Methyl 3-Amino-4-Chlorobenzene

Linshang Chemical

Specifications

HS Code

309053

Chemical Formula C8H8ClNO2
Molar Mass 187.608 g/mol
Appearance Solid

As an accredited Methyl 3-Amino-4-Chlorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1 kg of Methyl 3 - amino - 4 - chlorobenzene packaged in airtight plastic bags.
Storage **Storage for Methyl 3 - amino - 4 - chlorobenzene**: Store this chemical in a cool, dry, well - ventilated area away from sources of ignition and heat. Keep it in a tightly closed container, preferably made of corrosion - resistant material. Avoid storage near oxidizing agents. Due to its potential hazards, ensure the storage location is restricted to authorized personnel only.
Shipping Methyl 3 - amino - 4 - chlorobenzene should be shipped in well - sealed, corrosion - resistant containers. It must comply with relevant hazardous chemical shipping regulations, ensuring proper labeling and documentation during transit.
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Methyl 3-Amino-4-Chlorobenzene Methyl 3-Amino-4-Chlorobenzene
General Information
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Frequently Asked Questions

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What are the main uses of Methyl 3 - amino - 4 - chlorobenzene
Methyl-3-amino-4-chlorobenzene, this is an organic compound. It has a wide range of uses and is of great value in many fields.
In the field of medicine, it is often used as a key intermediate. Due to specific amino and chlorine atoms, it can be converted into compounds with specific pharmacological activities through a series of chemical reactions. Or it can be used to develop antibacterial drugs, by precisely designing molecular structures, to improve the inhibition or killing ability of drugs against specific bacteria; or it can play a role in the development of anti-tumor drugs, helping to build drug molecules that target tumor cells.
In the field of pesticides, it is also an important raw material. After rational modification and synthesis, high-efficiency insecticides, fungicides, etc. can be prepared. Its structural characteristics may endow pesticides with unique mechanisms of action, enhance the control effect against pests and bacteria, and reduce the adverse impact on the environment.
In the field of materials science, methyl-3-amino-4-chlorobenzene is also used. It can participate in the synthesis of polymer materials with special properties, such as conductive polymers, optical materials, etc. Because of its special functional groups, it can introduce unique electrical and optical properties to materials and broaden the application range of materials. With its unique chemical structure, methyl-3-amino-4-chlorobenzene plays an important role in many fields such as medicine, pesticides, and materials science, providing indispensable support for the development of related industries.
What are the physical properties of Methyl 3 - amino - 4 - chlorobenzene
The physical properties of methyl-3-amino-4-chlorobenzene are as follows.
In appearance, this substance is often in the form of a colorless to light yellow liquid or solid, depending on conditions such as ambient temperature. Looking at its color, it is due to the interaction of atoms in the molecular structure that it presents such a color under visible light. It has a certain smell, but the exact description of the smell needs to be smelled to be accurate. It is roughly a specific aromatic smell. The root of this smell is also closely related to the molecular structure, and the specific atomic arrangement causes it to emit a unique taste.
When it comes to the melting point, if it is a solid form, it has a specific melting point range, which depends on the magnitude of the intermolecular force. The stronger the intermolecular force, the higher the melting point; vice versa. At the melting point, a substance changes from a solid state to a liquid state, and the thermal motion of the molecules intensifies, overcoming the constraints of lattice energy.
In terms of boiling point, when it is heated, the kinetic energy of the molecules continues to increase. When it reaches the boiling point, a large number of molecules break free from the liquid phase and transform into a gaseous state. The level of boiling point is also related to the intermolecular force and the relative molecular mass. The greater the relative molecular mass, the stronger the intermolecular force and the higher the boiling point.
Density is also one of the important physical properties. Its density value reflects the mass of the substance per unit volume and depends on the degree of tight packing of molecules and the relative molecular mass. The closer the molecular packing, the greater the relative molecular mass, the higher the density.
In terms of solubility, this substance may have a certain solubility in organic solvents, such as ethanol, ether, etc. Due to the principle of similarity and miscibility, its molecular structure is similar to that of organic solvents, and it can interact with each other and dissolve in a certain proportion; in water, the solubility may be limited, because the polarity of water is different from the polarity of the substance molecule, and the interaction force is weak.
In addition, its refractive index is also an inherent physical property. The refractive index reflects the degree to which the direction of light propagates in the substance changes. It is related to the molecular structure and density of the substance and can be used as the basis for identifying the substance or measuring its purity. This is the general physical properties of methyl-3-amino-4-chlorobenzene.
Methyl 3 - amino - 4 - chlorobenzene chemical properties
Methyl-3-amino-4-chlorobenzene is one of the organic compounds. It has many unique chemical properties.
is the first to bear the brunt, and the presence of amino groups endows this compound with alkalinity. Because amino nitrogen atoms contain lone pairs of electrons, they can accept protons and can form salts in acidic media. For example, in the case of hydrochloric acid, amino groups can combine with hydrogen ions to form corresponding ammonium salts. This property makes them uniquely soluble and reactive in solution under specific conditions.
Furthermore, chlorine atoms add nucleophilic substitution activity to the compound. Chlorine atoms, as a good leaving group, are easily replaced when attacked by nucleophiles. For example, when reacting with sodium alcohol, chlorine atoms can be replaced by alkoxy groups to form corresponding ether compounds. This reaction is an important method for building chemical bonds such as carbon-oxygen bonds in organic synthesis.
In addition, methyl groups, as a power supply group, can affect the electron cloud density of the benzene ring. It can increase the electron cloud density of the ortho and para-sites of the benzene ring, making the benzene ring more prone to electrophilic substitution reactions. For example, in electrophilic substitution reactions such as halogenation, nitrification, and sulfonation, the localization effect of methyl groups makes the reaction more inclined to proceed at the ortho and para-sites of the benzene ring, and then to synthesize derivatives with specific substitution positions.
From a redox perspective, if the compound encounters a strong oxidizing agent, the amino group may be ox The nitrogen atom in the amino group is in a lower oxidation state and has certain reductivity. It can be oxidized to higher oxidation products such as nitroso and nitro groups. This oxidation process will significantly change the structure and properties of the compound.
In short, methyl-3-amino-4-chlorobenzene has rich and diverse chemical properties and can act as a key intermediate in the field of organic synthesis for the preparation of various organic compounds with specific functions.
Methyl 3 - amino - 4 - chlorobenzene
The method of preparing methyl 3-amino-4-chlorobenzene is quite complicated, and it needs to be operated according to fine steps and suitable conditions. The common preparation methods are as follows:
Starting material, p-chlorotoluene is often selected. First, p-chlorotoluene is nitrified. In this step, a mixed acid of sulfuric acid and nitric acid is used as a reaction reagent to control the appropriate temperature and reaction time. Usually, the temperature is about 30-50 degrees Celsius, and the molar ratio of nitric acid to p-chlorotoluene needs to be precisely prepared, about 1.2-1.5:1. After this reaction, 3-nitro-4-chlorotoluene can be obtained, and this product is an important intermediate of the reaction.
Next, 3-nitro-4-chlorotoluene is reduced. The reduction method usually uses iron powder and hydrochloric acid as the reduction system, and the catalytic hydrogenation method can also be used. If iron powder and hydrochloric acid are used, the mass ratio of iron powder to 3-nitro-4-chlorotoluene is about 3-5:1, the concentration of hydrochloric acid is about 20% - 30%, and the reaction temperature is controlled at 80-100 degrees Celsius. After reduction, the nitro group is converted into an amino group, and methyl 3-amino-4-chlorobenzene is obtained.
Or select methyl 3-amino-4-chlorobenzoate as the starting material and prepare the target product through a specific decarboxylation reaction. This reaction requires suitable catalysts and reaction conditions, such as copper salts as catalysts, carried out under high temperature and inert gas protection.
Preparation of methyl 3-amino-4-chlorobenzene requires strict control of reaction conditions, including temperature, reagent ratio, reaction time, etc., and the product needs to be purified to obtain a high-purity product.
Methyl 3 - amino - 4 - chlorobenzene in the use of what are the precautions
Methyl-3-amino-4-chlorobenzene is a commonly used chemical substance. When using it, many matters must be paid attention to.
First, it is related to safety protection. This substance may be toxic and irritating. When operating, be sure to wear protective clothing, goggles and gloves to prevent skin contact and eye contamination. If you accidentally touch it, rinse with plenty of water immediately. If the situation is serious, seek medical attention immediately. At the same time, operate in a well-ventilated place to avoid inhaling its volatile gas to prevent respiratory tract irritation. When necessary, wear a gas mask.
Second, it is related to storage conditions. It should be placed in a cool, dry and ventilated place, away from fire and heat sources, and protected from direct sunlight. Due to its active chemical nature, it needs to be stored separately from oxidants, acids, alkalis, etc., and must not be mixed to avoid chemical reactions and lead to danger.
Third, it is related to the operation specification. During use, strictly follow the operation procedures and precisely control the reaction conditions, such as temperature, pressure, reaction time, etc. Due to the slight deviation of the reaction conditions, it may affect the quality of the product, or even cause safety accidents. After the operation is completed, properly dispose of the remaining materials and waste, and must not be discarded at will to avoid polluting the environment.
Fourth, it is related to emergency disposal. The workplace should be equipped with the corresponding variety and quantity of fire fighting equipment and leakage emergency treatment equipment. In the event of a leak, quickly evacuate the personnel from the contaminated area of the leak to the safe area, isolate them, and strictly restrict access. Emergency personnel must wear protective equipment, do not let the leak come into contact with combustible substances, and use appropriate methods to collect, clean up and deal with according to the leakage situation.