Linshang Chemical
PRODUCTS
Benzeneacetic Acid, 3-Chloro-2-Nitro-
Linshang Chemical
|
HS Code |
438590 |
| Name | 3-Chloro-2-nitrobenzeneacetic acid |
| Chemical Formula | C8H6ClNO4 |
| Molar Mass | 215.59 g/mol |
| Appearance | Solid (usually a powder or crystalline solid) |
| Physical State At Room Temperature | Solid |
| Melting Point | Data may vary, typically in a specific temperature range |
| Solubility In Water | Low solubility in water |
| Solubility In Organic Solvents | Soluble in some organic solvents like ethanol, acetone |
| Density | Data may vary based on conditions |
| Acidity Pka | Specific pKa value relevant to its acidic nature |
| Hazard Class | May be classified as an irritant, toxicological data may vary |
As an accredited Benzeneacetic Acid, 3-Chloro-2-Nitro- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 3 - chloro - 2 - nitro - benzeneacetic acid packaged in a sealed plastic bottle. |
| Storage | Store "3 - chloro - 2 - nitro - benzeneacetic acid" in a cool, dry, well - ventilated area, away from heat sources and ignition sources. Keep it in a tightly closed container made of corrosion - resistant material, such as glass or certain plastics. Separate it from oxidizing agents, reducing agents, and bases to prevent chemical reactions. Label the storage container clearly for easy identification. |
| Shipping | 3 - chloro - 2 - nitro - benzeneacetic acid is shipped in accordance with hazardous chemical regulations. Packed in suitable containers to prevent leakage, transported by approved carriers with safety measures to ensure secure delivery. |
Competitive Benzeneacetic Acid, 3-Chloro-2-Nitro- prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy Benzeneacetic Acid, 3-Chloro-2-Nitro- in China?
As a trusted Benzeneacetic Acid, 3-Chloro-2-Nitro- manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading Benzeneacetic Acid, 3-Chloro-2-Nitro- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the physical properties of 3-chloro-2-nitrophenylacetic acid?
3-Bromo-2-fluorophenylacetic acid is one of the organic compounds. Its physical properties are unique and important in various fields such as organic synthesis.
Looking at its appearance, under normal temperature and pressure, it is mostly white to light yellow solid. This color feature is easy to distinguish, and the solid state has better stability and is conducive to storage and transportation. Its melting point and boiling point are also key physical properties. The melting point is about [specific melting point value]. At this temperature, the substance gradually melts from a solid state to a liquid state. The boiling point is related to the temperature at which it can be converted from a liquid state to a gas state, usually [specific boiling point value]. The characteristics of melting point and boiling point are important guidelines for separation, purification and control of reaction conditions.
Solubility is also one of its significant physical properties. In organic solvents, such as ethanol, ether, dichloromethane, etc., 3-bromo-2-fluorophenylacetic acid exhibits good solubility. This property makes it able to fully mix with many reactants in organic reaction systems, improving the rate and efficiency of the reaction. However, in water, its solubility is poor, and the hydrophobic aromatic ring structure accounts for a large proportion of its molecular structure, and the force between it and water molecules is weak.
In addition, the density of 3-bromo-2-fluorophenylacetic acid is also a physical constant. Its density is about [specific density value], which is of great significance for accurate measurement and the material ratio of the reaction system. At the same time, it has a certain smell. Although it is not strong and pungent, it also has a unique smell, which can be used as one of the auxiliary basis for identifying the substance.
In summary, the physical properties of 3-bromo-2-fluorophenylacetic acid, such as appearance, melting point, boiling point, solubility, density and odor, are related and have their own uses, laying the foundation for its application in chemical research, industrial production and other fields.
Looking at its appearance, under normal temperature and pressure, it is mostly white to light yellow solid. This color feature is easy to distinguish, and the solid state has better stability and is conducive to storage and transportation. Its melting point and boiling point are also key physical properties. The melting point is about [specific melting point value]. At this temperature, the substance gradually melts from a solid state to a liquid state. The boiling point is related to the temperature at which it can be converted from a liquid state to a gas state, usually [specific boiling point value]. The characteristics of melting point and boiling point are important guidelines for separation, purification and control of reaction conditions.
Solubility is also one of its significant physical properties. In organic solvents, such as ethanol, ether, dichloromethane, etc., 3-bromo-2-fluorophenylacetic acid exhibits good solubility. This property makes it able to fully mix with many reactants in organic reaction systems, improving the rate and efficiency of the reaction. However, in water, its solubility is poor, and the hydrophobic aromatic ring structure accounts for a large proportion of its molecular structure, and the force between it and water molecules is weak.
In addition, the density of 3-bromo-2-fluorophenylacetic acid is also a physical constant. Its density is about [specific density value], which is of great significance for accurate measurement and the material ratio of the reaction system. At the same time, it has a certain smell. Although it is not strong and pungent, it also has a unique smell, which can be used as one of the auxiliary basis for identifying the substance.
In summary, the physical properties of 3-bromo-2-fluorophenylacetic acid, such as appearance, melting point, boiling point, solubility, density and odor, are related and have their own uses, laying the foundation for its application in chemical research, industrial production and other fields.
What are the chemical properties of 3-chloro-2-nitrophenylacetic acid?
3-Bromo-2-aminophenylacetic acid is an organic compound with multiple chemical properties. Its molecules contain bromine atoms, amino groups and carboxyl groups, which give the compound unique reactivity.
From the perspective of halogenated hydrocarbons, bromine atoms are quite active. When encountering nucleophiles, nucleophilic substitution reactions are prone to occur. For example, in the presence of an appropriate base, alcohol nucleophiles can attack bromine atoms, and bromine ions leave to form corresponding ether compounds. This reaction mechanism provides electron pairs for nucleophiles to attack partially positively charged bromine atoms. After a transition state, old bonds break and new bonds form.
Amino groups are basic and nucleophilic. It can neutralize and react with acids to form corresponding salts. If it reacts with hydrochloric acid, amino nitrogen atoms provide lone pairs of electrons to bind protons to form ammonium salts. In addition, amino groups can participate in nucleophilic addition and substitution reactions. Taking the reaction with aldosterone as an example, amino nitrogen atoms nucleophilically attack aldosterone carbonyl carbon atoms and undergo a series of rearrangement and dehydration steps to form imines.
Carboxyl groups are acidic and can neutralize with bases to form carboxylate and water. If they react with sodium hydroxide, carboxyl groups provide protons and combine with hydroxide ions to form water, which itself becomes carboxyl negative ions. In the esterification reaction, carboxyl groups react with alcohols under acid catalysis to dehydrate to form esters. During the reaction, the acid catalyst makes the carboxyl carbonyl carbon atom more positively charged, which is conducive to the nucleophilic attack of the alcohol hydroxyl oxygen atom. Through the intermediate, it loses a molecule of water and forms an ester bond.
3-Bromo-2-aminophenylacetic acid has rich chemical properties due to the mutual influence of the functional groups it contains. It is widely used in the field of organic synthesis and can be used as a key intermediate for the preparation of various organic compounds such as drugs, pesticides and functional materials.
From the perspective of halogenated hydrocarbons, bromine atoms are quite active. When encountering nucleophiles, nucleophilic substitution reactions are prone to occur. For example, in the presence of an appropriate base, alcohol nucleophiles can attack bromine atoms, and bromine ions leave to form corresponding ether compounds. This reaction mechanism provides electron pairs for nucleophiles to attack partially positively charged bromine atoms. After a transition state, old bonds break and new bonds form.
Amino groups are basic and nucleophilic. It can neutralize and react with acids to form corresponding salts. If it reacts with hydrochloric acid, amino nitrogen atoms provide lone pairs of electrons to bind protons to form ammonium salts. In addition, amino groups can participate in nucleophilic addition and substitution reactions. Taking the reaction with aldosterone as an example, amino nitrogen atoms nucleophilically attack aldosterone carbonyl carbon atoms and undergo a series of rearrangement and dehydration steps to form imines.
Carboxyl groups are acidic and can neutralize with bases to form carboxylate and water. If they react with sodium hydroxide, carboxyl groups provide protons and combine with hydroxide ions to form water, which itself becomes carboxyl negative ions. In the esterification reaction, carboxyl groups react with alcohols under acid catalysis to dehydrate to form esters. During the reaction, the acid catalyst makes the carboxyl carbonyl carbon atom more positively charged, which is conducive to the nucleophilic attack of the alcohol hydroxyl oxygen atom. Through the intermediate, it loses a molecule of water and forms an ester bond.
3-Bromo-2-aminophenylacetic acid has rich chemical properties due to the mutual influence of the functional groups it contains. It is widely used in the field of organic synthesis and can be used as a key intermediate for the preparation of various organic compounds such as drugs, pesticides and functional materials.
What are the main uses of 3-chloro-2-nitrophenylacetic acid?
3-Bromo-2-aminophenylacetic acid is an important organic compound that has key uses in many fields such as medicine, pesticides, and materials.
In the field of medicine, it is an important pharmaceutical intermediate. It can be used to synthesize a variety of drugs through a series of chemical reactions. For example, for the treatment of specific diseases, the special structure of this compound can provide key support for drug activity. By modifying and modifying its structure, new drugs with better efficacy and less side effects can be developed, which makes great contributions to human health.
In the field of pesticides, 3-bromo-2-aminophenylacetic acid also plays an important role. It can be used as a key raw material for the synthesis of high-efficiency and low-toxicity pesticides. Its structural characteristics give pesticides unique properties, such as highly selective killing effects on specific pests, or can regulate plant growth, help increase crop production and income, while reducing the negative impact on the environment, and meet the needs of modern green agriculture development.
In the field of materials, this compound can participate in the synthesis of functional materials. With its special chemical properties, it can give materials special properties such as optics and electricity. For example, in the synthesis of organic optoelectronic materials, its participation can optimize material properties, improve the application efficiency of materials in optoelectronic devices, and promote the continuous progress of materials science. In conclusion, although 3-bromo-2-aminophenylacetic acid is an organic compound, it has shown great application value in many fields by virtue of its own structural characteristics, and plays an indispensable role in promoting the development of various fields.
In the field of medicine, it is an important pharmaceutical intermediate. It can be used to synthesize a variety of drugs through a series of chemical reactions. For example, for the treatment of specific diseases, the special structure of this compound can provide key support for drug activity. By modifying and modifying its structure, new drugs with better efficacy and less side effects can be developed, which makes great contributions to human health.
In the field of pesticides, 3-bromo-2-aminophenylacetic acid also plays an important role. It can be used as a key raw material for the synthesis of high-efficiency and low-toxicity pesticides. Its structural characteristics give pesticides unique properties, such as highly selective killing effects on specific pests, or can regulate plant growth, help increase crop production and income, while reducing the negative impact on the environment, and meet the needs of modern green agriculture development.
In the field of materials, this compound can participate in the synthesis of functional materials. With its special chemical properties, it can give materials special properties such as optics and electricity. For example, in the synthesis of organic optoelectronic materials, its participation can optimize material properties, improve the application efficiency of materials in optoelectronic devices, and promote the continuous progress of materials science. In conclusion, although 3-bromo-2-aminophenylacetic acid is an organic compound, it has shown great application value in many fields by virtue of its own structural characteristics, and plays an indispensable role in promoting the development of various fields.
What are the preparation methods of 3-chloro-2-nitrophenylacetic acid?
3-Bromo-2-aminobenzoic acid is an important intermediate in organic synthesis. There are many methods for preparation. The following is your detailed description.
First, the method of using anthranilic acid as the starting material. Dissolve anthranilic acid in an appropriate amount of organic solvent, such as dichloromethane, N, N-dimethylformamide, etc., and slowly add brominating reagents at low temperature and stirring. Common brominating reagents include bromine, N-bromosuccinimide (NBS), etc. If bromine is used, because it is active, the rate of dropwise addition must be slow to prevent excessive bromination. After dropwise addition, gradually heat up to a suitable temperature for reaction. This reaction requires attention to control the reaction temperature and the amount of brominating reagent, otherwise it is easy to generate polybrominated by-products. After the reaction, the product is purified by post-treatment, such as extraction, washing, drying, column chromatography or recrystallization.
Second, benzoic acid derivatives are used as the starting material. First, the benzene ring of benzoic acid is modified with a specific substituent, and a suitable guide group is introduced. This guide group can make the subsequent bromination reaction selectively occur at a specific location. Subsequently, the bromination reaction is carried out under suitable conditions. After the bromination is completed, the guide group is converted into an amino group through a specific reaction. There are many steps in this process, and each reaction requires precise control of the reaction conditions to ensure high yield and selectivity. For example, benzoic acid can be made into the corresponding amide first, and the guiding effect of the amide group can be used to make the bromination reaction preferentially occur in the ortho position, and then the amide group can be converted into an amino group through reactions such as Hoffmann degradation.
Third, it is prepared by the coupling reaction catalyzed by transition metals. Select suitable halogenated aromatics and reagents containing amino groups and carboxyl groups, and under the action of transition metal catalysts such as palladium catalysts, the coupling reaction occurs. This method requires the selection of suitable ligands to enhance the activity and selectivity of the catalyst, and requires strict anhydrous and anaerobic conditions of the reaction system. The reaction conditions are usually relatively mild, which can effectively construct carbon-carbon and carbon-heteroatomic bonds of the target molecule. However, the price of catalysts and ligands is often higher, and the cost is relatively large.
All preparation methods have their own advantages and disadvantages. In practical application, it is necessary to comprehensively weigh the availability of raw materials, cost considerations, product purity requirements and other factors to choose the most suitable method.
First, the method of using anthranilic acid as the starting material. Dissolve anthranilic acid in an appropriate amount of organic solvent, such as dichloromethane, N, N-dimethylformamide, etc., and slowly add brominating reagents at low temperature and stirring. Common brominating reagents include bromine, N-bromosuccinimide (NBS), etc. If bromine is used, because it is active, the rate of dropwise addition must be slow to prevent excessive bromination. After dropwise addition, gradually heat up to a suitable temperature for reaction. This reaction requires attention to control the reaction temperature and the amount of brominating reagent, otherwise it is easy to generate polybrominated by-products. After the reaction, the product is purified by post-treatment, such as extraction, washing, drying, column chromatography or recrystallization.
Second, benzoic acid derivatives are used as the starting material. First, the benzene ring of benzoic acid is modified with a specific substituent, and a suitable guide group is introduced. This guide group can make the subsequent bromination reaction selectively occur at a specific location. Subsequently, the bromination reaction is carried out under suitable conditions. After the bromination is completed, the guide group is converted into an amino group through a specific reaction. There are many steps in this process, and each reaction requires precise control of the reaction conditions to ensure high yield and selectivity. For example, benzoic acid can be made into the corresponding amide first, and the guiding effect of the amide group can be used to make the bromination reaction preferentially occur in the ortho position, and then the amide group can be converted into an amino group through reactions such as Hoffmann degradation.
Third, it is prepared by the coupling reaction catalyzed by transition metals. Select suitable halogenated aromatics and reagents containing amino groups and carboxyl groups, and under the action of transition metal catalysts such as palladium catalysts, the coupling reaction occurs. This method requires the selection of suitable ligands to enhance the activity and selectivity of the catalyst, and requires strict anhydrous and anaerobic conditions of the reaction system. The reaction conditions are usually relatively mild, which can effectively construct carbon-carbon and carbon-heteroatomic bonds of the target molecule. However, the price of catalysts and ligands is often higher, and the cost is relatively large.
All preparation methods have their own advantages and disadvantages. In practical application, it is necessary to comprehensively weigh the availability of raw materials, cost considerations, product purity requirements and other factors to choose the most suitable method.
What are the precautions for storing and transporting 3-chloro-2-nitrophenylacetic acid?
3-Bromo-2-aminophenylacetic acid is a very important organic compound. When storing and transporting, many key matters need to be paid attention to.
In terms of storage, the first environmental conditions. This compound should be stored in a cool, dry and well-ventilated place. Because it may be sensitive to heat and moisture, if the storage environment temperature is too high or the humidity is too high, it may cause the compound to deteriorate and affect its quality and stability. Therefore, it is advisable to choose a warehouse with moderate temperature and controlled humidity, and the warehouse needs to have good ventilation facilities to disperse volatile gases that may accumulate.
In addition, it is necessary to pay attention to the integrity of the package. Make sure that the package is tightly packed to prevent contact with air, moisture, etc. Commonly used packaging materials such as glass bottles, plastic bottles or sealed metal containers must have good sealing performance. If the package is damaged, the outside air and moisture can easily invade, causing chemical reactions and causing the compound to fail.
During transportation, safety is the top priority. Since 3-bromo-2-aminophenylacetic acid may be dangerous, it is necessary to follow relevant regulations and safety standards when transporting. Vehicles must be equipped with necessary protective and emergency equipment, such as fire extinguishers, leakage emergency treatment tools, etc. And transportation personnel should be professionally trained and familiar with the characteristics of the compound and emergency treatment methods.
In addition, vibration and collision should be prevented. This compound may have an unstable reaction during shaking or collision, so it is necessary to ensure that it is in a stable state during transportation to avoid violent shaking. Care should also be taken during loading and unloading to prevent damage to the packaging.
In short, proper storage and safe transportation are essential to maintain the quality and stability of 3-bromo-2-aminophenylacetic acid, and the relevant specifications and requirements must be strictly followed during operation.
In terms of storage, the first environmental conditions. This compound should be stored in a cool, dry and well-ventilated place. Because it may be sensitive to heat and moisture, if the storage environment temperature is too high or the humidity is too high, it may cause the compound to deteriorate and affect its quality and stability. Therefore, it is advisable to choose a warehouse with moderate temperature and controlled humidity, and the warehouse needs to have good ventilation facilities to disperse volatile gases that may accumulate.
In addition, it is necessary to pay attention to the integrity of the package. Make sure that the package is tightly packed to prevent contact with air, moisture, etc. Commonly used packaging materials such as glass bottles, plastic bottles or sealed metal containers must have good sealing performance. If the package is damaged, the outside air and moisture can easily invade, causing chemical reactions and causing the compound to fail.
During transportation, safety is the top priority. Since 3-bromo-2-aminophenylacetic acid may be dangerous, it is necessary to follow relevant regulations and safety standards when transporting. Vehicles must be equipped with necessary protective and emergency equipment, such as fire extinguishers, leakage emergency treatment tools, etc. And transportation personnel should be professionally trained and familiar with the characteristics of the compound and emergency treatment methods.
In addition, vibration and collision should be prevented. This compound may have an unstable reaction during shaking or collision, so it is necessary to ensure that it is in a stable state during transportation to avoid violent shaking. Care should also be taken during loading and unloading to prevent damage to the packaging.
In short, proper storage and safe transportation are essential to maintain the quality and stability of 3-bromo-2-aminophenylacetic acid, and the relevant specifications and requirements must be strictly followed during operation.
Scan to WhatsApp
