Linshang Chemical
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Benzeneacetonitrile,3-Chloro-4-Fluoro-
Linshang Chemical
|
HS Code |
995457 |
| Chemical Formula | C8H5ClFN |
| Molecular Weight | 169.58 |
| Appearance | Solid (Typical) |
| Solubility In Water | Low solubility (Aromatic nitriles generally have low water solubility) |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform etc. |
| Vapor Pressure | Low (Typical for non - volatile organic solids) |
As an accredited Benzeneacetonitrile,3-Chloro-4-Fluoro- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 3 - chloro - 4 - fluorobenzeneacetonitrile packaged in a sealed plastic bottle. |
| Storage | **Storage of 3 - chloro - 4 - fluorobenzeneacetonitrile** Store 3 - chloro - 4 - fluorobenzeneacetonitrile in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. This chemical should be stored in a tightly sealed container, preferably made of corrosion - resistant materials, to prevent leakage and exposure to air or moisture, which could potentially initiate reactions. |
| Shipping | Benzeneacetonitrile, 3 - chloro - 4 - fluoro - is shipped in accordance with strict chemical transport regulations. Packed in specialized containers to prevent leakage, it is transported by approved carriers, ensuring safety during transit. |
Competitive Benzeneacetonitrile,3-Chloro-4-Fluoro- prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
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What are the physical properties of 3-chloro-4-fluorophenylacetonitrile?
3-Bromo-4-chlorophenylacetic acid is one of the organic compounds. Its physical properties are quite important, and I will describe them in detail for you today.
In terms of its properties, under room temperature, it is mostly white to white crystalline powder, with fine texture and stable morphology, which is easy to store and use. This appearance characteristic is of great significance in many chemical operations and subsequent applications.
When it comes to the melting point, the melting point of 3-bromo-4-chlorophenylacetic acid is in a specific range, between [X] ° C and [X] ° C. The determination of the melting point is a key indicator to identify the purity of this compound and the controlled product. If the melting point deviates from the normal range, or implies that there are impurities mixed in it, it will affect its quality and performance.
As for solubility, it exhibits unique solubility characteristics in organic solvents. It is easily soluble in organic solvents such as dichloromethane, chloroform, and ether. In dichloromethane, it can quickly disperse and dissolve to form a uniform solution. This good solubility facilitates the choice of reaction solvents in organic synthesis, which is conducive to the separation of reactions and products. However, its solubility in water is very small, and this property also determines its application limitations when dealing with the operation of aqueous systems.
Another density, 3-bromo-4-chlorophenylacetic acid has a specific density value, which is about [X] g/cm ³. The physical quantity of density plays an important role in material measurement and storage container design in chemical production. Accurately knowing its density can ensure accurate material ratio in the production process, improve production efficiency and product quality.
In addition, it has certain stability, but under specific conditions, such as high temperature, strong acid and alkali environment, chemical reactions may also occur, causing changes in its structure and properties. Therefore, when storing and using, it is necessary to pay attention to the impact of environmental factors on its stability to ensure its performance is intact.
In terms of its properties, under room temperature, it is mostly white to white crystalline powder, with fine texture and stable morphology, which is easy to store and use. This appearance characteristic is of great significance in many chemical operations and subsequent applications.
When it comes to the melting point, the melting point of 3-bromo-4-chlorophenylacetic acid is in a specific range, between [X] ° C and [X] ° C. The determination of the melting point is a key indicator to identify the purity of this compound and the controlled product. If the melting point deviates from the normal range, or implies that there are impurities mixed in it, it will affect its quality and performance.
As for solubility, it exhibits unique solubility characteristics in organic solvents. It is easily soluble in organic solvents such as dichloromethane, chloroform, and ether. In dichloromethane, it can quickly disperse and dissolve to form a uniform solution. This good solubility facilitates the choice of reaction solvents in organic synthesis, which is conducive to the separation of reactions and products. However, its solubility in water is very small, and this property also determines its application limitations when dealing with the operation of aqueous systems.
Another density, 3-bromo-4-chlorophenylacetic acid has a specific density value, which is about [X] g/cm ³. The physical quantity of density plays an important role in material measurement and storage container design in chemical production. Accurately knowing its density can ensure accurate material ratio in the production process, improve production efficiency and product quality.
In addition, it has certain stability, but under specific conditions, such as high temperature, strong acid and alkali environment, chemical reactions may also occur, causing changes in its structure and properties. Therefore, when storing and using, it is necessary to pay attention to the impact of environmental factors on its stability to ensure its performance is intact.
What are the chemical properties of 3-chloro-4-fluorophenylacetonitrile?
Ethyl 3-bromo-4-chlorobenzoate is an organic compound with unique chemical properties.
It has ester properties and can undergo hydrolysis. Under acidic conditions, hydrolysis generates 3-bromo-4-chlorobenzoic acid and ethanol. In the words "acid catalysis, water meets ester, ester bond breaks, acid and alcohol regenerate", this reaction is gradual and follows the rules of chemistry.
Under alkaline conditions, hydrolysis is more complete, resulting in 3-bromo-4-chlorobenzoate and ethanol. The base is like a helping hand, pushing the reaction to the right, because the base reacts with the formed acid, causing the equilibrium to shift.
Furthermore, the compound contains halogen atoms bromine and chlorine, which can participate in nucleophilic substitution reactions. The activity of halogen atoms is different, and chlorine is more active than bromine. When encountering nucleophilic reagents, halogen atoms can be replaced. If the nucleophilic reagent enters the opportunity, it replaces the position of the halogen atom to form a new compound.
It can also participate in the reduction reaction, and the carbonyl group in the molecule can be reduced. With a suitable reducing agent, the carbonyl group is converted into an alcoholic hydroxyl group, which changes the structure and properties of the compound.
In addition, due to the presence of benzene rings, ethyl 3-bromo-4-chlorobenzoate can undergo aromatic electrophilic substitution reactions. The benzene ring is rich in electrons During the reaction, electrophilic reagents attack the benzene ring and replace the hydrogen atoms on it to form new aromatic compounds.
The chemical properties of this compound are diverse and it is widely used in the field of organic synthesis. Different products can be prepared through various reactions, providing many possibilities for organic chemistry research and practical production.
It has ester properties and can undergo hydrolysis. Under acidic conditions, hydrolysis generates 3-bromo-4-chlorobenzoic acid and ethanol. In the words "acid catalysis, water meets ester, ester bond breaks, acid and alcohol regenerate", this reaction is gradual and follows the rules of chemistry.
Under alkaline conditions, hydrolysis is more complete, resulting in 3-bromo-4-chlorobenzoate and ethanol. The base is like a helping hand, pushing the reaction to the right, because the base reacts with the formed acid, causing the equilibrium to shift.
Furthermore, the compound contains halogen atoms bromine and chlorine, which can participate in nucleophilic substitution reactions. The activity of halogen atoms is different, and chlorine is more active than bromine. When encountering nucleophilic reagents, halogen atoms can be replaced. If the nucleophilic reagent enters the opportunity, it replaces the position of the halogen atom to form a new compound.
It can also participate in the reduction reaction, and the carbonyl group in the molecule can be reduced. With a suitable reducing agent, the carbonyl group is converted into an alcoholic hydroxyl group, which changes the structure and properties of the compound.
In addition, due to the presence of benzene rings, ethyl 3-bromo-4-chlorobenzoate can undergo aromatic electrophilic substitution reactions. The benzene ring is rich in electrons During the reaction, electrophilic reagents attack the benzene ring and replace the hydrogen atoms on it to form new aromatic compounds.
The chemical properties of this compound are diverse and it is widely used in the field of organic synthesis. Different products can be prepared through various reactions, providing many possibilities for organic chemistry research and practical production.
What are the main uses of 3-chloro-4-fluorophenylacetonitrile?
3-Deuterium-4-tritium acetamide is widely used. In the field of medicine, it is an important raw material for the preparation of special drugs. Due to the special nuclear properties of deuterium and tritium, the drugs prepared based on it may have specific performance in metabolism and pharmacological activity in the body, which can help doctors develop new drugs with better curative effect and less side effects.
In the process of scientific research, 3-deuterium-4-tritium acetamide is also a key tracer. With its radioactive tritium, it can be accurately traced in chemical reactions and biological processes, helping researchers to clarify the reaction mechanism, material transport and metabolic pathway. If the uptake and transformation process of specific substances by cells is studied, the introduction of this tracer can be used to detect the radioactivity of tritium and gain insight into the whole process.
Furthermore, in the field of materials science, it also has its own impact. It can be used to prepare materials with special properties, and use the characteristics of deuterium and tritium to improve the structure and properties of materials, such as the development of special adsorption materials, catalytic materials, etc., to improve the adsorption efficiency and catalytic activity of materials, and play an important role in chemical production and environmental protection.
And in nuclear energy-related research, 3-deuterium-4-tritium acetamide may be indirectly related. Due to the fact that deuterium and tritium are important fuels for nuclear fusion, the research on compounds containing these two may provide relevant data and theoretical support for nuclear fusion research, and assist in the exploration of nuclear energy development and utilization.
In the process of scientific research, 3-deuterium-4-tritium acetamide is also a key tracer. With its radioactive tritium, it can be accurately traced in chemical reactions and biological processes, helping researchers to clarify the reaction mechanism, material transport and metabolic pathway. If the uptake and transformation process of specific substances by cells is studied, the introduction of this tracer can be used to detect the radioactivity of tritium and gain insight into the whole process.
Furthermore, in the field of materials science, it also has its own impact. It can be used to prepare materials with special properties, and use the characteristics of deuterium and tritium to improve the structure and properties of materials, such as the development of special adsorption materials, catalytic materials, etc., to improve the adsorption efficiency and catalytic activity of materials, and play an important role in chemical production and environmental protection.
And in nuclear energy-related research, 3-deuterium-4-tritium acetamide may be indirectly related. Due to the fact that deuterium and tritium are important fuels for nuclear fusion, the research on compounds containing these two may provide relevant data and theoretical support for nuclear fusion research, and assist in the exploration of nuclear energy development and utilization.
What is the preparation method of 3-chloro-4-fluorophenylacetonitrile?
The preparation method of 3-bromo-4-ethoxyacetaniline is obtained by chemical synthesis. The method is as follows:
First take an appropriate amount of p-aminophenyl ether and place it in a clean reaction vessel. The p-aminophenyl ether has a specific chemical structure and is the starting material for the reaction. Then, the brominating agent is added dropwise to this reaction vessel at a suitable rate. The choice of brominating agent needs to meet the requirements of the reaction, and the rate of dropwise addition is also related to the process and effect of the reaction. This step of the reaction aims to replace the hydrogen atom at a specific position in the p-aminophenyl ether molecule with a bromine atom to produce an intermediate product.
During the reaction, precise temperature control is required to ensure that the reaction is carried out within a suitable temperature range. If the temperature is too high or too low, it can cause abnormal reaction rates or generate unnecessary by-products. The method of temperature control is often achieved by water bath, oil bath or other temperature control devices.
After the bromination reaction is completed, appropriate separation and purification techniques are used to remove impurities in the reaction system. The separation method can be extracted, filtered, distilled and other means. The extractor separates the target product from impurities by the different solubility of the solute in different solvents; filtration removes insoluble solid impurities; distillation can achieve separation according to the different boiling points of each component.
After purification, react with acetylating reagents. The addition of acetylating reagents should also pay attention to the dosage and reaction conditions. The purpose of this reaction is to combine the intermediate product with the acetylating reagent to obtain 3-bromo-4-ethoxyacetaniline.
After the reaction is completed, it is repeated through refining steps, such as recrystallization, to improve the purity of the product. In the case of recrystallization, the product is crystallized and precipitated by the change of solubility of the substance at different temperatures, and the product is left in the mother liquor to obtain high-purity 3-bromo-4-ethoxyacetaniline. In this way, according to this series of steps, the desired 3-bromo-4-ethoxyacetaniline can be obtained.
First take an appropriate amount of p-aminophenyl ether and place it in a clean reaction vessel. The p-aminophenyl ether has a specific chemical structure and is the starting material for the reaction. Then, the brominating agent is added dropwise to this reaction vessel at a suitable rate. The choice of brominating agent needs to meet the requirements of the reaction, and the rate of dropwise addition is also related to the process and effect of the reaction. This step of the reaction aims to replace the hydrogen atom at a specific position in the p-aminophenyl ether molecule with a bromine atom to produce an intermediate product.
During the reaction, precise temperature control is required to ensure that the reaction is carried out within a suitable temperature range. If the temperature is too high or too low, it can cause abnormal reaction rates or generate unnecessary by-products. The method of temperature control is often achieved by water bath, oil bath or other temperature control devices.
After the bromination reaction is completed, appropriate separation and purification techniques are used to remove impurities in the reaction system. The separation method can be extracted, filtered, distilled and other means. The extractor separates the target product from impurities by the different solubility of the solute in different solvents; filtration removes insoluble solid impurities; distillation can achieve separation according to the different boiling points of each component.
After purification, react with acetylating reagents. The addition of acetylating reagents should also pay attention to the dosage and reaction conditions. The purpose of this reaction is to combine the intermediate product with the acetylating reagent to obtain 3-bromo-4-ethoxyacetaniline.
After the reaction is completed, it is repeated through refining steps, such as recrystallization, to improve the purity of the product. In the case of recrystallization, the product is crystallized and precipitated by the change of solubility of the substance at different temperatures, and the product is left in the mother liquor to obtain high-purity 3-bromo-4-ethoxyacetaniline. In this way, according to this series of steps, the desired 3-bromo-4-ethoxyacetaniline can be obtained.
What are the precautions for using 3-chloro-4-fluorophenylacetonitrile?
3-Chloro-4-fluorophenylacetamide is an organic compound. During use, many precautions should not be taken lightly.
First, safety protection must be comprehensive. This compound may be toxic and irritating, and appropriate protective equipment must be worn during operation, such as gloves, protective glasses and laboratory clothes, to prevent skin contact and eye splashing. If inadvertently exposed, rinse with plenty of water immediately and seek medical treatment according to specific conditions.
Second, storage conditions must be appropriate. Store in a cool, dry and well-ventilated place, away from fire and heat sources. At the same time, store separately from oxidants, acids, alkalis, etc., and do not mix to avoid dangerous chemical reactions.
Third, the use environment needs to be carefully controlled. The operation should be carried out in the fume hood to ensure good ventilation and prevent the diffusion of steam or dust in the air and inhalation by the human body.
Fourth, strictly follow the operating procedures. Before use, be sure to know its chemical properties and reaction characteristics. Weighing, dissolving and other operations must be accurate, and the dosage and reaction conditions should be strictly controlled according to experimental or production requirements.
Fifth, waste disposal should not be sloppy. After use, the remaining 3-chloro-4-fluorophenylacetamide and related waste must not be discarded at will. It should be properly disposed of in accordance with relevant regulations to prevent pollution to the environment. Only when using 3-chloro-4-fluorophenylacetamide can we ensure safe operation, avoid accidents, and effectively protect the environment and human health.
First, safety protection must be comprehensive. This compound may be toxic and irritating, and appropriate protective equipment must be worn during operation, such as gloves, protective glasses and laboratory clothes, to prevent skin contact and eye splashing. If inadvertently exposed, rinse with plenty of water immediately and seek medical treatment according to specific conditions.
Second, storage conditions must be appropriate. Store in a cool, dry and well-ventilated place, away from fire and heat sources. At the same time, store separately from oxidants, acids, alkalis, etc., and do not mix to avoid dangerous chemical reactions.
Third, the use environment needs to be carefully controlled. The operation should be carried out in the fume hood to ensure good ventilation and prevent the diffusion of steam or dust in the air and inhalation by the human body.
Fourth, strictly follow the operating procedures. Before use, be sure to know its chemical properties and reaction characteristics. Weighing, dissolving and other operations must be accurate, and the dosage and reaction conditions should be strictly controlled according to experimental or production requirements.
Fifth, waste disposal should not be sloppy. After use, the remaining 3-chloro-4-fluorophenylacetamide and related waste must not be discarded at will. It should be properly disposed of in accordance with relevant regulations to prevent pollution to the environment. Only when using 3-chloro-4-fluorophenylacetamide can we ensure safe operation, avoid accidents, and effectively protect the environment and human health.
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