P-Chlorobromobenzene

Linshang Chemical

Specifications

HS Code

717597

Chemical Formula C6H4BrCl
Molar Mass 191.45 g/mol
Appearance Colorless to pale yellow liquid
Density 1.59 g/cm³ at 25 °C
Boiling Point 194 - 196 °C
Melting Point −16 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Odor Aromatic odor
Flash Point 79 °C
Vapor Pressure 0.35 mmHg at 25 °C

As an accredited P-Chlorobromobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing P - chlorobromobenzene in 1 - kg bottles, well - sealed for chemical storage.
Storage P - chlorobromobenzene should be stored in a cool, well - ventilated area away from heat and ignition sources. Keep it in a tightly - sealed container to prevent vapor leakage. Since it is an organic compound, store it separately from oxidizing agents. Avoid exposure to sunlight as it may initiate unwanted reactions. Regularly check storage conditions to ensure safety.
Shipping P - chlorobromobenzene should be shipped in well - sealed containers, following regulations for hazardous chemicals. Ensure proper labeling indicating its nature. Ship via carriers experienced in handling such substances to avoid spillage and ensure safe transit.
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P-Chlorobromobenzene P-Chlorobromobenzene
General Information
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Frequently Asked Questions

As a leading P-Chlorobromobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the chemical structure of P-chlorobromobenzene?
P-chlorobromobenzene is also an organic compound. In its molecular structure, the benzene ring is a six-membered ring structure, which is formed by the connection of six carbon atoms with covalent bonds and is a plane regular hexagon. There are two hydrogen atoms on the benzene ring that are replaced. One is the chlorine atom (Chlorine atom) and the other is the bromine atom (Bromine atom). The two are in the para-position on the benzene ring, that is, the carbon atoms connected to the two are separated by two carbon atoms on the benzene ring. This structure makes P-chlorobromobenzene have specific physical and chemical properties. Because it contains halogen atoms, it can participate in many organic reactions, such as nucleophilic substitution reactions. And the conjugation system of the benzene ring affects the activity of the halogen atom, which in turn affects its reactivity and selectivity. The structure of this compound lays the foundation for its chemical behavior and application, and is of great significance in the fields of organic synthesis and medicinal chemistry.
What are the physical properties of P-chlorobromobenzene?
P-chlorobromobenzene is also an organic compound. It has unique physical properties, which are described in detail by you today.
First of all, its appearance, at room temperature, P-chlorobromobenzene is colorless to light yellow liquid, clear and has a special aromatic odor. Looking at it, the luster is faint, as if hidden in the rhyme.
Describe its melting point and boiling point. The melting point is about -16 ° C. When the temperature drops to this temperature, the substance gradually solidifies. The boiling point is around 196 ° C. When it rises to Swain, it melts gas and boils. The nature of this melting boiling point is crucial in chemical operations such as separation and purification.
Furthermore, in terms of its solubility. P-chlorobromobenzene is insoluble in water, but it can be miscible in many organic solvents, such as ethanol, ether, benzene, etc. This property makes it an excellent solvent in the field of organic synthesis, and it is also convenient to participate in various chemical changes in the reaction system.
The density of the compound is about 1.57 g/cm ³, which is heavier than water. If it is co-located with water, it will sink in the bottom of the water, and the stratification is clear. This property is also the basis for identification and separation.
The relative density of the vapor of P-chlorobromobenzene is greater than that of air. If it leaks in the chamber, the steam is easy to polymerize in low places, which is necessary for safety precautions and cannot be ignored.
Its physical properties are such that it functions in various fields such as chemical engineering, medicine, materials, etc. It is actually one of the key aspects of organic chemistry.
What are the main uses of P-chlorobromobenzene?
P-chlorobromobenzene is also an organic compound. Its main uses are quite extensive, and it has made a lot of contributions in the chemical industry.
It is the key intermediate for the synthesis of many drugs. The way of medicine is related to people's livelihood. When many drugs are synthesized, P-chlorobrobenzene participates in it, and through delicate reactions, it is synthesized into a good medicine for curing and saving people. Because of its unique structure, it can give specific activity and function to drug molecules, which is crucial in the process of drug development.
Furthermore, it also has important functions in the field of materials science. In the synthesis of special polymer materials, P-chlorobromobenzene can be used as a starting material. By means of chemical methods, its structures can be connected and combined to form polymer materials with special properties. These materials may have excellent mechanical properties, or excellent heat resistance and chemical corrosion resistance, and are widely used in frontier fields such as aerospace, electronics and electrical appliances.
In addition, P-chlorobrobenzene is also indispensable in the preparation of fine chemicals. For example, the synthesis of certain high-performance dyes, fragrances and other fine chemicals is often based on it. Through ingenious chemical reaction steps, these fine chemicals are endowed with unique color, aroma and stability to meet people's needs in improving quality of life.
In summary, although P-chlorobromobenzene is an organic compound, it plays a pivotal role in many fields such as medicine, materials, and fine chemicals, promoting the development and progress of various fields.
What are the preparation methods of P-chlorobromobenzene?
To make p-chlorobenzene, there are two methods. First, start with benzene and brominate it first. Take an appropriate amount of benzene, put it in a flask, add bromine and iron powder, this is the catalyst for bromination. Mixing the two, warm, there is bromobenzene. The reverse is as follows:
\ (C_ {6} H_ {6} + Br_ {2}\ xrightarrow {Fe} C_ {6} H_ {5} Br + HBr\)
to obtain bromobenzene, and then chlorinate it. Add chlorine and a catalyst to bromobenzene, such as ferric chloride, and heat up to get p-chlorobenzene. On the contrary, although the target can be obtained, the selectivity of the site is not very good, or there are ortho-isomers, so it must be refined later.
Second, p-chloroaniline is the beginning. First, p-chloroaniline is blended with hydrobromic acid and sodium nitrite, and at low temperature, it is formed into diazonium salt. The reverse is as follows:
\ (C_ {6} H_ {4} ClNH_ {2} + HNO_ {2} + HBr\ xrightarrow {0 - 5 ^ {\ circ} C} C_ {6} H_ {4} ClN_ {2} Br + 2H_ {2} O\)
to form a diazonium salt, after adding hypophosphoric acid, the diazonium group is hydrogenated, and then p-chlorobromobenzene is obtained. The choice of this route is good, there are few by-products, and the conditions are easy to control, but the raw materials are not easily available for chloroaniline, and the cost is high. In summary, both have advantages and disadvantages. When choosing the method, it depends on the factors such as raw materials, cost, yield, and purity.
P-chlorobromobenzene What are the precautions during storage and transportation?
P-chlorobromobenzene is also an organic compound. When storing and transporting, there are several urgent things to pay attention to.
The first thing to bear the brunt is the storage environment. This substance should be placed in a cool, dry and well-ventilated place. Cover because of its certain chemical activity, if it is exposed to high temperature, humidity, or causes chemical reactions, it will damage its quality. As "Tiangong Kaiwu" said, "Everything has its own nature, and it will exist if it goes with it, and it will die if it goes against it. According to the properties of P-chlorobrobenzene, choose a suitable storage place to ensure its stability. And keep away from fire, heat sources, because it encounters open flames, hot topics or risks burning.
Second rule, the packaging must be sealed when storing. If P-chlorobromobenzene is exposed to the air, or reacts with the ingredients in the air. Tight packaging, like the solid of a city, can resist external intrusion. "Tiangong Kaiwu" says "strengthen the outside to prevent internal damage". The packaging is firm and sealed, and can protect P-chlorobromobenzene from external substances.
When transporting, it should not be ignored. It needs to be loaded in containers that meet safety standards to ensure that there is no risk of leakage during transportation. The escort should be familiar with its characteristics and emergency methods, and can respond quickly in case of emergencies. If sailing on a river, the shipman must know the nature of water and the art of avoiding danger. Transportation vehicles should also be kept away from fire sources, heat sources and oxidants to prevent accidents.
In addition, the place of storage and transportation should be equipped with corresponding emergency treatment equipment and suitable containment materials. In case of leakage, it can be dealt with immediately to avoid greater harm. This is also as advocated in "Tiangong Kaiwu".
What is the chemical structure of P-chlorobromobenzene?
P-chlorobromobenzene is also an organic compound. In its chemical structure, the benzene ring is a hexamembered ring structure, and the carbons on the ring are connected by conjugated double bonds, which has special stability. In the counterposition of the benzene ring, a chlorine atom and a bromine atom are respectively connected. Both chlorine and bromine atoms are halogen elements, which have considerable electronegativity, which can change the electron cloud density of the benzene ring. This structure endows P-chlorobrobenzene with unique physical and chemical properties. Due to the presence of halogen atoms, reactions such as nucleophilic substitution can occur. In the field of organic synthesis, it is often used as an intermediate to prepare more complex organic compounds. Due to the particularity of its structure, it has potential application value in many fields such as medicinal chemistry and materials science.
What are the physical properties of P-chlorobromobenzene?
P-chlorobromobenzene is also an organic compound. It has special physical properties and can be studied in detail.
Looking at its properties, under normal circumstances, P-chlorobromobenzene is a colorless to light yellow liquid, transparent, and has a special odor. Its unique smell, although not pungent, is also one of its characteristics.
As for the melting point, the melting point is about -16.6 ° C, and the boiling point is 196.2 ° C. This melting point makes it appear in different physical states within a specific temperature range. When the temperature is lower than -16.6 ° C, it condenses into a solid state; when it is higher than 196.2 ° C, it turns into a gaseous state and a liquid state at room temperature. This is its physical state in common environments.
Furthermore, density is also an important physical property. Its density is heavier than water, about 1.594 g/cm ³, so if mixed with water, P-chlorobrobenzene will sink to the bottom of the water.
In terms of solubility, P-chlorobrobenzene is insoluble in water, but soluble in many organic solvents, such as ethanol, ether, benzene, etc. This difference in solubility is due to the difference in its molecular structure and the forces between water molecules and organic solvent molecules.
In addition, P-chlorobromobenzene has relatively low volatility and is not easy to evaporate quickly into the air. However, in an environment with poor ventilation and high temperature, some volatilization may still be possible. Its vapor pressure is relatively small at room temperature, which also affects its volatilization degree.
The physical properties of P-chlorobromobenzene are of great significance in the fields of organic synthesis and chemical production, and are related to the way it is stored, transported and used.
What are the main uses of P-chlorobromobenzene?
P-chlorobromobenzene, or p-chlorobromobenzene, has a wide range of main uses. In the field of organic synthesis, it is often used as a key intermediate. For example, when creating drugs, its structure can be ingeniously introduced through specific chemical reactions to build molecular structures with unique pharmacological activities. Like some drugs for the treatment of cardiovascular diseases, p-chlorobromobenzene is involved in the synthesis step.
It also plays an important role in the field of materials science. In the process of preparing certain high-performance materials, such as materials with special electrical and optical properties, p-chlorobromobenzene can be used as a basic raw material to generate polymers or composites with specific functions through carefully designed reaction routes, so as to meet the strict requirements of special materials in the fields of electronic devices, optical instruments, etc.
In the dye industry, p-chlorobromobenzene is also indispensable. It can be used as an important starting material for the synthesis of various dyes. After a series of reactions, bright-colored and stable dyes can be obtained, which are widely used in textiles, printing and dyeing and other industries to give fabrics a rich and colorful color.
Overall, p-chlorobromobenzene occupies an important position in many fields such as organic synthesis, materials science, and dye industry, and plays a key role in promoting the development of related industries.
What are P-chlorobromobenzene synthesis methods?
P-chlorobromobenzene is also an organic compound. There are many ways to synthesize it, and now I am here for you.
First, start with benzene. First, benzene and bromine are catalyzed by iron bromide to undergo an electrophilic substitution reaction to obtain bromobenzene. In this reaction, bromine ions are induced by catalysts to become active electrophilic reagents, attack the benzene ring electron cloud, cause bromine atoms to enter the benzene ring, and obtain bromobenzene. Then, bromobenzene and chlorine are subjected to free radical substitution reactions under light or high temperature conditions. At this time, light or high temperature makes chlorine molecules split into chlorine radicals, and bromobenzene side chain hydrogen atoms are taken to form benzyl radicals, which are then combined with chlorine radicals to obtain P-chlorobromobenzene.
Second, starting from aniline. Aniline first reacts with acetyl chloride to form acetaniline, which is a protective amino group. Later, acetaniline reacts with bromine in acetic acid. Because the positioning effect of the amino group after acetylation becomes weaker, the bromine atom mainly enters the para-position to obtain p-bromoacetaniline. Then hydrolysis of p-bromoacetaniline with hydrochloric acid restores the amino group. Finally, the amino group is changed into a diazo salt by diazotization reaction, and the diazo group is replaced by a chlorine atom to obtain P-chlorobromobenzene.
Third, p-chlorophenylboronic acid and bromoaromatic hydrocarbons are used as raw materials. In the presence of palladium catalyst, Suzuki coupling reaction is performed. The boron atom of p-chlorophenylboronic acid is coupled with the bromine atom of bromoaromatic hydrocarbons under palladium catalysis to form a carbon-carbon bond to obtain P-chlorobromobenzene. This method has mild conditions and good selectivity, and is commonly used in organic synthesis.
This number method has its own advantages and disadvantages, depending on the actual required raw materials, conditions and yield factors, and can be selected and used.
P-chlorobromobenzene what are the precautions during storage and transportation?
P-chlorobromobenzene is an organic compound. When storing and transporting, many things need to be paid attention to.
First words storage. Because of its certain chemical activity, it should be placed in a cool, dry and well-ventilated place. Avoid open flames and hot topics to prevent the risk of fire and explosion. In case of high temperature environment, P-chlorobromobenzene may change its chemical properties due to heat, causing adverse consequences. And should be stored separately with oxidants, strong bases and other substances, because P-chlorobromobenzene and them are prone to chemical reactions, causing deterioration or danger.
Second on transportation. When transporting, make sure that the container is well sealed and there is no risk of leakage. If there is a leak, P-chlorobromobenzene escapes, which not only pollutes the environment, but also is harmful to surrounding organisms. Transportation vehicles must also be equipped with corresponding fire protection and emergency treatment equipment to prepare for emergencies. Drivers and escorts should be familiar with the characteristics and emergency treatment methods of P-chlorobromobenzene, and drive cautiously on the way to avoid violent vibrations and collisions, so as to avoid material leakage caused by damage to the container.
Furthermore, whether it is storage or transportation, it is necessary to strictly abide by relevant regulations and standards. Make a good mark to clearly indicate the nature, hazards and emergency treatment measures of P-chlorobromobenzene, so that contacts can see at a glance and take appropriate countermeasures at the first time. Only in this way can we ensure the safety of P-chlorobromobenzene during storage and transportation, avoid accidents, and protect the safety of people, the environment and property.