Linshang Chemical
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Benzene, 1-Chloro-4-Nitroso- (8Ci)(9Ci)
Linshang Chemical
|
HS Code |
258198 |
| Chemical Formula | C6H4ClNO |
| Molecular Weight | 143.555 g/mol |
| Appearance | Typically solid, color may vary (usually with a yellowish - brown tint) |
| Boiling Point | Decomposes before boiling |
| Melting Point | Around 95 - 98 °C |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in many organic solvents like benzene, toluene |
| Vapor Pressure | Low at room temperature |
| Density | Approximately 1.32 g/cm³ |
| Stability | Unstable, especially in the presence of heat, light, or oxidizing agents |
| Odor | Pungent and characteristic |
As an accredited Benzene, 1-Chloro-4-Nitroso- (8Ci)(9Ci) factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100 - gram vial of 1 - chloro - 4 - nitroso - benzene (8CI, 9CI) with secure chemical - grade packaging. |
| Storage | 1 - Chloro - 4 - nitroso - benzene (8CI)(9CI) should be stored in a cool, well - ventilated area, away from heat sources and open flames. It must be kept in a tightly sealed container to prevent leakage and vapor release. Store it separately from oxidizing agents, reducing agents, and reactive chemicals to avoid potential hazardous reactions. |
| Shipping | 1 - Chloro - 4 - nitroso - benzene must be shipped in accordance with strict hazardous materials regulations. Use properly labeled, leak - proof containers. Ensure compliance with transport safety guidelines to prevent any release during transit. |
Competitive Benzene, 1-Chloro-4-Nitroso- (8Ci)(9Ci) prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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What are the chemical properties of 1 - chloro - 4 - nitroso - benzene?
1-Chloro-4-nitrosobenzene, this is an organic compound. Its chemical properties are unique, let me explain in detail for you.
First of all, it has strong reactivity. Nitroso (-NO) is an important functional group, and the electron cloud distribution of this group is special, which makes it easy to participate in many chemical reactions. For example, the nitrogen atom of the nitroso group is partially positively charged and can be used as an electrophilic reagent to react with electron-rich systems. Compounds containing active hydrogen, such as phenols and amines, can undergo condensation reactions with them to form nitrogen-containing heterocycles or azo-like compounds.
Furthermore, halogen atoms (chlorine) also affect their properties. The chlorine atom has an electron-absorbing induction effect, which can reduce the electron cloud density of the benzene ring and reduce the activity of the electrophilic substitution reaction of the benzene ring, especially it is not conducive to the attack of the ortho and para-sites of the electrophilic reagents. However, in the nucleophilic substitution reaction, the chlorine atom can act as a leaving group, and under appropriate nucleophilic reagents and reaction conditions, it can be replaced by nucleophilic reagents, such as reacting with sodium alcohol and ammonia, etc., to form ether and amine derivatives respectively.
In addition, 1-chloro-4-nitrosobenzene also performs prominently in the redox reaction. Nitroso can be oxidized to nitro (-NO 2) or reduced to amino (-NH 2). Under different redox conditions, different products can be obtained
In the field of organic synthesis, 1-chloro-4-nitrosobenzene is often used as a key intermediate. Through the above reactions, organic compounds with complex structures and different functions are synthesized, which are widely used in medicinal chemistry, materials science and other fields.
First of all, it has strong reactivity. Nitroso (-NO) is an important functional group, and the electron cloud distribution of this group is special, which makes it easy to participate in many chemical reactions. For example, the nitrogen atom of the nitroso group is partially positively charged and can be used as an electrophilic reagent to react with electron-rich systems. Compounds containing active hydrogen, such as phenols and amines, can undergo condensation reactions with them to form nitrogen-containing heterocycles or azo-like compounds.
Furthermore, halogen atoms (chlorine) also affect their properties. The chlorine atom has an electron-absorbing induction effect, which can reduce the electron cloud density of the benzene ring and reduce the activity of the electrophilic substitution reaction of the benzene ring, especially it is not conducive to the attack of the ortho and para-sites of the electrophilic reagents. However, in the nucleophilic substitution reaction, the chlorine atom can act as a leaving group, and under appropriate nucleophilic reagents and reaction conditions, it can be replaced by nucleophilic reagents, such as reacting with sodium alcohol and ammonia, etc., to form ether and amine derivatives respectively.
In addition, 1-chloro-4-nitrosobenzene also performs prominently in the redox reaction. Nitroso can be oxidized to nitro (-NO 2) or reduced to amino (-NH 2). Under different redox conditions, different products can be obtained
In the field of organic synthesis, 1-chloro-4-nitrosobenzene is often used as a key intermediate. Through the above reactions, organic compounds with complex structures and different functions are synthesized, which are widely used in medicinal chemistry, materials science and other fields.
What are the main uses of 1-chloro-4-nitrosobenzene?
1-Chloro-4-acetylbenzene, also known as p-chloroacetophenone, is one of the organic compounds. It has a wide range of uses and has important applications in many fields.
In the field of organic synthesis, this compound is a key intermediate. Due to the activity of chlorine atoms and acetyl groups in its structure, it can participate in many chemical reactions to synthesize a series of organic compounds with different structures. For example, by nucleophilic substitution, chlorine atoms can be replaced by many nucleophiles, and then new carbon-heteroatomic bonds can be formed to synthesize compounds with specific functions. At the same time, acetyl groups can also undergo many reactions, such as reduction reactions, oxidation reactions, etc., providing the possibility for the synthesis of complex organic molecules.
In the field of medicinal chemistry, 1-chloro-4-acetylbenzene also plays an important role. It is used as a starting material or an important intermediate in the synthesis of many drugs. Studies have found that some compounds based on it exhibit unique biological activities, or have antibacterial and anti-inflammatory effects, providing an important direction and material basis for the development of new drugs.
In addition, in the field of materials science, this compound also has its uses. It can be used to prepare polymer materials with certain special properties. By introducing it into the polymer chain, the material is endowed with special physical and chemical properties, such as improving material solubility and thermal stability, so as to meet the requirements of material properties in different application scenarios.
In summary, 1-chloro-4-acetylbenzene, with its unique chemical structure, plays an indispensable role in the fields of organic synthesis, medicinal chemistry, and materials science, and is of great significance to the development of related fields.
In the field of organic synthesis, this compound is a key intermediate. Due to the activity of chlorine atoms and acetyl groups in its structure, it can participate in many chemical reactions to synthesize a series of organic compounds with different structures. For example, by nucleophilic substitution, chlorine atoms can be replaced by many nucleophiles, and then new carbon-heteroatomic bonds can be formed to synthesize compounds with specific functions. At the same time, acetyl groups can also undergo many reactions, such as reduction reactions, oxidation reactions, etc., providing the possibility for the synthesis of complex organic molecules.
In the field of medicinal chemistry, 1-chloro-4-acetylbenzene also plays an important role. It is used as a starting material or an important intermediate in the synthesis of many drugs. Studies have found that some compounds based on it exhibit unique biological activities, or have antibacterial and anti-inflammatory effects, providing an important direction and material basis for the development of new drugs.
In addition, in the field of materials science, this compound also has its uses. It can be used to prepare polymer materials with certain special properties. By introducing it into the polymer chain, the material is endowed with special physical and chemical properties, such as improving material solubility and thermal stability, so as to meet the requirements of material properties in different application scenarios.
In summary, 1-chloro-4-acetylbenzene, with its unique chemical structure, plays an indispensable role in the fields of organic synthesis, medicinal chemistry, and materials science, and is of great significance to the development of related fields.
What are the methods for preparing 1 - chloro - 4 - nitroso - benzene?
1-Chloro-4-nitrosobenzene, a method of preparation, is often obtained by a specific organic reaction. One method is to use the corresponding benzene derivative as the starting material and carefully prepare the reaction conditions. If p-chloroaniline is used as the initial material, it will undergo a diazotization reaction with suitable reagents and conditions, and then the diazonium salt will be converted into a nitroso compound. In this process, the diazotization reaction needs to be precisely controlled at temperature, usually in a low temperature environment, to prevent side reactions from clumping and resulting in impure products.
There are other methods, which can be prepared from other chlorine-containing and nitroso-containing compounds through clever group conversion reactions. This approach requires careful selection of reactants and catalysts to achieve efficient and highly selective synthesis.
When preparing, the choice of solvent is also critical. The right solvent can not only promote the reaction, but also have a significant impact on the purity and yield of the product. Polar organic solvents are often selected because they can effectively dissolve the reactants and help the reaction occur smoothly.
In addition, the monitoring of the reaction process is indispensable. By means of thin-layer chromatography, high-performance liquid chromatography, etc., the reaction progress can be observed in real time, and the reaction conditions can be adjusted in a timely manner to ensure that the reaction proceeds in the expected direction, so as to obtain high-purity 1-chloro-4-nitrosobenzene products.
There are other methods, which can be prepared from other chlorine-containing and nitroso-containing compounds through clever group conversion reactions. This approach requires careful selection of reactants and catalysts to achieve efficient and highly selective synthesis.
When preparing, the choice of solvent is also critical. The right solvent can not only promote the reaction, but also have a significant impact on the purity and yield of the product. Polar organic solvents are often selected because they can effectively dissolve the reactants and help the reaction occur smoothly.
In addition, the monitoring of the reaction process is indispensable. By means of thin-layer chromatography, high-performance liquid chromatography, etc., the reaction progress can be observed in real time, and the reaction conditions can be adjusted in a timely manner to ensure that the reaction proceeds in the expected direction, so as to obtain high-purity 1-chloro-4-nitrosobenzene products.
What should I pay attention to when storing and transporting 1-chloro-4-nitroso-benzene?
1-Chloro-4-nitroso-benzene (1-chloro-4-nitroso-benzene) is an organic compound with certain toxicity and potential danger. When storing and transporting, pay attention to the following points:
First, the storage place must be cool, dry and well ventilated. This is because the substance is heated or wet, it may cause decomposition, deterioration, and even generate harmful gases. If placed in a humid place, water vapor may interact with the substance, causing its chemical properties to change; high temperature environment may enhance the reactivity and increase the risk of explosion.
Second, it needs to be stored separately from oxidants, acids, bases, etc., and should not be mixed. 1-Chloro-4-nitrosobenzene is chemically active, in contact with oxidants, or reacts violently, causing fire and explosion; when it encounters acid and alkali, it may also react chemically, affecting the stability and safety of the substance.
Third, the storage container must be tightly sealed to prevent leakage. It is advisable to use corrosion-resistant materials to make the container, such as glass, specific plastics or metal materials (selected according to the characteristics of the substance). If the container is poorly sealed and the substance leaks, it will not only pollute the environment, but also harm health if people contact or inhale it.
Fourth, ensure that the container is fixed and stable during transportation to avoid collision and vibration. Vibration, collision, or damage to the container during transportation, causing material leakage. And transportation vehicles need to be equipped with corresponding emergency treatment equipment and protective equipment for emergencies.
Fifth, whether it is stored or transported, relevant regulations and safety standards must be strictly followed. Operators should be professionally trained to be familiar with the characteristics, hazards and emergency treatment methods of the substance. In this way, the safety of 1-chloro-4-nitrosobenzene storage and transportation can be ensured to avoid dangerous accidents.
First, the storage place must be cool, dry and well ventilated. This is because the substance is heated or wet, it may cause decomposition, deterioration, and even generate harmful gases. If placed in a humid place, water vapor may interact with the substance, causing its chemical properties to change; high temperature environment may enhance the reactivity and increase the risk of explosion.
Second, it needs to be stored separately from oxidants, acids, bases, etc., and should not be mixed. 1-Chloro-4-nitrosobenzene is chemically active, in contact with oxidants, or reacts violently, causing fire and explosion; when it encounters acid and alkali, it may also react chemically, affecting the stability and safety of the substance.
Third, the storage container must be tightly sealed to prevent leakage. It is advisable to use corrosion-resistant materials to make the container, such as glass, specific plastics or metal materials (selected according to the characteristics of the substance). If the container is poorly sealed and the substance leaks, it will not only pollute the environment, but also harm health if people contact or inhale it.
Fourth, ensure that the container is fixed and stable during transportation to avoid collision and vibration. Vibration, collision, or damage to the container during transportation, causing material leakage. And transportation vehicles need to be equipped with corresponding emergency treatment equipment and protective equipment for emergencies.
Fifth, whether it is stored or transported, relevant regulations and safety standards must be strictly followed. Operators should be professionally trained to be familiar with the characteristics, hazards and emergency treatment methods of the substance. In this way, the safety of 1-chloro-4-nitrosobenzene storage and transportation can be ensured to avoid dangerous accidents.
What are the effects of 1 - chloro - 4 - nitroso - benzene on the environment and human health?
1-Chloro-4-nitrosobenzene, this substance has various effects on the environment and human health.
At one end of the environment, it is quite toxic, and once released into nature, it can cause serious pollution. If it enters the water body, aquatic organisms bear the brunt. It may damage its organ functions, or disrupt its physiological metabolism, causing a large number of aquatic organisms to die, and disrupting the balance of the water ecology. And because of its high chemical stability, it is difficult to degrade in the water body, and it persists for a long time. If it enters the soil, it will change the chemical properties and microbial communities. Or cause soil fertility to decline, affect the uptake of nutrients and moisture by plant roots, hinder plant growth and development, and may also enrich through the food chain, harming organisms that feed on plants.
As for human health, 1-chloro-4-nitrosobenzene is quite threatening. After respiratory tract, skin contact or ingestion into the body, it may cause acute poisoning. Stimulate the respiratory tract, making people cough, asthma, breathing difficulties; act on the skin, can cause redness, swelling, itching, burning; if eaten by mistake, damage the digestive system, cause vomiting, abdominal pain, diarrhea and other diseases. Long-term exposure to this environment increases the risk of cancer. Because it is a clear carcinogen, it can cause gene mutations, interfere with the normal growth and regulation of cells, and cause abnormal cell proliferation, which in turn induces tumors and endangers life. Therefore, the use, production and discharge of 1-chloro-4-nitrosobenzene should be strictly controlled to prevent it from harming the environment and human health.
At one end of the environment, it is quite toxic, and once released into nature, it can cause serious pollution. If it enters the water body, aquatic organisms bear the brunt. It may damage its organ functions, or disrupt its physiological metabolism, causing a large number of aquatic organisms to die, and disrupting the balance of the water ecology. And because of its high chemical stability, it is difficult to degrade in the water body, and it persists for a long time. If it enters the soil, it will change the chemical properties and microbial communities. Or cause soil fertility to decline, affect the uptake of nutrients and moisture by plant roots, hinder plant growth and development, and may also enrich through the food chain, harming organisms that feed on plants.
As for human health, 1-chloro-4-nitrosobenzene is quite threatening. After respiratory tract, skin contact or ingestion into the body, it may cause acute poisoning. Stimulate the respiratory tract, making people cough, asthma, breathing difficulties; act on the skin, can cause redness, swelling, itching, burning; if eaten by mistake, damage the digestive system, cause vomiting, abdominal pain, diarrhea and other diseases. Long-term exposure to this environment increases the risk of cancer. Because it is a clear carcinogen, it can cause gene mutations, interfere with the normal growth and regulation of cells, and cause abnormal cell proliferation, which in turn induces tumors and endangers life. Therefore, the use, production and discharge of 1-chloro-4-nitrosobenzene should be strictly controlled to prevent it from harming the environment and human health.
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