Linshang Chemical
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Benzene, 1-(Chloromethyl)-3-Fluoro-5-(Trifluoromethyl)-
Linshang Chemical
|
HS Code |
784109 |
| Chemical Formula | C8H5ClF4 |
| Molar Mass | 214.57 g/mol |
| Solubility In Water | Expected to be low (organic compound with non - polar groups) |
| Logp | Positive value expected (hydrophobic due to non - polar groups) |
As an accredited Benzene, 1-(Chloromethyl)-3-Fluoro-5-(Trifluoromethyl)- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 1-(chloromethyl)-3-fluoro-5-(trifluoromethyl)benzene in a sealed chemical - grade bottle. |
| Storage | Store “Benzene, 1-(chloromethyl)-3-fluoro-5-(trifluoromethyl)-” in a cool, well - ventilated area, away from heat, sparks, and open flames due to its potential flammability. Keep it in a tightly - sealed container to prevent vapor release. Store separately from oxidizing agents and incompatible substances to avoid dangerous reactions. Use appropriate labeling for easy identification and safety. |
| Shipping | The chemical "Benzene, 1-(chloromethyl)-3-fluoro-5-(trifluoromethyl)-" is shipped in containers designed to prevent leakage. It follows strict hazardous material shipping regulations to ensure safe transportation. |
Competitive Benzene, 1-(Chloromethyl)-3-Fluoro-5-(Trifluoromethyl)- prices that fit your budget—flexible terms and customized quotes for every order.
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What is the main use of this product 1- (chloromethyl) -3-fluoro-5- (trifluoromethyl) benzene?
(This compound, 1- (methoxy) -3-alkyl-5- (trimethylsilyl) benzene, did not have this precise chemical nomenclature in ancient times, but its use can be understood from the perspective of similar functions.) This substance, according to today's chemical understanding, may have many applications in the field of organic synthesis. The specific groups in its structure enable chemists to use various reactions as key intermediates to prepare organic molecules with special properties and functions.
Looking at ancient books, although there is no direct record of this substance, there may be clues of similar chemical changes in alchemy, pharmaceuticals and other practices. The ancient alchemists, who wanted the elixir of longevity, often used gold stones and other substances as raw materials, and after burning and refining, they made it chemically transformed. Although its cognition and means are far less accurate than today, in the process, substances with similar structures and properties may have been generated.
In terms of pharmaceuticals, the ancient healers used natural medicines as the basis, processed and other treatments, or involved similar chemical synthesis steps. If this substance existed in the materials at that time, or because of its structural characteristics, it participated in the transformation and generation process of certain drug ingredients, which affected the activity and efficacy of the drug. As recorded in ancient Materia Medica, some drugs have better curative effect after special processing, or are related to similar chemical changes of this substance.
Or in the production of processes, such as the preparation of lacquer ware and pigments, specific chemical substances are required to adjust the properties. If this substance exists in related materials, or can change the color, texture and other characteristics, it will help to improve the quality of process products. Although it is difficult to say exactly how this object was used in ancient processes, it may have potential uses in similar processes based on chemical principles and historical process development.
Looking at ancient books, although there is no direct record of this substance, there may be clues of similar chemical changes in alchemy, pharmaceuticals and other practices. The ancient alchemists, who wanted the elixir of longevity, often used gold stones and other substances as raw materials, and after burning and refining, they made it chemically transformed. Although its cognition and means are far less accurate than today, in the process, substances with similar structures and properties may have been generated.
In terms of pharmaceuticals, the ancient healers used natural medicines as the basis, processed and other treatments, or involved similar chemical synthesis steps. If this substance existed in the materials at that time, or because of its structural characteristics, it participated in the transformation and generation process of certain drug ingredients, which affected the activity and efficacy of the drug. As recorded in ancient Materia Medica, some drugs have better curative effect after special processing, or are related to similar chemical changes of this substance.
Or in the production of processes, such as the preparation of lacquer ware and pigments, specific chemical substances are required to adjust the properties. If this substance exists in related materials, or can change the color, texture and other characteristics, it will help to improve the quality of process products. Although it is difficult to say exactly how this object was used in ancient processes, it may have potential uses in similar processes based on chemical principles and historical process development.
What are the physical properties of 1- (chloromethyl) -3-fluoro-5- (trifluoromethyl) benzene?
(1 - (methoxy) -3 -bromo-5- (tribromomethyl) benzene, the physical properties are as follows:
Its appearance is often white to light yellow crystalline powder. From the point of view of the melting point, the melting point is in a specific range, because the exact value needs to be accurately determined according to the experimental conditions, generally within a certain range. The boiling point also has a corresponding range, which will be affected by factors such as the surrounding environmental pressure.
In terms of solubility, it has a certain solubility in common organic solvents such as dichloromethane and chloroform, and can be well dispersed and dissolved in it; in water, the solubility is minimal and almost insoluble. This is determined by the characteristics of the groups in its molecular structure. Groups such as bromine and methoxy make the polarity of the molecule different from water, so it is difficult to dissolve in water.
In terms of density, it is slightly larger than that of water. The specific value needs to be determined by a professional density measuring instrument under specific temperature conditions.
In terms of stability, it is relatively stable in a normal temperature and pressure environment. However, if exposed to strong light, high temperature environment, or in contact with specific substances such as strong oxidants, chemical reactions may occur, resulting in structural changes. For example, in the presence of light and specific catalysts, its bromine atoms may undergo substitution reactions.
Due to its special structure, this substance is often used as an important intermediate in the field of organic synthesis. It can be used to construct more complex organic compound structures, providing key starting materials for many organic synthesis routes, and has potential applications in many fields such as medicine, pesticides, and materials science.)
Its appearance is often white to light yellow crystalline powder. From the point of view of the melting point, the melting point is in a specific range, because the exact value needs to be accurately determined according to the experimental conditions, generally within a certain range. The boiling point also has a corresponding range, which will be affected by factors such as the surrounding environmental pressure.
In terms of solubility, it has a certain solubility in common organic solvents such as dichloromethane and chloroform, and can be well dispersed and dissolved in it; in water, the solubility is minimal and almost insoluble. This is determined by the characteristics of the groups in its molecular structure. Groups such as bromine and methoxy make the polarity of the molecule different from water, so it is difficult to dissolve in water.
In terms of density, it is slightly larger than that of water. The specific value needs to be determined by a professional density measuring instrument under specific temperature conditions.
In terms of stability, it is relatively stable in a normal temperature and pressure environment. However, if exposed to strong light, high temperature environment, or in contact with specific substances such as strong oxidants, chemical reactions may occur, resulting in structural changes. For example, in the presence of light and specific catalysts, its bromine atoms may undergo substitution reactions.
Due to its special structure, this substance is often used as an important intermediate in the field of organic synthesis. It can be used to construct more complex organic compound structures, providing key starting materials for many organic synthesis routes, and has potential applications in many fields such as medicine, pesticides, and materials science.)
Is 1- (chloromethyl) -3-fluoro-5- (trifluoromethyl) benzene chemically stable?
The chemical properties of (a substance) 1- (methoxy) -3-bromo-5- (trifluoromethoxy) benzene are unique compared with ordinary benzene compounds. In this compound, both methoxy and trifluoromethoxy are electron-donating groups. Although the electron-donating capabilities are different, they have a significant impact on the electron cloud density of the benzene ring. Methoxy group forms p-π conjugation with benzene ring by virtue of its lone pair electron of oxygen atom, which increases the electron cloud density of benzene ring, especially at the ortho and para-sites. In trifluoromethoxy group, the fluorine atom is extremely negative and the electron-absorbing induction effect is very strong, but its oxygen atom can produce weak p-π conjugation with benzene ring, and the whole shows a weak electron supply effect.
And bromine atom, with strong electron-absorbing induction effect, will reduce the electron cloud density of benzene ring, and mainly affect the ortho and para-sites. The coexistence of multiple substituents makes the electron cloud distribution of this compound complex. Such an electron cloud distribution makes its chemical properties different from both simple benzene and single substituted benzene.
In the electrophilic substitution reaction, due to the relatively strong power of the methoxy group, the reaction check point may tend to be ortho and para-methoxy, but the influence of the bromine atom and the trifluoromethoxy group should not be underestimated, which will make the reaction selectivity complicated. In the oxidation, reduction and other reactions of this compound, the substituents will also affect the reaction process and products. Overall, its chemical properties are difficult to say stable due to the interaction of multiple substituents, and it exhibits various chemical behaviors under different reaction conditions.
And bromine atom, with strong electron-absorbing induction effect, will reduce the electron cloud density of benzene ring, and mainly affect the ortho and para-sites. The coexistence of multiple substituents makes the electron cloud distribution of this compound complex. Such an electron cloud distribution makes its chemical properties different from both simple benzene and single substituted benzene.
In the electrophilic substitution reaction, due to the relatively strong power of the methoxy group, the reaction check point may tend to be ortho and para-methoxy, but the influence of the bromine atom and the trifluoromethoxy group should not be underestimated, which will make the reaction selectivity complicated. In the oxidation, reduction and other reactions of this compound, the substituents will also affect the reaction process and products. Overall, its chemical properties are difficult to say stable due to the interaction of multiple substituents, and it exhibits various chemical behaviors under different reaction conditions.
Is the process for producing 1- (chloromethyl) -3-fluoro-5- (trifluoromethyl) benzene complicated?
Looking at the process of synthesizing 1- (chloromethyl) -3 -chloro-5- (trichloromethyl) benzene, its complexity cannot be hidden.
The synthesis of this compound requires careful selection from raw materials. The introduction of chloromethyl, trichloromethyl and other groups requires complicated steps and precise control. In the initial stage, to introduce chloromethyl, it is necessary to find suitable halogenating reagents and catalytic conditions to make the reaction proceed in the expected direction. If there is a slight difference in the pool, it is easy to cause side reactions to cluster and the product is impure.
When introducing 3-chlorine atoms, its positioning effect should be considered. It is necessary to avoid adverse effects on the introduced chloromethyl group, and to ensure the precise addition of chlorine atoms at specific positions in the benzene ring. In this process, the reaction temperature, reaction time, and the proportion of reactants are all key factors. Any factor that deviates from the optimal value may damage the reaction yield and purity.
The introduction of 5 - (trichloromethyl) is even more difficult. The special structure of trichloromethyl makes its reactivity and selectivity unique. It is not only necessary to overcome the influence of steric resistance, but also to ensure the stability and integrity of the entire molecular structure after multi-step reactions.
During the reaction process, the separation and purification steps should not be underestimated. Due to the formation of many by-products in multi-step reactions, how to effectively separate the target product 1- (chloromethyl) -3-chloro-5- (trichloromethyl) benzene requires delicate separation methods, such as extraction, distillation, recrystallization, etc., and each method needs to be skillfully combined according to the characteristics of the product and the properties of impurities.
In summary, the synthesis of 1- (chloromethyl) -3-chloro-5- (trichloromethyl) benzene is a complex process, requiring deep chemical foundation, rich practical experience and fine regulation of each reaction link to achieve high yield and purity.
The synthesis of this compound requires careful selection from raw materials. The introduction of chloromethyl, trichloromethyl and other groups requires complicated steps and precise control. In the initial stage, to introduce chloromethyl, it is necessary to find suitable halogenating reagents and catalytic conditions to make the reaction proceed in the expected direction. If there is a slight difference in the pool, it is easy to cause side reactions to cluster and the product is impure.
When introducing 3-chlorine atoms, its positioning effect should be considered. It is necessary to avoid adverse effects on the introduced chloromethyl group, and to ensure the precise addition of chlorine atoms at specific positions in the benzene ring. In this process, the reaction temperature, reaction time, and the proportion of reactants are all key factors. Any factor that deviates from the optimal value may damage the reaction yield and purity.
The introduction of 5 - (trichloromethyl) is even more difficult. The special structure of trichloromethyl makes its reactivity and selectivity unique. It is not only necessary to overcome the influence of steric resistance, but also to ensure the stability and integrity of the entire molecular structure after multi-step reactions.
During the reaction process, the separation and purification steps should not be underestimated. Due to the formation of many by-products in multi-step reactions, how to effectively separate the target product 1- (chloromethyl) -3-chloro-5- (trichloromethyl) benzene requires delicate separation methods, such as extraction, distillation, recrystallization, etc., and each method needs to be skillfully combined according to the characteristics of the product and the properties of impurities.
In summary, the synthesis of 1- (chloromethyl) -3-chloro-5- (trichloromethyl) benzene is a complex process, requiring deep chemical foundation, rich practical experience and fine regulation of each reaction link to achieve high yield and purity.
What are the precautions for the transportation and storage of 1- (chloromethyl) -3-fluoro-5- (trifluoromethyl) benzene?
For 1 - (cyanomethyl) - 3 - cyanomethyl - 5 - (tricyanomethyl) benzene, many precautions must be made clear during transportation and storage.
First, this is a chemical substance with special properties. When transporting, make sure that the container is well sealed. If the container is slightly damaged, the substance escapes, or causes contamination of the surrounding environment, and due to its own characteristics or chemical reactions with surrounding substances, causing dangerous changes.
Second, the storage place is also particular. Choose a dry, cool and ventilated place. Humid environment or cause reactions such as hydrolysis to change the chemical structure and properties of the substance. If the temperature is too high, it may also cause it to decompose, evaporate, and even cause serious accidents such as explosions. And if the ventilation is not good, once the substance evaporates, accumulates in the space, and encounters open flames, static electricity, etc., there is a risk of fire and explosion.
Furthermore, caution is required during handling. The operator is in front of appropriate protective equipment, such as protective clothing, gloves, goggles, etc. Because it may be toxic and corrosive, a little careless contact with the human body will cause damage to the skin, eyes, etc. And the handling action should be gentle to avoid violent vibration and collision to prevent damage to the container and material leakage.
In addition, transportation and storage places should be kept away from fire, heat sources and strong oxidants. If this substance comes into contact with a strong oxidizing agent, it is very likely to undergo a violent redox reaction, with unimaginable consequences. Fire and heat sources can easily increase the temperature of the substance, causing various dangerous situations.
In addition, at the storage place, obvious warning signs should be set up to inform everyone that the stored here are dangerous chemicals, and non-professionals should not approach. And it is necessary to be equipped with corresponding emergency treatment equipment and materials, such as fire extinguishers, adsorption materials, etc. In the event of an accident such as leakage, emergency treatment can be carried out in time to reduce the degree of harm.
First, this is a chemical substance with special properties. When transporting, make sure that the container is well sealed. If the container is slightly damaged, the substance escapes, or causes contamination of the surrounding environment, and due to its own characteristics or chemical reactions with surrounding substances, causing dangerous changes.
Second, the storage place is also particular. Choose a dry, cool and ventilated place. Humid environment or cause reactions such as hydrolysis to change the chemical structure and properties of the substance. If the temperature is too high, it may also cause it to decompose, evaporate, and even cause serious accidents such as explosions. And if the ventilation is not good, once the substance evaporates, accumulates in the space, and encounters open flames, static electricity, etc., there is a risk of fire and explosion.
Furthermore, caution is required during handling. The operator is in front of appropriate protective equipment, such as protective clothing, gloves, goggles, etc. Because it may be toxic and corrosive, a little careless contact with the human body will cause damage to the skin, eyes, etc. And the handling action should be gentle to avoid violent vibration and collision to prevent damage to the container and material leakage.
In addition, transportation and storage places should be kept away from fire, heat sources and strong oxidants. If this substance comes into contact with a strong oxidizing agent, it is very likely to undergo a violent redox reaction, with unimaginable consequences. Fire and heat sources can easily increase the temperature of the substance, causing various dangerous situations.
In addition, at the storage place, obvious warning signs should be set up to inform everyone that the stored here are dangerous chemicals, and non-professionals should not approach. And it is necessary to be equipped with corresponding emergency treatment equipment and materials, such as fire extinguishers, adsorption materials, etc. In the event of an accident such as leakage, emergency treatment can be carried out in time to reduce the degree of harm.
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