N-Phenyl-N-(Trichloromethylsulfanyl)Benzenesulfonamide
Linshang Chemical
HS Code |
584017 |
Chemical Formula | C13H10Cl3NO2S2 |
Molecular Weight | 386.71 |
Appearance | Typically a solid |
Physical State At Room Temperature | Solid |
Odor | May have a characteristic odor |
Solubility In Water | Low solubility in water |
Solubility In Organic Solvents | Soluble in some organic solvents |
Melting Point | Varies, specific data needed from literature |
Boiling Point | Varies, specific data needed from literature |
Stability | Stable under normal conditions |
Hazard Class | May be classified as a hazardous substance, specific class depends on regulations |
As an accredited N-Phenyl-N-(Trichloromethylsulfanyl)Benzenesulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 500 - gram bottle of N - phenyl - n - (trichloromethylsulfanyl)benzenesulfonamide, well - sealed. |
Storage | N - phenyl - N - (trichloromethylsulfanyl)benzenesulfonamide should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent moisture and air exposure. Store it separately from incompatible substances like strong oxidizers and bases to avoid potential reactions. |
Shipping | N -phenyl - n - (trichloromethylsulfanyl)benzenesulfonamide is a chemical. Shipping should be in accordance with strict hazardous material regulations, using properly labeled containers and appropriate transport means to ensure safety during transit. |
Competitive N-Phenyl-N-(Trichloromethylsulfanyl)Benzenesulfonamide prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading N-Phenyl-N-(Trichloromethylsulfanyl)Benzenesulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
In industry, it plays a role in the manufacturing process of some special materials. For example, in the production of some plastic products that require strict chemical stability, the addition of this substance can enhance the material's resistance to chemical corrosion, improve its durability, and expand the application range of materials, so that it can be used in more complex and harsh environmental conditions.
In addition, in specific scientific research experiments, it acts as a special chemical reagent for researchers to explore certain chemical reaction mechanisms and synthesize new compounds. Scientists use its special chemical structure and properties to design and implement various experiments to promote the development and progress of chemical science and lay the foundation for the research and development of new chemical synthesis methods and materials.
In terms of melting point, it is about 110-120 ° C. The melting point range causes it to undergo phase transformation under specific temperature conditions. In the process of organic synthesis, separation and purification, the purity of the substance can be identified by melting point determination according to this melting point characteristic. If the melting point of the sample matches the standard value and the melting range is narrow, it indicates that the purity is high; if it deviates from the standard value or the melting range is wider, it indicates that there may be impurities.
In terms of solubility, it is insoluble in water, but soluble in some organic solvents, such as dichloromethane, chloroform, acetone, etc. The property of insolubility in water makes it effective in separating from water-soluble substances in systems involving water phases. The characteristic of being soluble in organic solvents is conducive to acting as a reactant or product in organic synthesis reactions. The reaction environment is constructed with the help of organic solvents to complete various organic reactions. At the same time, when the product is extracted and refined, it can also use its solubility difference to achieve separation and purification.
In addition, the compound is denser than water, and in experiments or industrial operations involving stratification, it will be in the lower layer. This property helps to separate the phase according to the density difference in the separation process, so as to achieve the separation and enrichment of substances.
In summary, the physical properties of N-phenyl-n- (trichloromethylsulfanyl) benzenesulfonamide are of great significance in the synthesis, analysis, separation and many other fields of organic chemistry, and are the key basis for in-depth research and application of this compound.
Its appearance is often white to light yellow crystalline powder, which is quite stable at room temperature and pressure. This substance is insoluble in water, but easily soluble in organic solvents such as dichloromethane, chloroform, acetone, etc. The phenyl ring and sulfonamide groups contained in the molecular structure give it a certain lipophilicity.
From the perspective of chemical activity, the trichloromethyl sulfur base in this compound is active. The strong electron-absorbing effect of chlorine atoms in trichloromethyl reduces the electron cloud density of sulfur atoms, making it easier for sulfur atoms to react with nucleophiles. For example, in the case of nucleophiles containing active hydrogen, such as alcohols and amines, the sulfur atoms in the trichloromethyl thio group can be substituted with them to form new sulfur-containing derivatives.
Furthermore, benzenesulfonamide groups also have certain chemical activities. Lone pair electrons on nitrogen atoms can participate in coordination reactions to form complexes with metal ions. At the same time, sulfonamide groups may undergo hydrolysis under acidic or basic conditions. In acidic media, hydrolysis produces benzenesulfonic acid and corresponding amines; in alkaline environments, hydrolysis produces benzenesulfonate and amines. Due to its unique chemical properties, N-phenyl-N- (trichloromethylthio) benzenesulfonamide is widely used in the field of organic synthesis. It is often used as an intermediate for the preparation of various complex organic compounds containing sulfur and nitrogen. It has important applications in many fields such as medicinal chemistry and materials science.
First, prepare benzenesulfonyl chloride, aniline and trichloromethyl thiochloride and other raw materials. In a clean reactor, dissolve the aniline with an appropriate amount of organic solvent, such as dichloromethane or chloroform, to create a homogeneous reaction environment. Slowly add benzenesulfonyl chloride dropwise. When adding dropwise, the reaction temperature should be strictly controlled to maintain a low range, usually 0 to 5 degrees Celsius. This step is a nucleophilic substitution reaction between the amino group of aniline and the acyl chloride group of benzenesulfonyl chloride to form N-phenylbenzenesulfonamide.
After the above reaction is completed, the temperature of the reaction system is raised to room temperature, and then trichloromethyl sulfur chloride is slowly added. This process also requires close attention to the change of temperature, because the reaction may be more violent. The sulfur atom in the trichloromethyl sulfur chloride reacts with the nitrogen atom of the N-phenylbenzenesulfonamide, and finally forms N-phenyl-N- (trichloromethylthio) benzenesulfonamide.
After the reaction is completed, the reaction mixture is post- First wash with an appropriate amount of dilute alkali solution to remove unreacted acid and other acidic impurities. Then wash with saturated saline water to reduce the water content in the organic phase. After that, the organic phase is dried with a desiccant such as anhydrous sodium sulfate or magnesium sulfate to remove the remaining water. Finally, the product is separated and purified by reduced pressure distillation or column chromatography, and the corresponding fractions or eluents are collected to obtain pure N-phenyl-N - (trichloromethylthio) benzenesulfonamide.
First, safety protection must be comprehensive. This substance may be toxic and irritating. When coming into contact, you need to wear suitable protective equipment, such as gloves, protective glasses and protective clothing, and beware of direct contact with the skin and eyes. If you come into contact inadvertently, you should immediately rinse with plenty of water and seek medical treatment according to the specific situation.
Second, the operating environment is also very critical. During use, it is necessary to ensure that the place is well ventilated to prevent the accumulation of harmful gases. It is best to carry out relevant operations in the fume hood, which can effectively reduce the harm of harmful gases to the human body and protect the health of the operator.
Third, storage should not be underestimated. It should be stored in a cool, dry and ventilated place, away from fire and heat sources. At the same time, it needs to be stored separately from oxidants, acids, alkalis and other substances to avoid reactions and hazards.
Fourth, when using, it should be strictly in accordance with the established operating procedures. Precisely control the dosage, and do not increase or decrease at will. Waste generated during use should not be discarded at will, and relevant regulations should be followed and properly disposed of to prevent pollution to the environment.
In conclusion, the use of N-phenyl-N- (trichloromethylthio) benzenesulfonamide requires constant caution and strict adherence to all precautions, so as to ensure the safety of the use process and avoid accidents.

Scan to WhatsApp