P-Chloronitrobenzene
Linshang Chemical
HS Code |
639446 |
Chemical Formula | C6H4ClNO2 |
Molar Mass | 157.55 g/mol |
Appearance | Yellowish - green crystals |
Odor | Pungent odor |
Melting Point | 83 - 84 °C |
Boiling Point | 242 °C |
Density | 1.520 g/cm³ (at 20 °C) |
Solubility In Water | Insoluble in water |
Solubility In Organic Solvents | Soluble in ethanol, ether, benzene |
Flash Point | 127 °C |
Vapor Pressure | 1.33 Pa at 20 °C |
Stability | Stable under normal conditions |
As an accredited P-Chloronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | P - chloronitrobenzene: 500g packed in a sealed, corrosion - resistant plastic bottle. |
Storage | P - chloronitrobenzene should be stored in a cool, dry, well - ventilated area, away from sources of ignition. Keep it in a tightly closed container to prevent leakage. Store separately from oxidizing agents, reducing agents, and other incompatible substances. Ensure proper labeling for easy identification and follow safety regulations to avoid any potential hazards. |
Shipping | P - chloronitrobenzene is shipped in tightly sealed containers, often in bulk or drums. It must comply with strict hazardous chemical shipping regulations to prevent spills and ensure safe transport due to its potential risks. |
Competitive P-Chloronitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading P-Chloronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
Looking at its color, at room temperature, it is a light yellow crystalline shape, delicate and with a specific shape. Its taste and smell have a special smell. Although it is not pungent and intolerable, it is also different from the ordinary smell and can be perceived by humans.
As for its melting point, the melting point is about 83 ° C. At this temperature, the solid p-chloronitrobenzene begins to melt into a liquid state. The boiling point is about 235 ° C. At this high temperature, it will change from liquid to gaseous state.
Furthermore, its solubility is also an important physical property. In water, p-chloronitrobenzene has very little solubility and is almost insoluble. Due to the large difference in the hydrogen bonds between water molecules and the forces between p-chloronitrobenzene molecules, the two are difficult to dissolve. However, in organic solvents such as ethanol and ether, its solubility is better, because there are similarities between organic solvents and p-chloronitrobenzene molecules, and they can be miscible with each other.
And its density is slightly larger than that of water, so when placed in water, p-chloronitrobenzene will sink to the bottom. This is an important physical property of p-chloronitrobenzene.
First of all, its chemical activity. On the benzene ring, both the chlorine atom and the nitro group have the effect of electron-absorbing. The nitro group is a strong electron-absorbing group, which greatly reduces the electron cloud density of the benzene ring, causing the activity of the electrophilic substitution reaction of the benzene ring to be greatly reduced. The activity of the nucleophilic substitution reaction is increased. Due to the presence of nitro groups, the carbon atoms of the benzene ring are more vulnerable to attack by nucleophilic reagents. For example, if a nucleophilic reagent such as hydroxide ion attacks, it can replace the chlorine atom to generate p-nitrophenol.
Due to the conjugation effect, the nitro group and the benzene ring form a conjugated system, and the electrons are delocalized, which reduces the molecular energy and enhances the stability. However, it can still participate in a variety of chemical reactions. Due to the influence of substituents, the electron cloud density at the check point of the benzene ring part changes, and the reactivity is different.
Furthermore, the physical properties of P-chloronitrobenzene also affect its chemical behavior. It is mostly solid at room temperature, with a certain melting point and boiling point. It is insoluble in water, but easily soluble in organic solvents. This property is crucial for the operation and separation of organic synthesis reactions. Because of its solubility, it can be fully contacted with other reactants in suitable organic solvents, and then the reaction occurs smoothly.
P-chloronitrobenzene has unique chemical properties due to the interaction between chlorine atoms and nitro groups in its structure. It has important applications in organic synthesis, material preparation and other fields, and is an important object of organic chemistry research.
Furthermore, it also has important functions in medicine. It is a key intermediate for the synthesis of many drugs. After a series of reactions, it can be used to produce drugs that have curative effects on diseases and help human health.
It is also commonly used in the dye industry. Using this as a raw material, dyes with rich colors and excellent properties can be synthesized for fabric dyeing, making the fabric color gorgeous and lasting.
In addition, P-chloronitrobenzene also plays a role in industrial fields such as rubber additives and engineering plastics. It can provide specific performance additives for rubber to enhance rubber durability; it can participate in reactions in the synthesis of engineering plastics, improve plastic properties, and meet different industrial needs. In short, P-chloronitrobenzene is essential in many fields of modern industry and promotes the development of various industries.
Then, the chlorobenzene is reacted with a mixed acid (a mixture of nitric acid and sulfuric acid). Sulfuric acid is the catalyst and dehydrating agent, and nitric acid is the nitrifying agent. In this reaction, a nitro group (NO 2) replaces the hydrogen atom on the chlorobenzene ring. Since the chlorine atom is an ortho-para-localized group, the nitro group mainly replaces its para-hydrogen, resulting in p-
Specifically, in the reactor, add an appropriate amount of chlorobenzene, control the temperature moderately, slowly inject mixed acid into it, and constantly stir to ensure that the reaction is uniform. After the reaction is completed, the product is separated and purified, such as distillation, crystallization, etc., to obtain pure p-chloronitrobenzene. This process is relatively simple and has a high yield, so it is a commonly used method for industrial production of p-chloronitrobenzene.
The first one is related to the storage environment. Its properties are toxic and have certain chemical activity. It should be stored in a cool and ventilated warehouse. Avoiding fire and heat is essential, and it is easy to cause danger when heated. The temperature of the warehouse should be controlled within an appropriate range. If it is too high, the molecular activity will increase, or chemical reactions will be triggered, such as decomposition and combustion. And it must be kept away from fire and heat sources. Fireworks are strictly prohibited to prevent accidental ignition.
Second, the packaging for storage should not be neglected. It must be well sealed to prevent leakage. Because it is toxic, once it leaks, it escapes in the air, and it will damage health and even endanger life; if it penetrates into soil and water, it will also cause environmental pollution. Packaging materials should have anti-corrosion, pressure resistance and other characteristics, and adapt to the chemical properties of p-chloronitrobenzene.
Furthermore, when transporting, there are also many precautions. Transportation vehicles must undergo special inspections to ensure that there are no hidden dangers of leakage. Escort personnel must have professional knowledge and be familiar with emergency response methods. During transportation, protect against sun exposure and rain, and increase their temperature due to sun exposure. Rain may cause damage to packaging and material reactions. Do not mix with oxidants, edible chemicals, etc. Due to its active chemical properties, it encounters with oxidants, or has a violent oxidation reaction, causing combustion and explosion; mix with edible chemicals, and may cause pollution.
In addition, the storage and transportation places should be equipped with corresponding fire and emergency equipment. Such as fire extinguishers, in case of fire; leakage emergency treatment equipment, so as to respond to leakage accidents in a timely manner and reduce hazards. And the place should be clearly marked with warning signs, so that personnel are aware of its danger. In this way, the storage and transportation of p-chloronitrobenzene can be guaranteed to be safe and avoid disasters.
First, it can be used to make dyes. The production of dyes requires a variety of intermediates. P-chloronitrobenzene can be converted into dye components with specific structures through various reactions. For example, through reduction and other steps, the corresponding amines can be obtained, and then combined with other reagents to form colorful dyes for use in fabric dyeing and other industries.
Second, it is also important for pharmaceutical synthesis. Pharmaceutical preparation depends on fine organic synthesis. With its unique structure, P-chloronitrobenzene can be introduced into drug molecules, either to change drug activity or to optimize the solubility of drugs, etc., to help create new drugs.
Third, it is also common in the field of pesticides. After chemical modification, it can become an active ingredient of pesticides, which has the effect of preventing crop diseases and pests, protecting the growth of crops in farmland and ensuring the harvest of food. Due to the characteristics of chlorine atoms and nitro groups on the benzene ring, it can participate in many reactions such as nucleophilic substitution, providing diverse possibilities for organic synthesis. It is a key position in the chemical industry chain and has attracted many chemical workers to study it to expand its use and increase its efficiency. It has made great contributions to the progress of industry, agriculture and medicine.
Looking at its appearance, it is a light yellow needle-like crystal at room temperature, like a fine needle, arranged in an orderly manner, and has a unique luster. It presents a faint yellowish color, which seems to contain a unique chemical mystery.
On its melting point, it is about 83 ° C. When the temperature gradually rises, the compound slowly converts from the solid state to the liquid state, just like ice when heated and melts, from a solid state to a flexible liquid. This is one of the key temperatures for the great transformation of its physical properties.
As for the boiling point, it is about 235 ° C. At this temperature, the molecular movement of the substance is more intense, rising from the liquid state to the gaseous state, just like the transpiration of clouds and mist, breaking away from the shackles of the liquid state and diffusing in space.
The density of P-chloronitrobenzene is 1.520g/cm ³, which is heavier than water. If placed in water, it will sink to the bottom because its molecules are closely arranged and the mass per unit volume is greater than that of water.
Its solubility is also an important property. In water, P-chloronitrobenzene is insoluble, just like oil floating on the water surface, and the two are difficult to blend. This is due to the difference in molecular polarity. However, in organic solvents, such as ethanol, ether, etc., it is soluble, just like a wanderer returning home. It fits with the molecules of organic solvents and blends with each other, showing good solubility.
And because of its certain volatility, although the volatilization rate is not extremely fast, it will slowly emit in the air at a suitable temperature and environment, making the surrounding space permeated with its unique smell, which is also a manifestation of its physical properties.
In the electrophilic substitution reaction, the nitro group is the meta-localization group, which decreases the electron cloud density of the benzene ring, and the electrophilic substitution reaction is more difficult to occur than that of benzene Due to the electron-absorbing conjugation effect and induction effect of nitro, the density of the electron cloud in the ortho and para-position decreases more, while the interpotential decreases less, so the electrophilic reagents are easy to attack the interpotential.
In addition, P-chloronitrobenzene has a certain stability and can exist stably at room temperature and pressure. However, in the case of strong reducing agents, the nitro group can be reduced and converted into an amino group to obtain P-chloroaniline.
In addition, P-chloronitrobenzene has a wide range of uses in the field of organic synthesis, and can be used as an intermediate for the synthesis of many drugs, dyes, pesticides, etc. Because it has the activity of both chlorine atoms and nitro groups, it can introduce various functional groups through different reactions to construct complex organic molecular structures.
One is the nitrification method. First take chlorobenzene as raw material, put it into the reactor, and introduce sulfuric acid and nitric acid as mixed acids. The two react in the kettle, nitric acid acts as a nitrifying agent, and sulfuric acid promotes the reaction and has the effect of dehydration. Control the reaction temperature, do not make it too high, too high will easily produce side reactions, resulting in impure products; nor too low, too low will slow the reaction. After the reaction is completed, the product can be separated and purified to obtain P-chloronitrobenzene. This process is mature, but the mixed acid is highly corrosive, which requires strict equipment, and the waste acid produced needs to be properly handled to avoid polluting the environment.
The second is the chlorination method. Take nitrobenzene as the starting material, place it in the chlorination reaction device, add a catalyst, and pass chlorine gas. Chlorine and nitrobenzene react catalytically to form P-chloronitrobenzene. During the reaction, the choice of catalyst is the most important, which can change the rate of chemical reaction and make the reaction proceed efficiently. The reaction conditions also need to be precisely controlled, such as temperature, pressure, and the rate of chlorine gas. At the end of the reaction, the product also needs to be separated and refined. The raw material of this route is nitrobenzene, which is easy to buy, and there are relatively few side reactions. However, chlorine gas is toxic. The production process needs to be strictly controlled for safety to prevent the risk of chlorine gas leakage.
First of all, storage, this substance should be placed in a cool and ventilated warehouse. Because it is easy to decompose when heated, under high temperature, or dangerous, the temperature of the warehouse should be controlled within an appropriate range. And it must be kept away from fire and heat sources to prevent the disaster of explosion. The lighting, ventilation and other facilities of the warehouse should be explosion-proof, and the electrical equipment must also meet the explosion-proof requirements to avoid disasters caused by electrical sparks.
In addition, P-chloronitrobenzene should be stored separately from oxidizing agents, reducing agents, alkalis, etc., and must not be mixed. Due to its lively chemical properties, it is dangerous to encounter various substances or have a violent chemical reaction. The storage place should be equipped with suitable materials to contain the leakage, in case of leakage, and can be disposed of in time to avoid greater harm.
As for transportation, make sure that the container is well sealed before transportation, and there is no risk of leakage. The transportation vehicle must be equipped with the corresponding variety and quantity of fire protection equipment and leakage emergency treatment equipment. During driving, it should be protected from exposure to the sun, rain and high temperature. When road transportation, it should be driven according to the specified route, and do not stop in residential areas and densely populated areas. When rail transportation, there are also strict regulations, and it is strictly forbidden to slip.
During handling, the operator must wear appropriate protective equipment, such as gas masks, rubber gloves, etc., and handle it lightly. Do not collide or drag to avoid material leakage caused by damage to the container. In short, in the storage and transportation of P-chloronitrobenzene, it is necessary to be careful and follow the regulations to ensure safety.

Scan to WhatsApp