use a suitable halogenated reagent, such as thionyl chloride or phosphorus trichloride, to halogenate the corresponding alcohol hydroxyl group, thereby introducing chlorine atoms. This process requires attention to the reaction conditions, such as temperature, solvent selection, etc. If the temperature is too high, side reactions may occur; the polarity of the solvent also affects the rate and selectivity of the reaction. The choice of non-polar solvents, such as dichloromethane, may facilitate the reaction.
Second, for the introduction of methoxy methoxy groups, methoxy methyl halide can be prepared first, and then nucleophilic substitution reaction occurs with compounds containing phenolic hydroxyl groups. This reaction may require the catalysis of bases, such as potassium carbonate, etc., to enhance the nucleophilicity of phenolic hydroxyl groups. And the reaction needs to be fully stirred to make the reactants evenly mixed to improve the efficiency of the reaction.
Third, for the introduction of methyl groups, the common method is Fu-gram alkylation reaction. Halogenated methane and anhydrous aluminum trichloride and other Lewis acids can be used as catalysts to react at an appropriate temperature. However, the Fu-Ke reaction is prone to the drawback of multiple substitutions, so it is necessary to precisely control the ratio of reactants and the reaction time to obtain a higher yield of the target product.
When operating, safety procedures should be strictly followed, and the reagents used are toxic and corrosive, and must be properly protected. And after the reaction is completed, the separation and purification of the product is also key. Pure 1-chloro-4 - (methoxymethoxy) -2-methylbenzene can be obtained by distillation, column chromatography, etc.
First, use a suitable halogenated reagent, such as thionyl chloride or phosphorus trichloride, to halogenate the corresponding alcohol hydroxyl group, thereby introducing chlorine atoms. This process requires attention to the reaction conditions, such as temperature, solvent selection, etc. If the temperature is too high, side reactions may occur; the polarity of the solvent also affects the rate and selectivity of the reaction. The choice of non-polar solvents, such as dichloromethane, may facilitate the reaction.
Second, for the introduction of methoxy methoxy groups, methoxy methyl halide can be prepared first, and then nucleophilic substitution reaction occurs with compounds containing phenolic hydroxyl groups. This reaction may require the catalysis of bases, such as potassium carbonate, etc., to enhance the nucleophilicity of phenolic hydroxyl groups. And the reaction needs to be fully stirred to make the reactants evenly mixed to improve the efficiency of the reaction.
Third, for the introduction of methyl groups, the common method is Fu-gram alkylation reaction. Halogenated methane and anhydrous aluminum trichloride and other Lewis acids can be used as catalysts to react at an appropriate temperature. However, the Fu-Ke reaction is prone to the drawback of multiple substitutions, so it is necessary to precisely control the ratio of reactants and the reaction time to obtain a higher yield of the target product.
When operating, safety procedures should be strictly followed, and the reagents used are toxic and corrosive, and must be properly protected. And after the reaction is completed, the separation and purification of the product is also key. Pure 1-chloro-4 - (methoxymethoxy) -2-methylbenzene can be obtained by distillation, column chromatography, etc.
What is the market outlook for this product, Benzene, 1-chloro-4- (methoxymethoxy) -2-methyl-
The research on the market prospect of 1-chloro-4- (methoxymethoxy) -2-methylbenzene is related to many factors.
Observing the market status of the past, this product is emerging in a specific field. In the past, in the field of fine chemicals, some processes required it. Because of its unique structure, it can be used as a key intermediate in some organic synthesis steps. The combination of methoxymethoxy and chlorine atoms and methyl groups endows it with special reactivity and can show specific effects when catalyzing reactions or building complex organic molecular structures.
Looking at the current situation, with the advancement of chemical technology, many new processes are emerging. Some cutting-edge organic synthesis routes require increasingly high purity and structural accuracy of reaction raw materials. Due to its unique structure, this product meets some high-end synthesis needs, so the demand in the high-end fine chemical market is on the rise. Furthermore, in the field of pharmaceutical research and development, the synthesis path of some innovative drugs has also gradually paid attention to this product, or because it can help build the skeleton of specific drug molecules and contribute to the creation of new drugs, the demand for it in the pharmaceutical intermediate market has also increased.
Looking to the future, science and technology continue to advance, and the chemical and pharmaceutical industries will continue to innovate. With the deepening of the concept of green chemistry, the requirements for environmental protection and atomic economy in the product synthesis process are becoming stricter. If this product can meet green chemistry standards in the synthesis process, optimize the synthesis path, reduce waste generation, and improve atomic utilization, it will be able to expand the market space. And with the vigorous development of new material research and development, new uses for this product may be tapped in the field of material precursors. Over time, if an efficient and low-cost large-scale production process is developed and production costs are reduced, it will be able to come out on top in the market competition, and the future may be bright. However, it should also be noted that the market competition is fierce, and similar alternative products may emerge at any time. If we cannot continue to innovate and stabilize our own advantages, the future will remain uncertain.
Observing the market status of the past, this product is emerging in a specific field. In the past, in the field of fine chemicals, some processes required it. Because of its unique structure, it can be used as a key intermediate in some organic synthesis steps. The combination of methoxymethoxy and chlorine atoms and methyl groups endows it with special reactivity and can show specific effects when catalyzing reactions or building complex organic molecular structures.
Looking at the current situation, with the advancement of chemical technology, many new processes are emerging. Some cutting-edge organic synthesis routes require increasingly high purity and structural accuracy of reaction raw materials. Due to its unique structure, this product meets some high-end synthesis needs, so the demand in the high-end fine chemical market is on the rise. Furthermore, in the field of pharmaceutical research and development, the synthesis path of some innovative drugs has also gradually paid attention to this product, or because it can help build the skeleton of specific drug molecules and contribute to the creation of new drugs, the demand for it in the pharmaceutical intermediate market has also increased.
Looking to the future, science and technology continue to advance, and the chemical and pharmaceutical industries will continue to innovate. With the deepening of the concept of green chemistry, the requirements for environmental protection and atomic economy in the product synthesis process are becoming stricter. If this product can meet green chemistry standards in the synthesis process, optimize the synthesis path, reduce waste generation, and improve atomic utilization, it will be able to expand the market space. And with the vigorous development of new material research and development, new uses for this product may be tapped in the field of material precursors. Over time, if an efficient and low-cost large-scale production process is developed and production costs are reduced, it will be able to come out on top in the market competition, and the future may be bright. However, it should also be noted that the market competition is fierce, and similar alternative products may emerge at any time. If we cannot continue to innovate and stabilize our own advantages, the future will remain uncertain.
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