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Benzene, 1-(Chloromethyl)-3,5-Bis(Methylsulfonyl)-

Linshang Chemical

Specifications

HS Code

856202

Chemical Formula C9H11ClO4S2
Molecular Weight 282.769 g/mol
Physical State At Room Temperature Solid
Solubility In Water Low solubility (due to non - polar benzene ring and hydrophobic groups)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Vapor Pressure Low (due to its solid state and relatively large molecular weight)

As an accredited Benzene, 1-(Chloromethyl)-3,5-Bis(Methylsulfonyl)- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1-(chloromethyl)-3,5-bis(methylsulfonyl)benzene in a sealed chemical - grade bottle.
Storage Store "Benzene, 1-(chloromethyl)-3,5-bis(methylsulfonyl)-" in a cool, dry, well - ventilated area away from heat, ignition sources, and incompatible substances. Keep it in a tightly closed container made of suitable material to prevent leakage. Due to its potential hazards, store it in a dedicated chemical storage facility following safety regulations.
Shipping Benzene, 1-(chloromethyl)-3,5-bis(methylsulfonyl)- is a chemical that must be shipped following strict hazardous material regulations. Packaging should be robust to prevent leakage, and proper labeling indicating its nature is crucial for safe transport.
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Benzene, 1-(Chloromethyl)-3,5-Bis(Methylsulfonyl)- Benzene, 1-(Chloromethyl)-3,5-Bis(Methylsulfonyl)-
General Information
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Frequently Asked Questions

As a leading Benzene, 1-(Chloromethyl)-3,5-Bis(Methylsulfonyl)- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of this product 1- (chloromethyl) -3,5-bis (methylsulfonyl) benzene
This substance (1- (methoxy) -3,5 -bis (ethoxy carbonyl) pyridine) is an important chemical in the field of organic synthesis. Its chemical properties are mainly exhibited at the following ends:
From a structural point of view, this molecule contains a pyridine ring, which is aromatic and has a stable conjugate system. This property makes the substance exhibit some commonality of aromatic compounds to a certain extent, such as some activity for electrophilic substitution reactions.
As far as substituents are concerned, the presence of methoxy and ethoxy carbonyl groups greatly affects the electron cloud distribution and spatial structure of the molecule. The electron cloud density of the pyridine ring can be increased by the lone pair of electrons of the oxygen atom to the electron donor of the pyridine ring, especially the adjacent and para-site effects. This electron donor effect makes the pyridine ring more susceptible to attack by electrophilic reagents, which in turn affects the reaction check point and activity.
Ethoxy carbonyl belongs to the electron-absorbing group, which reduces the electron cloud density of the pyridine ring through induction and conjugation effects. Diethoxy carbonyl at the 3,5-position makes the electron cloud distribution of the pyridine ring more uneven, which checks and balances the electron donor effect of the methoxy group. This change in the distribution of electron clouds allows the substance to exhibit unique reactivity and selectivity in specific reactions.
In addition, the ester structure of the ethoxycarbonyl group gives the substance the possibility of hydrolysis. Under acidic or basic conditions, the ethoxycarbonyl group can undergo hydrolysis to form the corresponding carboxylic acid or carboxylate. This hydrolysis property can be used as a reaction strategy in organic synthesis for the introduction of carboxyl groups or the construction of other carboxyl-containing compounds.
In terms of physical properties, the solubility of the molecule may exhibit special properties due to the simultaneous presence of polar methoxy, ethoxycarbonyl, and relatively non-polar pyridine rings. It may have some solubility in organic solvents such as alcohols, ethers, halogenated hydrocarbons, etc., while its solubility in water is relatively limited, which mainly depends on the polarity and solvation of the molecule as a whole.
The chemical properties of this substance (1- (methoxy) -3,5-bis (ethoxy carbonyl) pyridine) are rich and diverse, providing many potential reaction paths and application directions for organic synthesis and related chemical research.
1- (chloromethyl) -3,5-bis (methylsulfonyl) benzene is commonly used in which chemical reactions
1 - (cyanomethyl) -3,5 -bis (formylhydrazide) benzene, which is commonly used in many chemical reactions such as organic synthesis and drug development.
In the field of organic synthesis, it can be used as a key intermediate to build complex organic molecules. For example, in the synthesis of heterocyclic compounds, with its cyanomethyl and formylhydrazide groups, it can be cleverly interacted with other reagents under specific reaction conditions to achieve cyclization reactions and build various heterocyclic structures with biological activities or special functions. This is like a skilled craftsman using unique components to build exquisite and complex buildings.
In drug development, this compound also shows important value. Due to its specific chemical structure, it has potential biological activity and can interact with targets in organisms. Medicinal chemists often use this as a starting material to modify and optimize the structure to develop new drugs with higher activity and lower toxicity. It is like using existing blueprints and carefully improving them to create a good drug with excellent performance.
In the field of materials science, it is also involved. Through appropriate reactions, it can be introduced into polymer materials to give the material special properties, such as improving the thermal stability, mechanical properties or optical properties of the material. It is like injecting a unique "soul" into the material, making it have unique characteristics.
1- (cyanomethyl) -3,5-bis (formylhydrazide) benzene plays a key role in many chemical reactions, opening the door to many chemical research and applications, providing assistance for the development of organic synthesis, drug development and materials science.
What are the market application fields of 1- (chloromethyl) -3,5-bis (methylsulfonyl) benzene
1- (cyanomethyl) -3,5-bis (methylsulfonyl) pyridine, which has important applications in medicine, pesticides and other fields.
In the field of medicine, it can be used as a key intermediate for the synthesis of compounds with specific biological activities. Many drug research and development efforts have been made to use the unique chemical structure of this substance to construct drug molecules that exhibit high affinity and selectivity for specific disease targets. For example, in the development of anti-tumor drugs, scientists hope to obtain new drugs that can precisely act on key signaling pathways of tumor cells, thereby inhibiting tumor cell proliferation and inducing apoptosis through structural modification and modification.
In the field of pesticides, 1- (cyanomethyl) -3,5-bis (methylsulfonyl) pyridine can be used as a lead compound for the development of new pesticides. With its interference characteristics on the physiological processes of some pests or pathogens, high-efficiency, low-toxicity and environmentally friendly pesticide products have been developed. For example, for some common fungal diseases of crops, fungicides can be developed based on them, which can effectively inhibit the growth and reproduction of fungi, ensure the healthy growth of crops, and improve crop yield and quality.
What are the preparation methods of 1- (chloromethyl) -3,5-bis (methylsulfonyl) benzene?
To prepare 1 - (cyanomethyl) -3,5 - bis (formyloxy) benzene, the method is as follows:
First take a suitable reaction vessel, clean and dry to avoid impurities. Prepare the required raw materials and reagents, and the quality and quantity must be accurate.
One method can be started with the corresponding benzene derivative. Select a benzene compound containing a suitable substituent group, and introduce the cyanomethyl group through the cyanomethylation reaction. This reaction requires the selection of a suitable base, such as potassium carbonate, to promote the reaction. In organic solvents, such as N, N-dimethylformamide (DMF), the temperature is moderately controlled, generally between 50 and 80 ° C, stirred evenly, so that the reactants are fully contacted, and the intermediate containing cyanomethyl groups can be obtained after several reactions.
Then, the intermediate is formylated. Commonly used formylating reagents, such as formic anhydride or methyl chloroformate, etc. In an alkaline environment, such as the presence of pyridine, and then in an organic solvent such as dichloromethane, control the reaction temperature, about 0-25 ° C, slowly add formylating reagents dropwise, and continue to stir the reaction. After the reaction is completed, the product can be purified by post-processing, such as extraction, washing, drying, column chromatography, etc., to obtain 1- (cyanomethyl) -3,5-bis (formyloxy) benzene.
Another way is to first formyloxylate the benzene ring, and then introduce cyanomethyl. First, benzene derivatives and formylation reagents are formyloxygenated under similar conditions as above to obtain benzene-containing diformyloxy groups. After that, this substance is used as the substrate, and then cyanomethylation is carried out. The conditions are also as described above. After the same post-processing steps, the target product can also be obtained.
When operating, when strictly following the procedures, pay attention to safety, because the reagents used are often corrosive and toxic. And each step of the reaction requires fine temperature control, timing control and monitoring to maintain yield and purity.
What are the physical properties of 1- (chloromethyl) -3,5-bis (methylsulfonyl) benzene?
1-% (cyanomethyl) -3,5-bis (methylsulfonyl) benzene, this is an organic compound. Its physical properties are as follows:
Looking at its appearance, it usually shows a white to light yellow crystalline powder state. This form is quite common in many organic compounds due to intermolecular forces and crystallization habits. As for odor, the compound may have a slight special odor, but the significance of this odor often varies according to its purity and environmental conditions.
The melting point is experimentally determined to be in a specific temperature range. For this compound, this temperature range is the key node for the transformation of its solid state and liquid state, reflecting the strength of the intermolecular bonding force. The value of the melting point is crucial for the identification and purification of the compound, and can be used as an important indicator to determine its purity.
In terms of solubility, in organic solvents such as ethanol and acetone, the compound exhibits a certain solubility, which is attributed to the existence of appropriate interaction forces between its molecular structure and organic solvent molecules, such as van der Waals force, hydrogen bond, etc., so that the molecules can be uniformly dispersed in the solvent. However, in water, its solubility is relatively poor, mainly due to the poor matching of the polarity of the compound molecule and the polarity of the water molecule, which is difficult for the water molecule to effectively overcome the intermolecular forces of the compound and make it disperse in the aqueous phase.
The density of the compound is also an important physical property. Although the specific value will fluctuate slightly due to the fineness of the measurement conditions, it is generally within a certain range. The density property plays an indispensable role in the material storage, transportation and related process design of the compound, which is related to the safety and efficiency of operation.
The above physical properties are of great significance for in-depth understanding of the characteristics of 1-% (cyanomethyl) -3,5-bis (methylsulfonyl) benzene, and then its rational application in many fields such as organic synthesis and materials science.