Linshang Chemical
PRODUCTS
Benzenesulfonamide, 4-Chloro-3-Nitro-
Linshang Chemical
|
HS Code |
621037 |
| Chemical Formula | C6H5ClN2O4S |
| Molar Mass | 238.63 g/mol |
| Appearance | Yellow solid |
| Solubility In Water | Low solubility |
| Melting Point | 154 - 156 °C |
| Boiling Point | Decomposes before boiling |
| Odor | Odorless or very faint odor |
| Flash Point | N/A (non - flammable solid in common conditions) |
| Ph Aqueous Solution | Neutral (as a solid, but if solubilized in water, would be close to 7 as it is a sulfonamide derivative) |
As an accredited Benzenesulfonamide, 4-Chloro-3-Nitro- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100 - gram bottles containing 4 - chloro - 3 - nitro - benzenesulfonamide for chemical storage. |
| Storage | 4 - Chloro - 3 - nitrobenzenesulfonamide should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and incompatible substances such as strong oxidizers and bases. Store in a tightly sealed container to prevent moisture absorption and potential reactions, ensuring the chemical's stability and minimizing the risk of hazards. |
| Shipping | 4 - chloro - 3 - nitro - benzenesulfonamide is shipped in sealed, corrosion - resistant containers. These are carefully packed to prevent damage during transit, following strict chemical shipping regulations to ensure safety. |
Competitive Benzenesulfonamide, 4-Chloro-3-Nitro- prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy Benzenesulfonamide, 4-Chloro-3-Nitro- in China?
As a trusted Benzenesulfonamide, 4-Chloro-3-Nitro- manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading Benzenesulfonamide, 4-Chloro-3-Nitro- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the physical properties of 4-chloro-3-nitrobenzenesulfonamide?
4-Bromo-3-fluorobenzoylaniline is an organic compound with unique physical properties. It is a white to light yellow crystalline powder and is stable at room temperature and pressure.
From the melting point point, the melting point of this compound is in a certain range. The specific value varies due to purity and other factors, and is roughly at a relatively high temperature, which indicates that the intermolecular force is strong and the structure is relatively stable.
In terms of solubility, it is difficult to dissolve in water. Due to the large difference between molecular polarity and water molecular polarity, water is a strong polar solvent, while 4-bromo-3-fluorobenzoylaniline has a weak polarity. However, it is soluble in some organic solvents, such as dichloromethane, chloroform, N, N-dimethylformamide, etc., which facilitates its application in organic synthesis reactions. In these organic solvents, it can be uniformly dispersed, which is conducive to the reaction.
The density of 4-bromo-3-fluorobenzoyl aniline has a specific value. This physical property is crucial in operations involving mass and volume conversion, such as material measurement and reaction system design. Density reflects the mass of a substance per unit volume, which is of great significance for controlling its dosage in actual production and experiments.
In addition, the compound has a certain vapor pressure, but the vapor pressure is low at room temperature, which means that its volatility is relatively small, and under normal conditions, it is difficult to change from solid or liquid to gaseous escape, which is conducive to maintaining its stability during storage and use, reducing losses and latent risks caused by volatilization.
From the melting point point, the melting point of this compound is in a certain range. The specific value varies due to purity and other factors, and is roughly at a relatively high temperature, which indicates that the intermolecular force is strong and the structure is relatively stable.
In terms of solubility, it is difficult to dissolve in water. Due to the large difference between molecular polarity and water molecular polarity, water is a strong polar solvent, while 4-bromo-3-fluorobenzoylaniline has a weak polarity. However, it is soluble in some organic solvents, such as dichloromethane, chloroform, N, N-dimethylformamide, etc., which facilitates its application in organic synthesis reactions. In these organic solvents, it can be uniformly dispersed, which is conducive to the reaction.
The density of 4-bromo-3-fluorobenzoyl aniline has a specific value. This physical property is crucial in operations involving mass and volume conversion, such as material measurement and reaction system design. Density reflects the mass of a substance per unit volume, which is of great significance for controlling its dosage in actual production and experiments.
In addition, the compound has a certain vapor pressure, but the vapor pressure is low at room temperature, which means that its volatility is relatively small, and under normal conditions, it is difficult to change from solid or liquid to gaseous escape, which is conducive to maintaining its stability during storage and use, reducing losses and latent risks caused by volatilization.
What are the chemical properties of 4-chloro-3-nitrobenzenesulfonamide?
4-Bromo-3-fluorobenzaldehyde is an organic compound with unique chemical properties.
First of all, the aldehyde group is its key functional group, which is quite active. The carbon-oxygen double bond electron cloud in the aldehyde group is biased towards the oxygen atom, making the carbon atom partially positive and vulnerable to attack by nucleophiles. This property makes 4-bromo-3-fluorobenzaldehyde participate in many nucleophilic addition reactions, such as acid-catalyzed acetals with alcohols, which are often used as a means to protect aldehyde groups in organic synthesis. Reaction with Grignard reagents can form carbon-carbon bonds, which is an important path for growing carbon chains and synthesizing complex organic molecules.
Secondly, the presence of bromine and fluorine in the halogen atom also endows the compound with unique properties. Fluorine atoms are extremely electronegative, which will have a significant impact on the density distribution of electron clouds in the benzene ring, reducing the density of electron clouds in the adjacent and para-sites of the benzene ring, and then reducing the activity of the electrophilic substitution of the benzene ring, and the substitution reaction mainly occurs in the meta-site. Although bromine atoms are also electron-withdrawing groups, they are relatively weak compared to fluorine atoms, and they can undergo substitution reactions under specific conditions. For example, in the nucleophilic substitution reaction, bromine atoms can be replaced by other nucleophiles, thereby introducing different functional groups to achieve molecular structure modification and functional expansion.
Furthermore, 4-bromo-3-fluorobenzaldehyde has a certain polarity due to the difference in electronegativity of fluorine and bromine atoms, which affects its physical properties, such as solubility and boiling point. In organic solvents, it exhibits good solubility, and the difference in polarity makes it different from other compounds, and has potential application value in the fields of separation, purification and molecular identification.
In short, 4-bromo-3-fluorobenzaldehyde exists in aldehyde groups, bromine and fluorine atoms, integrates a variety of chemical activities, and is widely used in organic synthesis, medicinal chemistry, materials science and other fields. It is an important intermediate for the preparation of various functional compounds and materials.
First of all, the aldehyde group is its key functional group, which is quite active. The carbon-oxygen double bond electron cloud in the aldehyde group is biased towards the oxygen atom, making the carbon atom partially positive and vulnerable to attack by nucleophiles. This property makes 4-bromo-3-fluorobenzaldehyde participate in many nucleophilic addition reactions, such as acid-catalyzed acetals with alcohols, which are often used as a means to protect aldehyde groups in organic synthesis. Reaction with Grignard reagents can form carbon-carbon bonds, which is an important path for growing carbon chains and synthesizing complex organic molecules.
Secondly, the presence of bromine and fluorine in the halogen atom also endows the compound with unique properties. Fluorine atoms are extremely electronegative, which will have a significant impact on the density distribution of electron clouds in the benzene ring, reducing the density of electron clouds in the adjacent and para-sites of the benzene ring, and then reducing the activity of the electrophilic substitution of the benzene ring, and the substitution reaction mainly occurs in the meta-site. Although bromine atoms are also electron-withdrawing groups, they are relatively weak compared to fluorine atoms, and they can undergo substitution reactions under specific conditions. For example, in the nucleophilic substitution reaction, bromine atoms can be replaced by other nucleophiles, thereby introducing different functional groups to achieve molecular structure modification and functional expansion.
Furthermore, 4-bromo-3-fluorobenzaldehyde has a certain polarity due to the difference in electronegativity of fluorine and bromine atoms, which affects its physical properties, such as solubility and boiling point. In organic solvents, it exhibits good solubility, and the difference in polarity makes it different from other compounds, and has potential application value in the fields of separation, purification and molecular identification.
In short, 4-bromo-3-fluorobenzaldehyde exists in aldehyde groups, bromine and fluorine atoms, integrates a variety of chemical activities, and is widely used in organic synthesis, medicinal chemistry, materials science and other fields. It is an important intermediate for the preparation of various functional compounds and materials.
What are the main uses of 4-chloro-3-nitrobenzenesulfonamide?
4-Tritium-3-aminobenzenesulfonic acid barium salt, this substance is not recorded in "Tiangong Kaiji", but it is deduced from the chemical industry. Its use is mostly related to chemical synthesis and material preparation.
In the field of chemical synthesis, or can be used as an intermediate. Because its structure contains special groups, it can be combined with other compounds by means of chemical reaction to produce a variety of organic products. If it goes through a specific reaction process, it may be able to access a larger molecular structure, paving the way for the synthesis of complex organic compounds, and may be of critical significance in the preparation of fine chemicals such as medicines and pesticides.
involves the category of material preparation, or affects the properties of specific materials. It contains barium element, which is added during the preparation of some inorganic materials, or can change the crystal structure, electrical properties, optical properties, etc. For example, it is introduced into ceramic materials, or its sintering characteristics and mechanical properties can be adjusted; it is used in the preparation of optical materials, or it can adjust the optical parameters such as the refractive index and light transmittance of the material.
And because of its amino group and sulfonic acid group, or it has certain ion exchange properties and complexing ability. In some separation and purification processes, this characteristic can be used to adsorb and separate specific ions or compounds to achieve the purpose of material purification.
Although this material is not mentioned in "Tiangong Kaiwu", the technology of chemical industry is flourishing today, and the use of such compounds in various industrial fields is gradually emerging, which has made great contributions to promoting the progress of chemical technology and expanding the boundaries of material properties.
In the field of chemical synthesis, or can be used as an intermediate. Because its structure contains special groups, it can be combined with other compounds by means of chemical reaction to produce a variety of organic products. If it goes through a specific reaction process, it may be able to access a larger molecular structure, paving the way for the synthesis of complex organic compounds, and may be of critical significance in the preparation of fine chemicals such as medicines and pesticides.
involves the category of material preparation, or affects the properties of specific materials. It contains barium element, which is added during the preparation of some inorganic materials, or can change the crystal structure, electrical properties, optical properties, etc. For example, it is introduced into ceramic materials, or its sintering characteristics and mechanical properties can be adjusted; it is used in the preparation of optical materials, or it can adjust the optical parameters such as the refractive index and light transmittance of the material.
And because of its amino group and sulfonic acid group, or it has certain ion exchange properties and complexing ability. In some separation and purification processes, this characteristic can be used to adsorb and separate specific ions or compounds to achieve the purpose of material purification.
Although this material is not mentioned in "Tiangong Kaiwu", the technology of chemical industry is flourishing today, and the use of such compounds in various industrial fields is gradually emerging, which has made great contributions to promoting the progress of chemical technology and expanding the boundaries of material properties.
What are the preparation methods of 4-chloro-3-nitrobenzenesulfonamide?
4-Bromo-3-nitrobenzaldehyde is an important intermediate in organic synthesis. The following is the preparation method:
** With m-nitrotoluene as the starting material **:
1. ** Bromination reaction **: m-nitrotoluene reacts with bromine under appropriate conditions. First, m-nitrotoluene is placed in a reactor, iron powder or iron tribromide is used as the catalyst, and liquid bromine is slowly added dropwise under heating conditions. In this reaction, bromine atoms selectively replace hydrogen atoms at the phencyclomethyl ortho position to generate 4-bromo-3-nitrotoluene. The reaction principle is based on the localization effect of substituents on the benzene ring, and the nitro group is the meta-localization group, which makes the methyl ortho-electron cloud density relatively high and more prone to electrophilic substitution. The reaction chemical equation is:
\ (C_ {7} H_ {7} NO_ {2} + Br_ {2}\ xrightarrow [] {FeBr_ {3}} C_ {7} H_ {6} BrNO_ {2} + HBr\)
2. ** Oxidation reaction **: 4-bromo-3-nitrotoluene is oxidized to obtain the target product. Common oxidizing agents include acidic potassium permanganate solution or potassium dichromate solution. Taking acidic potassium permanganate as an example, 4-bromo-3-nitrotoluene is added to the reaction system containing acidic potassium permanganate and heated to reflux. Methyl groups are oxidized to aldehyde groups under the action of strong oxidants to obtain 4-bromo-3-nitrobenzaldehyde. The chemical equation is:
\ (5C_ {7} H_ {6} BrNO_ {2} + 6KMnO_ {4} + 9H_ {2} SO_ {4}\ rightarrow5C_ {7} H_ {4} BrNO_ {3} + 3K_ {2} SO_ {4} + 6MnSO_ {4} + 14H_ {2} O\)
** With 3-nitrobenzaldehyde as raw material **:
1. ** Bromination reaction **: In an appropriate solvent such as dichloromethane, add 3-nitrobenzaldehyde with an appropriate amount of brominating reagent such as N-bromosuccinimide (NBS), and add a small amount of initiator such as benzoyl peroxide, and heat or light to initiate the reaction. NBS provides bromine source, which produces bromine radical under the action of initiator, and then undergoes radical substitution reaction with 3-nitrobenzaldehyde. Bromine atoms are introduced at specific positions in the benzene ring to generate 4-bromo-3-nitrobenzaldehyde. This reaction has good selectivity and can reduce the occurrence of side reactions. The reaction equation is:
\ (C_ {7} H_ {5} NO_ {3} + NBS\ xrightarrow [] {initiator} C_ {7} H_ {4} BrNO_ {3} + HBr + succinimide\)
** With m-nitrotoluene as the starting material **:
1. ** Bromination reaction **: m-nitrotoluene reacts with bromine under appropriate conditions. First, m-nitrotoluene is placed in a reactor, iron powder or iron tribromide is used as the catalyst, and liquid bromine is slowly added dropwise under heating conditions. In this reaction, bromine atoms selectively replace hydrogen atoms at the phencyclomethyl ortho position to generate 4-bromo-3-nitrotoluene. The reaction principle is based on the localization effect of substituents on the benzene ring, and the nitro group is the meta-localization group, which makes the methyl ortho-electron cloud density relatively high and more prone to electrophilic substitution. The reaction chemical equation is:
\ (C_ {7} H_ {7} NO_ {2} + Br_ {2}\ xrightarrow [] {FeBr_ {3}} C_ {7} H_ {6} BrNO_ {2} + HBr\)
2. ** Oxidation reaction **: 4-bromo-3-nitrotoluene is oxidized to obtain the target product. Common oxidizing agents include acidic potassium permanganate solution or potassium dichromate solution. Taking acidic potassium permanganate as an example, 4-bromo-3-nitrotoluene is added to the reaction system containing acidic potassium permanganate and heated to reflux. Methyl groups are oxidized to aldehyde groups under the action of strong oxidants to obtain 4-bromo-3-nitrobenzaldehyde. The chemical equation is:
\ (5C_ {7} H_ {6} BrNO_ {2} + 6KMnO_ {4} + 9H_ {2} SO_ {4}\ rightarrow5C_ {7} H_ {4} BrNO_ {3} + 3K_ {2} SO_ {4} + 6MnSO_ {4} + 14H_ {2} O\)
** With 3-nitrobenzaldehyde as raw material **:
1. ** Bromination reaction **: In an appropriate solvent such as dichloromethane, add 3-nitrobenzaldehyde with an appropriate amount of brominating reagent such as N-bromosuccinimide (NBS), and add a small amount of initiator such as benzoyl peroxide, and heat or light to initiate the reaction. NBS provides bromine source, which produces bromine radical under the action of initiator, and then undergoes radical substitution reaction with 3-nitrobenzaldehyde. Bromine atoms are introduced at specific positions in the benzene ring to generate 4-bromo-3-nitrobenzaldehyde. This reaction has good selectivity and can reduce the occurrence of side reactions. The reaction equation is:
\ (C_ {7} H_ {5} NO_ {3} + NBS\ xrightarrow [] {initiator} C_ {7} H_ {4} BrNO_ {3} + HBr + succinimide\)
What are the precautions for storing and transporting 4-chloro-3-nitrobenzenesulfonamide?
4-Tritium-3-fluorobenzaldehyde oxime requires careful attention during storage and transportation.
When storing, choose the first environment. It should be placed in a cool and ventilated warehouse, away from fires and heat sources. This is because the substance may have certain chemical activity, high temperature and open flame are prone to danger. The temperature and humidity of the warehouse should also be strictly controlled to prevent it from deteriorating due to temperature and humidity discomfort or causing other chemical reactions. And it needs to be stored separately from oxidants, acids, bases, etc., and must not be mixed. Due to its special chemical properties, contact with the above substances may cause violent reactions, endangering safety.
Furthermore, storage containers are also crucial. Be sure to use a well-sealed container to prevent material leakage. At the same time, the material of the container must be compatible with 4-tritium-3-fluorobenzaldehyde oxime to avoid chemical reactions between the two and affect the quality of the material.
When transporting, the qualifications of personnel cannot be ignored. Transporters must undergo special training and be familiar with relevant safety knowledge and emergency treatment methods. Transportation vehicles must also be in good condition and equipped with corresponding fire fighting equipment and leakage emergency treatment equipment.
During transportation, you should drive slowly to avoid bumps, vibrations and collisions. This substance may increase the risk of reaction under turbulent conditions. And transportation route planning should also be careful to avoid densely populated areas and traffic arteries to prevent major casualties and environmental pollution in the event of accidents.
When loading and unloading, be sure to operate with caution. Light loading and light unloading, it is strictly forbidden to drop and heavy pressure to prevent material leakage caused by damage to the container. In the event of a leak, the on-site personnel must take immediate emergency measures to evacuate the surrounding people, seal the scene, and deal with it according to the established plan.
When storing, choose the first environment. It should be placed in a cool and ventilated warehouse, away from fires and heat sources. This is because the substance may have certain chemical activity, high temperature and open flame are prone to danger. The temperature and humidity of the warehouse should also be strictly controlled to prevent it from deteriorating due to temperature and humidity discomfort or causing other chemical reactions. And it needs to be stored separately from oxidants, acids, bases, etc., and must not be mixed. Due to its special chemical properties, contact with the above substances may cause violent reactions, endangering safety.
Furthermore, storage containers are also crucial. Be sure to use a well-sealed container to prevent material leakage. At the same time, the material of the container must be compatible with 4-tritium-3-fluorobenzaldehyde oxime to avoid chemical reactions between the two and affect the quality of the material.
When transporting, the qualifications of personnel cannot be ignored. Transporters must undergo special training and be familiar with relevant safety knowledge and emergency treatment methods. Transportation vehicles must also be in good condition and equipped with corresponding fire fighting equipment and leakage emergency treatment equipment.
During transportation, you should drive slowly to avoid bumps, vibrations and collisions. This substance may increase the risk of reaction under turbulent conditions. And transportation route planning should also be careful to avoid densely populated areas and traffic arteries to prevent major casualties and environmental pollution in the event of accidents.
When loading and unloading, be sure to operate with caution. Light loading and light unloading, it is strictly forbidden to drop and heavy pressure to prevent material leakage caused by damage to the container. In the event of a leak, the on-site personnel must take immediate emergency measures to evacuate the surrounding people, seal the scene, and deal with it according to the established plan.
Scan to WhatsApp
