P-Nitrosochlorobenzene

Linshang Chemical

Specifications

HS Code

876980

Chemical Formula C6H4ClNO
Molar Mass 143.55 g/mol
Appearance Yellow - green crystals
Melting Point 38 - 40 °C
Boiling Point 207 - 208 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in benzene, ether, etc.
Odor Pungent
Density 1.368 g/cm³
Stability Unstable, decomposes on exposure to light and heat
Hazard Toxic, harmful if swallowed, inhaled or in contact with skin

As an accredited P-Nitrosochlorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1 kg of P - nitrosochlorobenzene packaged in a tightly - sealed chemical - grade container.
Storage P - nitrosochlorobenzene should be stored in a cool, dry, well - ventilated area, away from heat and ignition sources. Keep it in a tightly closed container to prevent contact with air and moisture, which could cause decomposition. Store it separately from oxidizing agents and reducing agents to avoid potentially hazardous reactions.
Shipping P - nitrosochlorobenzene is a hazardous chemical. Shipping requires compliance with strict regulations. It must be properly packaged in corrosion - resistant containers, labeled clearly, and transported by carriers licensed for hazardous materials.
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P-Nitrosochlorobenzene P-Nitrosochlorobenzene
General Information
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Frequently Asked Questions

As a leading P-Nitrosochlorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the chemistry of P-nitrosochlorobenzene?
P-nitrosochlorobenzene is an organic compound with unique chemical properties. Its molecules contain nitro and chlorine atoms, and this structure endows many properties.
In terms of reactivity, the nitro group on the benzene ring is an electron-absorbing group, which reduces the electron cloud density of the benzene ring and the activity of electrophilic substitution. Although the electron cloud density of the adjacent para-position of the chlorine atom is relatively high, the electrophilic reagents can still attack under certain conditions. At the same time, the nitro group can make the benzene ring more prone to nucleophilic substitution because it can stabilize the reaction intermediate.
P-nitrosochlorobenzene has a certain polarity. Due to the difference in electronegativity between the nitro group and the chlorine atom, the molecular dipole moment is not zero, and this polarity affects its solubility and intermolecular forces The solubility in organic solvents is usually better than that of water, because the molecules and organic solvents can form similar intermolecular forces.
In terms of thermal stability, P - nitrosochlorobenzene is heated or decomposed. Due to the connection of nitro and chlorine atoms to the benzene ring, the chemical bond may break at high temperature, triggering complex reactions, forming nitrogen oxides, hydrogen chloride and other products.
And P - nitrosochlorobenzene has certain toxicity. The presence of nitro and chlorine atoms may interfere with the normal biochemical reactions in organisms. Contact or ingestion may cause health risks. Careful protection is required during operation.
In summary, the chemical properties of P-nitrosochlorobenzene are determined by its structure, and the properties of reactivity, polarity, thermal stability and toxicity need to be considered in the fields of organic synthesis and materials science.
What are the main uses of P-nitrosochlorobenzene?
P-nitrosochlorobenzene, that is, p-nitroso chlorobenzene, has a wide range of uses. In the dye industry, it is an intermediate for the preparation of a variety of important dyes. Due to its special structure, it can undergo a series of chemical reactions to construct various dye molecules with bright colors and excellent properties, so that fabrics and other materials can obtain rich colors.
In the field of pharmaceutical synthesis, p-nitroso chlorobenzene also plays a key role. It can be used as a starting material or a key intermediate to participate in the synthesis of many drug molecules. With its unique chemical activity, it can introduce specific functional groups to help build complex drug structures, providing the possibility for the development of new drugs.
In the field of organic synthetic chemistry research, it is often used as a reaction reagent and intermediate. Due to the activity of nitroso and chlorine atoms, it can participate in various reactions such as nucleophilic substitution and electrophilic addition, which help chemists construct complex organic molecular structures, expand the methods and strategies of organic synthesis, and promote the development of organic chemistry.
In addition, in the field of materials science, p-nitroso chlorobenzene can be chemically modified and transformed to prepare functional materials with special properties, such as some optoelectronic materials, which contribute to the innovative development of materials science.
What is P-nitrosochlorobenzene synthesis method?
To prepare p-nitroso chlorobenzene, first take chlorobenzene and place it in a reactor. Dissolve it in an appropriate solvent, often choose an inert organic solvent, such as dichloromethane, which can disperse the reactants uniformly and facilitate the reaction.
times, cool the reaction system to a suitable low temperature, about 0 ° C to 5 ° C. Because the reaction is exothermic, low temperature can help control the temperature, make the reaction smooth and avoid side reactions.
After that, slowly add a nitrosation reagent, such as a mixture of sodium nitrite and hydrochloric acid. Add time at a constant speed and slowly, stirring while adding, so that the reagent is fully in contact with chlorobenzene. Sodium nitrite interacts with hydrochloric acid to produce nitrous acid immediately. Nitrous acid quickly reacts with chlorobenzene for electrophilic substitution. Nitroso groups are introduced into the para-benzene ring to obtain p-nitroso chlorobenzene.
During the reaction, the reaction process can be closely monitored, and the consumption of raw materials and the formation of products can be observed by thin-layer chromatography. After the reaction is completed, the product is separated and purified by an appropriate method. The reaction solution is first poured into ice water to precipitate the product, and then filtered to obtain the crude product. After recrystallization, a suitable solvent, such as ethanol-water mixed solvent, is selected to recrystallize the crude product, remove impurities, and obtain pure p-nitroso chlorobenzene. After drying, the finished product is obtained
What are the precautions in storage and transportation of P-nitrosochlorobenzene?
P - nitrosochlorobenzene are organic compounds, and many matters must be paid attention to when storing and transporting them.
When storing, the first choice of environment is to choose. When placed in a cool and ventilated place, away from fire and heat sources. Because of its certain chemical activity, high temperature is easy to react and cause danger. The warehouse temperature should be controlled within an appropriate range, not too high.
Furthermore, it should be stored separately from oxidants and edible chemicals, and must not be mixed. This is because P - nitrosochlorobenzene comes into contact with oxidants, or has a violent chemical reaction, and even causes combustion and explosion. Mixed with edible chemicals, if there is leakage, it may cause food contamination and endanger human health.
Packaging is also crucial. It is necessary to ensure that the packaging is complete and sealed to prevent leakage. If the packaging is damaged and the material escapes, it will not only pollute the environment, but also increase the safety risk.
During transportation, the transportation vehicle should be equipped with the corresponding variety and quantity of fire equipment and leakage emergency treatment equipment. During driving, drivers must drive carefully and avoid violent operations such as sudden braking and sharp turns to prevent damage to the packaging.
In addition, when transporting, they should follow the specified route and do not stop in densely populated areas and residential areas. In the event of a leak, they can quickly evacuate the crowd and reduce the harm. Escort personnel also need to have professional knowledge, be familiar with emergency treatment methods, and closely monitor the whole transportation process to ensure safety.
P-nitrosochlorobenzene impact on the environment and human health
"Tiangong Kaiwu" was written by Song Yingxing in the Ming Dynasty. At that time, the discipline of chemistry had not yet been systematically developed, and it was difficult to accurately describe its impact on the environment and human health in its language. However, according to modern knowledge, it can be expressed as follows in ancient and elegant words:
"P-nitroso chlorobenzene, in this world, has various effects on the environment of the universe and human health. In the environment of the universe, P-nitroso chlorobenzene is scattered between heaven and earth, or sewage or soil, or the wind and clouds. If it is polluted in water and soil, the fertility of the soil will be damaged, the plants and trees raised may be mutated, the water will no longer be clear, and the aquatic creatures will also suffer from it, or die or change, and the ecological balance will be chaotic. Dyed in the wind and clouds, the breath that people breathe contains this filth, which is also the root cause of the curse.
As for human health, P-nitroso chlorobenzene is toxic. If people touch it, the skin is itchy, red and swollen, and the serious ones are ulcerated and sores. If it enters through the mouth and nose, it enters the lungs, causing chaos of qi and blood, and disturbing the regular transportation of the organs. The lungs control the breath, and the breath is poisoned by this, and the breathing is not smooth, and the coughing and asthma occur frequently; the heart controls the blood vessels, and it is also affected by its disorder, and the qi and blood are perverse, or it causes palpitations and stunned symptoms. After being in this situation for a long time, the organs are damaged, and the health is greatly reduced, and the life is worrying. Therefore, we should treat things carefully to prevent them
What are the main uses of P-nitrosochlorobenzene?
P-nitrosochlorobenzene (p-nitroso chlorobenzene) has a wide range of uses. First, it is an important intermediate in the field of organic synthesis. It can be derived from other organic compounds through many reaction paths. For example, through specific chemical reactions, different functional groups can be introduced to produce organic molecules with different structures, which is especially critical in the manufacture of fine chemical products.
Second, in the preparation of dyes, Jue is very powerful. It can be used as a basic raw material for synthetic dyes, and can be chemically converted to generate dye components with specific colors and properties. With its structural characteristics, it endows dyes with unique qualities such as color and fastness to meet the needs of textile, printing and dyeing industries.
Third, it is also useful in the field of pharmaceutical chemistry. Or can participate in the construction of drug molecules, with its special chemical activity, react with other compounds to form biologically active drug intermediates, and then promote the development and production of new drugs.
All these show that P-nitrosochlorobenzene plays an important role in many industries such as organic synthesis, dyes and medicine, and has a profound impact on the development of related industries.
What are the physical properties of P-nitrosochlorobenzene?
P - nitrosochlorobenzene, chemical substances are also. Its physical properties are particularly important, related to the use and characteristics of this substance.
First of all, its appearance is often crystalline, color or light yellow, and its crystal shape can be seen. It is uniform, like a natural micro-matter. The characteristic of this color state is the basis for identifying this substance.
times and melting point, about a specific temperature range. The number of melting points has a great influence on its physical state transformation in different environments. When heated to the melting point, it gradually melts from a solid state to a liquid state. This phase transition process is widely used in many fields such as chemical industry.
Furthermore, the boiling point is also a key property. When the boiling point is reached, the substance is converted from a liquid state to a gaseous state, and this process requires specific energy input. The boiling point is related to factors such as intermolecular forces. The boiling point of P-nitrosochlorobenzene determines its behavior in operations such as distillation.
The solubility cannot be ignored. In organic solvents, its solubility varies. Or it is easily soluble in certain types of organic solvents, but it is not well soluble in water. This property is the focus of consideration in separation, purification and reaction system construction.
In addition, density is also one of its physical properties. The value of density reflects the mass of its unit volume. Knowing its density can be accurately calculated in operations such as measurement and mixing to ensure the accuracy of experiments or production.
All these physical properties are related to each other, and the physical properties of the costructure P-nitrosochlorobenzene are of indispensable significance in many aspects such as chemical research and industrial production.
What is the chemistry of P-nitrosochlorobenzene?
P - nitrosochlorobenzene is an organic compound. It has unique chemical properties and is described below.
In this compound, the nitro group (-NO) and the chlorine atom (-Cl) are co-attached to the benzene ring. The benzene ring structure gives it a certain stability, but the presence of nitro and chlorine atoms makes it exhibit active chemical behavior.
In terms of reactivity, the nitro group is an electron-withdrawing group, which can reduce the electron cloud density of the benzene ring and reduce the electrophilic substitution activity of the benzene ring. However, this electron-withdrawing effect can enhance the activity of the adjacent and para-position nucleophilic substitution reactions. For example, when encountering nucleophilic reagents, the position of the chlorine atom is easily attacked by nucleophilic reagents and a substitution reaction occurs.
Furthermore, the nitro group can participate in the reduction reaction. Under suitable conditions, the nitro group can be gradually reduced to the amino group (-NH2O), which is a commonly used conversion path in organic synthesis.
And because of the chlorine atoms in its structure, under the action of specific metal catalysts, coupling reactions such as Ullmann reaction can occur, which can be connected with other organohalides or compounds containing active groups to expand the structural complexity of the molecule.
In addition, P - nitrosochlorobenzene in light, heat or specific chemical environments, or can undergo reactions such as intramolecular rearrangement to derive products with different structures. Due to its diverse chemical properties, it offers rich possibilities for organic synthetic chemistry and has potential applications in materials science, medicinal chemistry, and other fields.
What are P-nitrosochlorobenzene synthesis methods?
To make p-nitroso chlorobenzene, there are various synthesis methods. The first method is to use chlorobenzene as the starting material, nitrate to obtain p-nitrochlorobenzene, and then use appropriate reducing agents, such as sodium sulfide, iron powder, etc., to reduce the nitro group to nitroso group. This process requires controlling the reaction conditions, such as temperature, pH, etc., in order to achieve higher yield and purity.
The second method can be used to make nitrosobenzene first with benzene, followed by chlorination to introduce chlorine atoms into the para-position. However, the localization effect of nitroso groups in this approach is more complicated, and the reaction needs to be finely regulated to increase the formation ratio of p-nitroso chlorobenzene.
Furthermore, the reaction catalyzed by transition metals can be used. The synthesis of p-nitroso chlorobenzene is achieved by chlorine-containing aromatic derivatives and nitrosation reagents under the catalysis of specific transition metal catalysts such as palladium and copper. Such methods often have the advantages of mild reaction conditions and good selectivity, but the choice and dosage of catalysts have a great influence on the reaction.
When synthesizing p-nitrosochlorobenzene, various factors need to be carefully considered, such as the proportion of reactants, reaction temperature, reaction time, catalyst type and dosage, etc., in order to optimize the reaction and obtain high-quality products.
P-nitrosochlorobenzene to pay attention to when storing and transporting
"Works" says: "All products must be inspected for physical properties." P - Nitrochlorobenzene, if you want to avoid it, you should be careful and pay attention to all kinds of things.
The first priority is its chemical activity. This is a toxic and flammable thing. It should be placed in a place where it is dry and well-connected. It must not be near the fire source or the source, to prevent it from igniting and exploding, and it should be around. It is also necessary to avoid oxidation and raw materials, in order to prevent the strong reaction and dangerous life.
The second package must be solid and tight. Use glass bottles, plastic buckets and other devices to seal the package to prevent it from leaking. On the way, it is also necessary to prevent the container from breaking, causing p-nitrochlorobenzene to be exposed, polluting the environment and endangering humans and animals.
Furthermore, people who are affected by the accident will be affected by the accident. Familiar with its danger, it is necessary to deal with it urgently. If there is a leak, it should be isolated immediately to clear the crowd, and the fire should be prohibited. A small amount of leakage should be sucked with inert materials such as sand and vermiculite; if there is a large amount of leakage, it should be stored in an embankment or dig a pit, and moved to the collector with a pump, recycled or stored in the waste.
In this case, p-nitrochlorobenzene is dangerous, and everything should be done carefully and according to the rules, so as to avoid the accident.