Linshang Chemical
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Benzenesulfonyl Chloride, 4-Bromo-2-Chloro-
Linshang Chemical
|
HS Code |
575907 |
| Chemical Formula | C6H3BrClO2S |
| Molar Mass | 271.51 g/mol |
| Appearance | White to off - white solid |
| Boiling Point | Approximately 302 - 304 °C |
| Melting Point | 66 - 68 °C |
| Solubility In Water | Reacts with water |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform |
| Vapor Pressure | Low at room temperature |
As an accredited Benzenesulfonyl Chloride, 4-Bromo-2-Chloro- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 4 - bromo - 2 - chloro - benzenesulfonyl chloride in sealed chemical - grade bottle. |
| Storage | 4 - bromo - 2 - chlorobenzenesulfonyl chloride should be stored in a cool, dry, well - ventilated area away from heat, flames, and oxidizing agents. It should be kept in a tightly closed container, preferably made of corrosion - resistant materials. Due to its reactivity and potential toxicity, storage areas should be restricted and labeled clearly to prevent accidental exposure. |
| Shipping | 4 - bromo - 2 - chloro - benzenesulfonyl chloride is a hazardous chemical. It must be shipped in accordance with strict regulations. Use appropriate packaging, label clearly, and ensure compliance with transportation safety standards for chemicals. |
Competitive Benzenesulfonyl Chloride, 4-Bromo-2-Chloro- prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy Benzenesulfonyl Chloride, 4-Bromo-2-Chloro- in China?
As a trusted Benzenesulfonyl Chloride, 4-Bromo-2-Chloro- manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading Benzenesulfonyl Chloride, 4-Bromo-2-Chloro- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 4-bromo-2-chlorobenzenesulfonyl chloride?
The main use of 4-2-2-1 sand is in the fields of medicine, disease, and coloring.
The matter of Dan's cultivation has been important since ancient times. Alchemists make pills in order to grow, and sand is often used as an important material because of its characteristics. It contains special ingredients. In the process of cultivation, it may be able to lead to wonderful transformation and help alchemists to pursue the pills of life in the world.
As for diseases, the use of sand is also not small. There are many ancient books in China, which have the functions of calming the mind, clearing and detoxifying. The disease of insomnia and madness in the heart, which can be used for good. However, its nature is slightly cold and slightly poisonous, so when using it, it must be followed, and the amount should be carefully controlled to ensure safety.
Furthermore, in terms of coloring, the color of the sand should be the color of its eyes, and it will be affected by the family. This is the original work, and it is the upper danqing. Coloring with sand can add color to the surface and show a magnificent image of wealth. Among the names, there is no shortage of people who add color to it, leaving behind many works in the world.
In this case, the 4-2-2-1 sand is the same, and the fields of danqing, danqing, and danqing all have their irreplaceable and important uses. It is also a precious thing in heaven and earth.
The matter of Dan's cultivation has been important since ancient times. Alchemists make pills in order to grow, and sand is often used as an important material because of its characteristics. It contains special ingredients. In the process of cultivation, it may be able to lead to wonderful transformation and help alchemists to pursue the pills of life in the world.
As for diseases, the use of sand is also not small. There are many ancient books in China, which have the functions of calming the mind, clearing and detoxifying. The disease of insomnia and madness in the heart, which can be used for good. However, its nature is slightly cold and slightly poisonous, so when using it, it must be followed, and the amount should be carefully controlled to ensure safety.
Furthermore, in terms of coloring, the color of the sand should be the color of its eyes, and it will be affected by the family. This is the original work, and it is the upper danqing. Coloring with sand can add color to the surface and show a magnificent image of wealth. Among the names, there is no shortage of people who add color to it, leaving behind many works in the world.
In this case, the 4-2-2-1 sand is the same, and the fields of danqing, danqing, and danqing all have their irreplaceable and important uses. It is also a precious thing in heaven and earth.
What are the physical properties of 4-bromo-2-chlorobenzenesulfonyl chloride?
4-Cyanogen-2-fluorobenzaldehyde is a colorless to light yellow liquid. Its physical properties are briefly described below:
- ** Physical state and color **: It appears as a colorless to light yellow liquid at room temperature and pressure. This feature is convenient for intuitive identification and preliminary judgment.
- ** Odor **: It has a special odor, but there is no specific standard description for the odor, which requires actual contact and perception.
- ** Melting point and boiling point **: The melting point is about -18 ° C, and the boiling point is in the range of 220-222 ° C. The melting point indicates that below -18 ° C, 4-cyanogen-2-fluorobenzaldehyde will change from liquid to solid; the boiling point means that at 220-222 ° C, it will change from liquid to gaseous. These data are of great significance for the setting of storage and processing conditions, such as storage temperatures above -18 ° C to prevent solidification from affecting access; and in processes involving heat treatment, when the temperature is close to or reaches the boiling point, pay attention to its vaporization.
- ** Density **: The density is about 1.27g/cm ³, this data reflects its density relationship with water. The density of 4-cyanogen-2-fluorobenzaldehyde is greater than that of water. If mixed with water, it will sink to the bottom of the water. In the separation process of chemical production, preliminary separation can be achieved by stratification operation according to this characteristic.
- ** Solubility **: Slightly soluble in water, but better soluble in most organic solvents, such as ethanol, ether, dichloromethane, etc. This solubility characteristic determines that when selecting solvents in the reaction system, organic solvents should be given priority to ensure that 4-cyanogen-2-fluorobenzaldehyde can be fully dispersed and participate in the reaction. During the purification of substances, it can also take advantage of its solubility differences in different solvents to achieve the purpose of separation and purification by means of extraction.
- ** Stability **: Under normal temperature and pressure and conventional storage conditions, 4-cyanogen-2-fluorobenzaldehyde has certain stability. However, care should be taken to avoid contact with strong oxidants, strong alkalis and other substances, as chemical reactions may occur, resulting in changes in material properties. For example, during storage and transportation, make sure that the container does not contain strong oxidizing or strong alkaline substances to prevent residual substances from reacting with it.
- ** Physical state and color **: It appears as a colorless to light yellow liquid at room temperature and pressure. This feature is convenient for intuitive identification and preliminary judgment.
- ** Odor **: It has a special odor, but there is no specific standard description for the odor, which requires actual contact and perception.
- ** Melting point and boiling point **: The melting point is about -18 ° C, and the boiling point is in the range of 220-222 ° C. The melting point indicates that below -18 ° C, 4-cyanogen-2-fluorobenzaldehyde will change from liquid to solid; the boiling point means that at 220-222 ° C, it will change from liquid to gaseous. These data are of great significance for the setting of storage and processing conditions, such as storage temperatures above -18 ° C to prevent solidification from affecting access; and in processes involving heat treatment, when the temperature is close to or reaches the boiling point, pay attention to its vaporization.
- ** Density **: The density is about 1.27g/cm ³, this data reflects its density relationship with water. The density of 4-cyanogen-2-fluorobenzaldehyde is greater than that of water. If mixed with water, it will sink to the bottom of the water. In the separation process of chemical production, preliminary separation can be achieved by stratification operation according to this characteristic.
- ** Solubility **: Slightly soluble in water, but better soluble in most organic solvents, such as ethanol, ether, dichloromethane, etc. This solubility characteristic determines that when selecting solvents in the reaction system, organic solvents should be given priority to ensure that 4-cyanogen-2-fluorobenzaldehyde can be fully dispersed and participate in the reaction. During the purification of substances, it can also take advantage of its solubility differences in different solvents to achieve the purpose of separation and purification by means of extraction.
- ** Stability **: Under normal temperature and pressure and conventional storage conditions, 4-cyanogen-2-fluorobenzaldehyde has certain stability. However, care should be taken to avoid contact with strong oxidants, strong alkalis and other substances, as chemical reactions may occur, resulting in changes in material properties. For example, during storage and transportation, make sure that the container does not contain strong oxidizing or strong alkaline substances to prevent residual substances from reacting with it.
What are the chemical properties of 4-bromo-2-chlorobenzenesulfonyl chloride?
What are the chemical properties of 4-2-1-1-2-2-2-1-2-2-2-1-1-2-1-2-1-1-1-2-2-1-1-1-1-2-1-1-2-2-1-1-1-1-1-1-2-2-2-2-3-1-1-1-1-1-2-2-3-1-1-1-1-2-2-3-1-1-1-2-3-1-2-3-1-2-3-1-1-2-3-1-1-1-2-2-1-1-1-2-3-1-1-2-3-1-1-1-2-2-3-1-1-1-2-3-1-1-2-3-1-2-3-1-2-1
Furthermore, in the air, 4-2-2-3 can react to oxygen. As the temperature shifts over time, oxides are formed on the surface. The formation of this oxide also shows its chemical activity, which can combine with oxygen components in the air.
In addition, it can cause the reaction of part of the gold solution. If placed in a solution, such as a solution of sulfuric acid, 4-2-3 can be disposed from its solution. Inverse formula: 4-2-2-CuSO + CuSO → 4-2-2-CuSO of sulfuric acid + Cu. This is because the gold activity of 4-1-2-2-3-1-1-1-1-1-1-1-2-2-2-1-2-2-1-1 can be used in specific conditions. If the acid is not strong, it will also develop its chemical properties. If the oxidizer meets, it can generate phase and other substances.
Therefore, 4-1-2-2-2-3-1 has polychemical properties, and its activity and the reaction of chemicals are important in chemical research and engineering.
Furthermore, in the air, 4-2-2-3 can react to oxygen. As the temperature shifts over time, oxides are formed on the surface. The formation of this oxide also shows its chemical activity, which can combine with oxygen components in the air.
In addition, it can cause the reaction of part of the gold solution. If placed in a solution, such as a solution of sulfuric acid, 4-2-3 can be disposed from its solution. Inverse formula: 4-2-2-CuSO + CuSO → 4-2-2-CuSO of sulfuric acid + Cu. This is because the gold activity of 4-1-2-2-3-1-1-1-1-1-1-1-2-2-2-1-2-2-1-1 can be used in specific conditions. If the acid is not strong, it will also develop its chemical properties. If the oxidizer meets, it can generate phase and other substances.
Therefore, 4-1-2-2-2-3-1 has polychemical properties, and its activity and the reaction of chemicals are important in chemical research and engineering.
What are the synthesis methods of 4-bromo-2-chlorobenzenesulfonyl chloride?
4-Bromo-2-fluorobenzoyl fluoride is an important intermediate in organic synthesis, and there are many synthesis methods. Although the synthesis of this compound is not directly recorded in the ancient book Tiangong Kaiwu, according to the wisdom of the ancients and similar synthesis ideas, there may be the following ways:
First, 4-bromo-2-fluorobenzoic acid is used as the starting material and can be reacted with dichlorosulfoxide. In this reaction, the sulfur in dichlorosulfoxide is electrophilic and can attack the hydroxyl oxygen atom in the carboxyl group of benzoic acid. After a series of complex electron transfer, the hydroxyl group is replaced by chlorine to form 4-bromo-2-fluorobenzoyl chloride. During the reaction, it should be noted that dichlorosulfoxide is irritating and the reaction is exothermic. The temperature should be After generating 4-bromo-2-fluorobenzoyl chloride, it reacts with anhydrous potassium fluoride in a specific organic solvent such as N, N-dimethylformamide (DMF), and the fluoride ion nucleophilic replaces the chlorine atom to obtain 4-bromo-2-fluorobenzoyl fluoride. This step should ensure that the system is water-free, because moisture will hydrolyze the acyl chloride.
Second, starting from 4-bromo-2-fluorotoluene, side chain halogenation is carried out first. In the presence of light or an initiator, the methyl is gradually halogenated to 4-bromo-2-fluorobenzyl chloride, 4-bromo-2-fluorobenzyl dichloride, and finally 4-bromo-2-fluorobenzoyl chloride. The subsequent steps are the same as those described above after generating 4-bromo-2-fluorobenzoyl chloride from 4-bromo-2-fluorobenzoic acid as a raw material, that is, reacting with anhydrous potassium fluoride to obtain the target product. The starting material for this route is relatively easy to obtain, but the halogenation process requires precise control of the reaction conditions to obtain high-purity 4-bromo-2-fluorobenzoyl chloride.
Third, using suitable benzene ring derivatives as raw materials, bromine and fluorine-containing acyl groups are introduced through Fu-Ke acylation reaction. First, an acyl halide or acid anhydride containing bromine and fluorine is prepared. Under the catalysis of Lewis acid such as aluminum trichloride, it reacts with benzene ring derivatives to introduce acyl groups at specific positions in the benzene ring. This method requires precise design of the raw material structure, so that bromine and fluorine are in suitable positions, and the Fu-Ke acylation reaction may have regioselectivity problems. The reaction conditions need to be optimized to improve the yield of the target product.
First, 4-bromo-2-fluorobenzoic acid is used as the starting material and can be reacted with dichlorosulfoxide. In this reaction, the sulfur in dichlorosulfoxide is electrophilic and can attack the hydroxyl oxygen atom in the carboxyl group of benzoic acid. After a series of complex electron transfer, the hydroxyl group is replaced by chlorine to form 4-bromo-2-fluorobenzoyl chloride. During the reaction, it should be noted that dichlorosulfoxide is irritating and the reaction is exothermic. The temperature should be After generating 4-bromo-2-fluorobenzoyl chloride, it reacts with anhydrous potassium fluoride in a specific organic solvent such as N, N-dimethylformamide (DMF), and the fluoride ion nucleophilic replaces the chlorine atom to obtain 4-bromo-2-fluorobenzoyl fluoride. This step should ensure that the system is water-free, because moisture will hydrolyze the acyl chloride.
Second, starting from 4-bromo-2-fluorotoluene, side chain halogenation is carried out first. In the presence of light or an initiator, the methyl is gradually halogenated to 4-bromo-2-fluorobenzyl chloride, 4-bromo-2-fluorobenzyl dichloride, and finally 4-bromo-2-fluorobenzoyl chloride. The subsequent steps are the same as those described above after generating 4-bromo-2-fluorobenzoyl chloride from 4-bromo-2-fluorobenzoic acid as a raw material, that is, reacting with anhydrous potassium fluoride to obtain the target product. The starting material for this route is relatively easy to obtain, but the halogenation process requires precise control of the reaction conditions to obtain high-purity 4-bromo-2-fluorobenzoyl chloride.
Third, using suitable benzene ring derivatives as raw materials, bromine and fluorine-containing acyl groups are introduced through Fu-Ke acylation reaction. First, an acyl halide or acid anhydride containing bromine and fluorine is prepared. Under the catalysis of Lewis acid such as aluminum trichloride, it reacts with benzene ring derivatives to introduce acyl groups at specific positions in the benzene ring. This method requires precise design of the raw material structure, so that bromine and fluorine are in suitable positions, and the Fu-Ke acylation reaction may have regioselectivity problems. The reaction conditions need to be optimized to improve the yield of the target product.
What should be paid attention to when storing and transporting 4-bromo-2-chlorobenzenesulfonyl chloride?
4-Cyanobenzoyl-2-fluorobenzoyl chloride Cyanobenzoyl chloride When storing and shipping, pay attention to the following ends:
First, it concerns the packaging. Cyanobenzoyl chloride is corrosive and chemically active, so the packaging must be tight. When it is made of corrosion-resistant materials, such as special plastic drums or iron drums lined with anti-corrosion coatings. The seal of the package must be well sealed to prevent leakage. This is because if it leaks, it will not only cause pollution to the surrounding environment, but also cause poisoning to contacts due to the toxicity of the substance.
Second, about the storage environment. It should be stored in a cool, dry and well-ventilated place. It is necessary to keep away from fire and heat sources. This is because cyanofluorobenzoyl chloride is easily decomposed by heat, and even causes dangerous chemical reactions, causing the risk of explosion. At the same time, humidity also needs to be strictly controlled, because it is prone to hydrolysis in contact with water, resulting in product deterioration, and hydrolysis products may be more dangerous. In addition, the substance should be stored separately from oxidants, alkalis, etc., and must not be mixed. It is prone to violent chemical reactions when in contact with these substances.
Third, in the transportation process. Transportation vehicles need to have corresponding safety protection facilities, such as leakage emergency treatment equipment and fire fighting equipment. During transportation, ensure that the container does not leak, collapse, fall, or damage. Avoid bumps and sudden braking when driving to prevent damage to the packaging. And transport personnel must be professionally trained to be familiar with the dangerous characteristics of cyanofluorobenzoyl chloride and emergency treatment methods. When loading and unloading, it should also be handled lightly. It is strictly forbidden to drop, drag and other rough operations to avoid leakage accidents.
First, it concerns the packaging. Cyanobenzoyl chloride is corrosive and chemically active, so the packaging must be tight. When it is made of corrosion-resistant materials, such as special plastic drums or iron drums lined with anti-corrosion coatings. The seal of the package must be well sealed to prevent leakage. This is because if it leaks, it will not only cause pollution to the surrounding environment, but also cause poisoning to contacts due to the toxicity of the substance.
Second, about the storage environment. It should be stored in a cool, dry and well-ventilated place. It is necessary to keep away from fire and heat sources. This is because cyanofluorobenzoyl chloride is easily decomposed by heat, and even causes dangerous chemical reactions, causing the risk of explosion. At the same time, humidity also needs to be strictly controlled, because it is prone to hydrolysis in contact with water, resulting in product deterioration, and hydrolysis products may be more dangerous. In addition, the substance should be stored separately from oxidants, alkalis, etc., and must not be mixed. It is prone to violent chemical reactions when in contact with these substances.
Third, in the transportation process. Transportation vehicles need to have corresponding safety protection facilities, such as leakage emergency treatment equipment and fire fighting equipment. During transportation, ensure that the container does not leak, collapse, fall, or damage. Avoid bumps and sudden braking when driving to prevent damage to the packaging. And transport personnel must be professionally trained to be familiar with the dangerous characteristics of cyanofluorobenzoyl chloride and emergency treatment methods. When loading and unloading, it should also be handled lightly. It is strictly forbidden to drop, drag and other rough operations to avoid leakage accidents.
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