Ortho Nitrochlorobenzene
Linshang Chemical
HS Code |
642749 |
Name | Ortho Nitrochlorobenzene |
Chemical Formula | C6H4ClNO2 |
Molecular Weight | 157.55 g/mol |
Appearance | Yellowish - brown crystals |
Odor | Characteristic odor |
Melting Point | 32 - 33 °C |
Boiling Point | 245.5 °C |
Density | 1.368 g/cm³ (at 20 °C) |
Solubility In Water | Insoluble |
Solubility In Organic Solvents | Soluble in ethanol, ether, benzene |
Flash Point | 127 °C |
Vapor Pressure | 0.0133 kPa (20 °C) |
As an accredited Ortho Nitrochlorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 50 - kg drums for packaging Ortho - Nitrochlorobenzene, ensuring secure containment. |
Storage | Ortho - Nitrochlorobenzene should be stored in a cool, well - ventilated area away from heat, sparks, and open flames. Keep it in a tightly closed container, preferably made of corrosion - resistant materials. Separate it from oxidizing agents, reducing agents, and other incompatible substances to prevent potential reactions. Store in a location with proper spill - containment measures. |
Shipping | Ortho - Nitrochlorobenzene is shipped in tightly - sealed, corrosion - resistant containers. Due to its hazardous nature, it follows strict regulations, with proper labeling and handling to ensure safe transportation by road, rail, or sea. |
Competitive Ortho Nitrochlorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading Ortho Nitrochlorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
O-nitrochlorobenzene has a wide range of uses. In the dye industry, it is often a key intermediate for the preparation of a variety of azo dyes. By performing a series of chemical reactions with other compounds, it can synthesize colorful dyes to meet the needs of textile, printing and dyeing industries. In the field of medicine, it is also an important raw material for the synthesis of some drugs. After chemical transformation, it can prepare pharmaceutical ingredients with specific pharmacological activities. In the field of pesticides, it can be used as an intermediate for the synthesis of pesticides, fungicides and other pesticides, contributing to the control of agricultural pests and diseases.
The preparation method is mostly achieved by the nitrification and chlorination of benzene. First, benzene is reacted with mixed acid (a mixture of sulfuric acid and nitric acid) to form nitrobenzene. After the chlorination reaction, chlorine atoms are introduced into the adjacent position of the nitro group to obtain o-nitrochlorobenzene. However, this process requires strict control of the reaction conditions, such as temperature, reactant ratio, catalyst use, etc., to ensure the purity and yield of the product.
It should be noted that o-nitrochlorobenzene has certain toxicity and irritation, and is potentially harmful to human health. If it comes into contact with the skin inadvertently, it may cause irritation and allergic reactions; inhalation of its vapor, or cause respiratory discomfort, dizziness and other symptoms. In the environment, it is difficult to degrade, or cause pollution to soil, water, etc. Therefore, in the production, storage, and use of o-nitrochlorobenzene, strict safety regulations and environmental protection requirements must be followed to ensure that personnel safety and the environment are not damaged.
First, it is a key raw material in the dye industry. Due to its unique structure, the cover can be prepared through many chemical reactions to produce various dyes with bright colors and excellent performance. Taking the synthesis of azo dyes as an example, it can provide specific functional groups to enable the construction of dye molecules, which in turn endows the fabric with colorful colors, and has good light resistance, washable and other characteristics, which is indispensable in the textile printing and dyeing industry.
Second, it is also common in the field of pesticides. It can be used as an intermediate to synthesize a variety of high-efficiency pesticides. For example, some organochlorine pesticides, by virtue of their chemical properties, undergo a series of reactions and transformations to generate pesticide products with insecticidal, weeding and other effects, which can help agricultural production, ensure bumper crops, and resist the invasion of diseases and pests.
Third, it also has its function in the pharmaceutical industry. Can participate in the synthesis process of some drugs. Through precise chemical modification and reaction, pharmaceutical ingredients that have therapeutic effects on specific diseases are prepared, contributing to human health and well-being.
Fourth, in the field of organic synthesis, it is an important building block. Due to the nitro and chlorine atoms attached to the benzene ring, various other functional groups can be introduced through different chemical means, such as nucleophilic substitution, reduction, etc., to build complex organic molecular structures, providing basic raw materials for the development of organic synthetic chemistry.
In summary, orthogonal-nitrochlorobenzene plays an important role in the industrial fields of dyes, pesticides, medicine and organic synthesis, and plays a key role in promoting the development of various industries.
First take chlorobenzene as the raw material, which is the basis for preparation. Chlorobenzene has specific chemical properties and is suitable for subsequent reactions.
Then make chlorobenzene and mixed acids react together. For mixed acids, the mixture of nitric acid and sulfuric acid is also. Nitric acid is the key reagent for nitrification, while sulfuric acid has the effect of catalysis and dehydration. Under specific temperature, pressure and reaction time conditions, the hydrogen atom in the benzene ring of chlorobenzene is replaced by nitrophilic. In this reaction, the electron cloud density distribution of the benzene ring is consistent, and the ortho and para-sites are more active, so the nitro group easily replaces the hydrogen in this two position, and then the mixture of o-nitrochlorobenzene and p-nitrochlorobenzene If the temperature is too high, the side reactions will increase and the purity of the product will be disturbed; if the temperature is too low, the reaction rate will be slow, which will affect the yield. Usually, the reaction temperature is controlled in a moderate range, so that the reaction can proceed smoothly and efficiently.
After the reaction is completed, the product needs to be separated and purified. Due to the different physical properties of o-nitrochlorobenzene and p-nitrochlorobenzene, such as boiling point and solubility, etc., the two can be separated by distillation, crystallization, etc., to obtain pure o-nitrochlorobenzene and p-nitrochlorobenzene for industrial and scientific research purposes.
On its chemical properties, due to the connection of nitro and chlorine atoms on the benzene ring, its chemical activity is special. Nitro has strong electron absorption, which reduces the electron cloud density of the benzene ring, making the electrophilic substitution reaction more difficult. Although the chlorine atom is an ortho-para-position group, the strong electron absorption of the nitro group is dominant, so the new substituent is more into the meso.
O-nitrochlorobenzene can participate in many chemical reactions. One is the hydrolysis reaction, under specific conditions, the chlorine atom can be replaced by the hydroxyl group to obtain o-nitrophenol. The second is the reduction reaction, the nitro group can be gradually reduced, first forming the nitroso group, and then obtaining the amino group to form o-chloroaniline. Third, the nucleophilic substitution reaction can occur. Due to the electron absorption of the nitro group, the electron cloud density of the benzene ring is reduced, and the activity of the chlorine atom is increased, which is easily replaced by the attack of nucleophilic reagents.
O-nitrochlorobenzene is widely used in the field of organic synthesis. It is an important intermediate in the synthesis of medicines, dyes
The first heavy packaging is tight. It is lively. If the packaging is damaged, it will encounter air, moisture, etc., or cause quality changes, and there is a risk of leakage, endangering the surrounding environment and personal safety. Therefore, the packaging must be made of suitable materials and sealed to prevent leakage.
The second is the storage environment. It should be placed in a cool, dry and well-ventilated place. Avoid direct sunlight, because it is heated or caused by reactions, it will decompose and deteriorate. Humidity also needs to be controlled. High humidity or damp the product, which affects the quality. And it should be stored separately from oxidants, alkalis, etc. to prevent interaction and cause danger.
Furthermore, when transporting, relevant regulations must be followed. Use compliant transportation tools to ensure stability, and prevent vibration and collision damage to packaging during transportation. Transportation personnel must also be professionally trained and familiar with emergency response methods. In case of emergencies, they can respond quickly.
In addition, in the storage and transportation place, firefighting and emergency equipment should be prepared. Such as fire extinguishers, adsorption materials, etc., so that in the event of leakage or fire and other accidents, they can be dealt with in time to reduce damage.
In short, in the storage and transportation of orthogonal nitrochlorobenzene, every detail must be treated with caution, follow specifications, ensure process safety, and product quality.

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