Linshang Chemical
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N-(2,3-Dichloropropyl)-N-Phenyl-4-Chlorobenzenesulfonamide
Linshang Chemical
|
HS Code |
184593 |
| Chemical Formula | C15H13Cl3N2O2S |
| Molar Mass | 393.69 g/mol |
| Appearance | Solid (likely white or off - white powder) |
| Solubility | Insoluble in water, soluble in some organic solvents like dichloromethane, chloroform |
| Melting Point | Typically in a certain temperature range (specific value needs experimental determination) |
| Boiling Point | Requires experimental determination, but would be relatively high due to its molecular structure |
| Density | Needs experimental measurement |
| Vapor Pressure | Very low, as it is a solid at room temperature |
| Stability | Stable under normal storage conditions, but may react with strong oxidizing agents |
| Odor | May have a faint, characteristic chemical odor |
As an accredited N-(2,3-Dichloropropyl)-N-Phenyl-4-Chlorobenzenesulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500 - gram bags of N-(2,3 - dichloropropyl)-n - phenyl - 4 - chlorobenzenesulfonamide, well - sealed. |
| Storage | Store N-(2,3 - dichloropropyl)-n - phenyl - 4 - chlorobenzenesulfonamide in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly sealed container to prevent moisture absorption and contamination. Avoid storing near food or feedstuffs due to its chemical nature. |
| Shipping | Ship N-(2,3 - dichloropropyl)-n - phenyl - 4 - chlorobenzenesulfonamide in accordance with chemical shipping regulations. Ensure proper packaging to prevent leakage, and label clearly for safe and compliant transportation. |
Competitive N-(2,3-Dichloropropyl)-N-Phenyl-4-Chlorobenzenesulfonamide prices that fit your budget—flexible terms and customized quotes for every order.
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What is the chemical structure of N- (2,3-dichloropropyl) -N-phenyl-4-chlorobenzenesulfonamide?
The chemical structure of N- (2,3-dihydrobenzyl) -N-phenyl-4-hydroquinolinone is one of the structures of organic compounds. In its structure, there is a core skeleton of quinolinone. Quinolinone is a nitrogen-containing heterocycle with a conjugated system, which gives the compound specific chemical and physical properties.
In this structure, the hydrogen atom at the fourth position of 4-hydroquinolinone may affect its reactivity and intermolecular interactions. The N-phenyl part is connected to quinolinone by a nitrogen atom. Phenyl is an aromatic group with high electron cloud density and conjugate stability. The addition of molecular structure can change its electron distribution and spatial configuration, which has an impact on the solubility, spectral properties and biological activity of the compound.
Furthermore, N- (2,3-dihydrobenzyl), this substituent is also connected to quinolinone through nitrogen atoms. 2,3-dihydrobenzyl is a derivative of benzyl. Because of the single bond between the second and third parts of the benzene ring, but not the typical conjugated double bond of the benzene ring, the electron cloud distribution is different from that of ordinary benzyl. This structural modification may affect the stereochemistry of molecules, change the intermolecular forces, such as van der Waals forces, hydrogen bonds, etc., and then affect the stability, crystallinity and interaction with other molecules of the compound.
Overall, the chemical structure of N- (2,3-dihydrobenzyl) -N-phenyl-4-hydroquinolinone, through the combination and interaction of different groups, endows the compound with unique chemical and physical properties, which may have potential application value in organic synthesis, pharmaceutical chemistry and materials science.
In this structure, the hydrogen atom at the fourth position of 4-hydroquinolinone may affect its reactivity and intermolecular interactions. The N-phenyl part is connected to quinolinone by a nitrogen atom. Phenyl is an aromatic group with high electron cloud density and conjugate stability. The addition of molecular structure can change its electron distribution and spatial configuration, which has an impact on the solubility, spectral properties and biological activity of the compound.
Furthermore, N- (2,3-dihydrobenzyl), this substituent is also connected to quinolinone through nitrogen atoms. 2,3-dihydrobenzyl is a derivative of benzyl. Because of the single bond between the second and third parts of the benzene ring, but not the typical conjugated double bond of the benzene ring, the electron cloud distribution is different from that of ordinary benzyl. This structural modification may affect the stereochemistry of molecules, change the intermolecular forces, such as van der Waals forces, hydrogen bonds, etc., and then affect the stability, crystallinity and interaction with other molecules of the compound.
Overall, the chemical structure of N- (2,3-dihydrobenzyl) -N-phenyl-4-hydroquinolinone, through the combination and interaction of different groups, endows the compound with unique chemical and physical properties, which may have potential application value in organic synthesis, pharmaceutical chemistry and materials science.
What are the main uses of N- (2,3-dichloropropyl) -N-phenyl-4-chlorobenzenesulfonamide?
N- (2,3-dihydrobenzyl) -N-phenyl-4-hydrobenzylaniline, this compound has important uses in chemical and related fields.
In the field of medicinal chemistry, it can be used as an intermediate for drug synthesis. Because its structure contains specific aryl and benzyl groups, other functional groups can be introduced by chemical modification to construct molecular structures with specific pharmacological activities. For example, when developing certain neurological drugs, the characteristics of the compound structure can be used to attach specific active fragments through subsequent reactions, so that the obtained new compounds have the effect of regulating neurotransmitter transmission and improving neurological function, and then are used to treat neurological diseases such as Parkinson's disease and Alzheimer's disease.
In the field of materials science, this compound may be able to participate in the preparation of functional polymer materials. Its aromatic ring structure can endow the material with certain rigidity and stability, and the benzyl part may enhance the compatibility of the material with other substances. For example, in the preparation of optoelectronic functional polymer materials, this compound is used as one of the monomers and introduced into the polymer chain through polymerization reaction, which may improve the photoelectric properties of the material, such as improving the fluorescence emission efficiency and charge transfer ability of the material, etc., for the manufacture of organic Light Emitting Diode (OLED), solar cells and other optoelectronic devices.
In the field of organic synthetic chemistry, it is an important building block for organic synthesis. Due to its unique molecular structure, it can participate in a variety of organic reactions, such as nucleophilic substitution reactions, coupling reactions, etc. With the help of these reactions, more complex and diverse organic molecular structures can be further constructed, providing a foundation for the synthesis of organic compounds with special structures and properties, promoting the development of organic synthetic chemistry, and assisting the creation of new organic functional materials, drug lead compounds, etc.
In the field of medicinal chemistry, it can be used as an intermediate for drug synthesis. Because its structure contains specific aryl and benzyl groups, other functional groups can be introduced by chemical modification to construct molecular structures with specific pharmacological activities. For example, when developing certain neurological drugs, the characteristics of the compound structure can be used to attach specific active fragments through subsequent reactions, so that the obtained new compounds have the effect of regulating neurotransmitter transmission and improving neurological function, and then are used to treat neurological diseases such as Parkinson's disease and Alzheimer's disease.
In the field of materials science, this compound may be able to participate in the preparation of functional polymer materials. Its aromatic ring structure can endow the material with certain rigidity and stability, and the benzyl part may enhance the compatibility of the material with other substances. For example, in the preparation of optoelectronic functional polymer materials, this compound is used as one of the monomers and introduced into the polymer chain through polymerization reaction, which may improve the photoelectric properties of the material, such as improving the fluorescence emission efficiency and charge transfer ability of the material, etc., for the manufacture of organic Light Emitting Diode (OLED), solar cells and other optoelectronic devices.
In the field of organic synthetic chemistry, it is an important building block for organic synthesis. Due to its unique molecular structure, it can participate in a variety of organic reactions, such as nucleophilic substitution reactions, coupling reactions, etc. With the help of these reactions, more complex and diverse organic molecular structures can be further constructed, providing a foundation for the synthesis of organic compounds with special structures and properties, promoting the development of organic synthetic chemistry, and assisting the creation of new organic functional materials, drug lead compounds, etc.
What are the physicochemical properties of N- (2,3-dichloropropyl) -N-phenyl-4-chlorobenzenesulfonamide
N- (2,3-dihydrobenzyl) -N-phenyl-4-hydrobenzoxazinone, this compound has unique physical and chemical properties. Its appearance is often in a specific form, mostly crystalline or powdery, and the color varies according to the preparation conditions and purity. It is either white or slightly yellowish.
Regarding solubility, this substance exhibits certain solubility properties in organic solvents. Halogenated hydrocarbon solvents such as chloroform and dichloromethane have good solubility and can promote uniform dispersion of molecules. In addition, polar aprotic solvents such as dimethyl sulfoxide can also dissolve this substance well, due to the formation of specific interactions with molecules, such as hydrogen bonds or van der Waals forces, which enhance solubility.
Melting point is one of its important physical properties. After determination, the melting point of the substance is in a specific range, which is a key indicator for identification and purity judgment. The melting point of high-purity samples is relatively stable and accurate. If it contains impurities, the melting point may be offset or the melting range may be widened.
From the perspective of chemical properties, there are multiple activity check points in this compound. The structure of benzoxazinone gives it certain reactivity and can participate in various organic reactions. For example, under appropriate conditions, it can react with nucleophiles. Nucleophiles attack specific carbon atoms on the benzoxazinone ring, initiate ring opening or substitution reactions, and then construct new carbon-heteroatom bonds or carbon-carbon bonds, laying the foundation for the synthesis of more complex organic molecules. At the same time, N-phenyl and N- (2,3-dihydrobenzyl) parts also affect their reactivity, because their electronic effects can change the molecular charge distribution and affect the reaction check point activity, making the compound potentially valuable in the field of organic synthesis.
Regarding solubility, this substance exhibits certain solubility properties in organic solvents. Halogenated hydrocarbon solvents such as chloroform and dichloromethane have good solubility and can promote uniform dispersion of molecules. In addition, polar aprotic solvents such as dimethyl sulfoxide can also dissolve this substance well, due to the formation of specific interactions with molecules, such as hydrogen bonds or van der Waals forces, which enhance solubility.
Melting point is one of its important physical properties. After determination, the melting point of the substance is in a specific range, which is a key indicator for identification and purity judgment. The melting point of high-purity samples is relatively stable and accurate. If it contains impurities, the melting point may be offset or the melting range may be widened.
From the perspective of chemical properties, there are multiple activity check points in this compound. The structure of benzoxazinone gives it certain reactivity and can participate in various organic reactions. For example, under appropriate conditions, it can react with nucleophiles. Nucleophiles attack specific carbon atoms on the benzoxazinone ring, initiate ring opening or substitution reactions, and then construct new carbon-heteroatom bonds or carbon-carbon bonds, laying the foundation for the synthesis of more complex organic molecules. At the same time, N-phenyl and N- (2,3-dihydrobenzyl) parts also affect their reactivity, because their electronic effects can change the molecular charge distribution and affect the reaction check point activity, making the compound potentially valuable in the field of organic synthesis.
What is the synthesis method of N- (2,3-dichloropropyl) -N-phenyl-4-chlorobenzenesulfonamide?
To prepare N- (2,3-dihydrobenzyl) -N-phenyl-4-hydroquinoline formamide, the following method can be used.
First, 4-hydroquinoline is used as the starting material. In an appropriate reaction vessel, an appropriate amount of solvent, such as toluene, dichloromethane, etc., is added to dissolve it to form a homogeneous solution. Then add bases, such as potassium carbonate, sodium carbonate, etc. The function of bases is to promote the reaction and adjust the pH of the reaction system. Then add halogenated benzyl derivatives, such as 2,3-dihydrobenzyl halide, where halogen atoms (such as chlorine, bromine, etc.) can undergo nucleophilic substitution reactions with nitrogen atoms on 4-hydroquinoline. The temperature and reaction time need to be controlled during the reaction. Generally speaking, the temperature can be maintained between room temperature and 50 ° C. The reaction takes several hours to ten hours until the reaction reaches the desired level. The reaction process can be monitored by thin-layer chromatography (TLC). This step can obtain the intermediate product 4- (2,3-dihydrobenzyl) -4-hydroquinoline.
Take the intermediate product from the above, place it in another reaction vessel, and add a suitable solvent, such as N, N-dimethylformamide (DMF). Put in phenyl isocyanate, which is the key reagent for introducing N-phenyl group. During the reaction process, an appropriate amount of catalyst, such as organotin catalyst, may be added to speed up the reaction rate. Control the reaction temperature in a certain range, such as 50 ° C to 80 ° C, and the reaction lasts for several hours. After the reaction is completed, the target product N- (2,3-dihydrobenzyl) -N-phenyl-4-hydroquinoline formamide can be obtained after post-treatment operations, such as extraction, washing, drying, column chromatography separation, etc.
When operating, attention should be paid to the precise control of various reaction conditions, and the purity of the raw materials should also be strictly required, so as to improve the yield and purity of the product and successfully achieve the purpose of synthesis.
First, 4-hydroquinoline is used as the starting material. In an appropriate reaction vessel, an appropriate amount of solvent, such as toluene, dichloromethane, etc., is added to dissolve it to form a homogeneous solution. Then add bases, such as potassium carbonate, sodium carbonate, etc. The function of bases is to promote the reaction and adjust the pH of the reaction system. Then add halogenated benzyl derivatives, such as 2,3-dihydrobenzyl halide, where halogen atoms (such as chlorine, bromine, etc.) can undergo nucleophilic substitution reactions with nitrogen atoms on 4-hydroquinoline. The temperature and reaction time need to be controlled during the reaction. Generally speaking, the temperature can be maintained between room temperature and 50 ° C. The reaction takes several hours to ten hours until the reaction reaches the desired level. The reaction process can be monitored by thin-layer chromatography (TLC). This step can obtain the intermediate product 4- (2,3-dihydrobenzyl) -4-hydroquinoline.
Take the intermediate product from the above, place it in another reaction vessel, and add a suitable solvent, such as N, N-dimethylformamide (DMF). Put in phenyl isocyanate, which is the key reagent for introducing N-phenyl group. During the reaction process, an appropriate amount of catalyst, such as organotin catalyst, may be added to speed up the reaction rate. Control the reaction temperature in a certain range, such as 50 ° C to 80 ° C, and the reaction lasts for several hours. After the reaction is completed, the target product N- (2,3-dihydrobenzyl) -N-phenyl-4-hydroquinoline formamide can be obtained after post-treatment operations, such as extraction, washing, drying, column chromatography separation, etc.
When operating, attention should be paid to the precise control of various reaction conditions, and the purity of the raw materials should also be strictly required, so as to improve the yield and purity of the product and successfully achieve the purpose of synthesis.
What are the precautions for using N- (2,3-dichloropropyl) -N-phenyl-4-chlorobenzenesulfonamide?
N- (2,3-dihydrobenzyl) -N-phenyl-4-hydrobenzodiazine resin is a unique organic compound. During use, the following numbers must be paid attention to:
First, safety protection is essential. This compound may be toxic and irritating to a certain extent. When operating, you must wear protective clothing, protective gloves and goggles, and beware of skin contact and eye splashing. If you come into contact accidentally, you should immediately rinse with plenty of water and seek medical treatment as appropriate. And because it may evaporate specific harmful gases, the operation should be carried out in a well-ventilated place, or with the help of ventilation equipment, to ensure air quality and avoid harmful gases being inhaled into the body.
Second, storage conditions must be appropriate. It should be stored in a cool, dry and ventilated place, away from fire and heat sources. Due to its chemical properties or affected by temperature and humidity, improper storage or deterioration will affect its performance. And it should be stored separately from oxidizing agents, acids and other substances to prevent chemical reactions from occurring and causing danger.
Third, when using, it is crucial to precisely control the dosage and reaction conditions. In different reactions, the required dosage of this compound may vary, and it needs to be accurately weighed according to specific experiments or production requirements. At the same time, reaction temperature, time, solvent and other conditions also have a great impact on the reaction result. If the reaction temperature is too high or too long, or the product performance is poor, it is necessary to strictly follow the established process procedures to ensure the smooth progress of the reaction and obtain the ideal product.
Fourth, since it is an organic compound, it has potential impact on the environment or storage. After use, the waste should be properly disposed of in accordance with relevant regulations and cannot be discarded at will. It needs to be specially recycled or treated harmlessly to reduce the harm to the environment.
First, safety protection is essential. This compound may be toxic and irritating to a certain extent. When operating, you must wear protective clothing, protective gloves and goggles, and beware of skin contact and eye splashing. If you come into contact accidentally, you should immediately rinse with plenty of water and seek medical treatment as appropriate. And because it may evaporate specific harmful gases, the operation should be carried out in a well-ventilated place, or with the help of ventilation equipment, to ensure air quality and avoid harmful gases being inhaled into the body.
Second, storage conditions must be appropriate. It should be stored in a cool, dry and ventilated place, away from fire and heat sources. Due to its chemical properties or affected by temperature and humidity, improper storage or deterioration will affect its performance. And it should be stored separately from oxidizing agents, acids and other substances to prevent chemical reactions from occurring and causing danger.
Third, when using, it is crucial to precisely control the dosage and reaction conditions. In different reactions, the required dosage of this compound may vary, and it needs to be accurately weighed according to specific experiments or production requirements. At the same time, reaction temperature, time, solvent and other conditions also have a great impact on the reaction result. If the reaction temperature is too high or too long, or the product performance is poor, it is necessary to strictly follow the established process procedures to ensure the smooth progress of the reaction and obtain the ideal product.
Fourth, since it is an organic compound, it has potential impact on the environment or storage. After use, the waste should be properly disposed of in accordance with relevant regulations and cannot be discarded at will. It needs to be specially recycled or treated harmlessly to reduce the harm to the environment.
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