Linshang Chemical
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P-Chlorobenzene Sulfonamide
Linshang Chemical
|
HS Code |
394670 |
| Chemical Formula | C6H6ClNO2S |
| Molar Mass | 191.64 g/mol |
| Appearance | White to off - white crystalline powder |
| Odor | Odorless |
| Melting Point | 149 - 151 °C |
| Solubility In Water | Slightly soluble |
| Solubility In Organic Solvents | Soluble in some organic solvents like ethanol, acetone |
| Density | 1.48 g/cm³ |
| Ph | Neutral in aqueous solution |
| Stability | Stable under normal conditions |
As an accredited P-Chlorobenzene Sulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | P - chlorobenzene Sulfonamide in 1 - kg bags for secure and convenient packaging. |
| Storage | P - chlorobenzene Sulfonamide should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in tightly closed containers to prevent moisture absorption and contamination. Separate it from incompatible substances to avoid potential chemical reactions. This storage approach helps maintain its chemical integrity and ensures safety. |
| Shipping | P - chlorobenzene Sulfonamide is shipped in well - sealed containers, compliant with chemical transportation regulations. Packaging ensures protection from moisture and physical damage during transit to maintain product integrity. |
Competitive P-Chlorobenzene Sulfonamide prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy P-Chlorobenzene Sulfonamide in China?
As a trusted P-Chlorobenzene Sulfonamide manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading P-Chlorobenzene Sulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of P-chlorobenzene Sulfonamide?
The main uses of chlorobenzene and sulfonamide are related to many fields. In the field of medicine, their uses are very wide. Take sulfonamides as an example, p-chlorobenzene can be combined with sulfonamides through a specific reaction to make drugs with antibacterial effect. Sulfonamides can hinder the growth and reproduction of bacteria, and are often used to treat a variety of bacterial infections, such as respiratory tract infections, urinary tract infections, etc. They have played a key role in the history of medical treatment, saving the lives of many patients.
In agriculture, the related products of the two also have important uses. Some pesticides containing this ingredient can effectively control crop diseases and insect pests. By precisely acting on pests, inhibiting their growth or directly killing them, thereby ensuring the healthy growth of crops, improving the yield and quality of crops, and is of great significance to the stable development of agriculture.
In the field of materials science, some special materials involved in the synthesis of p-chlorobenzene and sulfonamide have unique properties. For example, some polymer materials, due to their related structures, exhibit good stability, corrosion resistance and other characteristics, and are widely used in industrial production, building materials and many other aspects, providing assistance for the innovation and development of materials.
Furthermore, in the fine chemical industry, these two are used as important raw materials or intermediates to participate in the synthesis of many fine chemicals. These fine chemicals are widely used in daily chemical, fragrance and other industries to enrich people's daily necessities and improve the quality of life. In short, p-chlorobenzene and sulfonamide play an indispensable role in many fields and have a profound impact on the development of human society.
In agriculture, the related products of the two also have important uses. Some pesticides containing this ingredient can effectively control crop diseases and insect pests. By precisely acting on pests, inhibiting their growth or directly killing them, thereby ensuring the healthy growth of crops, improving the yield and quality of crops, and is of great significance to the stable development of agriculture.
In the field of materials science, some special materials involved in the synthesis of p-chlorobenzene and sulfonamide have unique properties. For example, some polymer materials, due to their related structures, exhibit good stability, corrosion resistance and other characteristics, and are widely used in industrial production, building materials and many other aspects, providing assistance for the innovation and development of materials.
Furthermore, in the fine chemical industry, these two are used as important raw materials or intermediates to participate in the synthesis of many fine chemicals. These fine chemicals are widely used in daily chemical, fragrance and other industries to enrich people's daily necessities and improve the quality of life. In short, p-chlorobenzene and sulfonamide play an indispensable role in many fields and have a profound impact on the development of human society.
What are the chemical properties of P-chlorobenzene Sulfonamide
In the case of p-chlorobenzene, it has the structure of an aromatic ring, and the chlorine atoms on the ring can be changed due to reactions such as nucleophilic substitution. When exposed to bases, chlorine atoms can be replaced by nucleophilic groups such as hydroxyl groups to produce corresponding phenols. It can also react with reagents such as metals under light or heating to remove chlorine atoms or initiate other reactions.
As for sulfonamides, they contain sulfonyl groups and amino groups. Sulfonyl groups have electron-absorbing properties, which reduce the electron cloud density of amino groups, reduce the alkalinity of amino groups, and increase the acidity. Its amino groups can form salts with acids, and can also react with electrophilic reagents such as acyl halides and acid anhydrides to form new amides. And the nitrogen atom in the sulfonamide can participate in the formation of hydrogen bonds, which affects its physical and chemical properties.
If p-chlorobenzene interacts with sulfonamide, due to the structural properties of the two, or nucleophilic substitution may occur. The amino group of sulfonamide is nucleophilic, or the carbon connected to the chlorine atom of p-chlorobenzene is attacked, so that the chlorine leaves to produce new compounds containing the structural fragments of p-chlorobenzene and sulfonamide. This process requires suitable catalysts and reaction conditions, such as base catalysis, to promote the reaction. The properties of the products after the reaction are also determined by the combination of the two and the new structure, or have new acid-base, nucleophilic, electrophilic and other chemical activities, which have potential applications in organic synthesis and drug development.
As for sulfonamides, they contain sulfonyl groups and amino groups. Sulfonyl groups have electron-absorbing properties, which reduce the electron cloud density of amino groups, reduce the alkalinity of amino groups, and increase the acidity. Its amino groups can form salts with acids, and can also react with electrophilic reagents such as acyl halides and acid anhydrides to form new amides. And the nitrogen atom in the sulfonamide can participate in the formation of hydrogen bonds, which affects its physical and chemical properties.
If p-chlorobenzene interacts with sulfonamide, due to the structural properties of the two, or nucleophilic substitution may occur. The amino group of sulfonamide is nucleophilic, or the carbon connected to the chlorine atom of p-chlorobenzene is attacked, so that the chlorine leaves to produce new compounds containing the structural fragments of p-chlorobenzene and sulfonamide. This process requires suitable catalysts and reaction conditions, such as base catalysis, to promote the reaction. The properties of the products after the reaction are also determined by the combination of the two and the new structure, or have new acid-base, nucleophilic, electrophilic and other chemical activities, which have potential applications in organic synthesis and drug development.
What is the production process of P-chlorobenzene Sulfonamide?
To prepare p-chlorobenzenesulfonamide, the process is as follows:
First, p-chlorobenzene is used as the base material, and it is often sulfonated together with fuming sulfuric acid. The two are mixed, and the temperature is controlled at a suitable temperature. If the cap temperature is too high, the side should multiply and the product is impure; if it is too low, the reaction is slow and time-consuming. Generally speaking, the temperature may be controlled between one hundred and twenty degrees Celsius. In this temperature, the sulfonyl group of sulfuric acid (-SO-H) electrophilically attacks the benzene ring of p-chlorobenzene, and through the rearrangement of the electron cloud, p-chlorobenzenesulfonic acid is obtained. The corresponding formula is roughly: P-chlorobenzene + H 2O SO (fuming) → P-chlorobenzenesulfonic acid + H 2O O.
Then, the p-chlorobenzenesulfonic acid interacts with ammonia or ammonium salts to form sulfonamides. Ammonia is often introduced into the solution of p-chlorobenzenesulfonic acid, or ammonium salts such as ammonium carbonate, ammonium sulfate, etc. In this step, the nitrogen atom of ammonia or ammonium root has a lone pair electron, the sulfur atom of the nucleophilic sulfonyl group, and the hydroxyl group is successively added to give p-chlorobenzenesulfonamide. If ammonia is introduced, the formula is about: P-chlorobenzenesulfonic acid + NH 🥰 → P-chlorobenzenesulfonamide + H2O O.
However, in practice, there is a process of refining. Due to the reaction product or containing untreated raw materials, by-products, etc. Refining method, or recrystallization technique. Depending on the solubility of chlorobenzenesulfonamide, the solvent, such as ethanol, water, etc., is selected to keep the mother liquor, while the pure product is precipitated in crystallization. Or the method of column chromatography, according to the adsorption and distribution of p-chlorobenzenesulfonamide and hetero in the stationary phase and the mobile phase, and purify it.
To prepare p-chlorobenzenesulfonamide, the process steps should be carefully controlled and the refining method should be used to obtain high-quality products.
First, p-chlorobenzene is used as the base material, and it is often sulfonated together with fuming sulfuric acid. The two are mixed, and the temperature is controlled at a suitable temperature. If the cap temperature is too high, the side should multiply and the product is impure; if it is too low, the reaction is slow and time-consuming. Generally speaking, the temperature may be controlled between one hundred and twenty degrees Celsius. In this temperature, the sulfonyl group of sulfuric acid (-SO-H) electrophilically attacks the benzene ring of p-chlorobenzene, and through the rearrangement of the electron cloud, p-chlorobenzenesulfonic acid is obtained. The corresponding formula is roughly: P-chlorobenzene + H 2O SO (fuming) → P-chlorobenzenesulfonic acid + H 2O O.
Then, the p-chlorobenzenesulfonic acid interacts with ammonia or ammonium salts to form sulfonamides. Ammonia is often introduced into the solution of p-chlorobenzenesulfonic acid, or ammonium salts such as ammonium carbonate, ammonium sulfate, etc. In this step, the nitrogen atom of ammonia or ammonium root has a lone pair electron, the sulfur atom of the nucleophilic sulfonyl group, and the hydroxyl group is successively added to give p-chlorobenzenesulfonamide. If ammonia is introduced, the formula is about: P-chlorobenzenesulfonic acid + NH 🥰 → P-chlorobenzenesulfonamide + H2O O.
However, in practice, there is a process of refining. Due to the reaction product or containing untreated raw materials, by-products, etc. Refining method, or recrystallization technique. Depending on the solubility of chlorobenzenesulfonamide, the solvent, such as ethanol, water, etc., is selected to keep the mother liquor, while the pure product is precipitated in crystallization. Or the method of column chromatography, according to the adsorption and distribution of p-chlorobenzenesulfonamide and hetero in the stationary phase and the mobile phase, and purify it.
To prepare p-chlorobenzenesulfonamide, the process steps should be carefully controlled and the refining method should be used to obtain high-quality products.
What are the precautions for P-chlorobenzene Sulfonamide during use?
With the reaction of p-chlorobenzene and sulfonamide, many precautions must be made clear during the operation.
The quality of the first raw material, p-chlorobenzene must be pure, and impurities are present, the reaction is off-track, the product is impure, and the quality is difficult to meet the needs. The same is true of sulfonamide, and its purity and properties must be carefully checked before it can be used in accordance with the standard.
The control of reaction conditions is crucial. If the temperature is too high, the reaction will be excessive, side reactions will be plentiful, and the product will be complex and difficult to separate. If it is too low, the reaction will be slow, take a long time, and the yield will be low. Therefore, the temperature must be precisely regulated according to the characteristics of the reaction, and a suitable reaction environment must be set
In addition, the choice of reaction solvent is also exquisite. It should be able to dissolve the raw materials well, promote the smooth progress of the reaction, and do not cause adverse reactions with the reactants and products. At the same time, the boiling point, volatility and other properties of the solvent must also be considered for subsequent separation and purification operations.
The stirring rate should not be underestimated. Moderate stirring can make the reactants fully contact and react evenly, preventing local overheating or the risk of uneven reaction. Too fast or too slow rate is not conducive to the reaction process.
The cleanliness of the reaction equipment is also related to success or failure. Oil and impurities remain on the wall of the vessel, or cause changes in catalytic activity, which affect the reaction effect.
Monitoring the reaction process is indispensable. By means of thin-layer chromatography, gas chromatography and other methods, the degree of reaction can be detected in a timely manner to determine the best reaction endpoint, avoid waste of raw materials, and improve the yield of the product.
After the reaction is completed, the operation of product separation and purification should be done with caution. Choose appropriate methods, such as extraction, distillation, recrystallization, etc., to remove impurities and obtain high-purity products.
These things are all things that should be carefully paid attention to during the reaction of chlorobenzene and sulfonamide. When operating, be careful to make the reaction smooth and achieve the expected results.
The quality of the first raw material, p-chlorobenzene must be pure, and impurities are present, the reaction is off-track, the product is impure, and the quality is difficult to meet the needs. The same is true of sulfonamide, and its purity and properties must be carefully checked before it can be used in accordance with the standard.
The control of reaction conditions is crucial. If the temperature is too high, the reaction will be excessive, side reactions will be plentiful, and the product will be complex and difficult to separate. If it is too low, the reaction will be slow, take a long time, and the yield will be low. Therefore, the temperature must be precisely regulated according to the characteristics of the reaction, and a suitable reaction environment must be set
In addition, the choice of reaction solvent is also exquisite. It should be able to dissolve the raw materials well, promote the smooth progress of the reaction, and do not cause adverse reactions with the reactants and products. At the same time, the boiling point, volatility and other properties of the solvent must also be considered for subsequent separation and purification operations.
The stirring rate should not be underestimated. Moderate stirring can make the reactants fully contact and react evenly, preventing local overheating or the risk of uneven reaction. Too fast or too slow rate is not conducive to the reaction process.
The cleanliness of the reaction equipment is also related to success or failure. Oil and impurities remain on the wall of the vessel, or cause changes in catalytic activity, which affect the reaction effect.
Monitoring the reaction process is indispensable. By means of thin-layer chromatography, gas chromatography and other methods, the degree of reaction can be detected in a timely manner to determine the best reaction endpoint, avoid waste of raw materials, and improve the yield of the product.
After the reaction is completed, the operation of product separation and purification should be done with caution. Choose appropriate methods, such as extraction, distillation, recrystallization, etc., to remove impurities and obtain high-purity products.
These things are all things that should be carefully paid attention to during the reaction of chlorobenzene and sulfonamide. When operating, be careful to make the reaction smooth and achieve the expected results.
What is the market outlook for P-chlorobenzene Sulfonamide?
The market prospects of P-chlorobenzene and sulfonamide are related to many aspects.
P-chlorobenzene is an important raw material for organic synthesis. In the field of medicine, it can be used as an intermediate for antibacterial drugs. Looking at the current booming pharmaceutical industry, the demand for antibacterial drugs is solid. If the research and development of anti-infective drugs continues to advance, P-chlorobenzene has a specific chemical structure and is indispensable for the synthesis of high-efficiency and low-toxicity antibacterial drugs, which provides a solid support for its market.
In the field of pesticides, P-chlorobenzene is also widely used. With people's emphasis on the quality and safety of agricultural products, the development of high-efficiency, low-toxicity and environmentally friendly pesticides is the general trend. P-chlorobenzene can be used to synthesize key intermediates of such pesticides, such as new insecticides, fungicides, etc., so the demand for it in the pesticide industry is expected to grow steadily.
And sulfonamides are widely used. In medicine, many sulfonamides are sulfonamide derivatives with antibacterial and diuretic effects. With the growth of population and the progress of medical level, the demand for sulfonamides may be stable.
In the dye industry, sulfonamides can be used as important intermediates to endow dyes with excellent properties, such as improving dyeing fastness and vividness. Although the current textile printing and dyeing industry is highly competitive, the demand for high-quality dyes has not decreased, and sulfonamides still have market space in this field.
Furthermore, with the continuous innovation of chemical technology, the synthesis process of P-chlorobenzene and sulfonamide may be optimized, the cost is reduced, and the quality is improved, thereby enhancing its market competitiveness and expanding the scope of market application.
In summary, P-chlorobenzene and sulfonamide have considerable market prospects in the pharmaceutical, pesticide, dye and other industries. Although facing competition and technical challenges, with the development of various industries, its demand is expected to grow, and the prospect is quite promising.
P-chlorobenzene is an important raw material for organic synthesis. In the field of medicine, it can be used as an intermediate for antibacterial drugs. Looking at the current booming pharmaceutical industry, the demand for antibacterial drugs is solid. If the research and development of anti-infective drugs continues to advance, P-chlorobenzene has a specific chemical structure and is indispensable for the synthesis of high-efficiency and low-toxicity antibacterial drugs, which provides a solid support for its market.
In the field of pesticides, P-chlorobenzene is also widely used. With people's emphasis on the quality and safety of agricultural products, the development of high-efficiency, low-toxicity and environmentally friendly pesticides is the general trend. P-chlorobenzene can be used to synthesize key intermediates of such pesticides, such as new insecticides, fungicides, etc., so the demand for it in the pesticide industry is expected to grow steadily.
And sulfonamides are widely used. In medicine, many sulfonamides are sulfonamide derivatives with antibacterial and diuretic effects. With the growth of population and the progress of medical level, the demand for sulfonamides may be stable.
In the dye industry, sulfonamides can be used as important intermediates to endow dyes with excellent properties, such as improving dyeing fastness and vividness. Although the current textile printing and dyeing industry is highly competitive, the demand for high-quality dyes has not decreased, and sulfonamides still have market space in this field.
Furthermore, with the continuous innovation of chemical technology, the synthesis process of P-chlorobenzene and sulfonamide may be optimized, the cost is reduced, and the quality is improved, thereby enhancing its market competitiveness and expanding the scope of market application.
In summary, P-chlorobenzene and sulfonamide have considerable market prospects in the pharmaceutical, pesticide, dye and other industries. Although facing competition and technical challenges, with the development of various industries, its demand is expected to grow, and the prospect is quite promising.
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