N-Phenyl-N-((Trichloromethyl)Thio)Benzenesulfonamide
Linshang Chemical
HS Code |
571890 |
Chemical Formula | C13H10Cl3NO2S2 |
Molar Mass | 388.61 g/mol |
Appearance | Solid |
Color | Typically white to off - white |
Odor | May have a characteristic odor |
Solubility In Water | Low solubility |
Solubility In Organic Solvents | Soluble in some organic solvents like dichloromethane |
Melting Point | 113 - 115 °C |
Boiling Point | Decomposes before boiling |
Stability | Stable under normal conditions, but may react with strong oxidizing agents |
As an accredited N-Phenyl-N-((Trichloromethyl)Thio)Benzenesulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 500g of N - phenyl - n - ((trichloromethyl)thio)benzenesulfonamide in sealed plastic bags. |
Storage | N - phenyl - N - ((trichloromethyl)thio)benzenesulfonamide should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, ignition sources, and incompatible substances. Store in a tightly - sealed container to prevent moisture and air exposure, which could potentially lead to degradation or chemical reactions. Ensure storage areas comply with safety regulations. |
Shipping | N - phenyl - n - ((trichloromethyl)thio)benzenesulfonamide is a chemical. Shipping should comply with hazardous chemical regulations. It must be properly packaged to prevent leakage, and shipped with appropriate safety documentation. |
Competitive N-Phenyl-N-((Trichloromethyl)Thio)Benzenesulfonamide prices that fit your budget—flexible terms and customized quotes for every order.
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As a leading N-Phenyl-N-((Trichloromethyl)Thio)Benzenesulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
The first is a benzene ring, which is a six-membered carbon ring with a unique conjugated structure. It is a common structural unit of organic compounds, and the molecules are given with certain stability and hydrophobicity.
The second is a sulfonamide group, which is formed by connecting a sulfonyl group (-SO 2O -) with an amino group (-NH -). In the sulfonyl group, the sulfur atom is connected with two oxygen atoms by a double bond, which has strong electron absorption; in the amino group, the nitrogen atom has a lone pair of electrons, which can participate in the formation of hydrogen bonds or chemical reactions. This sulfonamide group gives the compound specific chemical activity and polarity.
In addition, (trichloromethyl) thiogroup, trichloromethyl (-CCl 🥰) is a strong electron-absorbing group, which affects the distribution of molecular electron clouds and chemical properties; the sulfur atom connects trichloromethyl to the benzene ring, which acts as a bridge, and its outer electronic structure makes the group have certain reactivity.
In summary, the chemical structure of N-phenyl-N- ((trichloromethyl) thio) benzenesulfonamide fuses multiple functional groups, and the interaction of each group determines the physicochemical properties and chemical reactivity of the compound.
It is also useful in industry. In some chemical production processes, it can be used as an intermediate. With its unique chemical properties, through a series of chemical reactions, it can be transformed into other more complex compounds with specific functions, providing various possibilities for industrial synthesis, and is of great significance in the field of new material research and development.
In the field of scientific research, N-phenyl-N - (trichloromethyl) thio) benzenesulfonamide has also attracted attention. By exploring its reaction characteristics and interactions with other substances, researchers deepen their understanding of the basic theory of organic chemistry, and open up new reaction paths for the subsequent creation of new compounds.
This compound is in the form of white to light yellow crystalline powder, which is quite delicate in appearance, like fine sand and dust. Its melting point is between 125 and 128 ° C. Within this temperature limit, it gradually melts from a solid state to a liquid state.
Its solubility also has characteristics. It can be better dissolved in common organic solvents such as acetone and dichloromethane, just like salt melting in water, which can form a uniform solution; however, its solubility in water is extremely poor, just like oil floating in water, it is difficult to melt with water.
This compound has certain stability, and can be stored for a long time at room temperature and pressure without easy chemical changes. However, under specific conditions such as high temperature and strong oxidants, it will also react, change its structure, and produce new substances.
Its smell is weak, close to a fine smell, with a light special smell, non-pungent and unpleasant smell, and it is also not a pleasant fragrance. Overall, the characteristics of its physical properties determine its application in specific fields such as pesticides and pharmaceutical intermediates.
First, benzenesulfonyl chloride, aniline and trichloromethyl sulfur chloride are used as raw materials. First, benzenesulfonyl chloride and aniline are reacted under suitable conditions, such as in the presence of bases (such as potassium carbonate, etc.) and in the environment of organic solvents (such as dichloromethane, toluene, etc.), and the two undergo nucleophilic substitution to generate N-phenylbenzenesulfonamide. Afterwards, N-phenylbenzenesulfonamide is reacted with trichloromethyl sulfur chloride again. This reaction may require heating or the help of specific catalysts (such as some transition metal salts) to promote the formation of N-phenyl-N- ((trichloromethyl) thio) benzenesulfonamide. This process requires attention to the control of reaction temperature, raw material ratio and reaction time. If the temperature is too high or the time is too long, or side reactions occur, which affects the purity and yield of the product.
Second, it can be started from phenylthiophenol. First, thiophenol is reacted with an appropriate protective group to protect the sulfur atom, and then through a series of reactions, such as reacting with a reagent containing trichloromethyl, trichloromethyl is introduced, and then the protective group is removed, and then reacts with benzenesulfonyl chloride to finally generate the target product. This route step is slightly complicated, but it can better control the reaction check point and improve the selectivity of the product. However, the separation and purification after each step of the reaction is quite critical, and suitable separation methods, such as column chromatography, recrystallization, etc., need to be used to remove impurities.
Third, using benzenesulfonamide as the starting material, through an appropriate activation step, the nitrogen atom is more nucleophilic, and then the nucleophilic substitution reaction occurs with the In this process, the choice of activator is particularly important. Improper activator may cause overreaction or increase side reactions. At the same time, the reaction solvent, reaction temperature and other conditions also need to be carefully adjusted to obtain the best reaction effect.
In short, there are various methods for synthesizing N-phenyl-N- ((trichloromethyl) thio) benzenesulfonamide, each with its own advantages and disadvantages. In actual operation, it is necessary to carefully select the appropriate synthesis route according to the existing conditions in the laboratory, the availability of raw materials, and the requirements for product purity and yield, and carefully optimize the reaction conditions to prepare this substance efficiently.
First, safety protection must be comprehensive. Because of its potential toxicity and irritation, protective clothing, protective gloves and goggles should be worn during contact. The operation should be carried out in a well-ventilated place or in a fume hood to prevent inhalation of its dust or vapor and damage to the respiratory system. If you accidentally come into contact with the skin or eyes, rinse with plenty of water immediately and seek medical attention in time.
Second, proper storage is also key. Keep in a cool, dry and ventilated place, away from fire and heat sources. Due to its chemical properties or instability, contact with certain substances or cause dangerous reactions, so it should be stored separately from oxidants, acids, alkalis, etc., and should not be mixed. At the same time, the storage area should be equipped with suitable materials to contain leaks.
Third, the use process is strictly operated according to specifications. Before use, read the relevant materials and safety instructions carefully to clarify its nature and latent risk. Accurately control the dosage and conditions of use, and do not change them at will. During experimental operation, follow the established steps and carefully observe the reaction phenomenon. If there is any abnormality, stop the operation immediately and take corresponding measures.
Fourth, waste disposal should not be ignored. After use, the remaining substances and waste should not be discarded at will. According to relevant regulations and environmental protection requirements, separate collection and treatment. Recycling can be considered. If it cannot be recycled, it needs to be professionally treated to ensure that the environment is not polluted.
In short, the use of N-phenyl-N- ((trichloromethyl) thio) benzenesulfonamide must put safety and standards first, and operate with caution, so as to avoid accidents and ensure personal safety and environmental safety.

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