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P-Carboxybenzenesulfonyl Chloridebenzoic Acid, 4-(Chlorosulfonyl)-

Linshang Chemical

Specifications

HS Code

842119

Chemical Formula C7H5ClO4S
Molecular Weight 220.63
Appearance Typically a solid
Physical State At Room Temp Solid
Odor Likely pungent due to sulfonyl chloride group
Solubility In Water Low solubility, hydrolyzes
Solubility In Organic Solvents Soluble in some organic solvents like dichloromethane
Reactivity Reactive towards nucleophiles, can form esters, amides etc. due to sulfonyl chloride group

As an accredited P-Carboxybenzenesulfonyl Chloridebenzoic Acid, 4-(Chlorosulfonyl)- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 4-(chlorosulfonyl)-P -carboxybenzenesulfonyl Chloridebenzoic Acid in sealed chemical - grade packaging.
Storage **Storage for 4-(Chlorosulfonyl) - p - carboxybenzenesulfonyl Chloridebenzoic Acid** Store this chemical in a cool, dry, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly - sealed container to prevent contact with moisture, as it may react with water. Separate it from incompatible substances like bases, reducing agents, and reactive metals to avoid potential hazardous reactions.
Shipping "P - carboxybenzenesulfonyl Chloridebenzoic Acid, 4-(chlorosulfonyl)-" is a chemical. Shipping should follow strict regulations. It must be properly packaged in corrosion - resistant containers, labeled clearly, and transported by carriers approved for handling such hazardous chemicals.
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P-Carboxybenzenesulfonyl Chloridebenzoic Acid, 4-(Chlorosulfonyl)- P-Carboxybenzenesulfonyl Chloridebenzoic Acid, 4-(Chlorosulfonyl)-
General Information
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Frequently Asked Questions

As a leading P-Carboxybenzenesulfonyl Chloridebenzoic Acid, 4-(Chlorosulfonyl)- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the use of P-carboxybenzenesulfonyl Chloridebenzoic Acid, 4- (chlorosulfonyl) -
4- (chlorosulfonyl) benzoic acid, also known as p-carboxylbenzenesulfonyl chloride, is widely used.
First, in the field of organic synthesis, it is a crucial intermediate. It can be used to prepare various organic compounds with special structures and functions. For example, it can react with amino-containing compounds to form amide bonds to build complex organic molecular structures, such as the preparation of some biologically active drug molecules and monomers of functional polymer materials. This is because both chlorosulfonyl groups and carboxyl groups have high reactivity, which is easy to chemically react with a variety of functional groups, providing rich possibilities for organic synthesis.
Second, in the field of medicinal chemistry, it can be used as a raw material to synthesize a variety of drugs. For example, some drugs with antibacterial and anti-inflammatory effects are constructed with the help of its special structure. Its carboxyl group and chlorosulfonyl group can participate in the key structure formation process of drug molecules. By rationally designing the reaction path, the activity and selectivity of drug molecules can be precisely regulated to meet the needs of different disease treatments.
Third, in the field of materials science, it can be used to prepare polymer materials with special properties. In the polymerization reaction, its chlorosulfonyl group can be polymerized with other monomers, giving the polymer material unique properties, such as improving the solubility, thermal stability and mechanical properties of the material. For example, in the preparation of some high-performance engineering plastics and special fibers, 4- (chlorosulfonyl) benzoic acid can be used as an important monomer or modifier to improve the comprehensive properties of materials and meet the stringent requirements of high-end materials.
P-carboxybenzenesulfonyl the physicochemical properties of Chloridebenzoic Acid, 4- (chlorosulfonyl) -
4- (chlorosulfonyl) benzoic acid, that is, P-carboxylbenzenesulfonyl chloride, this substance has many physical and chemical properties. Its appearance is often white to light yellow crystalline powder, like fine frost and snow, and may shimmer in sunlight.
The melting point of this substance is in a specific range, between about 100 and 105 degrees Celsius, just like a limit. When the temperature rises to this point, it will gradually melt from a solid state to a liquid state, just like ice and snow melting in the warm sun. In terms of boiling point, because it is easy to decompose during heating, there is no exact stable boiling point, just like the fleeting dream, it is difficult to figure out where its exact boiling point is.
In terms of solubility, it is insoluble in water, like an isolated island in water, and it is difficult to blend with water. However, in the world of organic solvents, it has different performance. It can be soluble in halogenated hydrocarbon solvents such as dichloromethane and chloroform, and can also find a place in aromatic hydrocarbon solvents such as toluene and xylene, just like a wanderer finding a habitat in a foreign land, in which it can be more evenly dispersed.
Chemically, 4 - (chlorosulfonyl) benzoic acid is very active. The chlorosulfonyl group in its molecule is like a dynamic dancer, which is prone to hydrolysis reaction. If it encounters water vapor, it quickly embraces water to generate 4-carboxybenzene sulfonic acid and hydrogen chloride, which is like a wonderful chemical trick. At the same time, it can also dance with alcohols, undergo alcoholysis reactions, and generate corresponding sulfonates and hydrogen chloride. On the stage of this reaction, it constantly changes its own form. And carboxyl groups are not to be outdone. They can interact with alkali substances to neutralize and form carboxylic salts and water, just like yin and yang, reaching a new balance. These lively chemical properties make it a magical key in the field of organic synthesis, which can open the door to the synthesis of many organic compounds, participate in the colorful chemical reaction process, and add many wonderful colors and possibilities to the world of organic synthesis.
P-carboxybenzenesulfonyl What is the preparation method of Chloridebenzoic Acid, 4- (chlorosulfonyl) -
The method for preparing 4- (chlorosulfonyl) benzoic acid (4 - (chlorosulfonyl) benzoic acid, that is, p-carboxybenzenesulfonyl chloride, P - carboxybenzenesulfonyl Chloride) is as follows:
First, use p-xylene as the starting material. In an appropriate reactor, add an appropriate amount of p-xylene and add a specific catalyst, such as some transition metal salts. Add an appropriate amount of chlorine to control the reaction temperature and pressure. This step aims to achieve the chlorination reaction of one methyl group in p-xylene to generate 4-chloromethyltoluene. This reaction requires attention to the rate of chlorine gas introduction, and the temperature should not be too high to prevent excessive chlorination.
Secondly, 4-chloromethyltoluene is oxidized. Select a suitable oxidizing agent, such as potassium permanganate or potassium dichromate, and adjust the reaction conditions in a suitable solvent. This oxidation process can oxidize another methyl of 4-chloromethyltoluene to a carboxyl group to obtain 4-chloromethylbenzoic acid. In this step, the amount of oxidant and reaction time need to be precisely controlled to avoid damage to the product structure caused by excessive oxidation.
Furthermore, chlorosulfonation of 4-chloromethylbenzoic acid is carried out. Place 4-chloromethylbenzoic acid in a specific reaction vessel and add chlorosulfonic acid as a chlorosulfonation reagent. In an appropriate temperature range, the sulfonyl chloride group of chlorosulfonic acid will replace the chlorine atom of chloromethyl in 4-chloromethylbenzoic acid to generate 4- (chlorosulfonyl) benzoic acid. This reaction process requires attention to the regulation of the reaction temperature. Due to the strong corrosiveness and reactivity of chlorosulfonic acid, improper temperature can easily lead to side reactions.
Preparation of 4- (chlorosulfonyl) benzoic acid requires multiple steps, and each step requires fine control of the reaction conditions to obtain a product with higher yield and purity.
P-carboxybenzenesulfonyl Chloridebenzoic Acid, 4- (chlorosulfonyl) - in which areas
4- (chlorosulfonyl) benzoic acid, also known as p-carboxylbenzenesulfonyl chloride, has applications in many fields.
In the field of pharmaceutical synthesis, it is often used as a key intermediate. Due to the active functional groups of this compound, it can participate in a variety of chemical reactions and help build complex drug molecular structures. For example, when developing specific targeted anti-cancer drugs, p-carboxylbenzenesulfonyl chloride can precisely introduce key structural fragments by reacting with organic molecules containing specific activity check points, thus endowing the drug with the ability to precisely act on cancer cell targets, improve drug efficacy and reduce damage to normal cells.
It also plays an important role in the field of materials science. When preparing high-performance polymer materials, p-carboxylbenzenesulfonyl chloride can participate in the polymerization reaction as a functional monomer. Its carboxyl group and sulfonyl chloride can react with other monomers such as condensation and polymerization, so that the obtained polymer has unique properties, such as excellent thermal stability, chemical stability and good solubility, etc., thereby expanding the application of polymers in high-end fields such as aerospace, electronics and electrical appliances.
In the field of fine chemical product manufacturing, p-carboxylbenzenesulfonyl chloride can be used to synthesize various high-quality dyes, pigments and surfactants. In dye synthesis, it can be used to react with specific aromatic amines to generate new dyes with bright color and excellent fastness, which can meet the needs of high-quality dyes in textile printing and dyeing industries. In the preparation of surfactants, after specific reactions, the prepared surfactants have excellent properties in reducing surface tension, emulsifying, and dispersing, and are widely used in industrial production such as daily chemicals and coatings.
P-carboxybenzenesulfonyl market outlook for Chloridebenzoic Acid, 4- (chlorosulfonyl) -
4- (chlorosulfonyl) benzoic acid, that is, p-carboxylbenzenesulfonyl chloride, has broad prospects and great potential in today's chemical market.
It is a crucial intermediate in the field of organic synthesis. With its unique chemical structure, it can participate in multiple chemical reactions, such as combining with alcohols, and can prepare a series of ester compounds with special properties, which are widely used in the manufacture of fine chemical products, such as fragrances and pharmaceutical intermediates. In the production of fragrances, the prepared ester products can endow fragrances with unique aroma and stability, and improve product quality, so the market demand continues to rise.
In the field of medicine, 4- (chlorosulfonyl) benzoic acid can be used to synthesize a variety of drug molecules. With the vigorous development of the modern pharmaceutical industry, investment in the research and development of new drugs continues to increase, and the demand for this compound is also rising. Many drugs with specific pharmacological activities need to use this as a key raw material in their synthesis path to build the core structure of drug molecules, thereby optimizing the efficacy and safety of drugs.
Furthermore, in terms of materials science, polymer materials synthesized from this raw material have excellent properties. For example, it can enhance the heat resistance, corrosion resistance and mechanical strength of materials. With the rise of high-tech industries, such as electronic information, aerospace and other fields, the demand for high-performance materials has surged, indirectly driving the growth of the market demand for 4- (chlorosulfonyl) benzoic acid.
However, although the market prospect is good, it also faces challenges. The production process needs to be carefully controlled, because its chemical properties are lively and the reaction conditions are strict, and the slightest carelessness will affect the product quality. And environmental pressure also exists, and the production process needs to properly dispose of waste to meet environmental regulations. Overall, 4- (chlorosulfonyl) benzoic acid has both opportunities and challenges in the chemical market, and the prospect is promising.