P-Bromochlorobenzene
Linshang Chemical
HS Code |
738336 |
Chemical Formula | C6H4BrCl |
Molar Mass | 191.45 g/mol |
Appearance | Colorless to pale yellow liquid |
Odor | Aromatic odor |
Density | 1.64 g/cm³ |
Boiling Point | 219 - 221 °C |
Melting Point | -6.2 °C |
Solubility In Water | Insoluble |
Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether |
Flash Point | 97 °C |
Vapor Pressure | Low vapor pressure at room temperature |
Stability | Stable under normal conditions |
As an accredited P-Bromochlorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 500g of p - bromochlorobenzene packaged in a sealed, corrosion - resistant bottle. |
Storage | P - bromochlorobenzene should be stored in a cool, dry, well - ventilated area, away from heat and ignition sources. It should be kept in a tightly - sealed container to prevent leakage. Store it separately from oxidizing agents and incompatible substances. Label the storage container clearly to ensure proper handling and safety. |
Shipping | P - bromochlorobenzene is shipped in tightly - sealed, corrosion - resistant containers. It's transported following strict chemical safety regulations, ensuring isolation from incompatible substances during transit to prevent hazards. |
Competitive P-Bromochlorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading P-Bromochlorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
The benzene ring has a unique conjugation system. The electron cloud is uniformly distributed between the rings, resulting in its properties different from ordinary olefins. Bromine and chlorine, both halogen elements, have strong electronegativity. It is connected to the benzene ring, and the electron cloud density distribution of the benzene ring is affected by the induction effect and the conjugation effect.
The antiposition of bromine and chlorine to the benzene ring results in higher molecular symmetry. The influence of the electronegativity of the two makes the electron cloud of the benzene ring biased towards the halogen atom, which decreases the activity of the electrophilic substitution reaction on the benzene ring slightly, and the substitution position is also controlled by the localization effect of the two. The atomic radii of bromine and chlorine are different, and they also affect the molecule in terms of spatial steric resistance, which in turn affects its physical and chemical properties. In this way, the chemical structure of P-bromochlorobenzene is approximated.
- ** Appearance properties **: This compound is colorless to light yellow needle-like or flake-like crystalline under normal conditions, and its shape is regular and its texture is uniform. Under light conditions or due to photochemical reactions, the color may become slightly darker, but it is still relatively stable.
- ** Melting point and boiling point **: The melting point is quite fixed, between about 63-65 ° C. Within this temperature limit, the substance gradually melts from solid to liquid. This melting point characteristic can be used as an important basis for judgment in the identification and purification process of the substance. The boiling point is about 219-221 ° C. At this temperature, the liquid p-bromochlorobenzene is converted into a gaseous state, achieving a phase transition. The boiling point reflects the strength of the intermolecular force, and the boiling point of p-bromochlorobenzene shows that the intermolecular force is moderate.
- ** Solubility **: p-bromochlorobenzene is insoluble in water, because water is a polar molecule, and the polarity of p-bromochlorobenzene is relatively weak. According to the principle of "similar miscibility", the two are difficult to dissolve each other. However, it is soluble in organic solvents such as ethanol, ether, and benzene. This organic solvent is mostly weakly polar or non-polar, and is similar to the intermolecular force of p-bromochlorobenzene, so it can miscible with each other. This solubility is widely used in organic synthesis and
- ** Density **: The density is slightly higher than that of water, about 1.841g/cm ³. When p-bromochlorobenzene coexists with water, it will sink at the bottom of the water due to its high density. This density difference can be used to achieve preliminary separation of substances in experiments and industrial production processes involving liquid-liquid separation.
- ** Odor and Volatility **: p-bromochlorobenzene has a special aromatic smell. Although the smell is not strong and pungent, it still has a certain volatility. Under normal temperature, some p-bromochlorobenzene molecules will escape from the solid or liquid surface into the air. This volatility requires necessary protective measures to be taken during use and storage to prevent excessive inhalation and harm to health.
In drug synthesis, p-bromochlorobenzene can undergo a series of reactions to construct a specific structure of drug active molecules, providing an important starting material for the development of new drugs. In the field of pesticide manufacturing, it can be used as a basic raw material for the synthesis of pesticides with high insecticidal, bactericidal or herbicidal properties, contributing to the pest control and crop protection of agricultural production.
In the dye industry, p-bromochlorobenzene is used as the starting material and synthesized through multi-step reaction. It has the characteristics of bright color and good fastness. It is widely used in textile, printing and dyeing industries to give rich colors to fabrics.
In addition, p-bromochlorobenzene has also been involved in the field of materials science, which can be used to prepare functional materials and pave the way for the development and application of new materials. It occupies an important position in organic synthesis and related industrial production and plays an indispensable role.
First, take chlorobenzene as the starting material and make it react with the brominating agent. Bromine can be selected to react in the presence of a catalyst. Commonly used catalysts, such as iron filings or iron tribromide. This reaction mechanism involves the electrophilic substitution of bromine positive ions to the benzene ring of chlorobenzene. The chlorine atom of chlorobenzene is an ortho-para-site group. Because of its electron-giving conjugation effect and electron-absorbing induction effect, and the conjugation effect is dominant, the electron cloud density of the ortho-para-site of the benzene ring is relatively increased, and bromine positive ions are easy to attack the ortho- Although two kinds of products can be obtained theoretically, due to the steric hindrance, the proportion of para-products is relatively high. After separation and purification, P-bromochlorobenzene can be obtained.
Second, bromobenzene is used as the raw material and interacts with the chlorinating agent. The chlorinating agent can be selected from chlorine gas, which reacts in the presence of a suitable catalyst. The catalyst can be such as ferric chloride. In this process, chlorine gas generates chlorine positive ions under the action of the catalyst, which initiates electrophilic substitution of the benzene ring of bromobenzene. The positioning effect of bromine atoms is similar to that of chlorine atoms, and they are both ortho-para-sites. However, the volume of bromine atoms is larger, and the influence of spatial steric hindrance is even greater, so that the proportion of
Third, bromobenzene can be obtained by bromination of benzene first, and then chlorinated; or chlorinated to obtain chlorobenzene first, and then brominated. However, these two pathways need to be carefully regulated to increase the yield of P-bromochlorobenzene and inhibit the formation of polyhalogenated by-products. In actual operation, the reaction temperature, the proportion of reactants, the amount of catalyst and other factors have a great influence on the reaction results, and it is necessary to repeatedly explore and optimize in order to obtain the ideal preparation effect.
The choice of the first environment. This substance should be stored in a cool and ventilated storehouse. It should be protected from heat, under high temperature, or cause chemical changes, which is dangerous. And the warehouse must be kept away from fire and heat sources to prevent the disaster of combustion. The temperature of the storehouse should be controlled within a specific range, and it should not be too high, which will cause its stability to be lost.
The importance of packaging. The packaging must be tight to prevent it from leaking. The packaging material should be corrosion-resistant, because P-bromochlorobenzene may react with certain materials. On the outside of the package, when there is a clear label, stating the name of the product, characteristics, hazards and emergency response methods, so that the handler can see at a glance.
Furthermore, when handling, be careful. Porters should wear appropriate protective equipment, such as protective clothing, gloves, goggles, etc., to avoid direct contact with the substance. During loading and unloading, load lightly and unload lightly. Do not make the container collide or tip over to prevent damage and leakage.
Also, the storage place should be separated from oxidants, acids, alkalis, etc., and must not be mixed. Due to its chemical properties, or violent reactions with various substances, causing disasters. And the warehouse should have suitable materials to deal with possible leakage.
During transportation, strict regulations must also be followed. The selected transportation vehicles should meet the requirements for the transportation of hazardous chemicals. When transporting, follow the specified route to avoid crowded areas and important facilities. Transportation personnel must be professionally trained and familiar with emergency treatment methods, so as to ensure the safety of P-bromochlorobenzene storage and transportation.
The density of P-bromochlorobenzene is 1.841g/cm ³, which is heavier than water. If placed in water, it will sink to the bottom. And it is difficult to dissolve in water, because water is a polar molecule, while P-bromochlorobenzene molecules have weak polarity. According to the principle of similar compatibility, it is difficult to dissolve in water. However, it is soluble in many organic solvents, such as ethanol, ether, benzene, etc., because the force between organic solvents and P-bromochlorobenzene molecules is similar, and it can be miscible with each other.
In addition, P-bromochlorobenzene is volatile to a certain extent, and it will evaporate slowly in the air. Its smell is weak, but if it exists in large quantities, it can also be sensed by the sense of smell. This substance is more sensitive to light, and long-term exposure to light may cause chemical reactions, resulting in changes in its structure and properties. In short, the physical properties of P-bromochlorobenzene, its storage, use, etc., have an important impact.
1. ** Starting from benzene **:
- First, benzene is used as a raw material and brominated with bromine under the catalysis of FeBr. In this reaction, the hydrogen atom on the benzene ring is replaced by the bromine atom to form bromobenzene. The reaction principle is that the bromine is polarized under the action of the catalyst, and the positively charged part attacks the benzene ring to form an intermediate, and then the protons are removed to form bromobenzene. The reaction equation is:\ (C_ {6} H_ {6} + Br_ {2}\ xrightarrow [] {FeBr_ {3}} C_ {6} H_ {5} Br + HBr\).
- The obtained bromobenzene undergoes chlorination reaction with chlorine under the catalysis of FeCl. Since bromine is an ortho-para-site group, the electron cloud density of the benzene ring increases, and the chlorine atom is more likely to replace the hydrogen atom of the bromobenzene para-site, resulting in p-bromochlorobenzene. The reaction equation is:\ (C_ {6} H_ {5} Br + Cl_ {2}\ xrightarrow [] {FeCl_ {3}} C_ {6} H_ {4} BrCl + HCl\).
2. ** Starting from p-bromoaniline **:
- The diazotization reaction of p-bromoaniline with hydrochloric acid and sodium nitrite occurs at low temperature (0-5 ℃), and the amino group is converted to diazonium salt. This reaction requires strict temperature control, because the diazonium salt is unstable at higher temperatures. The reaction equation is:\ (C_ {6} H_ {4} BrNH_ {2} + NaNO_ {2} + 2HCl\ xrightarrow [] {0 - 5 ℃} C_ {6} H_ {4} BrN_ {2} Cl + NaCl + 2H_ {2} O\).
- The diazonium salt reacts with the hydrochloric acid solution of cuprous chloride, and the diazonium group is replaced by the chlorine atom to form p-bromochlorobenzene. This reaction is a kind of Sandmeyer reaction, and the cuprous chloride plays the role of transferring the chlorine atom. The reaction equation is:\ (C_ {6} H_ {4} BrN_ {2} Cl + CuCl\ xrightarrow [] {HCl} C_ {6} H_ {4} BrCl + N_ {2} ↑ + CuCl\).
The second is to use chlorobenzene as the starting material and brominate to produce P-bromochlorobenzene. Chlorobenzene can be obtained by substituting benzene and chlorine under the action of catalyst. After that, the chlorobenzene and bromine are reacted under suitable conditions, and the bromine atom replaces the hydrogen of the chlorine atom to obtain P-bromochlorobenzene. This path also requires precise control of the reaction conditions to prevent side reactions, such as the generation of ortho-substitution products.
No matter what method, fine material selection is required, the conditions are carefully adjusted, and the separation and purification after the reaction is also the key to obtain high-purity P-bromochlorobenzene.
When storing, the first environment. It should be placed in a cool and ventilated warehouse. This is because if the compound is exposed to high temperature, no ventilation, or causes chemical reactions, it endangers safety. The temperature of the warehouse should not be too high to prevent its volatilization, decomposition, damage to quality, and there is a risk of fire and explosion.
Furthermore, keep away from fires and heat sources. P-bromochlorobenzene encounters open flames, hot topics, or can burn, or even cause explosions. Therefore, in the warehouse, fireworks are strictly prohibited, and electrical equipment should also have explosion-proof functions.
The storage place should also be separated from oxidants, edible chemicals, etc., and should not be mixed. Because P-bromochlorobenzene comes into contact with oxidants, or reacts violently; it is mixed with edible chemicals, in case of leakage, or contamination and food supplies, endangering people's health.
As for transportation, there is also attention to it. Before transportation, make sure that the packaging is complete and sealed. If the packaging is damaged, P-bromochlorobenzene leaks, which not only pollutes the environment, but also poses a threat to the safety of transportation personnel. During transportation, make sure that the container does not leak, collapse, fall, or damage.
Transportation vehicles should be equipped with corresponding varieties and quantities of fire equipment and leakage emergency treatment equipment. Once there is an accident such as leakage on the way, it can be dealt with in time. And when transporting, it should follow the specified route and do not stop in densely populated areas and residential areas. In this way, the safety of P-bromochlorobenzene storage and transportation can be guaranteed.

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