Dimethyl 5-Chlorobenzene-1,3-Dicarboxylate
Linshang Chemical
HS Code |
191321 |
Chemical Formula | C10H9ClO4 |
Molecular Weight | 228.63 g/mol |
Appearance | Solid (likely white or off - white) |
Melting Point | Data may vary, but generally in a certain temperature range |
Boiling Point | Higher temperature due to its molecular structure |
Solubility In Water | Low solubility in water |
Solubility In Organic Solvents | Soluble in some common organic solvents like dichloromethane, ethyl acetate |
Density | Specific value depending on conditions |
Stability | Stable under normal conditions, but may react with strong oxidizing agents |
As an accredited Dimethyl 5-Chlorobenzene-1,3-Dicarboxylate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | Dimethyl 5 - chlorobenzene - 1,3 - dicarboxylate, 100g, packaged in a sealed plastic bottle. |
Storage | Dimethyl 5 - chlorobenzene - 1,3 - dicarboxylate should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition points. Keep it in a tightly - sealed container to prevent moisture and air exposure, which could potentially lead to chemical reactions. Store separately from incompatible substances, like oxidizing agents and strong bases. |
Shipping | Dimethyl 5 - chlorobenzene - 1,3 - dicarboxylate is shipped in well - sealed containers, following strict chemical transport regulations. Packaging ensures protection from physical damage and environmental exposure during transit. |
Competitive Dimethyl 5-Chlorobenzene-1,3-Dicarboxylate prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading Dimethyl 5-Chlorobenzene-1,3-Dicarboxylate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
First of all, the compound contains chlorine atoms and ester groups. Chlorine atoms have certain electronegativity, which can change the distribution of molecular electron clouds, which in turn affects their chemical activity. In many chemical reactions, chlorine atoms are prone to form a check point for nucleophilic substitution reactions. Nucleophiles can attack chlorine atoms and replace them, and then form novel carbon-heteroatomic bonds, whereby other compounds can be derived.
The ester group is also a key functional group. It can undergo hydrolysis under acidic or basic conditions. In acidic media, the hydrolysis reaction is relatively mild and gradually converts into carboxylic acids and alcohols; in alkaline environments, hydrolysis is more rapid and thorough, directly generating carboxylic salts and alcohols. This hydrolysis property is of great significance in the field of organic synthesis and medicinal chemistry, and can be used to prepare specific carboxylic acid derivatives, or as an intermediate step in organic synthesis.
Furthermore, the benzene ring structure of the compound gives it a certain conjugate system. The conjugate system enhances molecular stability and makes the molecule unique in spectral properties. For example, in the ultraviolet-visible spectrum, specific absorption peaks appear, which is an important basis for the analysis and identification of compounds.
In addition, since its molecular structure contains multiple substituents, steric hindrance is also one of the factors affecting its chemical properties. Different substituent spatial arrangements affect molecular interactions, such as van der Waals forces, hydrogen bonds, etc. This not only affects the physical properties of compounds, such as melting point, boiling point, etc., but also affects the reaction rate and selectivity in chemical reactions. For example, in areas with large steric hindrance, the difficulty of attacking nucleophiles will increase, which will affect the reaction process.
First, in the field of medicinal chemistry, it is often used as a key intermediate. The construction of many drug molecules depends on its unique chemical structure, which can be precisely modified and transformed through various chemical reactions to prepare compounds with specific pharmacological activities. By introducing different functional groups on the basis of its structure, new drugs targeting specific disease targets can be developed, such as the development of anti-tumor and anti-infection drugs. Dimethyl 5-chlorobenzene-1,3-dicarboxylate may play an indispensable role.
Second, in the field of materials science, it also shows important value. It can be used to synthesize special polymer materials, because its molecular structure gives the material unique physical and chemical properties. For example, it can improve the thermal stability, mechanical properties or optical properties of the material. Polymer materials synthesized from this material can be applied to electronic devices, optical instruments and other fields to meet the strict requirements of high-end technology on material properties.
Third, in the fine chemical industry, dimethyl 5-chlorobenzene-1,3-dicarboxylate can be used to prepare various fine chemicals, such as fragrances, dyes, etc. By chemically modifying it, it can impart a unique aroma to the fragrance, or bring excellent dyeing properties and color stability to the dye, thereby enhancing the quality and added value of fine chemical products.
Fourth, in the study of organic synthesis methodology, as a classic substrate, it is widely used to explore new reaction pathways and mechanisms. By studying the chemical reactions involved in it, researchers can expand the methods and strategies of organic synthesis, provide new ideas and methods for the development of organic chemistry, and promote organic synthesis chemistry to move towards a more efficient and greener direction.
The initial raw material is often 5-chloro-isophthalic acid. To convert it into dimethyl 5-chlorobenzene-1,3-dicarboxylic acid ester, the carboxyl group needs to undergo an esterification reaction. The commonly used method is to react with alcohols and acids in the presence of a catalyst.
In this reaction, methanol can be used as an alcohol reagent. The catalyst can choose protonic acids such as sulfuric acid. For specific operation, 5-chloro-isophthalic acid and excess methanol are placed in a reaction vessel, and an appropriate amount of sulfuric acid is added as a catalyst. Heat the reaction system to maintain the temperature in a suitable range, usually near the boiling point of methanol, to promote the esterification reaction.
During the reaction, the acid and the alcohol are dehydrated and condensed, and the carboxyl group is connected to the methoxy group to gradually form dimethyl 5-chlorobenzene-1,3-dicarboxylate. This reaction is a reversible reaction. In order to move the reaction in the direction of generating the product, measures such as removing the water generated by the reaction can be taken.
After the reaction reaches a certain degree, cool the reaction system. The product can be purified by subsequent separation and purification steps, such as reduced pressure distillation, recrystallization, etc., to obtain a pure dimethyl 5-chlorobenzene-1,3-dicarboxylate.
There are other methods, or 5-chloro-isophthalic acid can be activated first to enhance the carboxyl activity, and then reacted with methanol to achieve the purpose of synthesis. However, no matter what method, the reaction conditions need to be carefully controlled to obtain satisfactory yield and purity.
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Furthermore, the information platform of the chemical industry is also a way to explore prices. It often collects all kinds of information about the industry, including the price dynamics of various raw materials. There may be information about the price of "Dimethyl 5 - chlorobenzene - 1,3 - dicarboxylate", and there may be experts to analyze the causes and future trends of its price.
In addition, it is also a good law to communicate with the manufacturer of this product. The manufacturer knows its production cost and sets the price according to the market. Ask for the price, and you can get the approximate price of the factory. This is the basic price, or it can help to know the price range in the market circulation process.
However, if you want to get an accurate price, you must comprehensively consider multiple factors. If the purity of the product, the price of high purity is always high; if the supply and demand in the market is greater than the supply, the price will be higher, and the price will be lower; if the cost of production, raw materials, manpower, energy consumption, etc. changes, the price will also change; the cost of transportation, the distance and the mode of transportation are different, and the price will vary. Therefore, if you want to determine the market price of "Dimethyl 5 - chlorobenzene - 1,3 - dicarboxylate", you must search for information widely and consider carefully to obtain a more accurate price.
First word storage. This material should be stored in a cool, dry and well-ventilated place. Due to its chemical properties, if placed in a high temperature, humid place, or cause deterioration. High temperature can promote its chemical reaction, accelerate decomposition or polymerization, and damage its quality. Humid environment may cause reactions such as hydrolysis, which affects purity and performance. In addition, it should be kept away from fire and heat sources, because it may be flammable or may react violently with heat. In case of open flame or hot topic, there is a risk of fire and explosion. And it needs to be stored separately from oxidizing agents, reducing agents, etc., and mixed with materials of different chemical properties, which is prone to uncontrollable chemical reactions.
As for transportation, there are also many details. Transportation vehicles must ensure that they are in good condition and have fire and explosion-proof facilities. The loading and unloading process should be handled with care to avoid collisions and heavy pressure to prevent material leakage due to package damage. Once leaked, it will not only waste materials, pollute the environment, but also cause dangerous reactions due to contact with external substances. During transportation, drivers and escorts must pay close attention to the status of the goods, drive according to the specified route, and stay away from densely populated areas and important facilities. In case of emergencies, they can be properly disposed of in time to ensure transportation safety. In this way, it is possible to avoid risks and protect the quality and safety of 5-chlorobenzene-1,3-dicarboxylate dicarboxylate when storing and transporting it.

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