Benzeneacetonitrile, 4-Chloro-3-Fluoro-

Linshang Chemical

Specifications

HS Code

994524

Chemical Formula C8H5ClFN
Molecular Weight 171.58
Appearance Typically a solid
Physical State At Room Temperature Solid
Melting Point Data may vary by source
Boiling Point Data may vary by source
Density Data may vary by source
Solubility In Water Low solubility
Solubility In Organic Solvents Soluble in common organic solvents
Odor No specific common odor description
Purity In Commercial Form Varies by grade

As an accredited Benzeneacetonitrile, 4-Chloro-3-Fluoro- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 4 - chloro - 3 - fluoro - benzeneacetonitrile in a sealed, labeled chemical - grade bottle.
Storage Store "4 - chloro - 3 - fluoro - benzeneacetonitrile" in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly sealed container to prevent leakage and exposure to air or moisture, which could potentially lead to decomposition or unwanted reactions. Label containers clearly for easy identification and safety.
Shipping 4 - chloro - 3 - fluorobenzeneacetonitrile is shipped in accordance with strict chemical regulations. Packed in appropriate containers, it's transported by specialized carriers ensuring safety during transit to prevent any environmental or safety hazards.
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Benzeneacetonitrile, 4-Chloro-3-Fluoro- Benzeneacetonitrile, 4-Chloro-3-Fluoro-
General Information
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Frequently Asked Questions

As a leading Benzeneacetonitrile, 4-Chloro-3-Fluoro- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 4-chloro-3-fluorophenylacetonitrile?
The chemical properties of 4-cyanogen-3-fluorobenzyl acetate are quite unique. Among this compound, the cyano group (-CN), the fluorine atom (-F) and the benzyl acetate structure coexist and interact with each other, resulting in its unique properties.
The presence of cyanyl gives the compound a certain reactivity. Cyanyl groups can participate in many chemical reactions, such as hydrolysis reactions. Under specific conditions, cyanyl groups can be gradually converted into carboxyl groups (-COOH), which can be carried out in acidic or alkaline environments. Under alkaline conditions, hydrolysis of cyanyl groups is more common, first forming amide intermediates, and then further hydrolyzing into carboxylic acids. The introduction of
fluorine atoms significantly affects the electron cloud distribution and spatial structure of molecules. Fluorine atoms have strong electronegativity, which can enhance the polarity of molecules and affect their physical properties, such as boiling point, melting point and solubility. At the same time, in chemical reactions, due to the influence of fluorine atoms on the electronic effect of ortho-groups, the activity of the check point of the reaction will be changed, guiding the reaction in a specific direction. For example, in nucleophilic substitution reactions, the substitution reaction activity on the ortho-carbon of the fluorine atom may be changed due to the electron-absorbing effect of the fluorine atom.
The benzyl acetate part adds a certain degree of hydrophobicity to the molecule. The aromatic nature of benzyl structure makes it stable to a certain extent, while the acetate group (-COOCH -2 CH
) can undergo the typical reactions of esters, such as hydrolysis, alcoholysis and aminolysis. In the hydrolysis reaction, under the catalysis of acid or base, the ester bond is broken to form the corresponding carboxylic acid and alcohol.
In summary, 4-cyanogen-3-fluorobenzyl acetate exhibits rich and unique chemical properties due to the interaction of various parts of the structure. It can be used as an important intermediate in the field of organic synthesis and participates in the construction of various complex organic compounds.
What are the main uses of 4-chloro-3-fluorophenylacetonitrile?
4-Tritium-3-deuteroethyl ether, although not detailed in "Tiangong Kaiwu", has a wide range of uses in today's world.
In the chemical industry, it can be used as an organic solvent. Because of its unique solubility, it can effectively dissolve many organic compounds, so in the preparation process of coatings, inks and adhesives, it is often used to dissolve resins, pigments and other ingredients to help them disperse uniformly, thereby improving the quality and performance of products. For example, when preparing high-end automotive paints, 4-tritium-3-deuteroethyl ether can make the paint adhere more evenly to the car body, resulting in a brighter and longer-lasting color.
In the synthesis of medicine, it also has important uses. It is often used as a reaction intermediate and participates in the construction of many drug molecules. Due to its special chemical structure, it can guide the reaction in a specific direction, which is helpful for the synthesis of drug components with specific activities. Taking the synthesis of some cardiovascular diseases as an example, 4-tritium-3-deuteroethyl ether can precisely connect different chemical groups in key reaction steps to help synthesize target drug molecules.
In the field of scientific research, because it contains special tritium and deuterium atoms, it can be used as a tracer. Researchers can further explore the reaction mechanism or material metabolism pathway by tracking its traces in chemical reactions or organisms. For example, in the process of studying the absorption and transformation of specific organic substances by plants, markers containing 4-tritium-3-deuterium ethyl ether are applied to plants, and the dynamic changes of the substances in plants can be clarified by detecting the radioactivity or other properties of tritium and deuterium.
What is the production method of 4-chloro-3-fluorophenylacetonitrile?
4-Deuterium-3-tritium ethyl isopropyl ether is an extraordinary drug, and its preparation method is very delicate.
To make this drug, you first need to prepare the required materials, such as special raw materials containing deuterium and tritium, and isopropyl ether-related reagents suitable for the reaction. The purity of the raw materials is related to the quality of the drug, and there must be no slack.
The preparation process is multi-step chemical synthesis. Or first, atoms containing deuterium and tritium are introduced into a suitable organic molecular structure according to a specific chemical reaction. This step requires precise control of the reaction conditions, such as temperature, pressure, and reaction time, all of which need to be just right. If the temperature is too high, the reaction will be overheated, or the product will be impure; if the temperature is too low, the reaction will be delayed or even stagnant.
When the basic structure containing deuterium and tritium is first formed, and then chemically coupled with the related precursors of isopropyl ether according to the established reaction path, a specific catalyst may be required to help the reaction proceed smoothly. The amount of catalyst also needs to be accurately weighed. Too much or too little will have a significant impact on the efficiency of the reaction, the quantity and quality of the product.
After the reaction is completed, the product may be mixed with impurities, so it needs to be carefully separated and purified. Or use the method of distillation to separate the product from the impurities according to the difference in the boiling point of different substances; or use the method of chromatography to borrow the difference in the distribution coefficient of the substance between the stationary phase and the mobile phase to achieve the purpose of purification. After layer-by-layer processes, remove the voids and store the cyanine to obtain pure 4-deuterium-3-tritium ethyl isopropyl ether.
The whole preparation method requires rigorous operation at every step, and if there is a slight mistake, all previous efforts will be in vain. Those who need to make medicines can achieve this rare medicine only with awe and intensive research skills.
What are the precautions for 4-chloro-3-fluorophenylacetonitrile in storage and transportation?
4-Deuterium-3-tritium ethyl ethanol is a special chemical substance. When storing and transporting, many matters must be paid attention to.
First, because of its special chemical properties, it must be placed in a cool and ventilated warehouse. This is because the temperature is too high or the ventilation is not smooth, which is easy to cause chemical reactions and cause danger. Second, the temperature and humidity of the warehouse must be strictly controlled. The temperature should be maintained within a specific range to prevent the properties of the substance from changing; the humidity should not be too high, otherwise the substance may be deteriorated by moisture. Third, the substance should be stored separately from oxidants, acids, etc., and must not be mixed. Because of contact with it, it is easy to trigger violent chemical reactions and endanger safety. Fourth, the storage place must be equipped with suitable materials to contain leaks, in case of accidental leakage, it can be disposed of in a timely and effective manner to reduce the harm.
As for transportation, first, make sure that the packaging is complete and the loading is safe before transportation. If the packaging is damaged, it may cause material leakage during transportation. Second, during transportation, the relevant transportation regulations and routes should be strictly adhered to, and cannot be changed at will. Third, the transportation vehicle must be equipped with the corresponding variety and quantity of fire fighting equipment and leakage emergency treatment equipment. This is to deal with emergencies, and in the event of leaks or fires, rescue can be launched quickly. Fourth, transportation personnel must also undergo professional training, be familiar with the characteristics of the substance and emergency treatment methods, drive cautiously during transportation, avoid sudden braking, sharp turns, etc., to prevent material leakage due to damaged packaging.
What are the effects of 4-chloro-3-fluorophenylacetonitrile on the environment and human health?
4-Bromo-3-chlorophenylacetic acid, the impact of this substance on the environment and human health needs to be investigated in detail.
At the environmental end, there may be several potential effects. If this substance is released in nature, or through industrial emissions, improper disposal, etc., it enters water bodies, soils and atmospheres. In soil, it may disturb the structure and function of soil microbial communities. Soil microorganisms are crucial to maintaining soil fertility and decomposing organic matter. Once the community is disturbed, it may cause soil ecological imbalance and affect plant growth. In water bodies, 4-bromo-3-chlorophenylacetic acid may pose a hazard to aquatic organisms. Such as some fish, shellfish, etc., are sensitive to such substances, or cause abnormal physiological functions, and even die, thereby destroying the balance of aquatic ecosystems. And it has a certain persistence in the environment, is difficult to degrade rapidly, or accumulates in the environment, causing the scope of pollution to become wider and deeper.
As for human health, there is also a potential threat. 4-Bromo-3-chlorophenylacetic acid may enter the human body through oral, respiratory or skin contact. After entering the body, it may interfere with the normal physiological and biochemical processes of the human body. Its chemical structure may make it toxic and cause damage to human cells. For example, it may affect the metabolic function of cells, block cell energy generation, and cause fatigue, weakness, etc. It may also have a negative effect on the human immune system, weakening the human body's ability to resist pathogens, making the human body more susceptible to disease. And studies have shown that some halogenated aromatic hydrocarbons are potentially carcinogenic, and the chemical properties of 4-bromo-3-chlorophenylacetic acid are similar. Although it has not been confirmed that it causes cancer, the latent risk cannot be ignored.
In summary, 4-bromo-3-chlorophenylacetic acid has potential adverse effects on the environment and human health. It needs to be treated strictly, and control and research should be strengthened to clarify its exact harm, find effective countermeasures, and protect the environment and human safety.