P-Chlorobenzenesulfonyl Chloride Cas:98-60-2
Linshang Chemical
HS Code |
151742 |
Chemical Name | P-Chlorobenzenesulfonyl Chloride |
Cas Number | 98-60-2 |
Molecular Formula | C6H4Cl2O2S |
Molecular Weight | 211.065 g/mol |
Appearance | Colorless to light yellow liquid |
Boiling Point | 145 - 147 °C at 20 mmHg |
Melting Point | 39 - 41 °C |
Density | 1.498 g/cm³ |
Solubility | Insoluble in water, soluble in organic solvents |
Flash Point | 127 °C |
Vapor Pressure | 0.00073 mmHg at 25 °C |
Refractive Index | 1.565 |
As an accredited P-Chlorobenzenesulfonyl Chloride Cas:98-60-2 factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | P - chlorobenzenesulfonyl Chloride (Cas:98 - 60 - 2), 500g in sealed, corrosion - resistant container. |
Storage | P - chlorobenzenesulfonyl chloride (CAS: 98 - 60 - 2) should be stored in a cool, dry, well - ventilated area, away from heat and ignition sources. Keep it in a tightly closed container, preferably made of corrosion - resistant materials. Store it separately from incompatible substances like bases, reducing agents, and moisture - sensitive materials to prevent reactions. |
Shipping | P - chlorobenzenesulfonyl chloride (Cas: 98 - 60 - 2) is a hazardous chemical. Shipping requires proper containment in approved containers, following regulations for corrosive substances, with clear labeling for safe transportation. |
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As a leading P-Chlorobenzenesulfonyl Chloride Cas:98-60-2 supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
First, it is often used as a key intermediate in the field of pharmaceutical synthesis. It can participate in the construction of a variety of drug molecules, and through its active chemical properties, it reacts with other compounds such as substitution and condensation, and then obtains pharmaceutical ingredients with specific pharmacological activities. In the synthesis of some antibacterial drugs and cardiovascular drugs, P-chlorobenzenesulfonyl chloride plays an indispensable role, helping to precisely construct the structure of drug molecules to achieve the expected efficacy.
Second, it also plays an important role in the manufacture of pesticides. It can be used as a starting material or intermediate for the synthesis of a variety of pesticides. After a series of chemical reactions, pesticide products with insecticidal, bactericidal, weeding and other effects can be generated. For example, some high-efficiency and low-toxicity new pesticides are created, and P-chlorobenzenesulfonyl chloride provides a unique structural fragment for them, which helps to improve the activity and selectivity of pesticides and reduce the impact on the environment.
Third, in the dye industry, it can be used to synthesize various types of dyes. By reacting with different organic compounds, dye molecules with specific colors and properties are generated. The dyes involved in the synthesis have bright colors and good fastness. They are widely used in textile, printing and dyeing and other industries to impart rich and colorful colors to fabrics.
Fourth, in the field of organic materials, P-chlorobenzenesulfonyl chloride can be used to prepare special polymer materials. By polymerizing with monomers containing specific functional groups, polymer materials can endow unique properties, such as good thermal stability, mechanical properties, etc., and are used in high-end fields such as aerospace and electronics.
This substance is colorless to slightly yellow liquid at room temperature, and it has a pungent appearance. Its boiling point is quite high, about 255 ° C. This property allows it to maintain a relatively stable state in high temperature environments. In reactions that require higher temperatures, it can effectively participate without causing light volatilization and escape.
The melting point is about 14 ° C. This temperature limit allows it to be converted from solid to liquid at a slightly higher temperature, which is convenient for access and participation in the reaction. The density of
is 1.496g/mL, which is heavier than water. When it involves operations such as liquid-liquid separation, this density characteristic can help determine its position in the system.
In addition, its solubility also has characteristics. It can be soluble in organic solvents such as ether and benzene. This characteristic provides convenience for the selection of suitable reaction media in organic synthesis, which can make the reaction proceed more smoothly in the homogeneous system and is conducive to sufficient contact and reaction between the reactants.
Because of its volatility, during operation, it is necessary to pay attention to safety measures such as ventilation to prevent it from escaping into the air and causing adverse effects on the health and environment of the experimenter. In conclusion, knowing the physical properties of P-chlorobenzenesulfonyl chloride is the key to the proper application of this substance in organic synthesis and other fields.
This substance is quite self-sustaining at room temperature. In case of hot topic or open flame, a crisis will appear. It can decompose violently, causing harmful hydrogen chloride and sulfur dioxide gas to escape, so its stability is greatly reduced in high temperature environments.
In case of water or water vapor, it is also unstable. It can react with it, hydrolyze and deteriorate, which also proves that it is not stable in humid environments.
In the field of organic synthesis, it is often used as a sulfonylating agent to react with alcohols, amines and other compounds. In such reactions, p-chlorobenzenesulfonyl chloride has a high activity. This activity is not only the basis for its application in synthesis, but also reflects from the side that its chemical properties are not extremely stable, and it is easy to undergo chemical changes with other substances.
As for the storage environment, it must be dry, cool and well ventilated to avoid fire, heat sources and water. If it is stored properly, its properties can be relatively stable within a certain period of time; if it is not stored properly, it is easy to deteriorate and the stability is no longer.
In short, the stability of p-chlorobenzenesulfonyl chloride varies according to environmental conditions and the objects it comes into contact with, and it is not absolutely stable.
It is active and easy to react in contact with water, so it must be placed in a dry place to avoid moisture. If stored in a humid place, water comes into contact with P-chlorobenzenesulfonyl chloride, and the hydrolysis changes, causing its quality to be damaged and its efficacy to be greatly reduced.
And this substance is sensitive to heat. Under high temperature, it is easy to decompose, or even has the risk of explosion. The storage temperature should be controlled in a cool environment, away from heat and fire sources, and it can be kept safe.
And P-chlorobenzenesulfonyl chloride is corrosive. In the choice of containers, corrosion-resistant materials, such as glass, specific plastic or metal materials, must be used, and the sealing must be strict to prevent leakage. The risk of leakage not only damages itself, but also endangers the surrounding environment and personal safety.
In addition, the storage place should be well ventilated to make the air smooth. If the ventilation is not smooth, the leakage of gas accumulates, and the concentration gradually increases, which not only increases the risk of explosion, but also harms human health. Inhalation of this gas can cause damage to the respiratory tract, eyes and other parts.
Repeat, the place of storage must be clearly marked, and the warnings such as "P-chlorobenzenesulfonyl chloride" and "corrosive" and "flammable" should be clear to the handler at a glance. When operating, be extra cautious.
In general, when storing P-chlorobenzenesulfonyl chloride, dry, cool, sealed, ventilated and clearly marked must be carefully paid attention to to to ensure its safety and ready for use.
In the past, the production of sulfonyl chlorides often started with the corresponding aromatic hydrocarbons. To obtain p-chlorobenzenesulfonyl chloride, take p-chlorobenzene as the group. In this step, the benzene ring of p-chlorobenzene is combined with the sulfonic acid group in the sulfuric acid to produce p-chlorobenzenesulfonic acid.
After sulfonation, take out the product p-chlorobenzenesulfonic acid, re-enter the new kettle, and blend it with phosphorus pentachloride. Heating at a moderate temperature, the two respond. The chlorine atom in phosphorus pentachloride replaces the hydroxyl group in p-chlorobenzenesulfonic acid, and then the p-chlorobenzenesulfonyl chloride is obtained. It should be completed by distillation, fractional distillation, and impurity removal and purification to obtain pure p-chlorobenzenesulfonyl chloride.
Or there are other methods to directly respond to p-chlorobenzene and chlorosulfonic acid. In a closed vessel, with moderate temperature control, the combination of the two can also obtain p-chlorobenzenesulfonyl chloride. Although the principles of these two methods are slightly different, they are all based on the rules of chemical changes, and the ancient process ideas can be used to form this compound.

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