Linshang Chemical
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Benzeneacetonitrile, 5-Chloro-2-Methoxy-
Linshang Chemical
|
HS Code |
951881 |
| Chemical Formula | C9H8ClNO |
| Molecular Weight | 181.62 |
| Appearance | Solid (usually) |
| Odor | Typically has a characteristic organic odor |
| Solubility In Water | Low solubility in water |
| Solubility In Organic Solvents | Soluble in many organic solvents like ethanol, acetone |
| Melting Point | Varies, but can be in a specific temperature range |
| Boiling Point | Exists at a particular boiling point |
| Density | Has a specific density value |
| Flash Point | Has a flash point relevant for safety |
As an accredited Benzeneacetonitrile, 5-Chloro-2-Methoxy- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 kg of 5 - chloro - 2 - methoxy - benzeneacetonitrile in a sealed chemical - grade drum. |
| Storage | Store “5 - chloro - 2 - methoxy - benzeneacetonitrile” in a cool, dry, well - ventilated area away from heat, flames, and ignition sources. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials like glass or high - density polyethylene. Isolate it from incompatible substances such as strong oxidizing agents and bases to prevent reactions. Label the storage clearly for easy identification and safety. |
| Shipping | Benzeneacetonitrile, 5 - chloro - 2 - methoxy - should be shipped in accordance with hazardous chemical regulations. Use proper, leak - proof containers. Ensure it's labeled clearly and transported by approved carriers following safety protocols. |
Competitive Benzeneacetonitrile, 5-Chloro-2-Methoxy- prices that fit your budget—flexible terms and customized quotes for every order.
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As a leading Benzeneacetonitrile, 5-Chloro-2-Methoxy- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the chemical properties of 5-chloro-2-methoxyphenylacetonitrile?
5-Bromo-2-methoxyphenylacetamide is one of the organic compounds. Its chemical properties are unique and related to many chemical reactions and characteristics.
In this compound, the bromine atom, methoxy group and phenylacetamide group interact to create its unique chemical activity. Bromine atoms have a certain nucleophilic substitution activity. Because of their high electronegativity, they can participate in nucleophilic substitution reactions as a leaving group under appropriate conditions. For example, when encountering nucleophilic reagents, nucleophilic testers can attack carbon atoms connected to bromine and replace bromine to form new organic compounds. The existence of the
methoxy group also has a significant impact on the properties of this compound. The electron cloud density of the benzene ring can be increased by the conjugation effect and induction effect. This not only affects the activity and positional selectivity of the substitution reaction on the benzene ring, but also affects the stability of the whole molecule. In the aromatic electrophilic substitution reaction, the methoxy group increases the electron cloud density of the ortho and para-sites of the benzene ring more significantly, so the electrophilic reagents are more inclined to attack the ortho and para-sites.
Phenylacetamide groups endow compounds with certain biological activity and chemical stability. The amide bond has a resonant structure and is relatively stable. It can maintain its own structure under many chemical reaction conditions. However, under strong acid or strong base conditions, the amide bond can undergo hydrolysis reaction to generate corresponding acids and amines.
In addition, the physical properties of 5-bromo-2-methoxyphenylacetamide, such as melting point, boiling point, solubility, etc., are also closely related to its chemical properties. Its solubility in organic solvents may vary depending on molecular polarity, which is of great significance for its separation, purification and environmental selection for participating in chemical reactions. In short, 5-bromo-2-methoxyphenylacetamide has rich chemical properties and may have important applications and research value in organic synthesis, pharmaceutical chemistry and other fields.
In this compound, the bromine atom, methoxy group and phenylacetamide group interact to create its unique chemical activity. Bromine atoms have a certain nucleophilic substitution activity. Because of their high electronegativity, they can participate in nucleophilic substitution reactions as a leaving group under appropriate conditions. For example, when encountering nucleophilic reagents, nucleophilic testers can attack carbon atoms connected to bromine and replace bromine to form new organic compounds. The existence of the
methoxy group also has a significant impact on the properties of this compound. The electron cloud density of the benzene ring can be increased by the conjugation effect and induction effect. This not only affects the activity and positional selectivity of the substitution reaction on the benzene ring, but also affects the stability of the whole molecule. In the aromatic electrophilic substitution reaction, the methoxy group increases the electron cloud density of the ortho and para-sites of the benzene ring more significantly, so the electrophilic reagents are more inclined to attack the ortho and para-sites.
Phenylacetamide groups endow compounds with certain biological activity and chemical stability. The amide bond has a resonant structure and is relatively stable. It can maintain its own structure under many chemical reaction conditions. However, under strong acid or strong base conditions, the amide bond can undergo hydrolysis reaction to generate corresponding acids and amines.
In addition, the physical properties of 5-bromo-2-methoxyphenylacetamide, such as melting point, boiling point, solubility, etc., are also closely related to its chemical properties. Its solubility in organic solvents may vary depending on molecular polarity, which is of great significance for its separation, purification and environmental selection for participating in chemical reactions. In short, 5-bromo-2-methoxyphenylacetamide has rich chemical properties and may have important applications and research value in organic synthesis, pharmaceutical chemistry and other fields.
What are the physical properties of 5-chloro-2-methoxyphenylacetonitrile?
5-% -2-methoxybenzyl ethyl ether is a unique chemical compound. Its physical properties are very special, let me describe it.
First of all, it is often a liquid of color to light color, clear and flowing, and can be flooded in sunlight, just like a faint autumn water. Its taste is very special, slightly aromatic, but it is not a strong and pungent fragrance, but like a light and elegant breath, just like the fragrance of a long forest in spring.
and the melting of boiling, the melting of this compound is low, and it is liquid under normal conditions, so it has a certain quality. The characteristics of this boiling process make it necessary to precisely control in some processes or operations to ensure its stability.
Solubility is also one of its important physical properties. 5-% -2-methoxybenzyl ethyl ether can be well dissolved in multiple solutions, such as ethanol and ether. Just like the water, the solubility in water is very small. However, the solubility in water is very small, and the water content of the two meets, such as oil and water.
Furthermore, its density can also be low. The phase of water has a slight density. If it enters the water, it can float on the water surface to form a thin and clear liquid film. This characteristic can be used in some separation operations for the purpose of separation.
In addition, the viscosity of 5-% -2-methoxy benzyl ethyl ether also has its own characteristics. It is neither viscous nor thin like water. Between the two, it presents a specific surface in terms of flow adhesion, etc., and has a certain impact on the workmanship of the phase or the reaction of the material.
First of all, it is often a liquid of color to light color, clear and flowing, and can be flooded in sunlight, just like a faint autumn water. Its taste is very special, slightly aromatic, but it is not a strong and pungent fragrance, but like a light and elegant breath, just like the fragrance of a long forest in spring.
and the melting of boiling, the melting of this compound is low, and it is liquid under normal conditions, so it has a certain quality. The characteristics of this boiling process make it necessary to precisely control in some processes or operations to ensure its stability.
Solubility is also one of its important physical properties. 5-% -2-methoxybenzyl ethyl ether can be well dissolved in multiple solutions, such as ethanol and ether. Just like the water, the solubility in water is very small. However, the solubility in water is very small, and the water content of the two meets, such as oil and water.
Furthermore, its density can also be low. The phase of water has a slight density. If it enters the water, it can float on the water surface to form a thin and clear liquid film. This characteristic can be used in some separation operations for the purpose of separation.
In addition, the viscosity of 5-% -2-methoxy benzyl ethyl ether also has its own characteristics. It is neither viscous nor thin like water. Between the two, it presents a specific surface in terms of flow adhesion, etc., and has a certain impact on the workmanship of the phase or the reaction of the material.
What are the main uses of 5-chloro-2-methoxyphenylacetonitrile?
5-Bromo-2-methoxyphenylacetamide is an important intermediate in organic synthesis and has key uses in many fields such as medicine, pesticides and materials science.
In the field of medicine, it is often used as a key raw material for drug synthesis. In the development of many drugs, 5-bromo-2-methoxyphenylacetamide needs to build a specific chemical structure to endow the drug with specific physiological activities and pharmacological effects. For some drugs with antibacterial and anti-inflammatory effects, the synthesis process will use this compound to interact with specific targets of organisms through its structural properties, and then achieve the purpose of treating diseases.
In the field of pesticides, 5-bromo-2-methoxyphenylacetamide also plays an important role. It can be used as a key intermediate for the synthesis of high-efficiency and low-toxicity pesticides. By modifying and modifying its structure, pesticide products for specific pests or diseases can be developed. With its unique chemical structure, such pesticides can precisely act on specific physiological processes of pests or pathogens, inhibit their growth and reproduction, thus effectively preventing and controlling crop diseases and insect pests, ensuring crop yield and quality.
In the field of materials science, this compound can be used to prepare functional materials. Because it contains specific functional groups, it can participate in material polymerization reactions or modify the surface of materials, giving materials special properties such as optics, electricity or mechanics. For example, in the synthesis of some optoelectronic materials, 5-bromo-2-methoxyphenylacetamide can be introduced as a structural unit to improve the photoelectric conversion efficiency or stability of the material, providing a basis for the development and application of new materials.
In short, although 5-bromo-2-methoxyphenylacetamide is an organic small molecule, it has shown key value in many important fields by virtue of its unique chemical structure and reactivity, and is of great significance for promoting technological progress and product innovation in related fields.
In the field of medicine, it is often used as a key raw material for drug synthesis. In the development of many drugs, 5-bromo-2-methoxyphenylacetamide needs to build a specific chemical structure to endow the drug with specific physiological activities and pharmacological effects. For some drugs with antibacterial and anti-inflammatory effects, the synthesis process will use this compound to interact with specific targets of organisms through its structural properties, and then achieve the purpose of treating diseases.
In the field of pesticides, 5-bromo-2-methoxyphenylacetamide also plays an important role. It can be used as a key intermediate for the synthesis of high-efficiency and low-toxicity pesticides. By modifying and modifying its structure, pesticide products for specific pests or diseases can be developed. With its unique chemical structure, such pesticides can precisely act on specific physiological processes of pests or pathogens, inhibit their growth and reproduction, thus effectively preventing and controlling crop diseases and insect pests, ensuring crop yield and quality.
In the field of materials science, this compound can be used to prepare functional materials. Because it contains specific functional groups, it can participate in material polymerization reactions or modify the surface of materials, giving materials special properties such as optics, electricity or mechanics. For example, in the synthesis of some optoelectronic materials, 5-bromo-2-methoxyphenylacetamide can be introduced as a structural unit to improve the photoelectric conversion efficiency or stability of the material, providing a basis for the development and application of new materials.
In short, although 5-bromo-2-methoxyphenylacetamide is an organic small molecule, it has shown key value in many important fields by virtue of its unique chemical structure and reactivity, and is of great significance for promoting technological progress and product innovation in related fields.
What is the synthesis method of 5-chloro-2-methoxyphenylacetonitrile?
To prepare 5-bromo-2-methoxyphenylacetamide, you can do it according to the following method.
Take 2-methoxyacetophenone first, which is the starting material. Place it in an appropriate reaction vessel, add an appropriate amount of brominating reagent, such as bromine, and carry out the bromination reaction under suitable reaction conditions, such as in the presence of a specific temperature range and catalyst. During this reaction, bromine atoms are introduced into the benzene ring of 2-methoxyacetophenone to generate 5-bromo-2-methoxyacetophenone. The reaction conditions need to be carefully controlled to avoid side reactions such as excessive bromination, which affect the purity and yield of the product.
After 5-bromo-2-methoxyacetophenone is obtained, it is reacted with ammonia or amine reagents. Ammonia or amine reagents can undergo nucleophilic addition reaction with ketocarbonyl, and then dehydration and other processes to form 5-bromo-2-methoxyphenylacetamide. When reacting, it is necessary to pay attention to the amount of reagents, reaction temperature, reaction time and other factors, which have a great influence on the reaction process and product formation.
Another feasible method is to use 2-methoxybenzoic acid as the starting material. First, it is converted into an acid chloride, such as reacting with dichlorosulfoxide to form 2-methoxybenzoyl chloride. Then it is reacted with a brominating agent to introduce bromine atoms on the benzene ring to obtain 5-bromo-2-methoxybenzoyl chloride. Finally, 5-bromo-2-methoxybenzoyl chloride is reacted with amines such as methylamine and reacted with amides to form the target product 5-bromo-2-methoxyphenylacetamide.
In the preparation process, each step of the reaction requires strict control of the reaction conditions. After the reaction is completed, it is often necessary to use separation and purification methods such as distillation, recrystallization, and column chromatography to obtain high-purity 5-bromo-2-methoxyphenylacetamide to ensure that it meets the requirements for subsequent use.
Take 2-methoxyacetophenone first, which is the starting material. Place it in an appropriate reaction vessel, add an appropriate amount of brominating reagent, such as bromine, and carry out the bromination reaction under suitable reaction conditions, such as in the presence of a specific temperature range and catalyst. During this reaction, bromine atoms are introduced into the benzene ring of 2-methoxyacetophenone to generate 5-bromo-2-methoxyacetophenone. The reaction conditions need to be carefully controlled to avoid side reactions such as excessive bromination, which affect the purity and yield of the product.
After 5-bromo-2-methoxyacetophenone is obtained, it is reacted with ammonia or amine reagents. Ammonia or amine reagents can undergo nucleophilic addition reaction with ketocarbonyl, and then dehydration and other processes to form 5-bromo-2-methoxyphenylacetamide. When reacting, it is necessary to pay attention to the amount of reagents, reaction temperature, reaction time and other factors, which have a great influence on the reaction process and product formation.
Another feasible method is to use 2-methoxybenzoic acid as the starting material. First, it is converted into an acid chloride, such as reacting with dichlorosulfoxide to form 2-methoxybenzoyl chloride. Then it is reacted with a brominating agent to introduce bromine atoms on the benzene ring to obtain 5-bromo-2-methoxybenzoyl chloride. Finally, 5-bromo-2-methoxybenzoyl chloride is reacted with amines such as methylamine and reacted with amides to form the target product 5-bromo-2-methoxyphenylacetamide.
In the preparation process, each step of the reaction requires strict control of the reaction conditions. After the reaction is completed, it is often necessary to use separation and purification methods such as distillation, recrystallization, and column chromatography to obtain high-purity 5-bromo-2-methoxyphenylacetamide to ensure that it meets the requirements for subsequent use.
What are the precautions for 5-chloro-2-methoxyphenylacetonitrile in storage and transportation?
5-% bromo-2-methoxybenzylacetic acid is stored in the environment, so pay attention to the general situation. First, this physical property or the surrounding environment has an impact, and it must be packed and dense to prevent exposure. If there is any exposure, or contamination of land, water sources, and hygiene. Second, the degree of control is essential. This compound may be affected by the temperature of the wave, and it is suitable for storage and dryness to avoid high tides. Under the high temperature, it may cause chemical reactions, and its amount will be reduced, and even safety will be threatened. Third, other substances should not be ignored. 5-% bromo-2-methoxybenzylacetic acid is not oxidized, and the original material can be combined. Because of its chemical properties, it is easy to cause violent reactions, such as fire, explosion, etc. Fourth, people who are not well-versed will be affected. Familiar with the nature of this thing, the characteristics of danger and the method of emergency disposal. On the way, pay attention to the problem immediately. If there is any problem, immediately follow the case. Fifth, the fire protection leakage and emergency management of the hidden place. Once something happens, it can be done quickly, and the damage reduction will be minimized. In this way, 5-% bromo-2-methoxybenzylacetic acid can be stored in the environment, ensuring the safety of people and the safety of the environment.
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