Linshang Chemical
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N-Chloro-4-Methylbenzenesulfonamide
Linshang Chemical
|
HS Code |
210782 |
| Chemical Formula | C7H8ClNO2S |
| Molar Mass | 205.66 g/mol |
| Appearance | Solid (usually white or off - white) |
| Physical State At Room Temp | Solid |
| Solubility In Water | Low solubility |
| Solubility In Organic Solvents | Soluble in some organic solvents like dichloromethane |
| Boiling Point | Decomposes before boiling |
| Melting Point | 90 - 94 °C |
| Odor | May have a characteristic, somewhat pungent odor |
As an accredited N-Chloro-4-Methylbenzenesulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100 - gram vial of N - chloro - 4 - methylbenzenesulfonamide, tightly sealed. |
| Storage | N - chloro - 4 - methylbenzenesulfonamide should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly - sealed container to prevent moisture absorption and decomposition. Avoid storing near incompatible substances. This helps maintain its chemical stability and reduces the risk of safety hazards. |
| Shipping | N - chloro - 4 - methylbenzenesulfonamide is shipped in well - sealed containers to prevent leakage. It follows strict chemical transportation regulations, ensuring proper handling to avoid any potential hazards during transit. |
Competitive N-Chloro-4-Methylbenzenesulfonamide prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading N-Chloro-4-Methylbenzenesulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemistry of N-chloro-4-methylbenzenesulfonamide?
N-chloro-4-methylbenzenesulfonamide has unique chemical properties and is related to the display of many chemical properties. This substance is often active in chemical reactions.
Looking at its structure, the chlorine atom is connected to the benzenesulfonamide group, giving it a specific reactivity. The chlorine atom has strong electronegativity, which makes the molecular electron cloud uneven, making this substance easy to participate in nucleophilic substitution reactions. Under suitable reaction conditions, the chlorine atom can be replaced by nucleophilic reagents to derive a variety of products.
Furthermore, the presence of benzene rings also affects its chemical properties. The benzene ring has a conjugated system, which makes the molecule have a certain stability, but also provides an activity check point for the reaction. The methyl group on the benzene ring can affect the electron cloud density of the benzene ring, but it also has a significant impact on the overall reactivity.
In redox reactions, N-chloro-4-methylbenzenesulfonamide can play a specific role. The valence state of chlorine allows it to participate in oxidation reactions or be reduced by accepting electrons under appropriate conditions. In the field of organic synthesis, it is often used as a chlorination reagent or to participate in reactions to construct complex molecular structures.
In addition, the solubility of this substance is also part of its chemical properties. According to the principle of similar miscibility, its solubility in organic solvents may vary depending on molecular polarity, and this property also affects its dispersion and reaction process in chemical reactions.
In conclusion, N-chloro-4-methylbenzenesulfonamide has rich and diverse chemical properties and plays an important role in many reactions in organic chemistry, providing many possibilities for chemical research and synthesis.
Looking at its structure, the chlorine atom is connected to the benzenesulfonamide group, giving it a specific reactivity. The chlorine atom has strong electronegativity, which makes the molecular electron cloud uneven, making this substance easy to participate in nucleophilic substitution reactions. Under suitable reaction conditions, the chlorine atom can be replaced by nucleophilic reagents to derive a variety of products.
Furthermore, the presence of benzene rings also affects its chemical properties. The benzene ring has a conjugated system, which makes the molecule have a certain stability, but also provides an activity check point for the reaction. The methyl group on the benzene ring can affect the electron cloud density of the benzene ring, but it also has a significant impact on the overall reactivity.
In redox reactions, N-chloro-4-methylbenzenesulfonamide can play a specific role. The valence state of chlorine allows it to participate in oxidation reactions or be reduced by accepting electrons under appropriate conditions. In the field of organic synthesis, it is often used as a chlorination reagent or to participate in reactions to construct complex molecular structures.
In addition, the solubility of this substance is also part of its chemical properties. According to the principle of similar miscibility, its solubility in organic solvents may vary depending on molecular polarity, and this property also affects its dispersion and reaction process in chemical reactions.
In conclusion, N-chloro-4-methylbenzenesulfonamide has rich and diverse chemical properties and plays an important role in many reactions in organic chemistry, providing many possibilities for chemical research and synthesis.
What are the main uses of N-chloro-4-methylbenzenesulfonamide?
N-chloro-4-methylbenzenesulfonamide, this substance has a wide range of uses. In the field of medicine, it is an important intermediate in organic synthesis. It can introduce chlorine atoms through specific reactions, change the molecular structure and activity, and help synthesize drugs with antibacterial, anti-inflammatory and other effects, improving the efficacy and pertinence of drugs.
In the field of pesticides, with its special chemical properties, it can participate in the synthesis of high-efficiency pesticides. By modifying benzene rings and sulfonamide groups, pesticides that have strong inhibitory and killing effects on specific pests or bacteria are created, escorting agricultural harvests.
In the field of materials science, it is also useful. In the synthesis of some functional polymer materials, N-chloro-4-methylbenzenesulfonamide can be used as a modifier to improve material properties, such as enhancing material stability, corrosion resistance, and expanding material application scenarios.
In addition, in organic chemistry research, as a commonly used reagent, it can be used to explore new reaction pathways and mechanisms. Researchers use it to participate in reactions, observe reaction phenomena, and analyze product structures, contributing to the development of organic chemistry theory. In short, N-chloro-4-methylbenzenesulfonamide plays a key role in many fields, promoting technological innovation and progress in various fields.
In the field of pesticides, with its special chemical properties, it can participate in the synthesis of high-efficiency pesticides. By modifying benzene rings and sulfonamide groups, pesticides that have strong inhibitory and killing effects on specific pests or bacteria are created, escorting agricultural harvests.
In the field of materials science, it is also useful. In the synthesis of some functional polymer materials, N-chloro-4-methylbenzenesulfonamide can be used as a modifier to improve material properties, such as enhancing material stability, corrosion resistance, and expanding material application scenarios.
In addition, in organic chemistry research, as a commonly used reagent, it can be used to explore new reaction pathways and mechanisms. Researchers use it to participate in reactions, observe reaction phenomena, and analyze product structures, contributing to the development of organic chemistry theory. In short, N-chloro-4-methylbenzenesulfonamide plays a key role in many fields, promoting technological innovation and progress in various fields.
What is the preparation method of N-chloro-4-methylbenzenesulfonamide?
The preparation of N-chloro-4-methylbenzenesulfonamide requires certain steps and materials. First, 4-methylbenzenesulfonamide is taken as the raw material, which is the basis for the initiation of the reaction. Place 4-methylbenzenesulfonamide in an appropriate reaction vessel, which must be clean and able to withstand the reaction conditions.
Then, introduce a chlorine-containing reagent. Commonly used such as chlorine gas, but the operation of chlorine gas should be cautious, because it is toxic and corrosive. Under specific reaction conditions, 4-methylbenzenesulfonamide reacts with chlorine gas. This reaction condition is quite critical. The temperature should be controlled within a certain range. If it is too high, side reactions will increase, and if it is too low, the reaction rate will be slow. Generally speaking, the temperature can be controlled between 0 ° C and 5 ° C, and this low temperature environment can be achieved by means of ice baths.
When reacting, stirring is also indispensable. Uniform stirring can make the reactants fully contact, speed up the reaction process, and promote a more complete reaction. Magnetic stirring or mechanical stirring can be used to ensure that the system is mixed evenly.
In addition to chlorine, other chlorine-containing reagents can also be used, such as sodium hypochlorite solution. If using sodium hypochlorite solution, pay attention to its concentration and the speed of dropwise addition. Slowly adding sodium hypochlorite solution dropwise can make the reaction proceed smoothly and avoid too violent reaction. At the same time, the pH of the reaction system needs to be adjusted to optimize the reaction environment. Usually it can be reacted under weakly alkaline conditions, such as using an appropriate amount of sodium bicarbonate and other regulators to maintain a suitable pH value.
When the reaction is over, it needs to go through the steps of separation and purification. It can be extracted with an organic solvent to enrich the product in the organic phase, and then further purified by distillation, recrystallization, etc., to obtain a pure N-chloro-4-methylbenzenesulfonamide product. In this way, the method of preparing this compound can be obtained.
Then, introduce a chlorine-containing reagent. Commonly used such as chlorine gas, but the operation of chlorine gas should be cautious, because it is toxic and corrosive. Under specific reaction conditions, 4-methylbenzenesulfonamide reacts with chlorine gas. This reaction condition is quite critical. The temperature should be controlled within a certain range. If it is too high, side reactions will increase, and if it is too low, the reaction rate will be slow. Generally speaking, the temperature can be controlled between 0 ° C and 5 ° C, and this low temperature environment can be achieved by means of ice baths.
When reacting, stirring is also indispensable. Uniform stirring can make the reactants fully contact, speed up the reaction process, and promote a more complete reaction. Magnetic stirring or mechanical stirring can be used to ensure that the system is mixed evenly.
In addition to chlorine, other chlorine-containing reagents can also be used, such as sodium hypochlorite solution. If using sodium hypochlorite solution, pay attention to its concentration and the speed of dropwise addition. Slowly adding sodium hypochlorite solution dropwise can make the reaction proceed smoothly and avoid too violent reaction. At the same time, the pH of the reaction system needs to be adjusted to optimize the reaction environment. Usually it can be reacted under weakly alkaline conditions, such as using an appropriate amount of sodium bicarbonate and other regulators to maintain a suitable pH value.
When the reaction is over, it needs to go through the steps of separation and purification. It can be extracted with an organic solvent to enrich the product in the organic phase, and then further purified by distillation, recrystallization, etc., to obtain a pure N-chloro-4-methylbenzenesulfonamide product. In this way, the method of preparing this compound can be obtained.
What are the precautions in storage and transportation of N-chloro-4-methylbenzenesulfonamide?
N-chloro-4-methylbenzenesulfonamide is a chemical substance. When storing and transporting, many things need to be paid attention to.
Let's talk about storage first. This substance is delicate and should be placed in a cool, dry and well-ventilated place. Because of the high temperature environment, it may cause its chemical properties to be unstable or decompose and so on. And keep away from fire and heat sources, both of which are dangerous. The place of storage must be separated from oxidizing agents, reducing agents, alkalis and other substances. If it encounters it, it is easy to cause chemical reactions or violent changes, endangering safety. In the warehouse, there should be suitable materials for containing leaks, just in case of leakage, which can be disposed of in time to prevent the situation from expanding.
Let's talk about transportation. Before transportation, make sure that the packaging is tight. Packaging materials must be able to resist vibration, collision and friction to prevent material leakage due to package damage. During transportation, always pay attention to changes in temperature and humidity, and strictly control the transportation environment. Transportation vehicles should also be clean, and no impurities that can react with them should be left. At the same time, transportation personnel must be professionally trained to be familiar with the characteristics of this substance and emergency treatment methods. If there is a leak during transportation, do not panic. According to the established emergency plan, take prompt measures, or evacuate the crowd, or properly collect the leak to avoid harm to the environment and people. In short, the storage and transportation of N-chloro-4-methylbenzenesulfonamide requires caution to ensure safety.
Let's talk about storage first. This substance is delicate and should be placed in a cool, dry and well-ventilated place. Because of the high temperature environment, it may cause its chemical properties to be unstable or decompose and so on. And keep away from fire and heat sources, both of which are dangerous. The place of storage must be separated from oxidizing agents, reducing agents, alkalis and other substances. If it encounters it, it is easy to cause chemical reactions or violent changes, endangering safety. In the warehouse, there should be suitable materials for containing leaks, just in case of leakage, which can be disposed of in time to prevent the situation from expanding.
Let's talk about transportation. Before transportation, make sure that the packaging is tight. Packaging materials must be able to resist vibration, collision and friction to prevent material leakage due to package damage. During transportation, always pay attention to changes in temperature and humidity, and strictly control the transportation environment. Transportation vehicles should also be clean, and no impurities that can react with them should be left. At the same time, transportation personnel must be professionally trained to be familiar with the characteristics of this substance and emergency treatment methods. If there is a leak during transportation, do not panic. According to the established emergency plan, take prompt measures, or evacuate the crowd, or properly collect the leak to avoid harm to the environment and people. In short, the storage and transportation of N-chloro-4-methylbenzenesulfonamide requires caution to ensure safety.
N-chloro-4-methylbenzenesulfonamide impact on the environment and human health
N-chloro-4-methylbenzenesulfonamide is also an organic compound. In this investigation, its impact on the environment and human health is described as follows:
For the environment, if this compound is released in nature, its fate is quite complicated. In water bodies, it may migrate with water currents, affecting aquatic ecology. Because it has certain chemical activity, or reacts with water substances. Aquatic organisms such as fish, plankton, etc., bear the brunt. It may interfere with its normal physiological functions, such as affecting the respiration and reproduction of fish. In the soil environment, or adsorbed by soil particles, it affects the activity and community structure of soil microorganisms. Then it affects the absorption of nutrients by plant roots and hinders plant growth and development. And its degradation rate in the environment may be slow, long-term residue or pollution accumulation.
As for human health, there are various ways of exposure to this compound. Inhalation through the respiratory tract can irritate the respiratory mucosa, causing cough, asthma and other uncomfortable symptoms. If exposed through skin, it may cause skin allergies, redness, swelling, and itching. Accidental ingestion can damage the digestive system, such as nausea, vomiting, and abdominal pain. In particular, this compound may be potentially carcinogenic. Long-term exposure may cause mutations in human body cells, increasing the risk of cancer. It may also interfere with the human endocrine system, affect hormone balance, and then have chain adverse effects on many physiological functions of the body.
In conclusion, N-chloro-4-methylbenzenesulfonamide poses a potential threat to both the environment and human health, and should be treated with caution and its use and discharge should be strictly controlled to ensure environmental safety and human well-being.
For the environment, if this compound is released in nature, its fate is quite complicated. In water bodies, it may migrate with water currents, affecting aquatic ecology. Because it has certain chemical activity, or reacts with water substances. Aquatic organisms such as fish, plankton, etc., bear the brunt. It may interfere with its normal physiological functions, such as affecting the respiration and reproduction of fish. In the soil environment, or adsorbed by soil particles, it affects the activity and community structure of soil microorganisms. Then it affects the absorption of nutrients by plant roots and hinders plant growth and development. And its degradation rate in the environment may be slow, long-term residue or pollution accumulation.
As for human health, there are various ways of exposure to this compound. Inhalation through the respiratory tract can irritate the respiratory mucosa, causing cough, asthma and other uncomfortable symptoms. If exposed through skin, it may cause skin allergies, redness, swelling, and itching. Accidental ingestion can damage the digestive system, such as nausea, vomiting, and abdominal pain. In particular, this compound may be potentially carcinogenic. Long-term exposure may cause mutations in human body cells, increasing the risk of cancer. It may also interfere with the human endocrine system, affect hormone balance, and then have chain adverse effects on many physiological functions of the body.
In conclusion, N-chloro-4-methylbenzenesulfonamide poses a potential threat to both the environment and human health, and should be treated with caution and its use and discharge should be strictly controlled to ensure environmental safety and human well-being.
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