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((Chloromethyl)Sulphonyl)Benzene
Linshang Chemical
|
HS Code |
630042 |
| Chemical Formula | C7H7ClO2S |
| Molar Mass | 190.65 g/mol |
| Appearance | Solid |
| Melting Point | 48 - 50 °C |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane |
| Vapor Pressure | Low |
| Odor | Pungent |
| Hazard Class | Corrosive, toxic |
As an accredited ((Chloromethyl)Sulphonyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of (chloromethyl)sulphonylbenzene packaged in a sealed, chemical - resistant bottle. |
| Storage | (Chloromethyl)sulphonylbenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition points. Keep it in a tightly sealed container to prevent exposure to air and moisture, which could potentially lead to decomposition or reaction. Store it separately from incompatible substances like strong oxidizers and bases to avoid dangerous chemical reactions. |
| Shipping | (Chloromethyl)sulphonylbenzene is a chemical that requires careful shipping. It should be packed in appropriate, leak - proof containers. Shipment must comply with hazardous chemical regulations, ensuring proper labeling and handling to prevent risks during transit. |
Competitive ((Chloromethyl)Sulphonyl)Benzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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As a leading ((Chloromethyl)Sulphonyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the main use of (chloromethyl) sulphonyl benzene
(Chloromethyl) sulfonylbenzene has a wide range of uses. In the field of organic synthesis, it is a key intermediate. It can interact with different reagents through many reaction pathways to construct various complex organic molecular structures.
One of them is often used in nucleophilic substitution reactions. Due to the activity of chloromethyl in its structure, it is easily attacked by nucleophiles, thus introducing specific functional groups. For example, when reacted with alcohols, ether compounds can be formed, which is of great significance in drug synthesis and materials science. The construction of drug molecules often requires such ether bond structures to adjust the activity and solubility of drugs.
Second, it also plays an important role in the construction of sulfur-containing organic compounds. The presence of sulfonyl groups imparts unique chemical properties to the compound. Sulfonyl groups can be modified through further reactions to synthesize sulfur-containing organic materials with special functions, such as some high-performance polymer additives, which can improve the physical properties of polymers, such as enhancing their stability and improving their mechanical strength.
Third, it is also used in the field of material surface modification. (Chloromethyl) sulfonylbenzene can be grafted on the surface of the material through chemical reactions to change the chemical properties of the surface of the material, making it have better hydrophilicity, corrosion resistance and other characteristics. In coatings, textiles and other industries, through such modification methods, the quality and performance of products can be improved. Therefore, (chloromethyl) sulfonylbenzene plays an indispensable role in many fields such as organic synthesis and materials science, and has made significant contributions to the development of related fields.
One of them is often used in nucleophilic substitution reactions. Due to the activity of chloromethyl in its structure, it is easily attacked by nucleophiles, thus introducing specific functional groups. For example, when reacted with alcohols, ether compounds can be formed, which is of great significance in drug synthesis and materials science. The construction of drug molecules often requires such ether bond structures to adjust the activity and solubility of drugs.
Second, it also plays an important role in the construction of sulfur-containing organic compounds. The presence of sulfonyl groups imparts unique chemical properties to the compound. Sulfonyl groups can be modified through further reactions to synthesize sulfur-containing organic materials with special functions, such as some high-performance polymer additives, which can improve the physical properties of polymers, such as enhancing their stability and improving their mechanical strength.
Third, it is also used in the field of material surface modification. (Chloromethyl) sulfonylbenzene can be grafted on the surface of the material through chemical reactions to change the chemical properties of the surface of the material, making it have better hydrophilicity, corrosion resistance and other characteristics. In coatings, textiles and other industries, through such modification methods, the quality and performance of products can be improved. Therefore, (chloromethyl) sulfonylbenzene plays an indispensable role in many fields such as organic synthesis and materials science, and has made significant contributions to the development of related fields.
What are the physical properties of (chloromethyl) sulphonyl benzene
(Chloromethyl) sulfonylbenzene is one of the organic compounds. Its physical properties are quite worthy of investigation.
First of all, its properties, at room temperature, (chloromethyl) sulfonylbenzene is often solid, texture or crystalline, and it has a certain regular form. Its color is mostly white, and when it is pure, it is white and pure, just like the cleanliness of frost and snow.
Second, the melting point of this compound has a specific melting point. When the temperature rises to a certain value, it will change from solid to liquid. This melting point value is extremely critical when identifying and purifying the substance. It can provide an accurate reference for the experimenter to distinguish its purity.
Furthermore, its solubility is also an important physical property. In organic solvents, (chloromethyl) sulfonyl benzene may exhibit different solubility conditions. Some organic solvents, such as common ethanol, ether, etc., meet with it, or can dissolve the compound. However, in water, its solubility is poor, and it is difficult to miscible with water. This property is also related to the groups contained in its molecular structure.
In addition, its density is also a characterization of physical properties. With a certain density value, under the same conditions, it can be compared with the density of other substances, which is helpful in experimental operations or industrial production. Appropriate separation and purification methods are used according to density differences.
And its smell, although not very strong and pungent, still has its own unique smell, which can be used as a preliminary identification of the compound.
These are the physical properties of (chloromethyl) sulfonylbenzene, which are of great significance in the research, experiment and industrial application of organic chemistry.
First of all, its properties, at room temperature, (chloromethyl) sulfonylbenzene is often solid, texture or crystalline, and it has a certain regular form. Its color is mostly white, and when it is pure, it is white and pure, just like the cleanliness of frost and snow.
Second, the melting point of this compound has a specific melting point. When the temperature rises to a certain value, it will change from solid to liquid. This melting point value is extremely critical when identifying and purifying the substance. It can provide an accurate reference for the experimenter to distinguish its purity.
Furthermore, its solubility is also an important physical property. In organic solvents, (chloromethyl) sulfonyl benzene may exhibit different solubility conditions. Some organic solvents, such as common ethanol, ether, etc., meet with it, or can dissolve the compound. However, in water, its solubility is poor, and it is difficult to miscible with water. This property is also related to the groups contained in its molecular structure.
In addition, its density is also a characterization of physical properties. With a certain density value, under the same conditions, it can be compared with the density of other substances, which is helpful in experimental operations or industrial production. Appropriate separation and purification methods are used according to density differences.
And its smell, although not very strong and pungent, still has its own unique smell, which can be used as a preliminary identification of the compound.
These are the physical properties of (chloromethyl) sulfonylbenzene, which are of great significance in the research, experiment and industrial application of organic chemistry.
What are the chemical properties of (chloromethyl) sulphonyl benzene
(Chloromethyl) sulfonylbenzene is also an organic compound. Its properties are unique and have multiple chemical properties.
Looking at its structure, it contains chloromethyl and sulfonyl groups. Chloromethyl groups have strong chlorine atom activity and often lead to nucleophilic substitution reactions. Nucleophilic reagents such as alcohols and amines can interact with chlorine atoms of chloromethyl groups, and chlorine can leave and form new bonds, resulting in a variety of compounds. This is a common strategy for building carbon-heteroatom bonds in organic synthesis.
Sulfonyl groups also have characteristics, which have electron-absorbing properties and can reduce the electron cloud density of the benzene ring. In the aromatic electrophilic substitution reaction, blunt benzene ring is induced, the reaction conditions may be harsh, and the localization effect is unique, often guiding the substituent into the benzene ring interposition.
And because of its heteroatoms such as sulfur and oxygen, (chloromethyl) sulfonylbenzene can participate in a variety of reactions involving heteroatom chemistry. If coupled with metal-organic reagents, it can expand the carbon chain and build more complex organic structures.
(chloromethyl) sulfonylbenzene has rich chemical properties. In the field of organic synthesis, it can be used as a key intermediate to help chemists create many organic molecules with specific functions. It has potential applications in materials science, medicinal chemistry and other fields.
Looking at its structure, it contains chloromethyl and sulfonyl groups. Chloromethyl groups have strong chlorine atom activity and often lead to nucleophilic substitution reactions. Nucleophilic reagents such as alcohols and amines can interact with chlorine atoms of chloromethyl groups, and chlorine can leave and form new bonds, resulting in a variety of compounds. This is a common strategy for building carbon-heteroatom bonds in organic synthesis.
Sulfonyl groups also have characteristics, which have electron-absorbing properties and can reduce the electron cloud density of the benzene ring. In the aromatic electrophilic substitution reaction, blunt benzene ring is induced, the reaction conditions may be harsh, and the localization effect is unique, often guiding the substituent into the benzene ring interposition.
And because of its heteroatoms such as sulfur and oxygen, (chloromethyl) sulfonylbenzene can participate in a variety of reactions involving heteroatom chemistry. If coupled with metal-organic reagents, it can expand the carbon chain and build more complex organic structures.
(chloromethyl) sulfonylbenzene has rich chemical properties. In the field of organic synthesis, it can be used as a key intermediate to help chemists create many organic molecules with specific functions. It has potential applications in materials science, medicinal chemistry and other fields.
What are the synthesis methods of (chloromethyl) sulphonyl benzene
The method of synthesizing (chloromethyl) sulfonylbenzene has been widely studied throughout the ages. In the past, sulfonylbenzene was often used as a group to interact with chloromethylation reagents. For example, polyformaldehyde and hydrogen chloride are used as chloromethylation raw materials, in suitable solvents, such as dichloromethane and chloroform, accompanied by appropriate catalysts, such as anhydrous zinc chloride, aluminum trichloride, etc., heated and stirred, and after a reaction, (chloromethyl) sulfonylbenzene can be obtained.
And chloromethyl phenyl sulfide is used as the starting material and is prepared by oxidation. In this oxidation process, strong oxidants such as m-chloroperoxybenzoic acid and hydrogen peroxide can be used to oxidize thioether to sulfonyl group under suitable reaction conditions, and then obtain (chloromethyl) sulfonylbenzene.
There are also those who start with halogenated benzene, first introduce sulfonyl group through Fu-gram reaction, and then carry out chloromethylation reaction. During the Fu-gram reaction, a suitable sulfonyl chloride reagent is selected, and anhydrous aluminum trichloride is used as a catalyst to react in an aromatic hydrocarbon solvent to obtain a sulfonylbenzene derivative.
Each method has its own advantages and disadvantages. The methods of the past, or the reaction conditions are harsh, or the raw materials are rare, or the yield is not high. However, the wise ancestors made unremitting explorations on the way to synthesis, paving the foundation for future generations' research, so that future generations can be better than their predecessors, and constantly explore more efficient and convenient methods for synthesizing (chloromethyl) sulfonyl benzene.
And chloromethyl phenyl sulfide is used as the starting material and is prepared by oxidation. In this oxidation process, strong oxidants such as m-chloroperoxybenzoic acid and hydrogen peroxide can be used to oxidize thioether to sulfonyl group under suitable reaction conditions, and then obtain (chloromethyl) sulfonylbenzene.
There are also those who start with halogenated benzene, first introduce sulfonyl group through Fu-gram reaction, and then carry out chloromethylation reaction. During the Fu-gram reaction, a suitable sulfonyl chloride reagent is selected, and anhydrous aluminum trichloride is used as a catalyst to react in an aromatic hydrocarbon solvent to obtain a sulfonylbenzene derivative.
Each method has its own advantages and disadvantages. The methods of the past, or the reaction conditions are harsh, or the raw materials are rare, or the yield is not high. However, the wise ancestors made unremitting explorations on the way to synthesis, paving the foundation for future generations' research, so that future generations can be better than their predecessors, and constantly explore more efficient and convenient methods for synthesizing (chloromethyl) sulfonyl benzene.
What are the precautions for (chloromethyl) sulphonyl benzene during use?
For (chloromethyl) sulfonyl benzene, when using it, you must pay attention to all kinds of things. This is a chemical substance, which has a lively state, and should be used with caution.
The first one is related to safety protection. Because it may be irritating, it is in contact with the skin, eyes, and may cause damage. Therefore, when handling, you must wear protective equipment, such as gloves, goggles, etc., to avoid damage to the skin and eyes. And it is suitable for well-ventilated places to prevent its volatile gas from entering the mouth and nose and damaging the respiratory system.
Second, its chemical activity is quite high, mixed with other things, or a violent reaction. When using it, be sure not to mix it rashly to cause unexpected changes. If it coexists with strong oxidants, strong alkalis, etc., or there is a risk of danger, it should be avoided.
Furthermore, attention should also be paid to storage. It should be placed in a cool, dry place, away from fire and heat sources to prevent it from deteriorating or causing fire. And it must be sealed and stored to prevent it from contacting air and water vapor and causing chemical changes.
In addition, the treatment after use should not be ignored. Its remnants should not be disposed of at will, but should be properly disposed of in accordance with the regulations of chemical waste treatment to avoid pollution and the environment.
All of these are for those who should pay attention to the use of (chloromethyl) sulfonyl benzene, and those who handle it must keep it in mind to ensure safety and proper use.
The first one is related to safety protection. Because it may be irritating, it is in contact with the skin, eyes, and may cause damage. Therefore, when handling, you must wear protective equipment, such as gloves, goggles, etc., to avoid damage to the skin and eyes. And it is suitable for well-ventilated places to prevent its volatile gas from entering the mouth and nose and damaging the respiratory system.
Second, its chemical activity is quite high, mixed with other things, or a violent reaction. When using it, be sure not to mix it rashly to cause unexpected changes. If it coexists with strong oxidants, strong alkalis, etc., or there is a risk of danger, it should be avoided.
Furthermore, attention should also be paid to storage. It should be placed in a cool, dry place, away from fire and heat sources to prevent it from deteriorating or causing fire. And it must be sealed and stored to prevent it from contacting air and water vapor and causing chemical changes.
In addition, the treatment after use should not be ignored. Its remnants should not be disposed of at will, but should be properly disposed of in accordance with the regulations of chemical waste treatment to avoid pollution and the environment.
All of these are for those who should pay attention to the use of (chloromethyl) sulfonyl benzene, and those who handle it must keep it in mind to ensure safety and proper use.
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