Linshang Chemical
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Benzene, 2-Chloro-4-Methoxy-1-Nitro-
Linshang Chemical
|
HS Code |
180398 |
| Chemical Formula | C7H6ClNO3 |
| Molecular Weight | 187.58 |
| Appearance | Solid (Typical appearance description, actual may vary) |
| Solubility In Water | Low (General assumption, actual data required) |
| Solubility In Organic Solvents | Soluble in some organic solvents (General, actual data needed) |
As an accredited Benzene, 2-Chloro-4-Methoxy-1-Nitro- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 2 - chloro - 4 - methoxy - 1 - nitro - benzene in a sealed chemical - grade bottle. |
| Storage | Store "Benzene, 2 - chloro - 4 - methoxy - 1 - nitro -" in a cool, well - ventilated area away from heat, sparks, and open flames. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials. Separate it from oxidizing agents, reducing agents, and other incompatible substances to prevent potential reactions. |
| Shipping | The chemical "Benzene, 2 - chloro - 4 - methoxy - 1 - nitro -" should be shipped in accordance with hazardous material regulations. Use appropriate containers to prevent leakage, and ensure proper labeling for safe and compliant transportation. |
Competitive Benzene, 2-Chloro-4-Methoxy-1-Nitro- prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
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As a leading Benzene, 2-Chloro-4-Methoxy-1-Nitro- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the chemical properties of this product 2-chloro-4-methoxy-1-nitrobenzene?
The chemical properties of this substance, 2-cyano-4-methoxy-1-naphthylbenzene, are quite complex and unique.
Structurally, the cyano group (-CN) gives the substance a certain chemical activity. The carbon atom in the cyano group is connected to the nitrogen atom by a triple bond, which makes the cyano group have a strong electron-withdrawing ability. In chemical reactions, it is easy to participate in nucleophilic substitution reactions, because its electron-withdrawing properties can make the carbon atoms connected to it partially positively charged, thus attracting the attack of nucleophilic reagents. For example, in the presence of suitable nucleophilic reagents, the cyano group can be replaced by nucleophilic reagents to generate new compounds containing nitrogen or other functional groups. The presence of methoxy group (-OCH) also affects the chemical properties of the substance. Methoxy group is a power supply group, which forms p-π conjugation with the benzene ring through the lone pair electrons of its oxygen atom, which increases the electron cloud density on the benzene ring. This leads to more electrophilic substitution reactions in the benzene ring, and electrophilic reagents are more likely to attack the positions with higher electron cloud density on the benzene ring. For example, in electrophilic substitution reactions such as halogenation and nitrification, methoxy groups make the reactions mainly occur in its ortho and para-positions. The structure of
naphthalene provides a larger conjugate system, which makes the substance have certain stability. Large conjugated systems also affect their electronic transition properties. In terms of photophysics, they may exhibit specific absorption and emission spectra, which may be of potential value for some photochemical applications. Moreover, the spatial structure of the naphthylbenzene moiety also affects the interactions between molecules. For example, the spatial shape and steric resistance effects play a key role in crystal accumulation or the formation of supramolecular structures with other molecules.
Overall, 2-cyanogen-4-methoxy-1-naphthylbenzene has diverse chemical properties due to the synergy of different functional groups and structural parts, and may have potential applications and research values in many fields such as organic synthesis and materials science.
Structurally, the cyano group (-CN) gives the substance a certain chemical activity. The carbon atom in the cyano group is connected to the nitrogen atom by a triple bond, which makes the cyano group have a strong electron-withdrawing ability. In chemical reactions, it is easy to participate in nucleophilic substitution reactions, because its electron-withdrawing properties can make the carbon atoms connected to it partially positively charged, thus attracting the attack of nucleophilic reagents. For example, in the presence of suitable nucleophilic reagents, the cyano group can be replaced by nucleophilic reagents to generate new compounds containing nitrogen or other functional groups. The presence of methoxy group (-OCH) also affects the chemical properties of the substance. Methoxy group is a power supply group, which forms p-π conjugation with the benzene ring through the lone pair electrons of its oxygen atom, which increases the electron cloud density on the benzene ring. This leads to more electrophilic substitution reactions in the benzene ring, and electrophilic reagents are more likely to attack the positions with higher electron cloud density on the benzene ring. For example, in electrophilic substitution reactions such as halogenation and nitrification, methoxy groups make the reactions mainly occur in its ortho and para-positions. The structure of
naphthalene provides a larger conjugate system, which makes the substance have certain stability. Large conjugated systems also affect their electronic transition properties. In terms of photophysics, they may exhibit specific absorption and emission spectra, which may be of potential value for some photochemical applications. Moreover, the spatial structure of the naphthylbenzene moiety also affects the interactions between molecules. For example, the spatial shape and steric resistance effects play a key role in crystal accumulation or the formation of supramolecular structures with other molecules.
Overall, 2-cyanogen-4-methoxy-1-naphthylbenzene has diverse chemical properties due to the synergy of different functional groups and structural parts, and may have potential applications and research values in many fields such as organic synthesis and materials science.
What are the main applications of 2-chloro-4-methoxy-1-nitrobenzene?
2 + -Hydroxy-4-methoxy-1-naphthylbenzene has important applications in medicine, materials science and other fields.
In the field of medicine, this compound exhibits unique biological activity. Due to its special chemical structure, it may be used as a lead compound to assist drug development. By modifying and optimizing its structure, it is expected to create new drugs with high activity and selectivity. For example, in the research of anti-tumor drugs, it may inhibit the growth and proliferation of tumor cells by virtue of its effect on specific targets of tumor cells, providing new ideas for solving cancer problems. At the same time, in the research and development of drugs for the treatment of nervous system diseases, it may have a positive impact on the regulation of neurotransmitters and the protection of nerve cells, bringing hope for the treatment of Parkinson's disease, Alzheimer's disease and other diseases.
In the field of materials science, 2 + -hydroxy- 4-methoxy-1-naphthylbenzene can be used to prepare functional materials. Because of its specific optical and electrical properties, it can be applied to organic Light Emitting Diodes (OLEDs). In OLED manufacturing, it can be used as a light-emitting layer material to improve the luminous efficiency and color purity of OLEDs by virtue of its own luminous properties, so that the display screen presents a more gorgeous and realistic image. In addition, in the preparation of sensor materials, it can achieve highly sensitive detection of target substances based on physical or chemical changes that occur when they interact with specific substances, and play an important role in environmental monitoring, food safety testing, and other aspects.
In the field of medicine, this compound exhibits unique biological activity. Due to its special chemical structure, it may be used as a lead compound to assist drug development. By modifying and optimizing its structure, it is expected to create new drugs with high activity and selectivity. For example, in the research of anti-tumor drugs, it may inhibit the growth and proliferation of tumor cells by virtue of its effect on specific targets of tumor cells, providing new ideas for solving cancer problems. At the same time, in the research and development of drugs for the treatment of nervous system diseases, it may have a positive impact on the regulation of neurotransmitters and the protection of nerve cells, bringing hope for the treatment of Parkinson's disease, Alzheimer's disease and other diseases.
In the field of materials science, 2 + -hydroxy- 4-methoxy-1-naphthylbenzene can be used to prepare functional materials. Because of its specific optical and electrical properties, it can be applied to organic Light Emitting Diodes (OLEDs). In OLED manufacturing, it can be used as a light-emitting layer material to improve the luminous efficiency and color purity of OLEDs by virtue of its own luminous properties, so that the display screen presents a more gorgeous and realistic image. In addition, in the preparation of sensor materials, it can achieve highly sensitive detection of target substances based on physical or chemical changes that occur when they interact with specific substances, and play an important role in environmental monitoring, food safety testing, and other aspects.
What are the methods for preparing 2-chloro-4-methoxy-1-nitrobenzene?
To prepare 2-bromo-4-methoxy-1-naphthylbenzoic acid, the following ancient methods can be used.
First, start with the corresponding naphthol derivative. First, naphthol and halomethane are heated in an alkaline environment, such as potassium carbonate as a base, in a suitable solvent such as N, N-dimethylformamide (DMF), and nucleophilic substitution reactions occur, and methoxy groups can be introduced. The resulting methoxy naphthol product is then reacted with a brominating reagent such as liquid bromine in a dichloromethane solvent under the catalysis of an appropriate catalyst such as iron powder at a low temperature such as 0 ° C to 5 ° C to achieve the substitution of bromine atoms at the specified position. Naphthalene derivatives containing bromine and methoxy groups are obtained. Finally, through a suitable carboxylation reaction, such as using carbon dioxide as a carboxyl source, after a metal reagent such as magnesium forms a Grignard reagent, carbon dioxide is introduced and then acid hydrolyzed to obtain the target product.
Second, from another angle, the naphthalene ring can be brominated first. A bromine atom is introduced at a specific location in the naphthalene ring by heating and refluxing in a carbon tetrachloride solvent with a suitable brominating agent, such as N-bromosuccinimide (NBS), in the presence of an initiator such as benzoyl peroxide. After that, it is reacted with a halomethoxy reagent under basic conditions to attach a methoxy group. Finally, 2-bromo-4-methoxy-1-naphthalene benzoic acid is obtained by reacting with potassium cyanide or other carboxylation methods, such as reacting with potassium cyanide to form a nitrile group, which is then hydrolyzed to a carboxyl group.
Third, the naphthalene ring can also be constructed first. Using suitable aromatic raw materials, the naphthalene ring skeleton is formed by condensation means such as Fourier-gram reaction. During the construction process, the reaction sequence and conditions are rationally designed, and bromine atoms, methoxy groups and carboxyl-related groups are gradually introduced. For example, the benzene ring derivative of bromine atom and methoxy substituent is first introduced at a suitable position, and the naphthalene ring is formed by intramolecular condensation, and then the naphthalene ring is carboxylated to achieve the preparation of the target product.
First, start with the corresponding naphthol derivative. First, naphthol and halomethane are heated in an alkaline environment, such as potassium carbonate as a base, in a suitable solvent such as N, N-dimethylformamide (DMF), and nucleophilic substitution reactions occur, and methoxy groups can be introduced. The resulting methoxy naphthol product is then reacted with a brominating reagent such as liquid bromine in a dichloromethane solvent under the catalysis of an appropriate catalyst such as iron powder at a low temperature such as 0 ° C to 5 ° C to achieve the substitution of bromine atoms at the specified position. Naphthalene derivatives containing bromine and methoxy groups are obtained. Finally, through a suitable carboxylation reaction, such as using carbon dioxide as a carboxyl source, after a metal reagent such as magnesium forms a Grignard reagent, carbon dioxide is introduced and then acid hydrolyzed to obtain the target product.
Second, from another angle, the naphthalene ring can be brominated first. A bromine atom is introduced at a specific location in the naphthalene ring by heating and refluxing in a carbon tetrachloride solvent with a suitable brominating agent, such as N-bromosuccinimide (NBS), in the presence of an initiator such as benzoyl peroxide. After that, it is reacted with a halomethoxy reagent under basic conditions to attach a methoxy group. Finally, 2-bromo-4-methoxy-1-naphthalene benzoic acid is obtained by reacting with potassium cyanide or other carboxylation methods, such as reacting with potassium cyanide to form a nitrile group, which is then hydrolyzed to a carboxyl group.
Third, the naphthalene ring can also be constructed first. Using suitable aromatic raw materials, the naphthalene ring skeleton is formed by condensation means such as Fourier-gram reaction. During the construction process, the reaction sequence and conditions are rationally designed, and bromine atoms, methoxy groups and carboxyl-related groups are gradually introduced. For example, the benzene ring derivative of bromine atom and methoxy substituent is first introduced at a suitable position, and the naphthalene ring is formed by intramolecular condensation, and then the naphthalene ring is carboxylated to achieve the preparation of the target product.
What is the approximate market price of 2-chloro-4-methoxy-1-nitrobenzene?
"Tiangong Kaiwu" says: "To know the price of 2 + -alkane-4-methoxy-1-naphthyl in the market, this is a fine chemical product, and its price often varies depending on the purity of the quality and the supply and demand of the market. In today's city, if the quality and purity are excellent, the price may reach tens or even hundreds of gold per catty; if the quality is miscellaneous, the price will drop sharply, or only a few gold.
Gaiyin 2 + -alkane-4-methoxy-1-naphthyl is mostly used in various fine chemical processes, which are needed in the pharmaceutical and fragrance industries. If the market needs a lot, but the production is limited, the price will be high; if the production is more and less, the price will drop. And the difficulty of its production is also related to the price. If the process is complicated and the materials used are precious, the cost will be high and the price will be high. If the process is simple and the materials used are common, the price can be close to the people.
If you want to get an accurate price, you can know the current exact market price when you consult the merchants in the city, the owners of chemical workshops, or the trading places of chemical materials. "
Gaiyin 2 + -alkane-4-methoxy-1-naphthyl is mostly used in various fine chemical processes, which are needed in the pharmaceutical and fragrance industries. If the market needs a lot, but the production is limited, the price will be high; if the production is more and less, the price will drop. And the difficulty of its production is also related to the price. If the process is complicated and the materials used are precious, the cost will be high and the price will be high. If the process is simple and the materials used are common, the price can be close to the people.
If you want to get an accurate price, you can know the current exact market price when you consult the merchants in the city, the owners of chemical workshops, or the trading places of chemical materials. "
What are the precautions for storing and transporting 2-chloro-4-methoxy-1-nitrobenzene?
Fu 2 + -4-methylphenyl-1-naphthyl benzene, in the process of storage, there is a need to pay attention to it.
When it is stored, it is the first environment. Where things are dry and dry, avoid high tides. This is because high tides can cause its chemical activity, or cause decomposition and damage; tides are easy to make things invaded by water and destroy their chemical properties. And it is better to survive well, in order to prevent the accumulation of water and cause danger.
Furthermore, it is difficult to isolate fire sources and oxidize. This material is mostly flammable, burning in case of fire, or even exploding; oxidation can also cause strong reactions, endangering safety. The storage container is also very important. It is advisable to use a corrosion-resistant and well-sealed container to prevent leakage or external objects from reacting.
If it is not damaged, the package must be firm. Properly wrapped with suitable materials, it will cause less shock and collision. And the tools also need to be cleaned, dry, and other things that may be reversed. People are also familiar with the characteristics of this thing. In case of unexpected accidents, it can be properly used.
On the way, the degree of control is high. It can be maintained by refrigeration, preservation, etc. If you are in a place of inflammation and tides, you should be especially careful, and the whole product should be completed. In this case, the storage or storage should be done according to its chemical and physical properties, and the safety of the product can be guaranteed.
When it is stored, it is the first environment. Where things are dry and dry, avoid high tides. This is because high tides can cause its chemical activity, or cause decomposition and damage; tides are easy to make things invaded by water and destroy their chemical properties. And it is better to survive well, in order to prevent the accumulation of water and cause danger.
Furthermore, it is difficult to isolate fire sources and oxidize. This material is mostly flammable, burning in case of fire, or even exploding; oxidation can also cause strong reactions, endangering safety. The storage container is also very important. It is advisable to use a corrosion-resistant and well-sealed container to prevent leakage or external objects from reacting.
If it is not damaged, the package must be firm. Properly wrapped with suitable materials, it will cause less shock and collision. And the tools also need to be cleaned, dry, and other things that may be reversed. People are also familiar with the characteristics of this thing. In case of unexpected accidents, it can be properly used.
On the way, the degree of control is high. It can be maintained by refrigeration, preservation, etc. If you are in a place of inflammation and tides, you should be especially careful, and the whole product should be completed. In this case, the storage or storage should be done according to its chemical and physical properties, and the safety of the product can be guaranteed.
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