Chloro-M-Nitrobenzene

Linshang Chemical

Specifications

HS Code

848600

Chemical Formula C6H4ClNO2
Molar Mass 157.55 g/mol
Appearance Yellow - brown crystalline solid
Odor Characteristic odor
Density 1.348 g/cm³ (at 20 °C)
Melting Point 46 - 48 °C
Boiling Point 235 - 236 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in ethanol, ether, benzene
Flash Point 110 °C
Vapor Pressure Low vapor pressure at room temperature
Stability Stable under normal conditions

As an accredited Chloro-M-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500 - gram bottles of Chloro - m - nitrobenzene, securely sealed for chemical storage.
Storage Chloro - m - nitrobenzene should be stored in a cool, dry, well - ventilated area, away from sources of ignition and heat. Keep it in tightly closed containers to prevent vapor release. Store it separately from oxidizing agents, reducing agents, and strong bases to avoid dangerous reactions. Regularly inspect storage areas for any signs of leakage.
Shipping Chloro - m - nitrobenzene is shipped in accordance with strict hazardous chemical regulations. It's typically transported in specialized containers, ensuring proper containment and protection during transit to prevent spills and risks.
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Chloro-M-Nitrobenzene Chloro-M-Nitrobenzene
General Information
Where to Buy Chloro-M-Nitrobenzene in China?
As a trusted Chloro-M-Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading Chloro-M-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of Chloro-m-nitrobenzene?
Chloro-m-nitrobenzene has a wide range of uses. In the chemical industry, it is a key raw material for organic synthesis. It can be used to prepare a variety of pharmaceutical, pesticide and dye compounds.
In terms of medicine, it can provide an important intermediate for the synthesis of many drugs. Taking the synthesis of specific drugs as an example, through the series of chemical reactions participated by chloro-m-nitrobenzene, structural units with specific pharmacological activities can be obtained, and then effective drugs for the treatment of diseases can be synthesized.
In terms of pesticides, its role is also indispensable. It can be transformed through a series of transformations to produce pesticide products with insecticidal, weeding and other effects. For example, in the synthesis of a new type of insecticide, chloro-m-nitrobenzene is used as the starting material. After carefully designed reaction steps, the product is given high-efficiency insecticidal performance and has little impact on the environment.
In the field of dyes, chloro-m-nitrobenzene provides the basis for the synthesis of dyes with bright colors and good stability. By chemically modifying and reacting it, dyes suitable for dyeing different fiber materials can be prepared. Fibers such as cotton, linen, silk, etc. can be dyed with such dyes, resulting in bright and long-lasting colors.
In addition, in the study of organic synthetic chemistry, chloro-m-nitrobenzene is often used as a model compound for researchers to explore the reaction mechanism, optimize the synthesis method, and promote the development of organic synthetic chemistry. Therefore, chloro-m-nitrobenzene is of great value in many industries and has a profound impact on industrial production and scientific research.
What are the physical properties of Chloro-m-nitrobenzene?
Chlorine-m-nitrobenzene is also an organic compound. It has the following physical properties:
Looking at its properties, under normal conditions, it is a light yellow needle-like or prismatic crystal appearance. From the perspective of the eye, this shape can be obtained.
As for its melting point, it is about 32.5 ° C. When the temperature reaches this point, the state of matter begins to change, from solid to other states, which is one of the key temperatures for its state transition.
Boiling point, about 235 ° C. At this high temperature, chlorine-m-nitrobenzene converts into a gaseous state, which is an important characteristic of its large change of state under the action of heat.
On density, about 1.348g/cm ³. This value shows the amount of substances contained in the unit volume, reflecting the density of its texture.
Furthermore, its solubility is also an important physical property. In water, chlorine-m-nitrobenzene is extremely difficult to dissolve, but it can be soluble in most organic solvents, such as ethanol, ether, and benzene. This property is due to the interaction between its molecular structure and the solvent molecules. The molecular structure of organic solvents is more compatible with chlorine-m-nitrobenzene, so it can be miscible, while the structure of water is quite different, so it is insoluble.
In addition, chlorine-m-nitrobenzene has a certain volatility. In the air, its molecules can escape, but the volatilization rate varies according to environmental conditions, such as temperature, air circulation and other factors. Its smell is also special, which can be felt by ordinary people. However, the description of its smell is difficult to describe, because individual olfactory feelings are slightly different. But generally speaking, its smell is pungent and a specific chemical smell. Such physical properties are important factors to consider in many fields such as chemical industry and scientific research, and are also related to its application, storage and transportation.
What is the chemistry of Chloro-m-nitrobenzene?
Chloro-m-nitrobenzene is also an organic compound. It is active, because it contains chlorine and nitro groups.
Let's talk about chlorine atoms first, which have unique effects in molecules. Chlorine atoms have electron-absorbing properties, resulting in a decrease in the electron cloud density of the benzene ring. This property makes the activity of the electrophilic substitution reaction of the benzene ring weaker, and such reactions are more difficult to occur than benzene. However, the electron cloud density of the adjacent and para-position is slightly higher than that of the meta-position, so during the electrophilic substitution reaction, the new group mostly enters the meta-position.
Then talk about the nitro group, which is also a strong electron-absorbing group. The synergy between the nitro group and the chlorine atom makes the electron cloud density of the benzene ring Due to the decrease in the electron cloud density of the benzene ring, it is favorable for the attack of nucleophilic reagents. Chloro-m-nitrobenzene is more prone to nucleophilic substitution. If it reacts with the nucleophilic reagent sodium alcohol, it can form ether compounds.
Its chemical stability is slightly weaker, and it is easy to decompose or react when heated or in contact with specific reagents. And chloro-m-nitrobenzene is toxic, and it should be used with caution during use and storage to prevent harm to the human body and the environment. Its chemical properties are complex, and it is widely used in the field of organic synthesis. It can be
What are Chloro-m-nitrobenzene production methods?
The method of making chlorine-m-nitrobenzene has been used by many parties throughout the ages, and the common ones are as follows.
First, take benzene as the starting material and perform nitrification first. Put benzene together with concentrated nitric acid and concentrated sulfuric acid, and under specific temperature conditions, the two react in phase to obtain nitrobenzene. In this process, nitric acid is catalyzed by sulfuric acid and turned into an active nitro positive ion, which then attacks the benzene ring and replaces one of its hydrogen atoms, resulting in nitrobenzene. Then, nitrobenzene is chlorinated. When a suitable catalyst, such as ferric chloride, is present, chlorine is introduced, and the chlorine atom will replace the hydrogen atom of the nitrobenzene interposition, and finally chlorine-m-nitrobenzene is obtained.
Second, m-nitroaniline can also be used as the starting material. Shilling m-nitroaniline reacts with sodium nitrite and hydrochloric acid at low temperature to form a diazonium salt. This diazonium salt is extremely active, and then added to the hydrochloric acid solution of cuprous chloride, the diazonium group will be replaced by chlorine atoms to obtain chloro-m-nitrobenzene. Although this method is slightly complicated, it is highly selective and can effectively obtain the target product.
Third, it can also be started from m-chlorobenzoic acid. First, m-chlorobenzoic acid is converted to its acid chloride form, and sulfoxide chloride is often used to react with it. Then, the acid chloride is reacted with ammonia to form an amide, which is then degraded by Hoffman. Under the action of bromine and sodium hydroxide, the amide is converted into an amine with one less carbon atom, that is, m-chloroaniline. Then m-chloroaniline is prepared as the above method to obtain diazonium salts, and then chlorine atoms are substituted for diazo groups to obtain chloro-m-nitrobenzene.
These several production methods have their own advantages and disadvantages, and they need to be carefully selected according to the actual product purity, cost, yield and many other factors.
Chloro-m-nitrobenzene what are the precautions during use
Chloro-m-nitrobenzene is also a commonly used raw material in the chemical industry. When using it, pay attention to it and be careful.
First, it is related to personal safety. This substance is toxic and can cause harm if it comes into contact with the human body or inhales its vapor. Therefore, when handling, protective gear is indispensable. Wear protective clothing, goggles, masks and gloves to avoid skin, eyes and respiratory organs from being invaded. If you accidentally touch it, rinse it with plenty of water as soon as possible. If the situation is serious, seek medical attention urgently.
Second, it is related to the risk of fire and explosion. Chloro-m-nitrobenzene is flammable, and there is a risk of explosion in case of open flames and hot topics. The storage place must be kept away from fire, heat sources, and well ventilated. When storing, it should be stored separately from oxidants and edible chemicals, and should not be mixed to prevent accidents. During the handling process, it is also necessary to handle it with care to avoid damage and leakage.
Third, it is related to environmental impact. If it leaks into the environment, it can cause pollution. In the event of a leak, quickly isolate the leak area and restrict personnel from entering and leaving. Emergency responders must wear protective equipment to prevent the spread of leaks. Small leaks can be swept away in dry, clean, covered containers; if there are large leaks, they need to build embankments or dig holes to contain them, absorb or absorb them with appropriate materials, and dispose of them properly. Do not allow pollution and soil.
Fourth, it is related to the operating specifications. During use, the operating procedures should be strictly followed, do not use in excess, and the operation room should be equipped with emergency treatment equipment and suitable fire equipment. After use, the equipment used should be washed and stored, and the residual materials should also be properly stored or disposed of. In this way, the safety of chloro-m-nitrobenzene can be guaranteed.
What are the main uses of Chloro-m-nitrobenzene?
Chloro-m-nitrobenzene has a wide range of uses. In the field of chemical industry, it is an important intermediate. It can be used to synthesize various medicines, such as some antibacterial drugs. By virtue of its chemical characteristics, it can be prepared through a series of reactions to obtain drugs with specific curative effects. It can also be used to prepare dyes. Its structure can endow the dye with unique color and stability, making the dyed product bright and lasting.
In the manufacture of pesticides, it is also very useful. After chemical modification, it can produce pesticides with insecticidal and weeding effects, protect crops from pests and diseases, and increase their yield. Furthermore, in the field of materials science, it can be used as raw materials to synthesize materials with special properties, such as some heat-resistant and corrosion-resistant polymer materials, to expand the scope of material applications. It is a key player in the chemical industry chain, serving as a hub for the production of many downstream products and making outstanding contributions to industrial development.
What are the physical properties of Chloro-m-nitrobenzene?
Chloro-m-nitrobenzene is also an organic compound. It has unique physical properties. Looking at its appearance, it is a yellow needle-like or rib-like crystal at room temperature, with a bright and regular color.
When it comes to the melting point, it is about 32 ° C. If the ambient temperature rises, this substance gradually melts from a solid state to a liquid state, just like ice melts when it is warm. Its boiling point is quite high, about 235 ° C. To boil it into a gaseous state, a high temperature needs to be applied.
As for the density, it is heavier than water, about 1.348g/cm ³, so if placed in water, it will sink to the bottom of the water, such as a stone falling into the abyss. And it is insoluble in water, the two meet, such as water and oil repel each other, and each does not blend. However, it is soluble in most organic solvents, such as ethanol, ether, etc., just like salt in water, it can be evenly dispersed in it.
Furthermore, chloro-m-nitrobenzene is volatile, can slowly escape in the air, and has a special odor, which can be distinguished by smell. These physical properties are of great significance in various fields of chemical industry and are the basis for its application.
What are the chemical properties of Chloro-m-nitrobenzene?
Chloro-m-nitrobenzene has several chemical properties. It is a derivative of aromatic hydrocarbons. On the benzene ring, chlorine is attached to m-nitro two groups.
This substance has certain stability, but under specific conditions, it can also react in various ways. As far as nucleophilic substitution is concerned, the nitro group has strong electron absorption, which can reduce the electron cloud density of the benzene ring and increase the activity of chlorine atoms. In case of suitable nucleophiles, such as sodium alcohol, amines, etc., chlorine atoms can be replaced by nucleophiles to form new compounds.
It can also participate in the reduction reaction, and the nitro group can be gradually reduced. With an appropriate reducing agent, such as iron and hydrochloric acid, nitro can be reduced to nitroso group first, and then reduced to amino group to obtain m-chloroaniline.
In the electrophilic substitution reaction, although the electron cloud density of the benzene ring decreases due to the nitro group, the reactivity is lower than that of benzene. However, because chlorine is an ortho-para-site group and nitro is an meta-site group, under the combined influence, the electrophilic substitution reaction mostly occurs between the ortho-site of chlorine and the nitro group.
Furthermore, it has certain solubility, is slightly soluble in water, and is soluble in most organic solvents, such as ethanol, ethyl ether, benzene, etc. This property is related to the polarity of the molecule.
In the field of organic synthesis, chloro-m-nitrobenzene is often an important intermediate, which can be used to construct organic compounds with different structures through various reaction paths, and is widely used in many industries such as medicine, pesticides, and dyes.
What is Chloro-m-nitrobenzene production method?
The method of making chloro-m-nitrobenzene has been around since ancient times. In the past, to make this substance, benzene was often used as the starting material. First, benzene is heated with nitric acid and sulfuric acid, and the method of nitrification is carried out. Under the catalysis of sulfuric acid, nitric acid can be the source of nitro groups, and the benzene ring is introduced to obtain nitrobenzene. This step requires careful control of the temperature and the ratio of reagents to ensure a smooth reaction and multiple mesophytes.
Then, the resulting nitrobenzene is reacted with chlorine gas in the presence of a catalyst. The catalyst used is often iron halide or the like. With the help of chlorine in the catalyst, it can replace the hydrogen atom on the benzene ring to obtain chloro- This reaction also requires fine regulation of the reaction conditions, such as temperature, chlorine gas entry rate, etc., so that the reaction proceeds in the desired direction and increases the yield of the target product.
Or there are other methods. Starting with m-nitroaniline, the amino group is changed to a diazo salt through the diazotization reaction. Then, reacting with reagents such as cuprous chloride, the diazo group can be replaced by chlorine atoms to obtain chloro-m-nitrobenzene. This method is slightly complicated, but in specific situations, it may have unique advantages and can be selected according to the actual situation. All these methods depend on the craftsman's fine operation and abiding by the rules of the reaction to obtain high-quality chloro-m-nitrobenzene.
Chloro-m-nitrobenzene What are the precautions during storage and transportation?
Chloro-m-nitrobenzene, as well as chemical substances, should be used with caution when storing and transporting.
When storing, the first warehouse conditions. It is necessary to choose a cool and ventilated place, away from fire and heat sources, so as to avoid heat and change. The temperature of the warehouse should be controlled in a suitable area and should not be too high to prevent its properties from changing. In addition, it should be stored separately from oxidizing agents and edible chemicals, and must not be mixed. Because of its different nature, there are also many requirements for transportation. Before loading, it is necessary to carefully check whether the packaging is in good condition and whether the seal is tight. If it is damaged, it must not be shipped to prevent leakage from causing harm. During transportation, the traffic should be stable to avoid its bumps and vibrations, so as to protect the integrity of its packaging. And the escort should be familiar with the properties of this thing, and in case of an emergency, they can respond quickly. Vehicles that are also transported should be equipped with corresponding emergency treatment equipment and protective equipment, just in case.
When loading and unloading, the operator must load and unload lightly, and must not drop, heavy pressure, or cause damage to the packaging. In short, the storage and transportation of chloro-m-nitrobenzene is related to safety, and everything needs to be done with caution and in accordance with regulations to be safe.