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P-Chlorobenzenesulfonyl Chloride
Linshang Chemical
|
HS Code |
785425 |
| Chemical Formula | C6H4Cl2O2S |
| Molar Mass | 225.06 g/mol |
| Appearance | Colorless to light yellow liquid |
| Density | 1.49 g/cm³ |
| Boiling Point | 145 - 147 °C (10 mmHg) |
| Melting Point | 27 - 28 °C |
| Solubility In Water | Reacts with water |
| Solubility In Organic Solvents | Soluble in many organic solvents like benzene, toluene |
| Odor | Pungent odor |
| Flash Point | 110 °C |
As an accredited P-Chlorobenzenesulfonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of P - chlorobenzenesulfonyl Chloride packaged in a sealed glass bottle. |
| Storage | P - chlorobenzenesulfonyl chloride should be stored in a cool, dry, well - ventilated area, away from heat sources and direct sunlight. It must be stored separately from oxidizing agents, reducing agents, bases, and water - containing substances. Keep it in a tightly - sealed container to prevent moisture ingress and potential decomposition or reactions. Use appropriate storage cabinets or areas designated for corrosive and reactive chemicals. |
| Shipping | P - chlorobenzenesulfonyl Chloride is a hazardous chemical. It must be shipped in accordance with strict regulations. Use appropriate, well - sealed containers, labeled clearly, and transported by carriers licensed for hazardous materials. |
Competitive P-Chlorobenzenesulfonyl Chloride prices that fit your budget—flexible terms and customized quotes for every order.
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What are the main uses of P-chlorobenzenesulfonyl Chloride?
P-chlorobenzenesulfonyl chloride is also a commonly used reagent in organic synthesis. Its main uses cover the following numbers.
First, it is used in the synthesis of medicine and has many applications. It is often an intermediary for the preparation of various drugs. When synthesizing some antibacterial drugs and anti-inflammatory drugs, p-chlorobenzenesulfonyl chloride can participate in key reaction steps. With its unique chemical properties, it can build a specific structure of drug molecules to impart drug-specific pharmacological activities.
Second, it also plays an important role in the field of pesticide creation. It can be used as a raw material for synthesizing active ingredients of pesticides. Through a series of chemical reactions, it is combined with other compounds to make pesticides, fungicides and other pesticide products to protect crops from insect infestation and protect agricultural harvests.
Third, in the field of materials science, p-chlorobenzenesulfonyl chloride can also play a role. In the process of synthesizing special polymer materials, it can act as a functional monomer. Its introduction can endow polymer materials with special properties, such as improving the solubility and thermal stability of the material, or endowing the material with specific surface activity, etc., thereby meeting the special needs of different fields for material properties.
Fourth, it is also commonly used in the synthesis of dyes. It can be used as a synthetic dye intermediate to react with other compounds containing nitrogen and sulfur to build a color system of dye molecules, so as to obtain dye products with rich colors and excellent properties, which are used in textiles, printing and dyeing industries.
First, it is used in the synthesis of medicine and has many applications. It is often an intermediary for the preparation of various drugs. When synthesizing some antibacterial drugs and anti-inflammatory drugs, p-chlorobenzenesulfonyl chloride can participate in key reaction steps. With its unique chemical properties, it can build a specific structure of drug molecules to impart drug-specific pharmacological activities.
Second, it also plays an important role in the field of pesticide creation. It can be used as a raw material for synthesizing active ingredients of pesticides. Through a series of chemical reactions, it is combined with other compounds to make pesticides, fungicides and other pesticide products to protect crops from insect infestation and protect agricultural harvests.
Third, in the field of materials science, p-chlorobenzenesulfonyl chloride can also play a role. In the process of synthesizing special polymer materials, it can act as a functional monomer. Its introduction can endow polymer materials with special properties, such as improving the solubility and thermal stability of the material, or endowing the material with specific surface activity, etc., thereby meeting the special needs of different fields for material properties.
Fourth, it is also commonly used in the synthesis of dyes. It can be used as a synthetic dye intermediate to react with other compounds containing nitrogen and sulfur to build a color system of dye molecules, so as to obtain dye products with rich colors and excellent properties, which are used in textiles, printing and dyeing industries.
What are the physical properties of P-chlorobenzenesulfonyl Chloride?
P-chlorobenzenesulfonyl chloride is an important compound in organic chemistry. Its physical properties are worth exploring.
Looking at its properties, under normal circumstances, P-chlorobenzenesulfonyl chloride is mostly a colorless to slightly yellow oily liquid with a clear appearance and a specific luster. Its smell has a pungent and special smell. This smell is strong and can spread rapidly in the air, which is noticeable.
When it comes to the melting point, it is about 14 ° C. At this temperature, the substance changes from solid to liquid, showing its phase change. The boiling point is about 251 ° C. When this high temperature is reached, P-chlorobenzenesulfonyl chloride will change from liquid to gas. The density of P-chlorobenzenesulfonyl chloride is also one of its important physical properties, about 1.499g/cm ³, which is higher than the density of water, so if placed in water, it will sink to the bottom. In terms of solubility, it has good solubility in most organic solvents, such as ether, benzene, chloroform, etc., and can dissolve with these organic solvents to form a uniform solution; however, its solubility in water is poor. When mixed with water, it is easy to stratify and mainly remains in the lower layer.
In addition, the volatility of P-chlorobenzenesulfonyl chloride cannot be ignored. Although it is not very volatile, some molecules will still escape into the air under appropriate temperature and ventilation conditions. This property requires special attention during storage and use. In conclusion, the various physical properties are interrelated and affect the application of P-chlorobenzenesulfonyl chloride in chemical synthesis and related fields.
Looking at its properties, under normal circumstances, P-chlorobenzenesulfonyl chloride is mostly a colorless to slightly yellow oily liquid with a clear appearance and a specific luster. Its smell has a pungent and special smell. This smell is strong and can spread rapidly in the air, which is noticeable.
When it comes to the melting point, it is about 14 ° C. At this temperature, the substance changes from solid to liquid, showing its phase change. The boiling point is about 251 ° C. When this high temperature is reached, P-chlorobenzenesulfonyl chloride will change from liquid to gas. The density of P-chlorobenzenesulfonyl chloride is also one of its important physical properties, about 1.499g/cm ³, which is higher than the density of water, so if placed in water, it will sink to the bottom. In terms of solubility, it has good solubility in most organic solvents, such as ether, benzene, chloroform, etc., and can dissolve with these organic solvents to form a uniform solution; however, its solubility in water is poor. When mixed with water, it is easy to stratify and mainly remains in the lower layer.
In addition, the volatility of P-chlorobenzenesulfonyl chloride cannot be ignored. Although it is not very volatile, some molecules will still escape into the air under appropriate temperature and ventilation conditions. This property requires special attention during storage and use. In conclusion, the various physical properties are interrelated and affect the application of P-chlorobenzenesulfonyl chloride in chemical synthesis and related fields.
P-chlorobenzenesulfonyl Chloride chemically stable?
The chemical properties of p-chlorobenzenesulfonyl chloride are not stable. It is active, and in contact with water, it is easy to hydrolyze, resulting in p-chlorobenzenesulfonic acid and hydrogen chloride. Its hydrolysis is like being invaded by water, that is, there is white fog, because hydrogen chloride escapes in the air, and it gathers into fog when exposed to water vapor.
When p-chlorobenzenesulfonyl chloride meets alcohols, it becomes a sulfonate. It reacts especially vigorously in alkali solution, and the hydrolysis speed is complete. It can also react with ammonia or amines to produce sulfonamides. This reaction is often used in organic synthesis to make sulfonamides.
Furthermore, p-chlorobenzenesulfonyl chloride is highly corrosive and can cause injuries to the skin and eyes when it touches. And its volatile gas, pungent and poisonous, enters the lungs and is harmful to breathing.
When stored, it is necessary to avoid water and moisture, and it should be placed in a cool, dry and well-ventilated place. When using it, it is also necessary to strictly abide by the procedures and prepare protective equipment, such as gas masks and protective gloves, to avoid injury to the body and ensure a safe environment. Therefore, the chemical properties of p-chlorobenzenesulfonyl chloride are not stable, so be careful when using it.
When p-chlorobenzenesulfonyl chloride meets alcohols, it becomes a sulfonate. It reacts especially vigorously in alkali solution, and the hydrolysis speed is complete. It can also react with ammonia or amines to produce sulfonamides. This reaction is often used in organic synthesis to make sulfonamides.
Furthermore, p-chlorobenzenesulfonyl chloride is highly corrosive and can cause injuries to the skin and eyes when it touches. And its volatile gas, pungent and poisonous, enters the lungs and is harmful to breathing.
When stored, it is necessary to avoid water and moisture, and it should be placed in a cool, dry and well-ventilated place. When using it, it is also necessary to strictly abide by the procedures and prepare protective equipment, such as gas masks and protective gloves, to avoid injury to the body and ensure a safe environment. Therefore, the chemical properties of p-chlorobenzenesulfonyl chloride are not stable, so be careful when using it.
What are the applications of P-chlorobenzenesulfonyl Chloride in synthesis?
P-chlorobenzenesulfonyl chloride is widely used. In the field of organic synthesis, it is often a key reagent.
First, it can be used to prepare sulfonamide compounds. In this reaction, P-chlorobenzenesulfonyl chloride interacts with amines, and the chlorine atom is replaced by an amino group to obtain sulfonamides. Sulfonamides are of great significance in pharmaceutical chemistry. Many drugs, such as some antibacterial and diuretic agents, contain the structure of sulfonamides. This structure endows the drug with specific pharmacological activities and physicochemical properties, which help it to exert its effect in the body.
Second, P-chlorobenzenesulfonyl chloride can be used to prepare sulfonylureas. It reacts with ureas to form a sulfonylurea structure. Such compounds are commonly used herbicides in agricultural chemistry. They can inhibit the growth of weeds. Due to their specific biological activities, they can affect the physiological processes of weeds, but have little effect on crops. Therefore, they are widely used in field weed control.
Third, P-chlorobenzenesulfonyl chloride is also useful in the preparation of dyes and pigments. The reaction it participates in can introduce specific functional groups, change the structure and properties of molecules, and make the resulting dyes or pigments have specific colors, light resistance, and washable properties. By regulating the reaction conditions and reactants, dyes and pigments that meet different needs can be prepared for textile, coating and other industries.
Fourth, in the multi-step reaction of organic synthesis, P-chlorobenzenesulfonyl chloride is often an important intermediate for constructing complex molecular structures. With its active chlorine atoms, many reactions such as substitution and condensation can occur, gradually building the structure of the target molecule, providing a path for the synthesis of exquisite organic compounds.
First, it can be used to prepare sulfonamide compounds. In this reaction, P-chlorobenzenesulfonyl chloride interacts with amines, and the chlorine atom is replaced by an amino group to obtain sulfonamides. Sulfonamides are of great significance in pharmaceutical chemistry. Many drugs, such as some antibacterial and diuretic agents, contain the structure of sulfonamides. This structure endows the drug with specific pharmacological activities and physicochemical properties, which help it to exert its effect in the body.
Second, P-chlorobenzenesulfonyl chloride can be used to prepare sulfonylureas. It reacts with ureas to form a sulfonylurea structure. Such compounds are commonly used herbicides in agricultural chemistry. They can inhibit the growth of weeds. Due to their specific biological activities, they can affect the physiological processes of weeds, but have little effect on crops. Therefore, they are widely used in field weed control.
Third, P-chlorobenzenesulfonyl chloride is also useful in the preparation of dyes and pigments. The reaction it participates in can introduce specific functional groups, change the structure and properties of molecules, and make the resulting dyes or pigments have specific colors, light resistance, and washable properties. By regulating the reaction conditions and reactants, dyes and pigments that meet different needs can be prepared for textile, coating and other industries.
Fourth, in the multi-step reaction of organic synthesis, P-chlorobenzenesulfonyl chloride is often an important intermediate for constructing complex molecular structures. With its active chlorine atoms, many reactions such as substitution and condensation can occur, gradually building the structure of the target molecule, providing a path for the synthesis of exquisite organic compounds.
What are the production methods of P-chlorobenzenesulfonyl Chloride?
The method of making p-chlorobenzenesulfonyl chloride has been explored by many scholars in the past. One common method is to mix p-chlorobenzenesulfonate with phosphorus pentachloride. The two meet, like the intersection of ancient soldiers, and cause a violent transformation. The hydroxyl group of the sulfonic acid in p-chlorobenzenesulfonate is replaced by the chlorine atom in phosphorus pentachloride, and then becomes the target p-chlorobenzenesulfonyl chloride. When it reacts, phosphorus pentachloride is like a warrior, and it attacks vigorously. The hydroxyl group of the sulfonic acid is like a defeated army. It retreats and combines with other groups of phosphorus to give birth to new compounds.
Furthermore, p-chlorobenzene and chlorosulfonic acid can also be used as raw materials. The benzene ring of p-chlorobenzene is active. When encountering chlorosulfonic acid, the sulfonic acid group in the chlorosulfonic acid is like a keen hunter, precisely falling on the side of the chlorine atom of the counterpart of the benzene ring, forming the intermediate of p-chlorobenzenesulfonic acid. Then, this intermediate reacts with chlorinating agents such as phosphorus trichloride or sulfinyl chloride. The power of the chlorinating agent prompts its conversion, and finally the p-chlorobenzenesulfonic acid chloride is obtained. This process is like a chain of links, which are interlocked step by step, and each step needs to be carefully observed before it can become the product of this chemical industry.
Another method uses p-chlorosulfenol as the starting material. First, p-chlorosulfenol is oxidized to p-chlorosulfonic acid. This Afterwards, it is also treated with a chlorinating agent as mentioned above to form a sulfonyl chloride. All kinds of production methods have their own strengths and weaknesses, all of which depend on the craftsman's careful selection according to actual needs, material preparation, and conditions, in order to get good things.
Furthermore, p-chlorobenzene and chlorosulfonic acid can also be used as raw materials. The benzene ring of p-chlorobenzene is active. When encountering chlorosulfonic acid, the sulfonic acid group in the chlorosulfonic acid is like a keen hunter, precisely falling on the side of the chlorine atom of the counterpart of the benzene ring, forming the intermediate of p-chlorobenzenesulfonic acid. Then, this intermediate reacts with chlorinating agents such as phosphorus trichloride or sulfinyl chloride. The power of the chlorinating agent prompts its conversion, and finally the p-chlorobenzenesulfonic acid chloride is obtained. This process is like a chain of links, which are interlocked step by step, and each step needs to be carefully observed before it can become the product of this chemical industry.
Another method uses p-chlorosulfenol as the starting material. First, p-chlorosulfenol is oxidized to p-chlorosulfonic acid. This Afterwards, it is also treated with a chlorinating agent as mentioned above to form a sulfonyl chloride. All kinds of production methods have their own strengths and weaknesses, all of which depend on the craftsman's careful selection according to actual needs, material preparation, and conditions, in order to get good things.
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