Linshang Chemical
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N-(2,3-Dichloropropyl)-4-Bromobenzenesulfonamide
Linshang Chemical
|
HS Code |
871619 |
| Chemical Formula | C9H9BrCl2NO3S |
| Molecular Weight | 346.945 g/mol |
| Physical State | Solid (predicted based on similar compounds) |
| Solubility In Water | Low (due to non - polar benzene and sulfonamide groups) |
| Solubility In Organic Solvents | Soluble in common organic solvents like chloroform, dichloromethane (due to its organic nature) |
| Vapor Pressure | Low (predicted as it's likely a solid at room temp) |
As an accredited N-(2,3-Dichloropropyl)-4-Bromobenzenesulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of N-(2,3 - dichloropropyl)-4 - bromobenzenesulfonamide in sealed chemical - grade bags. |
| Storage | Store N-(2,3 - dichloropropyl)-4 - bromobenzenesulfonamide in a cool, dry, well - ventilated area, away from heat sources and direct sunlight. Keep it in a tightly sealed container to prevent moisture absorption and contamination. Store separately from incompatible substances, such as oxidizing agents and strong acids, to avoid potential chemical reactions. |
| Shipping | Ship N-(2,3 - dichloropropyl)-4 - bromobenzenesulfonamide in accordance with chemical shipping regulations. Use appropriate packaging to prevent spills and ensure safe transport, handling it as a potentially hazardous chemical. |
Competitive N-(2,3-Dichloropropyl)-4-Bromobenzenesulfonamide prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
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As a leading N-(2,3-Dichloropropyl)-4-Bromobenzenesulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the chemical properties of N- (2,3-dichloropropyl) -4-bromobenzenesulfonamide?
N- (2,3 -dihydroxypropyl) -4 -bromobenzaldehyde is an organic compound with unique chemical properties.
In this compound, the benzene ring endows it with certain stability and conjugated system characteristics. The bromine atom attached to the benzene ring, because the electronegativity of bromine is greater than that of carbon, causes the electron cloud to bias towards the bromine atom, which reduces the electron cloud density of the benzene ring, and the electrophilic substitution reaction activity is changed compared with the unsubstituted benzene ring. And the bromine atom can participate in nucleophilic substitution and other reactions, which is an important reaction check point. The existence of
aldehyde group (-CHO) makes the compound have typical aldehyde chemical properties. The aldehyde group has high reactivity and can undergo oxidation reactions. For example, under the action of appropriate oxidizing agents, it can be oxidized to carboxyl groups (-COOH); it can also occur reduction reactions, which can be reduced to alcohol hydroxyl groups (-CH 2O OH). At the same time, aldehyde groups can participate in nucleophilic addition reactions, such as addition reactions with compounds containing active hydrogen, such as alcohols and amines, to generate acetals, Schiff bases and other products.
2,3-Dihydroxypropyl is connected to the benzene ring, and two hydroxyl groups (-OH) can form intramolecular or intermolecular hydrogen bonds. Intramolecular hydrogen bonds can affect the physical properties of compounds, such as melting point and boiling point; intermolecular hydrogen bonds can enhance intermolecular forces, which also affect their solubility and other properties. Hydroxyl groups are also active functional groups, which can undergo esterification reactions with acids under the action of catalysts to form ester compounds; they can also be oxidized to form other functional groups such as carbonyl groups.
In summary, N- (2,3-dihydroxypropyl) -4-bromobenzaldehyde contains a variety of functional groups, rich in chemical properties, and has important application value in the field of organic synthesis. Organic compounds with diverse structures can be constructed through various chemical reactions.
In this compound, the benzene ring endows it with certain stability and conjugated system characteristics. The bromine atom attached to the benzene ring, because the electronegativity of bromine is greater than that of carbon, causes the electron cloud to bias towards the bromine atom, which reduces the electron cloud density of the benzene ring, and the electrophilic substitution reaction activity is changed compared with the unsubstituted benzene ring. And the bromine atom can participate in nucleophilic substitution and other reactions, which is an important reaction check point. The existence of
aldehyde group (-CHO) makes the compound have typical aldehyde chemical properties. The aldehyde group has high reactivity and can undergo oxidation reactions. For example, under the action of appropriate oxidizing agents, it can be oxidized to carboxyl groups (-COOH); it can also occur reduction reactions, which can be reduced to alcohol hydroxyl groups (-CH 2O OH). At the same time, aldehyde groups can participate in nucleophilic addition reactions, such as addition reactions with compounds containing active hydrogen, such as alcohols and amines, to generate acetals, Schiff bases and other products.
2,3-Dihydroxypropyl is connected to the benzene ring, and two hydroxyl groups (-OH) can form intramolecular or intermolecular hydrogen bonds. Intramolecular hydrogen bonds can affect the physical properties of compounds, such as melting point and boiling point; intermolecular hydrogen bonds can enhance intermolecular forces, which also affect their solubility and other properties. Hydroxyl groups are also active functional groups, which can undergo esterification reactions with acids under the action of catalysts to form ester compounds; they can also be oxidized to form other functional groups such as carbonyl groups.
In summary, N- (2,3-dihydroxypropyl) -4-bromobenzaldehyde contains a variety of functional groups, rich in chemical properties, and has important application value in the field of organic synthesis. Organic compounds with diverse structures can be constructed through various chemical reactions.
What are the synthesis methods of N- (2,3-dichloropropyl) -4-bromobenzenesulfonamide
To prepare N- (2,3-dihydrobenzyl) -4-bromobenzamide, there are several synthesis methods as follows:
First, 4-bromobenzoic acid is used as the starting material. First, 4-bromobenzoic acid is co-heated with thionyl chloride to cause an acid chlorination reaction to obtain 4-bromobenzoyl chloride. In this step, thionyl chloride is used as a chlorination reagent, and heating can promote the reaction. The reaction between the two is violent, and careful temperature control and operation are required. Then, the prepared 4-bromobenzoyl chloride is reacted with 2,3-dihydrobenzylamine in a suitable solvent, such as dichloromethane, in the presence of acid binding agents such as triethylamine. Triethylamine can neutralize the hydrogen chloride generated by the reaction, promote the forward reaction, and finally obtain the target product N- (2,3-dihydrobenzyl) -4-bromobenzamide. This route is relatively simple, and the raw material 4-bromobenzoic acid is relatively common and easy to obtain. However, the reaction conditions of acylation need to be carefully controlled, and the reagents used are toxic and corrosive.
Second, 4-bromobenzoyl chloride and 2,3-dihydrobenzyl alcohol are used as starting materials. First, 4-bromobenzoyl chloride reacts with 2,3-dihydrobenzyl alcohol under the catalysis of a base to form the corresponding ester. Potassium carbonate and other alkali can be selected, and acetone can be selected as the solvent. After the reaction is completed, the resulting ester is carried out aminolysis. The ester is heated with excess ammonia or ammonia in a suitable solvent, such as ethanol, and ammonia can replace the alkoxy group in the ester group to obtain N- (2,3-dihydrobenzyl) -4-bromobenzamide. This route avoids the direct use of amines, and the operation is slightly easier. However, the steps are increased, and the aminolysis reaction conditions need to be optimized. During the aminolysis process, safety issues such as ammonia escape should be paid attention to.
Third, consider using 2,3-dihydrobenzyl amine and 4-bromobenzonitrile as raw materials. In the presence of suitable catalysts, such as transition metal catalysts, and suitable ligands, the two undergo an addition reaction, resulting in N- (2,3-dihydrobenzyl) -4-bromobenzamide. This method has high atomic economy, and the reaction is relatively green and environmentally friendly. However, transition metal catalysts are expensive and the reaction conditions are demanding, requiring precise control of temperature, pressure and catalyst dosage.
First, 4-bromobenzoic acid is used as the starting material. First, 4-bromobenzoic acid is co-heated with thionyl chloride to cause an acid chlorination reaction to obtain 4-bromobenzoyl chloride. In this step, thionyl chloride is used as a chlorination reagent, and heating can promote the reaction. The reaction between the two is violent, and careful temperature control and operation are required. Then, the prepared 4-bromobenzoyl chloride is reacted with 2,3-dihydrobenzylamine in a suitable solvent, such as dichloromethane, in the presence of acid binding agents such as triethylamine. Triethylamine can neutralize the hydrogen chloride generated by the reaction, promote the forward reaction, and finally obtain the target product N- (2,3-dihydrobenzyl) -4-bromobenzamide. This route is relatively simple, and the raw material 4-bromobenzoic acid is relatively common and easy to obtain. However, the reaction conditions of acylation need to be carefully controlled, and the reagents used are toxic and corrosive.
Second, 4-bromobenzoyl chloride and 2,3-dihydrobenzyl alcohol are used as starting materials. First, 4-bromobenzoyl chloride reacts with 2,3-dihydrobenzyl alcohol under the catalysis of a base to form the corresponding ester. Potassium carbonate and other alkali can be selected, and acetone can be selected as the solvent. After the reaction is completed, the resulting ester is carried out aminolysis. The ester is heated with excess ammonia or ammonia in a suitable solvent, such as ethanol, and ammonia can replace the alkoxy group in the ester group to obtain N- (2,3-dihydrobenzyl) -4-bromobenzamide. This route avoids the direct use of amines, and the operation is slightly easier. However, the steps are increased, and the aminolysis reaction conditions need to be optimized. During the aminolysis process, safety issues such as ammonia escape should be paid attention to.
Third, consider using 2,3-dihydrobenzyl amine and 4-bromobenzonitrile as raw materials. In the presence of suitable catalysts, such as transition metal catalysts, and suitable ligands, the two undergo an addition reaction, resulting in N- (2,3-dihydrobenzyl) -4-bromobenzamide. This method has high atomic economy, and the reaction is relatively green and environmentally friendly. However, transition metal catalysts are expensive and the reaction conditions are demanding, requiring precise control of temperature, pressure and catalyst dosage.
In which fields is N- (2,3-dichloropropyl) -4-bromobenzenesulfonamide used?
N- (2,3-dihydrobenzyl) -4-bromobenzothiazolinone is a useful organic compound that has shown important applications in many fields.
In the field of medicinal chemistry, this compound is often used as a key intermediate. Due to its unique chemical structure and the potential to combine with specific check points of biological macromolecules, it is widely used to develop new drugs. It can be seen in the creation of antibacterial drugs, anti-tumor drugs or drugs for the treatment of neurological diseases. By modifying and optimizing its structure, scientists can explore lead compounds with higher activity and selectivity, paving the way for the development of new drugs.
In the field of materials science, N- (2,3-dihydrobenzyl) -4-bromobenzothiazolinone can also play a unique role. Because it can participate in specific polymerization reactions to generate polymer materials with special properties. These materials may have excellent optical and electrical properties and can be used to manufacture optoelectronic devices such as organic Light Emitting Diodes (OLEDs) and solar cells. Or because they endow materials with good thermal stability and mechanical properties, they find application opportunities in the field of high-performance engineering plastics.
In the field of organic synthesis chemistry, it is a versatile synthesizer that participates in the construction of many complex organic molecules. The bromine atom and benzyl moiety in its structure can undergo a variety of chemical reactions, such as nucleophilic substitution reactions, coupling reactions, etc., which can introduce different functional groups to achieve diverse synthesis of organic molecules, providing organic synthesis chemists with a wealth of strategies and methods to help them create organic compounds with specific structures and functions.
In the field of medicinal chemistry, this compound is often used as a key intermediate. Due to its unique chemical structure and the potential to combine with specific check points of biological macromolecules, it is widely used to develop new drugs. It can be seen in the creation of antibacterial drugs, anti-tumor drugs or drugs for the treatment of neurological diseases. By modifying and optimizing its structure, scientists can explore lead compounds with higher activity and selectivity, paving the way for the development of new drugs.
In the field of materials science, N- (2,3-dihydrobenzyl) -4-bromobenzothiazolinone can also play a unique role. Because it can participate in specific polymerization reactions to generate polymer materials with special properties. These materials may have excellent optical and electrical properties and can be used to manufacture optoelectronic devices such as organic Light Emitting Diodes (OLEDs) and solar cells. Or because they endow materials with good thermal stability and mechanical properties, they find application opportunities in the field of high-performance engineering plastics.
In the field of organic synthesis chemistry, it is a versatile synthesizer that participates in the construction of many complex organic molecules. The bromine atom and benzyl moiety in its structure can undergo a variety of chemical reactions, such as nucleophilic substitution reactions, coupling reactions, etc., which can introduce different functional groups to achieve diverse synthesis of organic molecules, providing organic synthesis chemists with a wealth of strategies and methods to help them create organic compounds with specific structures and functions.
What is the market outlook for N- (2,3-dichloropropyl) -4-bromobenzenesulfonamide?
At present, in the market, the market situation and prospects of N- (2,3-dioxy-isopropyl) -4-bromobenzenamide can be discussed.
Looking at the pharmaceutical business in the world, these compounds are often involved in the creation of new drugs. In today's pharmaceutical industry, innovative drugs are of the utmost importance. If N- (2,3-dioxy-isopropyl) -4-bromobenzenamide has unique pharmacological activities, it may be important for those in pharmaceutical research and development. The research of new drugs is related to the health of all people, and the government also has many support policies. If there is a breakthrough in the use of this compound and it is included in the list of new drugs, the market prospects will be limitless.
Furthermore, the relationship between the chemical industry cannot be ignored. Such compounds may be an important corner of chemical synthesis, and in the field of fine chemicals, they can be used as raw materials for many downstream products. Today's fine chemicals are becoming more and more refined, specialized, and special, and the market demand is diverse. If N- (2,3-dioxy-isopropyl) -4-bromobenzamide has high efficiency and stability in the chemical synthesis process, it will be favored by chemical plants, and the market demand will also increase greatly.
However, the market situation changes, there are also hidden worries. First, the competition for similar competing products. The world is so big that there are many developers, or compounds with similar functions are competing in the market. If N- (2,3-dioxy-isopropyl) -4-bromobenzamide has no significant advantages, such as high cost or difficult synthesis, it may be difficult to take the lead in the market competition. Second, changes in regulations. Pharmaceutical and chemical industries are all tied to regulations. Stringent regulations, if N- (2,3-dioxy isopropyl) - 4-bromobenzenamide does not conform to the regulations of production and use, it will be restricted, and its market road will also be bumpy.
Overall, the market prospects of N- (2,3-dioxy isopropyl) - 4-bromobenzenamide, although there are good opportunities, there are also challenges. Businesspeople need to understand the changes in the market, study the characteristics of this product, reduce costs and increase efficiency, and act in compliance in order to gain a place in the market and make its prospects bright and broad.
Looking at the pharmaceutical business in the world, these compounds are often involved in the creation of new drugs. In today's pharmaceutical industry, innovative drugs are of the utmost importance. If N- (2,3-dioxy-isopropyl) -4-bromobenzenamide has unique pharmacological activities, it may be important for those in pharmaceutical research and development. The research of new drugs is related to the health of all people, and the government also has many support policies. If there is a breakthrough in the use of this compound and it is included in the list of new drugs, the market prospects will be limitless.
Furthermore, the relationship between the chemical industry cannot be ignored. Such compounds may be an important corner of chemical synthesis, and in the field of fine chemicals, they can be used as raw materials for many downstream products. Today's fine chemicals are becoming more and more refined, specialized, and special, and the market demand is diverse. If N- (2,3-dioxy-isopropyl) -4-bromobenzamide has high efficiency and stability in the chemical synthesis process, it will be favored by chemical plants, and the market demand will also increase greatly.
However, the market situation changes, there are also hidden worries. First, the competition for similar competing products. The world is so big that there are many developers, or compounds with similar functions are competing in the market. If N- (2,3-dioxy-isopropyl) -4-bromobenzamide has no significant advantages, such as high cost or difficult synthesis, it may be difficult to take the lead in the market competition. Second, changes in regulations. Pharmaceutical and chemical industries are all tied to regulations. Stringent regulations, if N- (2,3-dioxy isopropyl) - 4-bromobenzenamide does not conform to the regulations of production and use, it will be restricted, and its market road will also be bumpy.
Overall, the market prospects of N- (2,3-dioxy isopropyl) - 4-bromobenzenamide, although there are good opportunities, there are also challenges. Businesspeople need to understand the changes in the market, study the characteristics of this product, reduce costs and increase efficiency, and act in compliance in order to gain a place in the market and make its prospects bright and broad.
What are the safety and toxicity of N- (2,3-dichloropropyl) -4-bromobenzenesulfonamide?
N- (2,3 -dihydroxypropyl) -4 -bromophenoxybutyric acid, this substance is related to safety and toxicity and cannot be ignored.
In terms of its safety, under proper storage and use conditions, it can be relatively safe and secure. It needs to be stored in a cool, dry and well-ventilated place, away from fire, heat and strong oxidants to prevent unexpected chemical reactions. When using, operators should also follow strict procedures and wear appropriate protective equipment, such as protective gloves, goggles and masks, to avoid skin contact, eye contamination or inhalation of its dust and steam to ensure personal safety.
As for toxicity, it may affect organisms to varying degrees. After experimental investigation, it may be cytotoxic to some cell lines, interfering with the normal physiological function of cells, or causing cell growth inhibition and apoptosis. In animal experiments, if a certain dose is ingested, it may affect the function of organs, such as liver, kidney and other key organs for metabolism and detoxification, causing functional abnormalities. At the same time, it may be irritating to the skin and eyes, and can cause redness, swelling and pain after contact.
In addition, its environmental toxicity cannot be ignored. In the environment, if it is released without proper treatment, or migrated and transformed in water and soil, it will affect the ecological community such as aquatic organisms and soil microorganisms, and destroy the ecological balance. Therefore, the safety and toxicity of N- (2,3-dihydroxypropyl) -4-bromophenoxybutyric acid must be comprehensively and carefully considered, and all links from production, use to disposal should be strictly controlled to reduce its potential harm and protect human health and ecological environment.
In terms of its safety, under proper storage and use conditions, it can be relatively safe and secure. It needs to be stored in a cool, dry and well-ventilated place, away from fire, heat and strong oxidants to prevent unexpected chemical reactions. When using, operators should also follow strict procedures and wear appropriate protective equipment, such as protective gloves, goggles and masks, to avoid skin contact, eye contamination or inhalation of its dust and steam to ensure personal safety.
As for toxicity, it may affect organisms to varying degrees. After experimental investigation, it may be cytotoxic to some cell lines, interfering with the normal physiological function of cells, or causing cell growth inhibition and apoptosis. In animal experiments, if a certain dose is ingested, it may affect the function of organs, such as liver, kidney and other key organs for metabolism and detoxification, causing functional abnormalities. At the same time, it may be irritating to the skin and eyes, and can cause redness, swelling and pain after contact.
In addition, its environmental toxicity cannot be ignored. In the environment, if it is released without proper treatment, or migrated and transformed in water and soil, it will affect the ecological community such as aquatic organisms and soil microorganisms, and destroy the ecological balance. Therefore, the safety and toxicity of N- (2,3-dihydroxypropyl) -4-bromophenoxybutyric acid must be comprehensively and carefully considered, and all links from production, use to disposal should be strictly controlled to reduce its potential harm and protect human health and ecological environment.
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