P-Aminochlorobenzene

Linshang Chemical

Specifications

HS Code

904183

Chemical Formula C6H6ClN
Molar Mass 127.57 g/mol
Appearance Yellowish - brown solid
Odor Characteristic amine - like odor
Melting Point 70 - 72 °C
Boiling Point 232 - 234 °C
Solubility In Water Slightly soluble
Solubility In Organic Solvents Soluble in ethanol, ether, etc.
Density 1.21 g/cm³
Flash Point 110 °C
Pka 4.65

As an accredited P-Aminochlorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 25 - kg drum packaging for P - aminochlorobenzene chemical.
Storage p - aminochlorobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent moisture and air contact, which could lead to degradation. Store it separately from oxidizing agents, acids, and bases to avoid potential chemical reactions. Label the storage clearly for easy identification and safety.
Shipping P - aminochlorobenzene is shipped in tightly sealed, corrosion - resistant containers. It's transported under conditions that avoid heat, ignition sources, and incompatible substances to ensure safe delivery.
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P-Aminochlorobenzene P-Aminochlorobenzene
General Information
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Frequently Asked Questions

As a leading P-Aminochlorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the chemical structure of P-aminochlorobenzene?
P-aminochlorobenzene, the Chinese name is p-amino chlorobenzene. Its chemical structure is based on a benzene ring, which has the structure of a six-membered carbon ring, and the carbon and carbon are alternately connected by conjugated double bonds, forming a plane regular hexagonal shape. At the position of the benzene ring, one is a chlorine atom (-Cl) and the other is an amino group (-NH2O). The chlorine atom has an electron-absorbing induction effect, while the amino group has a donor-electron conjugation effect. The electronic effects of the two interact with each other on the benzene ring. This structure allows p-amino chlorobenzene to exhibit unique physical and chemical properties. Due to its benzene ring, it has certain stability; the existence of amino and chlorine atoms allows it to participate in a variety of chemical reactions, such as nucleophilic substitution, electrophilic substitution and other reactions, making it widely used in the field of organic synthesis.
What are the main uses of P-aminochlorobenzene?
P-Aminochlorobenzene, also known as p-chloroaniline, is an important raw material for organic synthesis, with a wide range of uses and key functions in many fields.
First, in the field of pharmaceutical synthesis, it can be used as an intermediate for the synthesis of a variety of drugs. For example, in the preparation of some antibacterial drugs, P-Aminochlorobenzene can be converted into substances with antibacterial activity through a series of chemical reactions, contributing to human resistance to bacterial invasion. For example, in the development of drugs for the treatment of cardiovascular diseases, it is also used as a starting material and has been ingeniously chemically modified to shape active ingredients that can regulate cardiovascular function.
Second, in the field of dye industry, P-Aminochlorobenzene is a key intermediate for the synthesis of various dyes. Due to its structural characteristics, it can react with other compounds to produce colorful and high-performance dyes. These dyes are widely used in textile, leather and other industries to impart brilliant colors to fabrics and leather, and enhance the aesthetics and commercial value of products.
Third, in the field of pesticides, it can be used to synthesize specific pesticides. By combining with other chemical substances, pesticide products with insecticides, weeding and other effects are generated, which can help agricultural production to control pests and diseases and ensure crop yield and quality.
Fourth, in the field of rubber additives, P-amino chlorobenzene participates in the synthesis of some rubber additives. These additives can improve the processing properties, physical properties and aging resistance of rubber, making rubber products such as tires and hoses more durable and widely used.
To sum up, P-aminochlorobenzene occupies an important position in many industrial fields such as medicine, dyes, pesticides, and rubber additives, and is of great significance for promoting the development of related industries.
What are the physical properties of P-aminochlorobenzene?
P-aminochlorobenzene is one of the organic compounds. It has unique physical properties and is detailed as follows:
- ** Appearance properties **: Under normal conditions, P-aminochlorobenzene is mostly white to light yellow crystals. If it is pure, the crystals are regular and the color is uniform. This form is easy to observe and process. In chemical operations, it is easy to weigh and transfer.
- ** Melting point **: The melting point is 72-73 ° C. When the temperature reaches this range, the solid P-aminochlorobenzene will gradually melt into a liquid state. The boiling point reaches 232 ° C. At this temperature, the liquid P-aminochlorobenzene will quickly transform into a gaseous state. This melting boiling point characteristic can be used by distillation, recrystallization and other methods in the process of separation and purification.
- ** Solubility **: Its solubility in water is poor, but it can be soluble in organic solvents such as ethanol, ether, and benzene. This difference in solubility is due to the molecular structure of P-aminochlorobenzene, which contains a hydrophobic benzene ring, so it is difficult to dissolve in polar water and has good compatibility with organic solvents. In organic synthesis reactions, suitable solvents can be selected accordingly to promote the reaction.
- ** Odor and density **: It has a weak special odor. Although this odor is not strong, it is also necessary to pay attention to ventilation when operating. Its density is slightly higher than that of water, about 1.298g/cm ³. In operations involving liquid-liquid separation or mixing, density characteristics can affect the stratification and distribution of substances.
- ** Stability **: Under normal conditions, P-aminochlorobenzene is quite stable. In case of open flames, hot topics, or contact with strong oxidants, there will be safety hazards, or may cause combustion, explosion and other accidents. Therefore, it must be avoided when storing and using.
What are P-aminochlorobenzene synthesis methods?
There are many ways to synthesize P-aminochlorobenzene. One method is to start with p-nitrochlorobenzene and obtain it by reduction. P-nitrochlorobenzene can be nitrified from chlorobenzene. Take chlorobenzene, mix acid (mixture of nitric acid and sulfuric acid), control its temperature and ratio, and get p-nitrochlorobenzene. Then, iron powder, hydrochloric acid as reducing agent, or catalytic hydrogenation method, so that the nitro group of p-nitrochlorobenzene is also an amino group, then get P-aminochlorobenzene.
There is also a method of using p-chloroaniline as diazonium salt, obtained by Sandmeier reaction. First take p-chloroaniline, react with sodium nitrite and hydrochloric acid, and prepare diazonium salt at low temperature. Then the diazonium salt is mixed with the hydrochloric acid solution of cuprous chloride. After heating, the diazonium group is replaced by a chlorine atom, and P-aminochlorobenzene is also obtained.
Others use benzene as the starting material. First chlorinate benzene to obtain chlorobenzene. Then aminize chlorobenzene, and then select a good catalyst and suitable reaction conditions in this step to have a considerable yield. Or after aminization and chlorination, P-aminochlorobenzene can also be obtained. It is only necessary to control the reaction check point so that the chlorine atom and the amino group form a pair structure. The methods of synthesis have advantages and disadvantages, depending on the ease of availability of raw materials, the level of cost, the amount of yield and the purity of the product. Use the best one.
P-aminochlorobenzene what are the precautions during use
P-Aminochlorobenzene is a commonly used material in chemistry. When using it, you must pay attention to all the important items.
The first thing to pay attention to is its toxicity. P-Aminochlorobenzene is toxic and can be harmful to the body if it is touched, inhaled or eaten. Users must wear suitable protective gear, such as gloves, masks, protective clothing, etc., to avoid direct contact with it, and operate it in a well-ventilated place to avoid its gas accumulation and harm to health.
The second time is the risk of its explosion. Although it is not extremely flammable, it is also at risk of explosion in case of open flames and hot topics. When storing, it must be kept away from fire and heat sources and placed in a cool, dry and well-ventilated place. It should also be stored separately from oxidizing agents to prevent them from causing danger.
Furthermore, when using this material for reaction, procedures must be followed. Precise temperature control, time control and material ratio. High or low temperature, long or short time, improper ratio, can cause reaction deviation, affect yield and quality, and even lead to danger.
In addition, the storage pipe of P-amino chlorobenzene should also be strict. Store it with a complete seal, and mark the product name, specification, date, etc. Check the storage condition regularly. If there is any leakage, take measures immediately.
In short, the use of P-aminochlorobenzene requires caution in terms of personal safety, reaction control, and storage to avoid risks and enable the chemical industry to move forward safely.
What is the chemistry of P-aminochlorobenzene?
P-amino chlorobenzene, also known as p-amino chlorobenzene, has unique chemical properties, so let me tell you in detail.
This substance has an amine group and a chlorine atom, both of which are key functional groups, giving it diversity. As far as the amine group is concerned, it is basic. Because the nitrogen atom has a lone pair of electrons, it can form a salt with the acid. If it encounters hydrochloric acid, it will generate a corresponding ammonium salt, just like the ancients bartered to achieve a new combination. And the amine group can participate in many nucleophilic substitution reactions, and can be used as a nucleophilic reagent. When it encounters electrophilic reagents such as halogenated hydrocarbons, the lone pair of nitrogen atoms attacks the electrophilic center. For example, a warrior holds a sword and takes the enemy's camp
The chlorine atom is above the benzene ring, and its properties are also active. Although the benzene ring is stable, the chlorine atom can participate in the nucleophilic substitution reaction. With the assistance of strong bases or high temperatures, the chlorine atom can be replaced by other nucleophilic reagents, as if the position is replaced by others. This is because the chlorine atom has a certain electronegativity, which makes the carbon-chlorine bond electron cloud biased towards chlorine, causing the carbon atom to be partially positively charged and vulnerable to attack by nucleophilic reagents.
Furthermore, the benzene ring of P-amino chlorobenzene, although stable, can participate in the electrophilic substitution reaction. Because the amine group is the power supply subgroup, the electron cloud density of the benzene Therefore, electrophilic reagents are prone to attack ortho and para-positions, and reactions such as halogenation, nitrification, and sulfonation occur, just like different guests follow the instructions to enter a specific location.
In addition, P-aminochlorobenzene also has some characteristic reactions. For example, when reacted with nitrous acid, the amine group will be converted into diazonium salts, which are extremely active and can undergo a variety of follow-up reactions to derive many organic compounds, just like opening a new door to the rich chemical world. In short, P-aminochlorobenzene is rich in chemical properties and has a wide range of uses in the field of organic synthesis. It can lay the foundation for many chemical reactions and achieve the birth of various organic compounds.
What are the main uses of P-aminochlorobenzene?
P-aminochlorobenzene, that is, p-chlorobenzene, is an important raw material for organic synthesis and has a wide range of uses.
First, in the field of medicine, it is often a key intermediate for the synthesis of many drugs. For example, synthetic antibacterial drugs, the part of the structure of p-chlorobenzene can be connected to other groups through specific chemical reactions, giving the drug antibacterial activity, helping it kill or inhibit bacterial growth, thereby treating infectious diseases. It is also used to synthesize pain-relieving drugs, which can relieve pain by regulating the signaling of the human nervous system.
Second, in the dye industry, p-chloroaniline plays an important role. Using it as a raw material can synthesize a variety of bright colors and excellent performance dyes. Such as azo dyes, p-chloroaniline is combined with other compounds through reactions such as diazotization to produce dyes with specific colors and stability. It is widely used in textiles, printing and dyeing and other industries to make fabrics rich in color.
Third, in terms of pesticides, it also has important uses. It can be used as an intermediate for synthetic pesticides, herbicides and other pesticides. Synthetic pesticides can precisely act on the specific physiological processes of pests, interfere with their normal growth and reproduction, achieve efficient insect control, and ensure crop yield and quality. Herbicides can selectively inhibit weed growth by p-chloroaniline, which is harmless to crops and maintains ecological balance in farmland.
Fourth, in the field of rubber additives, p-chloroaniline can synthesize some additives. For example, antioxidants can delay the aging of rubber products, enhance their anti-oxidation, anti-ozone and other properties, prolong the service life of rubber products, and are widely used in the production of rubber products such as tires and hoses.
Chloroaniline is indispensable in the pharmaceutical, dye, pesticide, rubber additives and other industries, and greatly promotes the development of related industries.
What is P-aminochlorobenzene production method?
P-aminochlorobenzene is an important category of organic compounds, and there are many methods for its preparation. In the past, p-nitrochlorobenzene was often used as the starting material for the preparation of P-aminochlorobenzene. P-nitrochlorobenzene has the counterposition of nitro and chlorine atoms in the benzene ring. To obtain P-aminochlorobenzene, the nitro group needs to be converted into an amino group.
One method is also a chemical reduction method. Iron powder and hydrochloric acid are often used as reducing agents. The p-nitrochlorobenzene is co-placed in a suitable reaction vessel with iron powder and hydrochloric acid, and heated to make it react. Among them, under the action of hydrochloric acid, iron powder forms ferrous ions. Ferrous ions are reductive, and the nitro group of p-nitrochlorobenzene can be gradually reduced to an amino group to obtain P-aminochlorobenzene. After the reaction is completed, the pure product is obtained through the steps of separation and purification. First, the unreacted iron powder is removed by filtration, and then the product is refined by distillation and extraction to improve its purity.
There is also a method of catalytic hydrogenation. Using p-nitrochlorobenzene as raw material, in the presence of a suitable catalyst, hydrogen is introduced. Commonly used catalysts, such as palladium carbon, platinum carbon, etc. Under suitable temperature and pressure conditions, hydrogen is adsorbed and activated on the surface of the catalyst, and reacts with the nitro group of p-nitrochlorobenzene. The nitro group is converted into an amino group by hydrogenation and reduction, and the final product is P-aminochlorobenzene. This catalytic hydrogenation method has advantages such as mild reaction conditions, high product purity, and low environmental pollution compared with the chemical reduction method. After the reaction, high purity P-aminochlorobenzene can be obtained by simple filtration, catalyst removal, distillation, crystallization, etc.
Both of these are common methods for preparing P-aminochlorobenzene. With the improvement of chemical technology, the preparation method has been continuously optimized and improved to meet the needs of industrial production and scientific research.
P-aminochlorobenzene to pay attention to when storing and transporting
"< Tiangong Kaiwu > Quasi-classical Chinese Questions and Answers"
For aminochlorobenzene, many matters must be observed during storage and transportation.
When storing, the first choice is the environment. When placed in a cool and dry place, away from fire and heat sources. Cover its nature or be disturbed by temperature and humidity, if it is in a high temperature and humid place, it may cause qualitative change and endanger safety. The ventilation of the warehouse must be good to make the air smooth to prevent the accumulation of harmful gases. And it needs to be stored separately from oxidants, acids and other substances. Because of its active chemical properties, mixing is prone to violent reactions, and the risk of explosion.
Furthermore, the choice of storage container is also the key. When using corrosion-resistant materials, such as special metal drums or plastic cans, seal tightly to prevent leakage. Always check the complete damage of the container, if there is leakage in the gap, dispose of it in time to avoid material loss and pollution.
When transporting, there are also precautions. Transportation vehicles must be equipped with corresponding fire equipment and leakage emergency treatment equipment for emergencies. During driving, drive slowly to avoid emergency brakes and bumps, so as to avoid the material from shaking violently in the container and causing accidents. Transportation personnel must be professionally trained and familiar with the characteristics of aminochlorobenzene and emergency treatment methods. When loading and unloading, handle it with care, and it is strictly forbidden to drop and press it to ensure the integrity of the material packaging.
All of these are important for the storage and transportation of p-aminochlorobenzene. Only with caution can we ensure its safety and avoid disasters.
P-aminochlorobenzene impact on the environment and human health
"Tiangong Kaiwu" is an ancient scientific and technological masterpiece in our country, with a simple and detailed style of writing. Today, in the style of ancient Chinese, it describes the impact of aminochlorobenzene on the environment and human health.
Aminochlorobenzene, in the environment, has a wide impact. If released in the atmosphere, or drifted with the wind, into cloud water, fall back to the earth. Its chemical properties are relatively stable, difficult to self-decompose, accumulated in water and soil, polluted soil and water sources. In water bodies, aquatic organisms bear the brunt. Or cause algae growth to be inhibited, affecting the primary production of water areas, breaking the foundation of the food chain. Contact with organisms such as fish and shrimp may damage their nervous and reproductive systems, reduce fertility, and after successive generations, the population may decrease.
As for the soil, or change the soil microbial community structure, hinder the decomposition of organic matter and nutrient circulation, reduce soil fertility, and affect crop growth. If crops are absorbed, they will remain in the fruit and enter the food chain, endangering human beings.
It is also very harmful to human health. Ingested into the human body through respiration, skin contact or diet. In the body, or react with cell components, damaging the normal function of cells. Long-term exposure can disturb the nervous system, causing headaches, dizziness, fatigue, insomnia, etc. What's more, it may cause blood system diseases, such as anemia, which hinders the synthesis of hemoglobin and reduces oxygen carrying capacity. And p-aminochlorobenzene has potential carcinogenicity, and exposure to its environment for a long time increases the risk of cancer. Pregnant women come into contact with or pass through the placenta, endangering fetal development and causing deformities.
In short, aminochlorobenzene is harmful to the environment and personal health. It should be handled with caution to prevent its escape and protect the environment and human well-being.