Linshang Chemical
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M-Cyanochlorobenzene
Linshang Chemical
|
HS Code |
805195 |
| Chemical Formula | C7H4ClN |
| Molar Mass | 137.57 g/mol |
| Appearance | Colorless to light yellow liquid or solid |
| Odor | Characteristic |
| Melting Point | 26 - 28 °C |
| Boiling Point | 232 - 234 °C |
| Density | 1.25 g/cm³ |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in many organic solvents like ethanol, ether |
| Flash Point | 102 °C |
| Vapor Pressure | Low at room temperature |
As an accredited M-Cyanochlorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of M - cyanochlorobenzene packaged in a sealed, corrosion - resistant plastic bottle. |
| Storage | M - cyanochlorobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat, flames, and oxidizing agents. Store it in tightly sealed containers to prevent leakage. Separate from incompatible substances. Adhere to proper labeling for easy identification and ensure compliance with safety regulations during storage. |
| Shipping | M - cyanochlorobenzene shipping requires strict compliance with chemical transportation regulations. It should be properly packaged in corrosion - resistant containers, labeled clearly, and transported by carriers licensed for hazardous chemicals. |
Competitive M-Cyanochlorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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As a leading M-Cyanochlorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of M-cyanochlorobenzene?
M-cyanochlorobenzene is one of the organic compounds. Its main use is crucial in the field of organic synthesis.
First, it can be used as a raw material for pharmaceutical synthesis. The preparation of many drugs depends on its participation. Through a series of chemical reactions, the specific structure of drug molecules can be constructed. For example, in the synthesis of some antibacterial and anti-inflammatory drugs, M-cyanochlorobenzene is an important starting material, laying the foundation for the formation of pharmaceutical active ingredients.
Second, it also plays an important role in the manufacture of pesticides. It can derive a variety of high-efficiency pesticide ingredients, which have significant control effects on crop diseases and pests, can effectively improve the yield and quality of crops, and protect the harvest of agriculture.
Third, in the field of dye synthesis, M-cyanochlorobenzene also plays an important role. It can be used as a key intermediate in the synthesis of specific color dyes, giving dyes unique colors and properties, and meeting the needs of color diversification in textile, printing and dyeing industries.
Fourth, in the field of materials science, through chemical reaction modification, it can be introduced into the structure of polymer materials to improve the physical and chemical properties of materials, such as enhancing the stability and heat resistance of materials, and expanding the application scenarios of materials.
In short, M-cyanochlorobenzene plays an important role in many fields of chemical industry, and has made great contributions to promoting the development of various industries.
First, it can be used as a raw material for pharmaceutical synthesis. The preparation of many drugs depends on its participation. Through a series of chemical reactions, the specific structure of drug molecules can be constructed. For example, in the synthesis of some antibacterial and anti-inflammatory drugs, M-cyanochlorobenzene is an important starting material, laying the foundation for the formation of pharmaceutical active ingredients.
Second, it also plays an important role in the manufacture of pesticides. It can derive a variety of high-efficiency pesticide ingredients, which have significant control effects on crop diseases and pests, can effectively improve the yield and quality of crops, and protect the harvest of agriculture.
Third, in the field of dye synthesis, M-cyanochlorobenzene also plays an important role. It can be used as a key intermediate in the synthesis of specific color dyes, giving dyes unique colors and properties, and meeting the needs of color diversification in textile, printing and dyeing industries.
Fourth, in the field of materials science, through chemical reaction modification, it can be introduced into the structure of polymer materials to improve the physical and chemical properties of materials, such as enhancing the stability and heat resistance of materials, and expanding the application scenarios of materials.
In short, M-cyanochlorobenzene plays an important role in many fields of chemical industry, and has made great contributions to promoting the development of various industries.
What are the physical properties of M-cyanochlorobenzene?
M-cyanochlorobenzene is also an organic compound. It has specific physical properties, let me describe it in detail for you.
First of all, its appearance, under room temperature and pressure, M-cyanochlorobenzene is often colorless to light yellow liquid, clear in appearance, with a certain fluidity. Its color is elegant, and it is also one of the characteristics of discrimination.
Melting point and boiling point. The melting point is about -20 ° C. At this temperature, the state of matter gradually changes from liquid to solid. The boiling point is between 230 ° C and 240 ° C. At this temperature, the liquid turns into a gaseous state. This characteristic is quite important in separation, purification and other processes.
Furthermore, in terms of density, its density is slightly higher than that of water, about 1.27g/cm ³. If it is co-located with water, it can be seen that it sinks to the bottom of the water, and this density difference is also one of its physical properties.
In terms of solubility, M-cyanochlorobenzene has little solubility in water and is almost insoluble. This is due to the difference between the hydrogen bond between water molecules and the molecular structure of M-cyanochlorobenzene. However, it has good solubility in organic solvents, such as ethanol, ether, benzene, etc., and can be miscible with various organic solvents. This property makes it widely used in organic synthesis and other fields.
In addition, M-cyanochlorobenzene has certain volatility, which can evaporate slowly in the air, and has a special odor. Although it is not pungent and unpleasant, it is also one end of its physical properties, which can help the senses to distinguish.
In summary, the physical properties of M-cyanochlorobenzene, such as appearance, melting point, density, solubility and volatility, have their own characteristics, which are of great significance in chemical research, industrial production and many other aspects. It is the basis for the cognition and application of this compound.
First of all, its appearance, under room temperature and pressure, M-cyanochlorobenzene is often colorless to light yellow liquid, clear in appearance, with a certain fluidity. Its color is elegant, and it is also one of the characteristics of discrimination.
Melting point and boiling point. The melting point is about -20 ° C. At this temperature, the state of matter gradually changes from liquid to solid. The boiling point is between 230 ° C and 240 ° C. At this temperature, the liquid turns into a gaseous state. This characteristic is quite important in separation, purification and other processes.
Furthermore, in terms of density, its density is slightly higher than that of water, about 1.27g/cm ³. If it is co-located with water, it can be seen that it sinks to the bottom of the water, and this density difference is also one of its physical properties.
In terms of solubility, M-cyanochlorobenzene has little solubility in water and is almost insoluble. This is due to the difference between the hydrogen bond between water molecules and the molecular structure of M-cyanochlorobenzene. However, it has good solubility in organic solvents, such as ethanol, ether, benzene, etc., and can be miscible with various organic solvents. This property makes it widely used in organic synthesis and other fields.
In addition, M-cyanochlorobenzene has certain volatility, which can evaporate slowly in the air, and has a special odor. Although it is not pungent and unpleasant, it is also one end of its physical properties, which can help the senses to distinguish.
In summary, the physical properties of M-cyanochlorobenzene, such as appearance, melting point, density, solubility and volatility, have their own characteristics, which are of great significance in chemical research, industrial production and many other aspects. It is the basis for the cognition and application of this compound.
What is the chemistry of M-cyanochlorobenzene?
M-cyanochlorobenzene is also an organic compound. It is active and has the characteristics of cyanyl and chlorine atoms.
Cyanyl has strong electron-absorbing properties, which can reduce the electron cloud density of the benzene ring and weaken the activity of the electrophilic substitution reaction of the benzene ring. However, in the nucleophilic substitution reaction, the cyanyl group can increase the activity of the neighboring and para-position chlorine atoms due to its own electron-withdrawing properties, and is easily replaced by the attack of nucleophilic reagents.
The chlorine atom on the benzene ring is an ortho-and para-position locator. Although it has an electron-withdrawing induction effect, it also has a electron-giving conjugation effect. During the electrophilic substitution reaction, the reaction can However, due to its high electronegativity, the electron cloud density of the benzene ring decreases, making the electrophilic substitution reaction more difficult than benzene.
M-cyanochlorobenzene can react with many reagents. For example, with nucleophiles, such as sodium alcohols, amines, etc., under suitable conditions, chlorine atoms can be replaced to obtain corresponding replacement products. Reacting with metal reagents, such as magnesium, lithium, etc., can prepare organometallic compounds, which can be used to synthesize complex organic molecules.
In oxidation reactions, cyano groups can be oxidized to carboxyl groups and other groups; in reduction reactions, cyano groups can be reduced to amino groups or imino groups. Its physical properties can not be ignored, mostly solid at room temperature, with a certain melting point and boiling point, slightly soluble in water, easily soluble in organic solvents, such as ethanol, ether, dichloromethane, etc. Due to its special chemical properties, it is widely used in medicine, pesticides, dyes and other fields.
Cyanyl has strong electron-absorbing properties, which can reduce the electron cloud density of the benzene ring and weaken the activity of the electrophilic substitution reaction of the benzene ring. However, in the nucleophilic substitution reaction, the cyanyl group can increase the activity of the neighboring and para-position chlorine atoms due to its own electron-withdrawing properties, and is easily replaced by the attack of nucleophilic reagents.
The chlorine atom on the benzene ring is an ortho-and para-position locator. Although it has an electron-withdrawing induction effect, it also has a electron-giving conjugation effect. During the electrophilic substitution reaction, the reaction can However, due to its high electronegativity, the electron cloud density of the benzene ring decreases, making the electrophilic substitution reaction more difficult than benzene.
M-cyanochlorobenzene can react with many reagents. For example, with nucleophiles, such as sodium alcohols, amines, etc., under suitable conditions, chlorine atoms can be replaced to obtain corresponding replacement products. Reacting with metal reagents, such as magnesium, lithium, etc., can prepare organometallic compounds, which can be used to synthesize complex organic molecules.
In oxidation reactions, cyano groups can be oxidized to carboxyl groups and other groups; in reduction reactions, cyano groups can be reduced to amino groups or imino groups. Its physical properties can not be ignored, mostly solid at room temperature, with a certain melting point and boiling point, slightly soluble in water, easily soluble in organic solvents, such as ethanol, ether, dichloromethane, etc. Due to its special chemical properties, it is widely used in medicine, pesticides, dyes and other fields.
What is the production process of M-cyanochlorobenzene?
M-cyanochlorobenzene is also an organic compound. The preparation process of M-cyanochlorobenzene in ancient times may be different from that of today, and the general method is described in detail today.
In the past, M-cyanochlorobenzene was prepared, often with m-chloroaniline as the starting material. First, it is reacted with sodium nitrite and hydrochloric acid to obtain m-chlorodiazophenzene hydrochloride. This reaction needs to be in a low temperature environment, about 0-5 ° C, to ensure the stability of the reaction and the purity of the product. M-cyanochlorobenzene hydrochloride is very active, and then interacts with a mixture of cuprous cyanide and potassium cyanide to obtain M-cyanochlorobenzene. However, the cuprous cyanide and potassium cyanide used in this method are highly toxic, careless operation, easy to cause trouble, and complicated post-reaction treatment, and the resulting waste is also harmful to the environment.
Today's process uses m-chlorotoluene as raw material. First, m-chlorotoluene is reacted with chlorine under the conditions of light or initiator to obtain m-chlorobenzyl chloride. This step of the reaction conditions is mild, and the rate of chlorine gas penetration and the intensity of light are all key factors. M-cyanobenzyl chloride is reacted with sodium cyanide in an appropriate solvent, such as N, N-dimethylformamide, to obtain M-cyanobenzene. Compared with the old method, the raw materials used in this process are slightly less toxic, the operation is relatively simple, and the yield is relatively considerable, which is more favored by today's industrial production. During the preparation process, the temperature, time, and ratio of reactants at each step need to be carefully adjusted to obtain high-quality M-cyanochlorobenzene products.
In the past, M-cyanochlorobenzene was prepared, often with m-chloroaniline as the starting material. First, it is reacted with sodium nitrite and hydrochloric acid to obtain m-chlorodiazophenzene hydrochloride. This reaction needs to be in a low temperature environment, about 0-5 ° C, to ensure the stability of the reaction and the purity of the product. M-cyanochlorobenzene hydrochloride is very active, and then interacts with a mixture of cuprous cyanide and potassium cyanide to obtain M-cyanochlorobenzene. However, the cuprous cyanide and potassium cyanide used in this method are highly toxic, careless operation, easy to cause trouble, and complicated post-reaction treatment, and the resulting waste is also harmful to the environment.
Today's process uses m-chlorotoluene as raw material. First, m-chlorotoluene is reacted with chlorine under the conditions of light or initiator to obtain m-chlorobenzyl chloride. This step of the reaction conditions is mild, and the rate of chlorine gas penetration and the intensity of light are all key factors. M-cyanobenzyl chloride is reacted with sodium cyanide in an appropriate solvent, such as N, N-dimethylformamide, to obtain M-cyanobenzene. Compared with the old method, the raw materials used in this process are slightly less toxic, the operation is relatively simple, and the yield is relatively considerable, which is more favored by today's industrial production. During the preparation process, the temperature, time, and ratio of reactants at each step need to be carefully adjusted to obtain high-quality M-cyanochlorobenzene products.
What are the precautions in storage and transportation of M-cyanochlorobenzene?
M-Cyanochlorobenzene is an organic compound. When storing and transporting, all precautions should not be ignored.
The first storage place. Must choose a cool, dry and well-ventilated place, away from fire and heat sources. Because of its flammability, it can cause combustion in case of open flames and hot topics, so fire prevention is of paramount importance. The temperature of the warehouse should be controlled within an appropriate range to prevent its chemical properties from changing due to excessive temperature and causing danger.
Furthermore, when storing, it must be stored in separate stores with oxidizing agents, acids, alkalis, etc., and must not be mixed. Due to its active chemical properties, contact with the above substances is prone to chemical reactions, or cause fires, explosions and other disasters. And the storage area should be equipped with suitable containment materials, so that in case of leakage, it can be collected and disposed of quickly, so as not to cause greater harm due to its spread.
As for transportation, caution is also required. The transportation vehicle must ensure that the vehicle is in good condition and has corresponding safety facilities. The loading and unloading process must be handled with care, and it should not be bumped or pressed to avoid material leakage due to damaged packaging. During transportation, drivers and passengers should pay close attention to the condition of the goods to avoid high temperature, sun and rain. If passing through densely populated areas or important areas, it is necessary to be extra cautious and follow the designated route to ensure the safety of the whole transportation process. In this way, M-cyanochlorobenzene should not cause harm during storage and transportation, and protect the safety of people, objects and the environment.
The first storage place. Must choose a cool, dry and well-ventilated place, away from fire and heat sources. Because of its flammability, it can cause combustion in case of open flames and hot topics, so fire prevention is of paramount importance. The temperature of the warehouse should be controlled within an appropriate range to prevent its chemical properties from changing due to excessive temperature and causing danger.
Furthermore, when storing, it must be stored in separate stores with oxidizing agents, acids, alkalis, etc., and must not be mixed. Due to its active chemical properties, contact with the above substances is prone to chemical reactions, or cause fires, explosions and other disasters. And the storage area should be equipped with suitable containment materials, so that in case of leakage, it can be collected and disposed of quickly, so as not to cause greater harm due to its spread.
As for transportation, caution is also required. The transportation vehicle must ensure that the vehicle is in good condition and has corresponding safety facilities. The loading and unloading process must be handled with care, and it should not be bumped or pressed to avoid material leakage due to damaged packaging. During transportation, drivers and passengers should pay close attention to the condition of the goods to avoid high temperature, sun and rain. If passing through densely populated areas or important areas, it is necessary to be extra cautious and follow the designated route to ensure the safety of the whole transportation process. In this way, M-cyanochlorobenzene should not cause harm during storage and transportation, and protect the safety of people, objects and the environment.
What are the main uses of M-cyanochlorobenzene?
M-cyanochlorobenzene is a class of organic compounds. Its main uses cover a wide range of fields.
In the synthesis of medicine, this compound is often a key intermediary. The preparation of medicine, like a craftsman, requires many fine raw materials. M-cyanochlorobenzene can be combined with other compounds through specific chemical reactions to generate drugs with therapeutic effects. For example, for some drugs targeting specific diseases, the synthesis path relies on this as the cornerstone of the beginning, and after many reaction steps, it eventually becomes a good medicine to heal the pain.
In the process of pesticide creation, M-cyanochlorobenzene is also crucial. The ability of pesticides lies in protecting crops and preventing the invasion of pests and diseases. With this as a raw material, efficient and targeted pesticides can be made. Its structural characteristics enable the prepared pesticides to precisely act on the physiological mechanisms of pests or pathogens, inhibit their reproduction, inhibit their growth, maintain the flourishing of crops, and protect the harvest of farmland.
Furthermore, in the field of materials science, this compound is also promising. The development of new materials requires finding suitable ingredients. M-cyanochlorobenzene can participate in the synthesis process of materials, giving materials special properties, such as improving the stability, conductivity or optical properties of materials. Or used to prepare special polymer materials, showing unique advantages in electronic devices, optical instruments, etc.
M-cyanochlorobenzene is an indispensable element in many fields such as medicine, pesticides and materials science due to its unique chemical properties. It plays a key role in industrial production and scientific research.
In the synthesis of medicine, this compound is often a key intermediary. The preparation of medicine, like a craftsman, requires many fine raw materials. M-cyanochlorobenzene can be combined with other compounds through specific chemical reactions to generate drugs with therapeutic effects. For example, for some drugs targeting specific diseases, the synthesis path relies on this as the cornerstone of the beginning, and after many reaction steps, it eventually becomes a good medicine to heal the pain.
In the process of pesticide creation, M-cyanochlorobenzene is also crucial. The ability of pesticides lies in protecting crops and preventing the invasion of pests and diseases. With this as a raw material, efficient and targeted pesticides can be made. Its structural characteristics enable the prepared pesticides to precisely act on the physiological mechanisms of pests or pathogens, inhibit their reproduction, inhibit their growth, maintain the flourishing of crops, and protect the harvest of farmland.
Furthermore, in the field of materials science, this compound is also promising. The development of new materials requires finding suitable ingredients. M-cyanochlorobenzene can participate in the synthesis process of materials, giving materials special properties, such as improving the stability, conductivity or optical properties of materials. Or used to prepare special polymer materials, showing unique advantages in electronic devices, optical instruments, etc.
M-cyanochlorobenzene is an indispensable element in many fields such as medicine, pesticides and materials science due to its unique chemical properties. It plays a key role in industrial production and scientific research.
What are the physical properties of M-cyanochlorobenzene?
M-cyanochlorobenzene is also an organic compound. Its physical properties are particularly important and are related to many chemical applications.
First of all, its appearance, under room temperature and pressure, is often colorless to light yellow liquid, and it is clear when viewed. If you look closely, you can see that it flows like oil, with uniform texture and no impurities mixed in it.
As for the melting point, it is about -20 ° C to -10 ° C. This low temperature melting point makes the substance exist as a liquid at room temperature. The boiling point is within the range of 230 ° C to 240 ° C, and a higher temperature is required to make it boil and vaporize. The density of
is about 1.2-1.3g/cm ³, which is heavier than water. If it is co-located with water, it will sink to the bottom of the water. Its solubility also has characteristics, and it is extremely difficult to dissolve in water. It is difficult to form a homogeneous phase because of the significant difference between its molecular structure and the polarity of water molecules. However, in organic solvents, such as ethanol, ether, benzene, etc., it is quite soluble. Because the molecular structure of organic solvents is similar to that of M-cyanochlorobenzene, the two are mutually soluble according to the principle of similar compatibility.
Furthermore, its volatility is weak, and it is difficult to disperse quickly even if placed in air. And it has a certain smell, but it is not a pungent and unpleasant smell, but a slightly special aromatic aroma, but its smell still needs to be treated with caution, because the substance has certain toxicity.
The physical properties of M-cyanochlorobenzene are of great significance in many fields such as organic synthesis, medicine and chemical industry, and are the key information that chemical practitioners must know.
First of all, its appearance, under room temperature and pressure, is often colorless to light yellow liquid, and it is clear when viewed. If you look closely, you can see that it flows like oil, with uniform texture and no impurities mixed in it.
As for the melting point, it is about -20 ° C to -10 ° C. This low temperature melting point makes the substance exist as a liquid at room temperature. The boiling point is within the range of 230 ° C to 240 ° C, and a higher temperature is required to make it boil and vaporize. The density of
is about 1.2-1.3g/cm ³, which is heavier than water. If it is co-located with water, it will sink to the bottom of the water. Its solubility also has characteristics, and it is extremely difficult to dissolve in water. It is difficult to form a homogeneous phase because of the significant difference between its molecular structure and the polarity of water molecules. However, in organic solvents, such as ethanol, ether, benzene, etc., it is quite soluble. Because the molecular structure of organic solvents is similar to that of M-cyanochlorobenzene, the two are mutually soluble according to the principle of similar compatibility.
Furthermore, its volatility is weak, and it is difficult to disperse quickly even if placed in air. And it has a certain smell, but it is not a pungent and unpleasant smell, but a slightly special aromatic aroma, but its smell still needs to be treated with caution, because the substance has certain toxicity.
The physical properties of M-cyanochlorobenzene are of great significance in many fields such as organic synthesis, medicine and chemical industry, and are the key information that chemical practitioners must know.
What is the chemistry of M-cyanochlorobenzene?
M-cyanochlorobenzene is one of the organic compounds. It has unique chemical properties and is worthy of in-depth study.
When it comes to chemical activity, the cyano group (-CN) and the chlorine atom (-Cl) in this compound endow it with activity. Cyanyl has strong electron absorption, which can reduce the electron cloud density of the benzene ring, reduce the electrophilic substitution activity of the benzene ring, and reduce the electron cloud density of the ortho and para-sites more than that of the meta-site. Although the chlorine atom is also an electron-absorbing group, when it is connected to the benzene ring, it can conjugate with the benzene ring because of its solitary pair-electrons, which can increase the electron cloud density of the benzene ring to a certain extent and have a certain impact on the electrophilic substitution reaction. The coexistence of the two makes the reactivity of M-cyanochlorobenzene unique.
In the nucleophilic substitution reaction, the chlorine atom can be replaced by the nucleophilic reagent. Cyanogen genes have strong polarity and can participate in many reactions, such as addition to nucleophilic reagents, or hydrolysis under specific conditions.
Furthermore, the physical properties of M-cyanochlorobenzene are also related to its chemical properties. Its melting point, boiling point, etc. are affected by the intermolecular forces. The presence of cyano and chlorine atoms changes the molecular polarity, which in turn affects the intermolecular forces.
Because of its cyanide group, it has certain toxicity. When using and handling, it is necessary to be careful and follow the corresponding safety procedures to avoid harming the human body and the environment. In conclusion, M-cyanochlorobenzene has rich and unique chemical properties and is widely used in organic synthesis, but its potential harm should not be underestimated.
When it comes to chemical activity, the cyano group (-CN) and the chlorine atom (-Cl) in this compound endow it with activity. Cyanyl has strong electron absorption, which can reduce the electron cloud density of the benzene ring, reduce the electrophilic substitution activity of the benzene ring, and reduce the electron cloud density of the ortho and para-sites more than that of the meta-site. Although the chlorine atom is also an electron-absorbing group, when it is connected to the benzene ring, it can conjugate with the benzene ring because of its solitary pair-electrons, which can increase the electron cloud density of the benzene ring to a certain extent and have a certain impact on the electrophilic substitution reaction. The coexistence of the two makes the reactivity of M-cyanochlorobenzene unique.
In the nucleophilic substitution reaction, the chlorine atom can be replaced by the nucleophilic reagent. Cyanogen genes have strong polarity and can participate in many reactions, such as addition to nucleophilic reagents, or hydrolysis under specific conditions.
Furthermore, the physical properties of M-cyanochlorobenzene are also related to its chemical properties. Its melting point, boiling point, etc. are affected by the intermolecular forces. The presence of cyano and chlorine atoms changes the molecular polarity, which in turn affects the intermolecular forces.
Because of its cyanide group, it has certain toxicity. When using and handling, it is necessary to be careful and follow the corresponding safety procedures to avoid harming the human body and the environment. In conclusion, M-cyanochlorobenzene has rich and unique chemical properties and is widely used in organic synthesis, but its potential harm should not be underestimated.
What is the production process of M-cyanochlorobenzene?
M-cyanochlorobenzene is an organic compound. The method of its preparation is often based on the magic of organic synthesis in the past.
In the past, M-cyanochlorobenzene was prepared, mostly m-chloronitrobenzene as the starting material. First, m-chloronitrobenzene was reduced by iron filings and hydrochloric acid as a medium, so that the nitro group was reduced to an amino group to obtain m-chloroaniline. In this process, the iron filings interact with hydrochloric acid to produce new hydrogen, and then the nitro group is reduced.
The obtained m-chloroaniline is reacted with sodium nitrite and hydrochloric acid. At low temperature, m-chloroaniline interacts with sodium nitrite and hydrochloric acid, and the amino group becomes a diazonium salt. The reaction is delicate and requires strict temperature control to prevent the decomposition of diazonium salts.
The diazonium salt is formed, but it is mixed with the solution of cuprous cyanide and potassium cyanide to perform the Sandmeyer Reaction. In this reaction, the diazonium group is replaced by the cyanyl group, and the final product is M-cyanochlorobenzene. This reaction is catalyzed by cuprous cyanide, so that the diazonium group is cleverly converted to the cyano group.
There is another way, or starting from m-chlorobenzaldehyde, it is reacted by oximization to obtain m-chlorobenzene oxime, and then converted into M-cyanochlorobenzene by the action of a dehydrating agent. When oximization, m-chlorobenzaldehyde reacts with hydroxylam In the process of dehydration, the oxime group is dehydrated by the power of the dehydrating agent to remove a molecule of water and turn it into a cyano group.
The various processes for preparing M-cyanochlorobenzene rely on the wisdom of organic synthesis in the past. After multiple steps of exquisite reaction, this compound is also obtained.
In the past, M-cyanochlorobenzene was prepared, mostly m-chloronitrobenzene as the starting material. First, m-chloronitrobenzene was reduced by iron filings and hydrochloric acid as a medium, so that the nitro group was reduced to an amino group to obtain m-chloroaniline. In this process, the iron filings interact with hydrochloric acid to produce new hydrogen, and then the nitro group is reduced.
The obtained m-chloroaniline is reacted with sodium nitrite and hydrochloric acid. At low temperature, m-chloroaniline interacts with sodium nitrite and hydrochloric acid, and the amino group becomes a diazonium salt. The reaction is delicate and requires strict temperature control to prevent the decomposition of diazonium salts.
The diazonium salt is formed, but it is mixed with the solution of cuprous cyanide and potassium cyanide to perform the Sandmeyer Reaction. In this reaction, the diazonium group is replaced by the cyanyl group, and the final product is M-cyanochlorobenzene. This reaction is catalyzed by cuprous cyanide, so that the diazonium group is cleverly converted to the cyano group.
There is another way, or starting from m-chlorobenzaldehyde, it is reacted by oximization to obtain m-chlorobenzene oxime, and then converted into M-cyanochlorobenzene by the action of a dehydrating agent. When oximization, m-chlorobenzaldehyde reacts with hydroxylam In the process of dehydration, the oxime group is dehydrated by the power of the dehydrating agent to remove a molecule of water and turn it into a cyano group.
The various processes for preparing M-cyanochlorobenzene rely on the wisdom of organic synthesis in the past. After multiple steps of exquisite reaction, this compound is also obtained.
M-cyanochlorobenzene what are the precautions during use
M-Cyanochlorobenzene is an organic compound. During use, many precautions should be kept in mind.
First, it is related to safety protection. This substance is toxic and irritating, and appropriate protective equipment must be worn when exposed. If you wear protective gloves to avoid skin contact with it, causing allergies or other damage; wear protective glasses to protect your eyes from damage; you need protective clothing to protect your body in all directions. It is also essential to operate in a well-ventilated place. If it is in a closed space, its volatile gas can cause respiratory discomfort or even poisoning.
Second, pay attention to storage conditions. Store in a cool, dry and ventilated place, away from fire and heat sources. Because it may cause combustion and explosion when exposed to open flames and hot topics, it will also react violently when in contact with oxidants. And it needs to be stored separately from edible chemicals, oxidants, etc., and should not be mixed with storage to prevent dangerous interaction.
Third, the operating specifications should not be ignored. When taking it, the action should be stable and accurate to avoid spillage. If there is a spill, quickly clean it up according to relevant procedures. If it is absorbed with inert materials such as sand and vermiculite, it should be properly handled. Do not dump it at will to avoid polluting the environment. During the operation, do not eat, smoke, and wash your hands after operation.
Fourth, know emergency treatment. If you accidentally come into contact with the skin, rinse quickly with a large amount of flowing water; when you enter the eyes, immediately lift the eyelids, rinse with flowing water or normal saline and seek medical attention. If you inhale, leave the scene to the fresh air quickly. If you have breathing difficulties, give oxygen, and if you stop breathing, perform artificial respiration and seek medical attention immediately. In the event of a fire, according to its characteristics, use a suitable extinguishing agent to extinguish the fire, such as dry powder, carbon dioxide, etc.
First, it is related to safety protection. This substance is toxic and irritating, and appropriate protective equipment must be worn when exposed. If you wear protective gloves to avoid skin contact with it, causing allergies or other damage; wear protective glasses to protect your eyes from damage; you need protective clothing to protect your body in all directions. It is also essential to operate in a well-ventilated place. If it is in a closed space, its volatile gas can cause respiratory discomfort or even poisoning.
Second, pay attention to storage conditions. Store in a cool, dry and ventilated place, away from fire and heat sources. Because it may cause combustion and explosion when exposed to open flames and hot topics, it will also react violently when in contact with oxidants. And it needs to be stored separately from edible chemicals, oxidants, etc., and should not be mixed with storage to prevent dangerous interaction.
Third, the operating specifications should not be ignored. When taking it, the action should be stable and accurate to avoid spillage. If there is a spill, quickly clean it up according to relevant procedures. If it is absorbed with inert materials such as sand and vermiculite, it should be properly handled. Do not dump it at will to avoid polluting the environment. During the operation, do not eat, smoke, and wash your hands after operation.
Fourth, know emergency treatment. If you accidentally come into contact with the skin, rinse quickly with a large amount of flowing water; when you enter the eyes, immediately lift the eyelids, rinse with flowing water or normal saline and seek medical attention. If you inhale, leave the scene to the fresh air quickly. If you have breathing difficulties, give oxygen, and if you stop breathing, perform artificial respiration and seek medical attention immediately. In the event of a fire, according to its characteristics, use a suitable extinguishing agent to extinguish the fire, such as dry powder, carbon dioxide, etc.
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