Linshang Chemical
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Benzeneacetic Acid, 2-Chloro-4-Methoxy-
Linshang Chemical
|
HS Code |
682650 |
| Chemical Formula | C9H9ClO3 |
| Molar Mass | 200.62 g/mol |
| Appearance | Solid (usually) |
| Physical State At Room Temp | Solid |
| Solubility In Water | Low solubility |
| Solubility In Organic Solvents | Soluble in some organic solvents |
| Melting Point | Specific value may vary, but in the range of organic solid melting points |
| Odor | May have a characteristic organic odor |
| Density | Data may be lacking, but likely in the range of typical organic solids |
| Acidity | Weakly acidic due to the carboxylic acid group |
| Stability | Stable under normal conditions, but may react under specific chemical environments |
As an accredited Benzeneacetic Acid, 2-Chloro-4-Methoxy- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 2 - chloro - 4 - methoxy - benzeneacetic acid packaged in a sealed plastic container. |
| Storage | Store “2 - chloro - 4 - methoxy - benzeneacetic acid” in a cool, dry, well - ventilated area away from heat and ignition sources. Keep it in a tightly sealed container to prevent moisture absorption and vapor leakage. Separate it from oxidizing agents, bases, and reactive substances. Label the storage clearly for easy identification and safety. |
| Shipping | 2 - chloro - 4 - methoxy - benzeneacetic acid is shipped in well - sealed containers, often in drums or bottles depending on quantity. It must adhere to strict hazardous chemical shipping regulations, ensuring proper handling to prevent spills and environmental/health risks. |
Competitive Benzeneacetic Acid, 2-Chloro-4-Methoxy- prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy Benzeneacetic Acid, 2-Chloro-4-Methoxy- in China?
As a trusted Benzeneacetic Acid, 2-Chloro-4-Methoxy- manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading Benzeneacetic Acid, 2-Chloro-4-Methoxy- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the chemical properties of 2-chloro-4-methoxyphenylacetic acid?
The chemical properties of 2 + -alkane-4-methoxyphenylacetic acid are quite unique. Among this compound, the groups connected to the 2-position and the 4-position give it a specific activity.
As far as its physical properties are concerned, it is in a solid state at room temperature or in a solid state. Due to the interaction between atoms in the molecule, it has a certain melting point and boiling point. When it is in a solid state, the crystal structure may be arranged regularly due to intermolecular forces.
When it comes to chemical activity, the carboxyl group (-COOH) contained in it shows acidic properties. This carboxyl group can neutralize with the base to form corresponding salts and water. In case of sodium hydroxide (NaOH), 2 + -alkane-4-methoxyphenyl acetate and water will be formed, which is a typical acid-base neutralization reaction.
Furthermore, the methoxyphenyl part of the molecule has certain stability due to the conjugation system of the benzene ring, but it also gives the molecule a certain lipophilicity. The substituents on the benzene ring affect the electron cloud density distribution of the benzene ring, which in turn affects its activity for electrophilic substitution reactions. For example, when encountering electrophilic reagents, substitution reactions can occur at specific positions of the benzene ring, and the reaction check point is affected by the localization effect of the substituents.
Although the alkane part is relatively stable in chemical properties, it affects the overall spatial structure and physical properties of the molecule, such as solubility. In organic solvents, due to the structure and polarity of the molecule as a whole, there may be certain differences in solubility. In short, 2 + -alkane-4-methoxyphenylacetic acid exhibits rich chemical properties due to the synergistic effect of the structure of each part.
As far as its physical properties are concerned, it is in a solid state at room temperature or in a solid state. Due to the interaction between atoms in the molecule, it has a certain melting point and boiling point. When it is in a solid state, the crystal structure may be arranged regularly due to intermolecular forces.
When it comes to chemical activity, the carboxyl group (-COOH) contained in it shows acidic properties. This carboxyl group can neutralize with the base to form corresponding salts and water. In case of sodium hydroxide (NaOH), 2 + -alkane-4-methoxyphenyl acetate and water will be formed, which is a typical acid-base neutralization reaction.
Furthermore, the methoxyphenyl part of the molecule has certain stability due to the conjugation system of the benzene ring, but it also gives the molecule a certain lipophilicity. The substituents on the benzene ring affect the electron cloud density distribution of the benzene ring, which in turn affects its activity for electrophilic substitution reactions. For example, when encountering electrophilic reagents, substitution reactions can occur at specific positions of the benzene ring, and the reaction check point is affected by the localization effect of the substituents.
Although the alkane part is relatively stable in chemical properties, it affects the overall spatial structure and physical properties of the molecule, such as solubility. In organic solvents, due to the structure and polarity of the molecule as a whole, there may be certain differences in solubility. In short, 2 + -alkane-4-methoxyphenylacetic acid exhibits rich chemical properties due to the synergistic effect of the structure of each part.
In which fields is 2-chloro-4-methoxyphenylacetic acid used?
2 + -Hydroxy- 4 -methoxyphenylacetic acid is useful in various fields.
In the field of medicine, this compound is a key raw material for the synthesis of traditional Chinese medicine. It contains special functional groups in its structure and can be used as a starting material for the synthesis of many drugs. By means of organic synthesis, drugs with specific pharmacological activities can be obtained through a series of reactions. If used to produce antibacterial and anti-inflammatory effects, it can act on the metabolic pathway of bacteria and prevent their growth and reproduction; it can also synthesize drugs that regulate immune function, help the body's immune system to function normally and resist diseases.
In the chemical industry, it is an important fine chemical. It can be used as an intermediary in the synthesis of fragrances. Due to its unique molecular structure, it can give fragrances a special aroma and stability. It can be used to prepare high-end perfumes and cosmetics fragrances, adding an elegant and charming fragrance. And in the manufacture of paints and inks, it can also be added to increase some properties of the product, such as color stability and durability.
In the field of agriculture, 2 + -hydroxy- 4-methoxyphenylacetic acid is also used. It can make plant growth regulators. Appropriate application can regulate plant growth, promote seed germination, root growth, and increase crop resistance, such as cold resistance, drought resistance, and pest resistance, thereby improving crop yield and quality.
In summary, 2 + -hydroxy- 4 -methoxyphenylacetic acid plays a significant role in the fields of medicine, chemical industry, agriculture, etc. With the progress of science and technology, its application prospects may be broader.
In the field of medicine, this compound is a key raw material for the synthesis of traditional Chinese medicine. It contains special functional groups in its structure and can be used as a starting material for the synthesis of many drugs. By means of organic synthesis, drugs with specific pharmacological activities can be obtained through a series of reactions. If used to produce antibacterial and anti-inflammatory effects, it can act on the metabolic pathway of bacteria and prevent their growth and reproduction; it can also synthesize drugs that regulate immune function, help the body's immune system to function normally and resist diseases.
In the chemical industry, it is an important fine chemical. It can be used as an intermediary in the synthesis of fragrances. Due to its unique molecular structure, it can give fragrances a special aroma and stability. It can be used to prepare high-end perfumes and cosmetics fragrances, adding an elegant and charming fragrance. And in the manufacture of paints and inks, it can also be added to increase some properties of the product, such as color stability and durability.
In the field of agriculture, 2 + -hydroxy- 4-methoxyphenylacetic acid is also used. It can make plant growth regulators. Appropriate application can regulate plant growth, promote seed germination, root growth, and increase crop resistance, such as cold resistance, drought resistance, and pest resistance, thereby improving crop yield and quality.
In summary, 2 + -hydroxy- 4 -methoxyphenylacetic acid plays a significant role in the fields of medicine, chemical industry, agriculture, etc. With the progress of science and technology, its application prospects may be broader.
What are the synthesis methods of 2-chloro-4-methoxyphenylacetic acid?
To prepare 2-hydroxy-4-methoxybenzoic acid, the following methods can be used:
First, p-methoxyphenol is used as the beginning, and p-methoxyphenylacetic acid is obtained by acylation reaction. In this step, the product can be obtained at a suitable temperature, usually between room temperature and 50 ° C. After carboxylation, p-methoxyphenylacetic acid is used as the substrate, and under specific reaction conditions, such as carbon dioxide atmosphere, in the presence of suitable catalysts, such as some transition metal catalysts, heated to a certain temperature, about 100-150 ° C, so that the carboxyl group is introduced into the appropriate position, then 2-hydroxy-4-methoxybenzoic acid is obtained.
Second, starting from p-methoxybenzaldehyde. First, through the condensation reaction of hydroxyaldehyde, with an aldehyde or ketone containing α-hydrogen, in a basic catalyst, such as a dilute solution of sodium hydroxide, at a low temperature, about 0-10 ° C, an intermediate product containing double bonds is formed. After the oxidation step, the double bond is oxidized and carboxylated with a suitable oxidizing agent, such as potassium permanganate or hydrogen peroxide, at an appropriate pH and temperature, about 40-60 ° C, to obtain the target product.
Third, m-methoxybenzoic acid is used as the raw material. First, the carboxyl group is protected, such as esterification with methanol, to obtain methyl m-methoxybenzoate. Then, through a halogenation reaction, a halogen atom is introduced at a specific position in the benzene ring, and a suitable halogenating agent, such as bromine or chlorine, is obtained at a certain temperature, about 50-80 ° C, under the catalysis of catalysts such as iron powder. Then through nucleophilic substitution reaction, with nucleophilic reagents such as sodium methoxide, the halogen atom is replaced by methoxy to obtain the corresponding methoxy substituent. Finally, hydrolysis to protect the group, catalyzed by acid or base, such as dilute hydrochloric acid or sodium hydroxide solution, heated and refluxed, about 80-100 ° C, to obtain 2-hydroxy-4-methoxybenzoic acid.
First, p-methoxyphenol is used as the beginning, and p-methoxyphenylacetic acid is obtained by acylation reaction. In this step, the product can be obtained at a suitable temperature, usually between room temperature and 50 ° C. After carboxylation, p-methoxyphenylacetic acid is used as the substrate, and under specific reaction conditions, such as carbon dioxide atmosphere, in the presence of suitable catalysts, such as some transition metal catalysts, heated to a certain temperature, about 100-150 ° C, so that the carboxyl group is introduced into the appropriate position, then 2-hydroxy-4-methoxybenzoic acid is obtained.
Second, starting from p-methoxybenzaldehyde. First, through the condensation reaction of hydroxyaldehyde, with an aldehyde or ketone containing α-hydrogen, in a basic catalyst, such as a dilute solution of sodium hydroxide, at a low temperature, about 0-10 ° C, an intermediate product containing double bonds is formed. After the oxidation step, the double bond is oxidized and carboxylated with a suitable oxidizing agent, such as potassium permanganate or hydrogen peroxide, at an appropriate pH and temperature, about 40-60 ° C, to obtain the target product.
Third, m-methoxybenzoic acid is used as the raw material. First, the carboxyl group is protected, such as esterification with methanol, to obtain methyl m-methoxybenzoate. Then, through a halogenation reaction, a halogen atom is introduced at a specific position in the benzene ring, and a suitable halogenating agent, such as bromine or chlorine, is obtained at a certain temperature, about 50-80 ° C, under the catalysis of catalysts such as iron powder. Then through nucleophilic substitution reaction, with nucleophilic reagents such as sodium methoxide, the halogen atom is replaced by methoxy to obtain the corresponding methoxy substituent. Finally, hydrolysis to protect the group, catalyzed by acid or base, such as dilute hydrochloric acid or sodium hydroxide solution, heated and refluxed, about 80-100 ° C, to obtain 2-hydroxy-4-methoxybenzoic acid.
What is the market price of 2-chloro-4-methoxyphenylacetic acid?
I don't know what the price of "2 + -deuterium-4-methoxybenzyloxycarbonyl amino acid" is in the city. However, to estimate its price, you need to understand many reasons.
First, the difficulty of this product is related to the price. If its production requires a lot of methods, materials and working hours, the price will be high. Like the ancient alchemy silver, the method is difficult and the production is small, and the price is high. If it is easy to make, the materials are wide and the workmanship is simple, the price will be low.
Second, the supply and demand of the city are also heavy. If there are many applicants, but there are few suppliers, the so-called "what is rare is expensive", the price will rise. It is still water in a dry time, although it is ordinary, the price is also high. On the contrary, if the supply exceeds the demand, the merchant wants to sell quickly, and the price will drop.
Third, the quality is related to the price. The superior is the best choice, the use is good, and the price may be higher than the inferior. Such as beautiful jade and stubborn stone, the quality is different but the price is heaven.
Fourth, the area and way of sale are different, and the price is also different. In prosperous cities, the tax is high and the fee is high, and the price may be higher in remote places. And through multi-business resale, the value is added layer by layer, and the price also rises.
It is difficult to determine the exact price of "2 + -deuterium-4 -methoxybenzyloxycarbonyl amino acid" in the market without the details of its system, supply and demand, quality and sales. To know the price, you should study the situation carefully, visit various merchants and consult various industry players, or you can get a more accurate price.
First, the difficulty of this product is related to the price. If its production requires a lot of methods, materials and working hours, the price will be high. Like the ancient alchemy silver, the method is difficult and the production is small, and the price is high. If it is easy to make, the materials are wide and the workmanship is simple, the price will be low.
Second, the supply and demand of the city are also heavy. If there are many applicants, but there are few suppliers, the so-called "what is rare is expensive", the price will rise. It is still water in a dry time, although it is ordinary, the price is also high. On the contrary, if the supply exceeds the demand, the merchant wants to sell quickly, and the price will drop.
Third, the quality is related to the price. The superior is the best choice, the use is good, and the price may be higher than the inferior. Such as beautiful jade and stubborn stone, the quality is different but the price is heaven.
Fourth, the area and way of sale are different, and the price is also different. In prosperous cities, the tax is high and the fee is high, and the price may be higher in remote places. And through multi-business resale, the value is added layer by layer, and the price also rises.
It is difficult to determine the exact price of "2 + -deuterium-4 -methoxybenzyloxycarbonyl amino acid" in the market without the details of its system, supply and demand, quality and sales. To know the price, you should study the situation carefully, visit various merchants and consult various industry players, or you can get a more accurate price.
What are the manufacturers of 2-chloro-4-methoxyphenylacetic acid?
Nowadays, there are many experts in the synthesis of 2-4-methoxyphenylacetic acid. The synthesis of this compound often requires fine technology and general materials.
First, there are those who start with benzene. First, benzene is used to replace the reaction, and a specific group is introduced. Multi-step reduction is required to carefully control the reaction components, such as the reaction degree and catalysis. In the reaction, it is necessary to observe the reaction rate, and to obtain the reaction rate at each step. The atoms on the benzene are gradually replaced by the desired groups, and the framework of the next order of molecules.
Second, there are also those who start with phenol compounds. The activity of phenols is high, and a series of reactions can be made. The methoxy group is first introduced, and then the carboxyl group and the alkyl group are introduced at the alkyl position. In this way, the inversion is particularly important. The inversion activity of phenols at different positions is high. If you want to make the inversion go in a specific direction, you can use the appropriate catalytic components.
Third, there are other aromatic compounds that can be synthesized from other aromatic compounds. With the wonderful methods of synthesis, such as combination inversion, addition inversion, etc., you can ingeniously reverse the way, and the parts of the group are inverted, so as to obtain 2-4-methoxy phenylacetic acid.
All these companies have a deep foundation in the field of synthesis, and there are many research in the field of synthesis. It can gain insight into the theory of inversion, use various chemical reactions, and seek the high efficiency of synthesis, so as to meet the needs of this compound in various fields such as chemical industry and chemical industry.
First, there are those who start with benzene. First, benzene is used to replace the reaction, and a specific group is introduced. Multi-step reduction is required to carefully control the reaction components, such as the reaction degree and catalysis. In the reaction, it is necessary to observe the reaction rate, and to obtain the reaction rate at each step. The atoms on the benzene are gradually replaced by the desired groups, and the framework of the next order of molecules.
Second, there are also those who start with phenol compounds. The activity of phenols is high, and a series of reactions can be made. The methoxy group is first introduced, and then the carboxyl group and the alkyl group are introduced at the alkyl position. In this way, the inversion is particularly important. The inversion activity of phenols at different positions is high. If you want to make the inversion go in a specific direction, you can use the appropriate catalytic components.
Third, there are other aromatic compounds that can be synthesized from other aromatic compounds. With the wonderful methods of synthesis, such as combination inversion, addition inversion, etc., you can ingeniously reverse the way, and the parts of the group are inverted, so as to obtain 2-4-methoxy phenylacetic acid.
All these companies have a deep foundation in the field of synthesis, and there are many research in the field of synthesis. It can gain insight into the theory of inversion, use various chemical reactions, and seek the high efficiency of synthesis, so as to meet the needs of this compound in various fields such as chemical industry and chemical industry.
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