Linshang Chemical
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Benzeneacetonitrile, 4-Chloro-3-(Trifluoromethyl)-
Linshang Chemical
|
HS Code |
790728 |
| Chemical Formula | C9H5ClF3N |
| Molecular Weight | 221.59 |
| Appearance | Solid (usually) |
| Melting Point | Data may vary, needs experimental determination |
| Boiling Point | Data may vary, needs experimental determination |
| Solubility In Water | Low solubility in water |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, toluene |
| Density | Data may vary, needs experimental determination |
| Vapor Pressure | Low vapor pressure |
| Flash Point | Data may vary, needs experimental determination |
As an accredited Benzeneacetonitrile, 4-Chloro-3-(Trifluoromethyl)- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 4 - chloro - 3 - (trifluoromethyl)benzeneacetonitrile in sealed chemical - grade container. |
| Storage | Store “4 - chloro - 3 - (trifluoromethyl)benzeneacetonitrile” in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly - sealed container made of corrosion - resistant material to prevent leakage and exposure to air and moisture, which could potentially cause degradation. |
| Shipping | Ship "4 - chloro - 3 - (trifluoromethyl)benzeneacetonitrile" in tightly - sealed, corrosion - resistant containers. Follow all hazardous chemical shipping regulations, ensuring proper labeling for safe and compliant transportation. |
Competitive Benzeneacetonitrile, 4-Chloro-3-(Trifluoromethyl)- prices that fit your budget—flexible terms and customized quotes for every order.
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What are the physical properties of 4-chloro-3- (trifluoromethyl) phenylacetonitrile?
4-Deuterium-3- (trideuteromethyl) phenylethanol is an organic compound. Its physical properties are quite important, and it is related to many characteristics and applications of this compound.
First of all, its properties, under room temperature and pressure, are mostly colorless to light yellow liquid, the appearance is clear and transparent, and no obvious impurities are visible. This is its intuitive physical manifestation, which is easy to observe and distinguish.
When it comes to the melting point, the melting point of this compound is in a specific range. However, due to the presence of deuterium atoms, the intermolecular force is different from that of ordinary phenylethanol, so its melting point may be different from that of ordinary congeners. This melting point property is of critical significance in the purification and crystallization process of substances. It can help to determine the purity of substances and is also an important parameter for controlling the production process.
The boiling point is also an important physical property. Due to the special substituents in the structure, the intermolecular forces are changed, and the boiling point is different from that of common phenylethanol. A higher boiling point means that more energy is required to vaporize it, which has a great impact on chemical operations such as distillation and separation, and is related to the efficiency of product separation and purification.
Density is one of the important properties of substances. The density of 4-deuterium-3- (trideuteromethyl) phenylethanol is different from that of water and common organic solvents. This property has important applications in liquid-liquid extraction, stratification and other operations. It can achieve effective separation of substances
In terms of solubility, it has good solubility in some organic solvents, such as ethanol and ether. Due to the similarity of molecular structure with organic solvents, it follows the principle of similar miscibility. However, the solubility in water is relatively poor. This difference provides convenience for its separation, purification and practical application. Suitable solvents can be selected to achieve specific purposes.
In addition, the refractive index of this compound also has unique characteristics. The refractive index reflects the ability of the substance to refract light. Different concentrations and purity samples have different refractive indices. Therefore, it can be used to measure the refractive index to monitor the purity and concentration changes of the substance, which is of great significance in quality control. The unique physical properties of 4-deuterium-3- (trideuteromethyl) phenylethanol are a key consideration in many fields such as chemical synthesis, drug development, analysis and testing, which help scientists and engineers to effectively control substances and achieve desired goals.
First of all, its properties, under room temperature and pressure, are mostly colorless to light yellow liquid, the appearance is clear and transparent, and no obvious impurities are visible. This is its intuitive physical manifestation, which is easy to observe and distinguish.
When it comes to the melting point, the melting point of this compound is in a specific range. However, due to the presence of deuterium atoms, the intermolecular force is different from that of ordinary phenylethanol, so its melting point may be different from that of ordinary congeners. This melting point property is of critical significance in the purification and crystallization process of substances. It can help to determine the purity of substances and is also an important parameter for controlling the production process.
The boiling point is also an important physical property. Due to the special substituents in the structure, the intermolecular forces are changed, and the boiling point is different from that of common phenylethanol. A higher boiling point means that more energy is required to vaporize it, which has a great impact on chemical operations such as distillation and separation, and is related to the efficiency of product separation and purification.
Density is one of the important properties of substances. The density of 4-deuterium-3- (trideuteromethyl) phenylethanol is different from that of water and common organic solvents. This property has important applications in liquid-liquid extraction, stratification and other operations. It can achieve effective separation of substances
In terms of solubility, it has good solubility in some organic solvents, such as ethanol and ether. Due to the similarity of molecular structure with organic solvents, it follows the principle of similar miscibility. However, the solubility in water is relatively poor. This difference provides convenience for its separation, purification and practical application. Suitable solvents can be selected to achieve specific purposes.
In addition, the refractive index of this compound also has unique characteristics. The refractive index reflects the ability of the substance to refract light. Different concentrations and purity samples have different refractive indices. Therefore, it can be used to measure the refractive index to monitor the purity and concentration changes of the substance, which is of great significance in quality control. The unique physical properties of 4-deuterium-3- (trideuteromethyl) phenylethanol are a key consideration in many fields such as chemical synthesis, drug development, analysis and testing, which help scientists and engineers to effectively control substances and achieve desired goals.
What are the chemical properties of 4-chloro-3- (trifluoromethyl) phenylacetonitrile
The chemical properties of 4-tritium-3- (triethylmethyl) phenylisopropionic acid are particularly complex. This compound contains tritium, tritium, and the radioactive isotope of hydrogen is also radioactive, and it can spontaneously decay and release beta particles. This is its remarkable chemical property. Its decay can cause changes in the molecular structure, affecting its chemical activity and reaction path.
Furthermore, the structure of triethylmethyl and phenylisopropionic acid in the molecule also has its unique chemical properties. Triethylmethyl has a certain steric hindrance effect, which can affect the spatial configuration and reactivity of molecules. In chemical reactions, due to its steric hindrance, the reaction of neighboring groups may be hindered, or the reaction may be selectively changed.
The benzene isopropionic acid part, the benzene ring is aromatic and has high stability, and is prone to electrophilic substitution reactions, such as halogenation, nitration, sulfonation, etc. The carboxyl group (-COOH) is acidic and can be neutralized with the base to form the corresponding salt. And the carboxyl group can participate in the esterification reaction and form an ester with alcohols under acid catalysis.
At the same time, the interaction between the groups in this compound cannot be ignored. The conjugation effect between the benzene ring and the carboxyl group may affect the electron cloud density distribution of the benzene ring, thereby changing the activity and check point of the electrophilic substitution reaction. The interaction of the electronic effect and the space effect between the triethyl group and the benzene ring and the carboxyl group makes the chemical properties of this compound more abundant and variable. It may have unique application and research value in the fields of organic synthesis, medicinal chemistry, etc. However, due to the radioactivity of tritium, safety factors need to be carefully considered during use and research.
Furthermore, the structure of triethylmethyl and phenylisopropionic acid in the molecule also has its unique chemical properties. Triethylmethyl has a certain steric hindrance effect, which can affect the spatial configuration and reactivity of molecules. In chemical reactions, due to its steric hindrance, the reaction of neighboring groups may be hindered, or the reaction may be selectively changed.
The benzene isopropionic acid part, the benzene ring is aromatic and has high stability, and is prone to electrophilic substitution reactions, such as halogenation, nitration, sulfonation, etc. The carboxyl group (-COOH) is acidic and can be neutralized with the base to form the corresponding salt. And the carboxyl group can participate in the esterification reaction and form an ester with alcohols under acid catalysis.
At the same time, the interaction between the groups in this compound cannot be ignored. The conjugation effect between the benzene ring and the carboxyl group may affect the electron cloud density distribution of the benzene ring, thereby changing the activity and check point of the electrophilic substitution reaction. The interaction of the electronic effect and the space effect between the triethyl group and the benzene ring and the carboxyl group makes the chemical properties of this compound more abundant and variable. It may have unique application and research value in the fields of organic synthesis, medicinal chemistry, etc. However, due to the radioactivity of tritium, safety factors need to be carefully considered during use and research.
What are the main uses of 4-chloro-3- (trifluoromethyl) phenylacetonitrile?
4--3- (triethylmethyl) quinoxaline, a special chemical compound, has profound uses.
In the field of research, this compound plays an important role. Because of its specific chemical activity, it can be used in front of the material. Or it can be modified by subtle chemical modification to target specific biomolecules, such as proteins, enzymes, etc. For example, in the research of certain diseases, such as tumors and inflammation, 4--3- (triethylmethyl) quinoxaline can be used to control its function and cure its efficacy by reasonable combination of pathogenic proteins.
In the field of materials, this compound also exhibits multiple forces. Due to its unique properties, it may be useful for the synthesis of polymeric materials. In polymerization, 4-3- (triethylmethyl) quinoxaline can be filled with functional properties, and its special properties can be introduced into the polymer. In this way, the synthesized polymer materials may have special optical, optical, or mechanical properties, and can be used in high-performance optical materials, polymers, etc., and can be widely used in the fields of optical devices, general technologies, etc.
Furthermore, in the synthesis of chemicals, 4-3- (triethylmethyl) quinoxaline can be used as an important component. With its basis, many compounds with different functions can be derived from a series of reactions. It can provide rich starting materials for synthesizers, expand the diversity of synthetic pathways, and assist in the synthesis of more useful molecules with specific applications.
In the field of research, this compound plays an important role. Because of its specific chemical activity, it can be used in front of the material. Or it can be modified by subtle chemical modification to target specific biomolecules, such as proteins, enzymes, etc. For example, in the research of certain diseases, such as tumors and inflammation, 4--3- (triethylmethyl) quinoxaline can be used to control its function and cure its efficacy by reasonable combination of pathogenic proteins.
In the field of materials, this compound also exhibits multiple forces. Due to its unique properties, it may be useful for the synthesis of polymeric materials. In polymerization, 4-3- (triethylmethyl) quinoxaline can be filled with functional properties, and its special properties can be introduced into the polymer. In this way, the synthesized polymer materials may have special optical, optical, or mechanical properties, and can be used in high-performance optical materials, polymers, etc., and can be widely used in the fields of optical devices, general technologies, etc.
Furthermore, in the synthesis of chemicals, 4-3- (triethylmethyl) quinoxaline can be used as an important component. With its basis, many compounds with different functions can be derived from a series of reactions. It can provide rich starting materials for synthesizers, expand the diversity of synthetic pathways, and assist in the synthesis of more useful molecules with specific applications.
What are the synthesis methods of 4-chloro-3- (trifluoromethyl) phenylacetonitrile?
To prepare 4-deuterium-3- (trifluoromethyl) phenyl ethanol, the following ancient methods can be used.
First, start with deuterium-containing reagents. Find suitable deuterium-containing raw materials, such as deuterated halogenated hydrocarbons or deuterated alcohols. If deuterated halogenated hydrocarbons are used as the starting point, they can be reacted with aromatic hydrocarbons containing trifluoromethyl under suitable catalysts and conditions. Often catalyzed by transition metal catalysts, such as palladium, nickel, etc. The two are coupled to form aromatic intermediates containing trifluoromethyl and deuterium atoms first. If palladium catalysis is used, in the presence of a base, in a suitable organic solvent, temperature control makes the reaction proceed smoothly, and deuterium atoms and trifluoromethyl atoms at specific positions can be introduced into the aromatic ring.
Then, the resulting intermediate is reduced to form an alcohol. Reduction reagents such as lithium aluminum hydride and sodium borohydride can be selected. If sodium borohydride is used, it is relatively mild. In an alcohol solvent, the carbonyl group of the intermediate or a suitable functional group can be reduced to a hydroxyl group to obtain 4-deuterium-3- (trifluoromethyl) phenylethanol. During operation, pay attention to temperature control and monitoring of the reaction process to prevent excessive reduction or side reactions.
Second, start with aromatic derivatives. First take the aromatic hydrocarbon derivative containing trifluoromethyl and deuterate it. Deuterated acids or deuterated reagents can be used to selectively introduce deuterium atoms into specific positions in the aromatic ring under suitable conditions. For example, with a specific deuterated reagent, under the catalysis of Lewis acid, at low temperature or room temperature, the aromatic ring undergoes electrophilic substitution, and the deuterium atom is introduced into the target position.
Subsequently, the resulting aromatic hydrocarbon containing deuterium and trifluoromethyl is functionally converted. Hydroxyethyl is introduced into the aromatic ring by a suitable reaction, such as with ethylene oxide or halogenated ethanol analogs. This step requires selecting a suitable base, catalyst and solvent according to the selected reaction path to promote the reaction to produce the target product, and finally obtain 4-deuterium-3- (trifluoromethyl) phenylethanol. The whole process requires fine control of the reaction conditions at each step to ensure the purity and yield of the product.
First, start with deuterium-containing reagents. Find suitable deuterium-containing raw materials, such as deuterated halogenated hydrocarbons or deuterated alcohols. If deuterated halogenated hydrocarbons are used as the starting point, they can be reacted with aromatic hydrocarbons containing trifluoromethyl under suitable catalysts and conditions. Often catalyzed by transition metal catalysts, such as palladium, nickel, etc. The two are coupled to form aromatic intermediates containing trifluoromethyl and deuterium atoms first. If palladium catalysis is used, in the presence of a base, in a suitable organic solvent, temperature control makes the reaction proceed smoothly, and deuterium atoms and trifluoromethyl atoms at specific positions can be introduced into the aromatic ring.
Then, the resulting intermediate is reduced to form an alcohol. Reduction reagents such as lithium aluminum hydride and sodium borohydride can be selected. If sodium borohydride is used, it is relatively mild. In an alcohol solvent, the carbonyl group of the intermediate or a suitable functional group can be reduced to a hydroxyl group to obtain 4-deuterium-3- (trifluoromethyl) phenylethanol. During operation, pay attention to temperature control and monitoring of the reaction process to prevent excessive reduction or side reactions.
Second, start with aromatic derivatives. First take the aromatic hydrocarbon derivative containing trifluoromethyl and deuterate it. Deuterated acids or deuterated reagents can be used to selectively introduce deuterium atoms into specific positions in the aromatic ring under suitable conditions. For example, with a specific deuterated reagent, under the catalysis of Lewis acid, at low temperature or room temperature, the aromatic ring undergoes electrophilic substitution, and the deuterium atom is introduced into the target position.
Subsequently, the resulting aromatic hydrocarbon containing deuterium and trifluoromethyl is functionally converted. Hydroxyethyl is introduced into the aromatic ring by a suitable reaction, such as with ethylene oxide or halogenated ethanol analogs. This step requires selecting a suitable base, catalyst and solvent according to the selected reaction path to promote the reaction to produce the target product, and finally obtain 4-deuterium-3- (trifluoromethyl) phenylethanol. The whole process requires fine control of the reaction conditions at each step to ensure the purity and yield of the product.
What are the precautions for 4-chloro-3- (trifluoromethyl) phenylacetonitrile in storage and transportation?
For 4-alkane-3- (triethylmethyl) phenyl isopropanol, it is necessary to be careful whether it is stored or lost.
When hiding, the first environment is heavy. It must be placed in a cool, dry and well ventilated place. This medicine is easy to decompose when heated. If it is placed in a high temperature, the efficacy of the medicine will quickly lose and it will be unusable. It is also afraid of moisture, and moisture will easily cause it to deliquescence and damage its quality. Therefore, it is necessary to hide in a dry place to preserve its quality.
Furthermore, it is also necessary to avoid light. Light can promote its chemical reaction, and the ingredients that cause the medicine will become easy, and the efficacy of the medicine will be damaged. When hiding with dark-colored utensils, or in a dark room, avoid the harm of light.
When losing, protection should not be ignored. The operator must wear appropriate protective equipment, such as gloves, masks, goggles, etc. This medicine may be irritating, and it can cause injury when it touches the skin, enters the mouth and nose. If you accidentally touch it, rinse it with plenty of water quickly, and seek medical attention if necessary.
During transportation, stability is also the key. It is necessary to prevent its shock and collision. The structure of this medicine may change due to severe shock, and the efficacy of the medicine will be affected. When padded with a soft object, it should be properly fixed to ensure its stability.
And the transportation equipment also needs to be cleaned. If impurities are mixed in, the purity of the medicine will change, and accidents may occur. It is appropriate to clean the equipment first and then inject the medicine.
All of these should be done cautiously in order to preserve the quality and efficacy of 4-alkane-3- (triethylmethyl) phenylisopropanol and avoid the risk of accidents.
When hiding, the first environment is heavy. It must be placed in a cool, dry and well ventilated place. This medicine is easy to decompose when heated. If it is placed in a high temperature, the efficacy of the medicine will quickly lose and it will be unusable. It is also afraid of moisture, and moisture will easily cause it to deliquescence and damage its quality. Therefore, it is necessary to hide in a dry place to preserve its quality.
Furthermore, it is also necessary to avoid light. Light can promote its chemical reaction, and the ingredients that cause the medicine will become easy, and the efficacy of the medicine will be damaged. When hiding with dark-colored utensils, or in a dark room, avoid the harm of light.
When losing, protection should not be ignored. The operator must wear appropriate protective equipment, such as gloves, masks, goggles, etc. This medicine may be irritating, and it can cause injury when it touches the skin, enters the mouth and nose. If you accidentally touch it, rinse it with plenty of water quickly, and seek medical attention if necessary.
During transportation, stability is also the key. It is necessary to prevent its shock and collision. The structure of this medicine may change due to severe shock, and the efficacy of the medicine will be affected. When padded with a soft object, it should be properly fixed to ensure its stability.
And the transportation equipment also needs to be cleaned. If impurities are mixed in, the purity of the medicine will change, and accidents may occur. It is appropriate to clean the equipment first and then inject the medicine.
All of these should be done cautiously in order to preserve the quality and efficacy of 4-alkane-3- (triethylmethyl) phenylisopropanol and avoid the risk of accidents.
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