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N-(2,3-Dichloropropyl)-N-Phenylbenzenesulfonamide
Linshang Chemical
|
HS Code |
376387 |
| Chemical Formula | C15H13Cl2NO2S |
| Molar Mass | 344.24 g/mol |
| Appearance | Solid (usually) |
| Physical State At Room Temp | Solid |
| Odor | Typically has a characteristic odor |
| Solubility In Water | Low solubility |
| Solubility In Organic Solvents | Soluble in some organic solvents |
| Melting Point | Varies, needs specific experimental data |
| Boiling Point | Varies, needs specific experimental data |
| Density | Data - specific to experimental determination |
| Vapor Pressure | Low vapor pressure |
As an accredited N-(2,3-Dichloropropyl)-N-Phenylbenzenesulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500 - gram bags of N-(2,3 - dichloropropyl)-n - phenylbenzenesulfonamide chemical packaging. |
| Storage | Store N-(2,3 - dichloropropyl)-n - phenylbenzenesulfonamide in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly sealed container to prevent moisture absorption and potential reactions. Label the storage clearly to avoid misidentification. |
| Shipping | N-(2,3 - dichloropropyl)-n - phenylbenzenesulfonamide, a chemical, must be shipped in accordance with strict hazardous materials regulations. Use appropriate packaging to prevent leakage and ensure proper labeling for safe transport. |
Competitive N-(2,3-Dichloropropyl)-N-Phenylbenzenesulfonamide prices that fit your budget—flexible terms and customized quotes for every order.
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As a leading N-(2,3-Dichloropropyl)-N-Phenylbenzenesulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of N- (2,3-dichloropropyl) -N-phenylbenzenesulfonamide?
N- (2,3-dihydroxypropyl) -N-benzylbenzyloxycarbonyl tryptophan, which is a crucial intermediate in the field of organic synthesis and medicinal chemistry. Its main uses are reflected in the following aspects:
In the field of drug research and development. First, in the research of anti-tumor drugs, it can be used as a key structural fragment. Through modification and modification, it is hoped to obtain anti-tumor compounds with higher activity and selectivity. Due to its structural properties, it may be able to precisely bind to specific targets in tumor cells and interfere with key physiological processes such as tumor cell growth and proliferation, opening up new avenues for conquering tumor diseases. Second, in the development of neurological drugs, with its unique chemical structure, or can regulate neurotransmitter transmission, nerve cell activity, etc., it is expected to develop drugs for the treatment of neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease, and help improve patients' cognitive function and movement disorders.
In the field of organic synthesis, it is an extremely important synthetic building block. With its multiple activity check points, it can participate in a variety of organic reactions, such as nucleophilic substitution, esterification, amidation, etc. Chemists can use this as a starting material to ingeniously design reaction routes to construct complex and diverse organic compounds, expand the library of organic molecules, and provide a rich material basis for materials science, total synthesis of natural products, and other fields.
In the field of materials science, after rational design and modification, it can be introduced into polymer material systems. Giving materials special biocompatibility, optical properties or electrical properties, such as the preparation of biodegradable smart materials that can respond to specific biological signals, shows broad application prospects in biomedical engineering, sensors and other fields.
In the field of drug research and development. First, in the research of anti-tumor drugs, it can be used as a key structural fragment. Through modification and modification, it is hoped to obtain anti-tumor compounds with higher activity and selectivity. Due to its structural properties, it may be able to precisely bind to specific targets in tumor cells and interfere with key physiological processes such as tumor cell growth and proliferation, opening up new avenues for conquering tumor diseases. Second, in the development of neurological drugs, with its unique chemical structure, or can regulate neurotransmitter transmission, nerve cell activity, etc., it is expected to develop drugs for the treatment of neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease, and help improve patients' cognitive function and movement disorders.
In the field of organic synthesis, it is an extremely important synthetic building block. With its multiple activity check points, it can participate in a variety of organic reactions, such as nucleophilic substitution, esterification, amidation, etc. Chemists can use this as a starting material to ingeniously design reaction routes to construct complex and diverse organic compounds, expand the library of organic molecules, and provide a rich material basis for materials science, total synthesis of natural products, and other fields.
In the field of materials science, after rational design and modification, it can be introduced into polymer material systems. Giving materials special biocompatibility, optical properties or electrical properties, such as the preparation of biodegradable smart materials that can respond to specific biological signals, shows broad application prospects in biomedical engineering, sensors and other fields.
What are the physical properties of N- (2,3-dichloropropyl) -N-phenylbenzenesulfonamide
N- (2,3-dihydroxypropyl) -N-benzylbenzyloxycarbonyl tryptophan, this substance is an important member of the field of organic compounds. Its physical properties are quite unique, let me explain in detail.
Looking at its properties, under normal temperature and pressure, it is mostly in the form of a white to off-white solid, with a fine texture, like coagulation, pure appearance and no impurities, flashing under light with a faint and soft luster, just like a pearl hidden in the world.
When it comes to melting point, the melting point of this compound is within a specific range, and this value is one of its inherent properties, just like the unique identification of people. Accurate determination of melting point is of great significance for identifying its purity and identifying the characteristics of substances. The stability of the melting point reflects the relative stability and regularity of its molecular structure.
Solubility is also one of its important physical properties. In the selection of organic solvents, it shows a certain solubility preference. In some common organic solvents, such as dichloromethane, N, N-dimethylformamide, etc., it can be moderately dissolved, just like a fish getting water, and the molecules can stretch and disperse in the solvent. However, in water, its solubility is poor, which is closely related to the hydrophobic groups contained in the molecules. Hydrophobic groups make it difficult to form a good interaction with water molecules, so it is difficult to dissolve in water.
In addition, its density is also a key physical parameter. The size of the density reflects the mass distribution of the substance in a unit volume. Compared with other related substances, it has a specific numerical range. This value provides indispensable basic data for calculating the dosage and determining the reaction system in practical application scenarios such as chemical production and experimental operations.
In summary, the physical properties of N- (2,3-dihydroxypropyl) -N- benzylbenzyloxycarbonyl tryptophan, from appearance, melting point, solubility to density, are like pieces of a puzzle, together piecing together the unique physical properties of this compound, laying a solid foundation for further research on its chemical properties and practical applications.
Looking at its properties, under normal temperature and pressure, it is mostly in the form of a white to off-white solid, with a fine texture, like coagulation, pure appearance and no impurities, flashing under light with a faint and soft luster, just like a pearl hidden in the world.
When it comes to melting point, the melting point of this compound is within a specific range, and this value is one of its inherent properties, just like the unique identification of people. Accurate determination of melting point is of great significance for identifying its purity and identifying the characteristics of substances. The stability of the melting point reflects the relative stability and regularity of its molecular structure.
Solubility is also one of its important physical properties. In the selection of organic solvents, it shows a certain solubility preference. In some common organic solvents, such as dichloromethane, N, N-dimethylformamide, etc., it can be moderately dissolved, just like a fish getting water, and the molecules can stretch and disperse in the solvent. However, in water, its solubility is poor, which is closely related to the hydrophobic groups contained in the molecules. Hydrophobic groups make it difficult to form a good interaction with water molecules, so it is difficult to dissolve in water.
In addition, its density is also a key physical parameter. The size of the density reflects the mass distribution of the substance in a unit volume. Compared with other related substances, it has a specific numerical range. This value provides indispensable basic data for calculating the dosage and determining the reaction system in practical application scenarios such as chemical production and experimental operations.
In summary, the physical properties of N- (2,3-dihydroxypropyl) -N- benzylbenzyloxycarbonyl tryptophan, from appearance, melting point, solubility to density, are like pieces of a puzzle, together piecing together the unique physical properties of this compound, laying a solid foundation for further research on its chemical properties and practical applications.
What are the chemical properties of N- (2,3-dichloropropyl) -N-phenylbenzenesulfonamide?
N- (2,3 -dihydrobenzyl) -N-phenylbenzamide, an organic compound, is quite rich in chemical properties, which are described as follows:
From the structural point of view, the compound contains dihydrobenzyl and phenylbenzamide structural fragments. Dihydrobenzyl gives it a certain fat solubility, and the phenylbenzamide part is due to the benzene ring conjugation system, which has a profound impact on the overall properties.
In terms of physical properties, it is usually a solid. Due to the existence of van der Waals forces and benzene ring conjugation between molecules, the melting point is relatively high. Due to the presence of many hydrophobic groups, the solubility in water is poor, but it is easily soluble in common organic solvents, such as dichloromethane, chloroform, tetrahydrofuran, etc. This property is crucial for organic synthesis, separation and purification.
In terms of chemical properties, the amide bond in this compound has certain stability. However, under the condition of strong acid or strong base and heating, the amide bond can undergo hydrolysis reaction. In the case of strong acid, protonation is initiated first, and then water molecules attack, causing the amide bond to break, resulting in the formation of corresponding carboxylic acids and amines; in the case of strong base, the hydroxide ion attacks the carbonyl carbon, which also initiates the hydrolysis of the amide bond.
The benzene ring part can undergo a typical electrophilic substitution reaction. Because the benzene ring is rich in electrons, reactions such as halogenation, nitration, and sulfonation can occur. Taking halogenation as an example, under the catalysis of Lewis acid, it can react with halogen elements, and halogen atoms replace hydrogen atoms on the benzene ring.
In addition, the dihydrobenzyl moiety also has certain reactivity. Its methylene hydrogen atoms can be activated under appropriate conditions to participate in reactions such as alkylation and acylation, and then realize molecular structure modification and derivatization.
In the field of organic synthesis, N- (2,3 -dihydrobenzyl) -N-phenylbenzamide is often used as an intermediate. With its diverse reaction check points, more complex organic molecular structures can be constructed through a series of reactions. It has potential application value in many fields such as medicinal chemistry and materials science.
From the structural point of view, the compound contains dihydrobenzyl and phenylbenzamide structural fragments. Dihydrobenzyl gives it a certain fat solubility, and the phenylbenzamide part is due to the benzene ring conjugation system, which has a profound impact on the overall properties.
In terms of physical properties, it is usually a solid. Due to the existence of van der Waals forces and benzene ring conjugation between molecules, the melting point is relatively high. Due to the presence of many hydrophobic groups, the solubility in water is poor, but it is easily soluble in common organic solvents, such as dichloromethane, chloroform, tetrahydrofuran, etc. This property is crucial for organic synthesis, separation and purification.
In terms of chemical properties, the amide bond in this compound has certain stability. However, under the condition of strong acid or strong base and heating, the amide bond can undergo hydrolysis reaction. In the case of strong acid, protonation is initiated first, and then water molecules attack, causing the amide bond to break, resulting in the formation of corresponding carboxylic acids and amines; in the case of strong base, the hydroxide ion attacks the carbonyl carbon, which also initiates the hydrolysis of the amide bond.
The benzene ring part can undergo a typical electrophilic substitution reaction. Because the benzene ring is rich in electrons, reactions such as halogenation, nitration, and sulfonation can occur. Taking halogenation as an example, under the catalysis of Lewis acid, it can react with halogen elements, and halogen atoms replace hydrogen atoms on the benzene ring.
In addition, the dihydrobenzyl moiety also has certain reactivity. Its methylene hydrogen atoms can be activated under appropriate conditions to participate in reactions such as alkylation and acylation, and then realize molecular structure modification and derivatization.
In the field of organic synthesis, N- (2,3 -dihydrobenzyl) -N-phenylbenzamide is often used as an intermediate. With its diverse reaction check points, more complex organic molecular structures can be constructed through a series of reactions. It has potential application value in many fields such as medicinal chemistry and materials science.
What is the production method of N- (2,3-dichloropropyl) -N-phenylbenzenesulfonamide?
To prepare N- (2,3 -dihydrobenzyl) -N-phenylbenzamide, the following method can be used.
First take an appropriate amount of benzoic acid, put it in a reactor, and react with sulfite chloride. In this process, sulfite chloride is used as a chlorination reagent. When the two react, the temperature should be controlled in a moderate range, such as between 40 and 60 degrees Celsius, and sufficiently stirred to make the reaction proceed smoothly, benzoyl chloride can be obtained. The reaction formula is: benzoic acid + sulfite chloride → benzoyl chloride + sulfur dioxide + hydrogen chloride.
Then the obtained benzoyl chloride is mixed with N- (2,3-dihydrobenzyl) aniline, and a suitable organic solvent, such as dichloromethane, can be selected to help the two mix uniformly. And add an appropriate amount of acid binding agent, such as triethylamine, to absorb the hydrogen chloride generated by the reaction. This reaction also needs to control the temperature. It is appropriate to be around room temperature and continue to stir. After a certain period of time, N- (2,3-dihydrobenzyl) -N-phenylbenzamide crude product can be obtained. The reaction mechanism is that the amino group of benzoyl chloride and N- (2,3-dihydrobenzyl) aniline undergoes nucleophilic substitution reaction.
After the reaction is completed, the crude product is purified. It can be washed with water to remove soluble impurities, and then extracted with organic solvents to collect the organic phase. Then, the organic phase is dried with anhydrous sodium sulfate to remove residual water. Finally, the solvent and other impurities are removed by means of reduced pressure distillation or column chromatography to obtain pure N- (2,3-dihydrobenzyl) -N-phenylbenzamide.
The whole preparation process requires precise control of the conditions of each reaction step, such as temperature, reagent dosage, reaction time, etc., and the operation should be carefully controlled, so that the ideal product yield and purity can be obtained.
First take an appropriate amount of benzoic acid, put it in a reactor, and react with sulfite chloride. In this process, sulfite chloride is used as a chlorination reagent. When the two react, the temperature should be controlled in a moderate range, such as between 40 and 60 degrees Celsius, and sufficiently stirred to make the reaction proceed smoothly, benzoyl chloride can be obtained. The reaction formula is: benzoic acid + sulfite chloride → benzoyl chloride + sulfur dioxide + hydrogen chloride.
Then the obtained benzoyl chloride is mixed with N- (2,3-dihydrobenzyl) aniline, and a suitable organic solvent, such as dichloromethane, can be selected to help the two mix uniformly. And add an appropriate amount of acid binding agent, such as triethylamine, to absorb the hydrogen chloride generated by the reaction. This reaction also needs to control the temperature. It is appropriate to be around room temperature and continue to stir. After a certain period of time, N- (2,3-dihydrobenzyl) -N-phenylbenzamide crude product can be obtained. The reaction mechanism is that the amino group of benzoyl chloride and N- (2,3-dihydrobenzyl) aniline undergoes nucleophilic substitution reaction.
After the reaction is completed, the crude product is purified. It can be washed with water to remove soluble impurities, and then extracted with organic solvents to collect the organic phase. Then, the organic phase is dried with anhydrous sodium sulfate to remove residual water. Finally, the solvent and other impurities are removed by means of reduced pressure distillation or column chromatography to obtain pure N- (2,3-dihydrobenzyl) -N-phenylbenzamide.
The whole preparation process requires precise control of the conditions of each reaction step, such as temperature, reagent dosage, reaction time, etc., and the operation should be carefully controlled, so that the ideal product yield and purity can be obtained.
What are the precautions for using N- (2,3-dichloropropyl) -N-phenylbenzenesulfonamide?
N- (2,3-dihydroxypropyl) -N-benzylbenzyloxycarbonyl amide When using this product, there are many things to be careful about.
First of all, this product has a specific chemical activity, and during operation, the established experimental procedures must be strictly followed. Do not let the skin come into direct contact with it. If you accidentally touch it, rinse it with plenty of water immediately, and depending on the severity of the situation, you may need to seek medical treatment. Because it may be irritating or even corrosive to the skin.
Furthermore, in terms of the use environment, you should choose a well-ventilated place. Because in some cases, it may evaporate gases that affect human health, good ventilation can effectively reduce such risks.
In addition, the storage of this chemical substance is also extremely critical. It needs to be stored in a cool, dry place away from fire and oxidants. Due to the characteristics of its chemical structure, it may be heated, exposed to fire or in contact with oxidants, or may cause violent chemical reactions, or even explode.
During measurement and use, the utensils used must be clean and dry. Trace impurities or moisture may interfere with the chemical reaction process and lead to deviations in experimental results.
When using, it is advisable to have a professional on hand to guide. If the user does not fully understand its chemical properties and operating specifications, it is easy to cause danger due to improper operation.
In short, such chemicals must be treated with a scientific and rigorous attitude in order to ensure the safety of the use process and avoid accidents.
First of all, this product has a specific chemical activity, and during operation, the established experimental procedures must be strictly followed. Do not let the skin come into direct contact with it. If you accidentally touch it, rinse it with plenty of water immediately, and depending on the severity of the situation, you may need to seek medical treatment. Because it may be irritating or even corrosive to the skin.
Furthermore, in terms of the use environment, you should choose a well-ventilated place. Because in some cases, it may evaporate gases that affect human health, good ventilation can effectively reduce such risks.
In addition, the storage of this chemical substance is also extremely critical. It needs to be stored in a cool, dry place away from fire and oxidants. Due to the characteristics of its chemical structure, it may be heated, exposed to fire or in contact with oxidants, or may cause violent chemical reactions, or even explode.
During measurement and use, the utensils used must be clean and dry. Trace impurities or moisture may interfere with the chemical reaction process and lead to deviations in experimental results.
When using, it is advisable to have a professional on hand to guide. If the user does not fully understand its chemical properties and operating specifications, it is easy to cause danger due to improper operation.
In short, such chemicals must be treated with a scientific and rigorous attitude in order to ensure the safety of the use process and avoid accidents.
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